Depakote combined with Levothyroxine Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Syncope Hospitalization 9/9/2005 77 Male 172 lb 1/5/2006 United States
Primary
Secondary
Concomitant
Syncope Hospitalization 9/9/2005 77 Male 172 lb 1/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Muscle Twitching 8/1/2005 42 168 lb 1/6/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 6/28/2005 49 Female 1/25/2006 France
Primary
Concomitant
Urticaria Disability 1/1/2004 Female 140 lb 3/7/2006 Consumer United States
Primary
Secondary
Concomitant
Visual Disturbance Hospitalization 1/2/2006 78 Female 2/24/2006 France
Primary
Secondary
Concomitant
Chest Pain Other Serious 5/15/2005 34 Female 275 lb 2/7/2006 Consumer United States
Primary
Concomitant
Tachycardia Other Serious 8/1/2005 Female 150 lb 4/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Agitation Hospitalization 4/1/2006 Male 280 lb 4/14/2006 Physician United States
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization 4/1/2006 Male 280 lb 4/26/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10 Male 4/25/2006 Physician United States
Primary
Concomitant
Paracentesis Other Serious 2/1/2006 60 Female 5/24/2006 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased Required Intervention 9/1/2005 15 Male 1/31/2006 Physician United States
Primary
Secondary
Concomitant
Insomnia 1/1/2005 59 Female 130 lb 4/3/2006 Consumer United States
Primary
Concomitant
Agitation Hospitalization 4/1/2006 Male 280 lb 6/15/2006 Physician United States
Primary
Concomitant
Overdose Life Threatening 1/17/2006 Female 176 lb 4/20/2006 Other Health Professional United States
Primary
Concomitant
Thyroid Disorder Other Serious 23 Female 7/27/2006 Other Health Professional United States
Primary
Concomitant
Rash Erythematous Hospitalization 6/26/2006 44 Male 183 lb 8/1/2006 Pharmacist United States
Primary
Concomitant
Agitation Hospitalization 4/1/2006 Male 280 lb 8/16/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2006 46 Male 9/15/2006 Physician Brazil
Primary
Secondary
Concomitant
Hypoglycaemia Unawareness Other Serious Female 9/19/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/6/2006 48 Male 12/14/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 10 Male 12/11/2006 Other Health Professional United States
Primary
Secondary
Thirst 8/23/2006 54 Female 10/19/2006 Physician United States
Primary
Concomitant
Vomiting 6/19/2006 72 Female 152 lb 1/29/2007 Consumer United States
Primary
Concomitant
Syncope Hospitalization 7/3/2006 89 Female 134 lb 11/10/2006 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Hospitalization 1/3/2007 Female 148 lb 2/6/2007 Consumer United States
Primary
Secondary
Concomitant
Nausea Other Serious 1/1/2003 Female 3/2/2007 Pharmacist United Kingdom
Primary
Concomitant
Nausea Other Serious 1/1/2003 Female 3/9/2007 Pharmacist United Kingdom
Primary
Concomitant
Osteoporosis Required Intervention 1/1/2003 63 Female 148 lb 8/17/2006 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/30/2007 84 Female 4/27/2007 Consumer France
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 7/1/2006 33 Female 330 lb 5/24/2007 United States
Primary
Secondary
Concomitant
Fall Hospitalization 12/24/2006 Female 6/1/2007 Physician France
Primary
Concomitant
Vomiting Other Serious 4/7/2007 56 Male 6/1/2007 Physician France
Primary
Concomitant
Repetitive Speech Other Serious 1/3/2007 80 Female 6/4/2007 Other Health Professional France
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 9/11/2006 48 Female 162 lb 6/1/2007 Consumer United States
Primary
Concomitant
Urinary Retention Hospitalization 2/20/2006 61 Female 224 lb 6/5/2007 Physician United States
Primary
Concomitant
Multiple Drug Overdose Intentional Hospitalization 49 Male 6/27/2007 Physician United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 2/20/2006 61 Female 224 lb 6/21/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 200 lb 7/11/2007 United States
Primary
Concomitant
Abortion Spontaneous Other Serious 3/4/2007 30 Female 7/26/2007 United States
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Other Serious 9/11/2006 48 Female 162 lb 7/25/2007 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 46 Male 8/1/2007 Other Health Professional France
Primary
Concomitant
Pain In Extremity Other Serious Male 8/20/2007 Other Health Professional France
Primary
Concomitant
Therapeutic Response Decreased 7/1/2007 Female 8/29/2007 Consumer United States
Primary
Concomitant
Alopecia 46 Female 182 lb 9/18/2007 United States
Primary
Concomitant
Therapeutic Response Decreased 7/1/2007 Female 10/8/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 4/7/2007 56 Male 10/12/2007 Physician France
Primary
Concomitant
Interacting
Tremor Hospitalization 1/1/2007 Female 187 lb 10/30/2007 Consumer United States
Primary
Secondary
Concomitant
Tremor Hospitalization 1/1/2007 Female 187 lb 11/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/29/2007 Male 11/8/2007 Physician France
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/5/2007 Male 231 lb 11/19/2007 Other Health Professional United States
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 9/11/2006 48 Female 162 lb 11/20/2007 Consumer United States
Primary
Concomitant
Psychiatric Decompensation Other Serious 7/1/2007 Female 11/28/2007 Other Health Professional France
Primary
Secondary
Concomitant
Mania Other Serious 7/1/2007 Female 11/29/2007 Other Health Professional France
Primary
Secondary
Concomitant
Rash Hospitalization 6/1/2007 59 Male 213 lb 11/26/2007 United States
Primary
Concomitant
Swelling 11/10/2007 54 Female 196 lb 12/10/2007 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 38 Female 12/14/2007 Physician United Kingdom
Primary
Concomitant
Rash Hospitalization 6/1/2007 59 Male 213 lb 12/12/2007 United States
Primary
Concomitant
Vision Blurred Other Serious 4/26/2000 Male 301 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2007 Female 1/25/2008 Consumer United States
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 5/24/2007 42 Female 174 lb 1/31/2008 Physician United States
Primary
Concomitant
Speech Disorder Other Serious 12/7/2007 Female 189 lb 2/1/2008 United States
Primary
Concomitant
Respiratory Distress Hospitalization 9/22/2006 Female 2/4/2008 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 49 Male 1/30/2008 Physician United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 60 Female 213 lb 2/12/2008 Physician United States
Primary
Concomitant
Tremor 5/10/2007 2/7/2008 Pharmacist United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 60 Female 213 lb 2/13/2008 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 1/8/2008 Female 117 lb 2/25/2008 Pharmacist United States
Primary
Concomitant
Mania Hospitalization 6/1/2007 59 Male 228 lb 2/26/2008 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2008 Female 110 lb 3/4/2008 Other Health Professional United States
Primary
Concomitant
Arthralgia 9/28/2007 40 Female 2/15/2008 United States
Primary
Concomitant
Suicidal Ideation Hospitalization 7/1/2007 Female 187 lb 3/11/2008 United States
Primary
Concomitant
Weight Increased 11/29/2007 59 Female 187 lb 3/4/2008 United States
Primary
Concomitant
Breast Cancer Hospitalization 11/20/2007 80 Female 3/13/2008 Consumer United Kingdom
Primary
Concomitant
Skin Necrosis Other Serious 2/28/2008 48 Female 147 lb 3/10/2008 Other Health Professional United States
Primary
Concomitant
Ventricular Septal Defect Hospitalization 9/22/2006 Female 1 lb 4/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Toxicity Death 9/11/2004 Female 125 lb 4/10/2008 Lawyer United States
Primary
Concomitant
Platelet Count Decreased 3/1/2007 Male 35 lb 4/11/2008 Physician United States
Primary
Concomitant
Tremor 5/1/2007 Male 260 lb 4/11/2008 Consumer United States
Primary
Concomitant
Vision Blurred 7/1/2007 Female 182 lb 4/11/2008 Consumer United States
Primary
Concomitant
Tremor 7/1/2007 Female 243 lb 4/11/2008 Consumer United States
Primary
Concomitant
Rash Generalised Hospitalization 2/3/2004 Female 150 lb 4/11/2008 Consumer United States
Primary
Concomitant
Mania Hospitalization 11/20/2007 Female 190 lb 4/11/2008 Consumer United Kingdom
Primary
Concomitant
Ventricular Septal Defect Hospitalization 9/22/2006 Female 1 lb 4/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 6/1/2007 49 Male 4/21/2008 Physician United States
Primary
Concomitant
Ventricular Septal Defect Hospitalization 9/22/2006 Female 1 lb 4/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tracheal Obstruction Death 10/22/2007 Male 157 lb 4/18/2008 Other Health Professional United States
Primary
Concomitant
Swelling Hospitalization 4/12/2008 47 Female 200 lb 5/6/2008 Physician United States
Primary
Concomitant
Tremor Other Serious 11/14/2006 70 Female 5/9/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 3/1/2008 71 Female 5/8/2008 France
Primary
Secondary
Concomitant
Ventricular Septal Defect Hospitalization 9/22/2006 Female 1 lb 5/12/2008 Pharmacist United States
Primary
Concomitant
Ventricular Septal Defect Hospitalization 9/22/2006 Female 1 lb 5/16/2008 Pharmacist United States
Primary
Concomitant
Renal Failure Life Threatening 3/1/2008 71 Female 5/17/2008 France
Primary
Secondary
Concomitant
Swelling Hospitalization 4/12/2008 47 Female 200 lb 5/17/2008 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 7/1/2007 Female 187 lb 5/20/2008 United States
Primary
Concomitant
Nephrogenic Diabetes Insipidus Life Threatening 4/18/2008 Female 5/23/2008 Other Health Professional France
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 2/1/2006 Female 5/19/2008 Consumer United States
Primary
Concomitant
Tremor Life Threatening 4/1/2008 71 Female 5/13/2008 France
Primary
Secondary
Concomitant
Tremor Life Threatening 4/1/2008 71 Female 5/19/2008 Other Health Professional France
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 2/1/2006 53 Female 6/18/2008 Consumer United States
Primary
Concomitant
Swelling Hospitalization 4/2/2008 Female 200 lb 6/24/2008 Physician United States
Primary
Secondary
Concomitant
Ventricular Septal Defect Hospitalization 9/22/2006 Female 1 lb 6/24/2008 Pharmacist United States
Primary
Concomitant
Wheelchair User Other Serious 4/1/2008 Female 140 lb 6/30/2008 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 2/1/2006 53 Female 6/27/2008 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 2/27/2008 Male 7/2/2008 United States
Primary
Secondary
Concomitant
Drug Toxicity Death 9/11/2004 Female 125 lb 7/22/2008 Other Health Professional United States
Primary
Concomitant
Vision Blurred 11/1/2007 56 Female 160 lb 9/2/2008 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/23/2008 50 Female 9/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Urine Sodium Decreased Hospitalization 3/15/2008 Female 10/1/2008 Other Health Professional France
Primary
Secondary
Concomitant
Drug Level Below Therapeutic Hospitalization 8/1/2008 54 Female 10/2/2008 Consumer United States
Primary
Concomitant
Pain Hospitalization 8/1/2008 Female 119 lb 11/13/2008 Consumer Brazil
Primary
Secondary
Concomitant
Ovarian Disorder Hospitalization 8/1/2008 Female 119 lb 11/17/2008 Consumer Brazil
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 10/18/2008 Female 11/24/2008 Pharmacist United Kingdom
Primary
Concomitant
Chest Pain Female 12/1/2008 Physician United States
Primary
Concomitant
Ovarian Disorder Hospitalization 8/1/2008 Female 119 lb 12/3/2008 Consumer Brazil
Primary
Secondary
Concomitant
Rash Other Serious 6/23/2008 42 Female 12/5/2008 Consumer United States
Primary
Concomitant
Condition Aggravated Other Serious 9/25/2008 Female 250 lb 12/10/2008 Consumer United States
Primary
Concomitant
Hyperprolactinaemia Other Serious 3/11/2008 Female 217 lb 12/8/2008 Pharmacist United States
Primary
Concomitant
Troponin I Increased Hospitalization 1/30/2008 Female 213 lb 1/9/2009 Physician United States
Primary
Concomitant
Mania 10/27/2007 59 Female 269 lb 1/13/2009 Consumer United States
Primary
Concomitant
Motor Dysfunction 16 Male 328 lb 1/13/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2008 51 Female 169 lb 2/17/2009 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 10/1/2007 48 Female 2/27/2009 Consumer United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 Female 213 lb 3/9/2009 Physician United States
Primary
Concomitant
Condition Aggravated Other Serious 9/25/2008 Female 250 lb 3/12/2009 Consumer United States
Primary
Concomitant
Parkinson's Disease 10/1/2005 3/12/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2007 Female 108 lb 3/12/2009 Physician United States
Primary
Concomitant
Benign Hepatic Neoplasm 1/1/1994 Female 190 lb 3/12/2009 Consumer United States
Primary
Concomitant
Tremor 1/1/1998 Female 130 lb 3/12/2009 Consumer United States
Primary
Concomitant
Alopecia 7/1/2008 Female 124 lb 3/12/2009 Consumer United States
Primary
Concomitant
Polyp 1/30/2009 Female 120 lb 3/14/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/4/2002 50 Male 290 lb 3/26/2009 Other Health Professional United States
Primary
Concomitant
Interacting
Surgical Procedure Repeated Hospitalization 6/6/2008 49 Female 110 lb 4/3/2009 United States
Primary
Concomitant
Weight Increased Hospitalization Female 4/17/2009 Consumer United States
Primary
Secondary
Concomitant
Vocal Cord Disorder Other Serious 11/1/2007 56 Male 380 lb 4/17/2009 Lawyer United States
Primary
Concomitant
Urinary Incontinence Other Serious 7/11/2001 63 Male 220 lb 4/20/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 53 Female 146 lb 4/24/2009 Consumer United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 10/1/2007 48 Female 4/27/2009 Consumer United States
Primary
Concomitant
Rectal Fissure Hospitalization 3/14/2009 Female 4/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Rectal Fissure Hospitalization 3/19/2009 Female 5/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 7/1/2005 19 Female 162 lb 5/18/2009 United States
Primary
Concomitant
Tremor Hospitalization 12/1/2003 55 Female 198 lb 5/19/2009 United States
Primary
Concomitant
Pituitary Tumour Other Serious 4/1/2009 51 Female 5/13/2009 United States
Primary
Concomitant
Rectal Fissure Hospitalization 3/19/2009 Female 5/21/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Potentiating Drug Interaction Other Serious 1/1/2009 64 Female 5/22/2009 Consumer United States
Primary
Concomitant
Rectal Fissure Hospitalization 3/19/2009 Female 6/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/18/2008 14 Male 78 lb 6/25/2009 Consumer United States
Primary
Concomitant
Swelling Hospitalization 54 Female 176 lb 6/26/2009 Consumer Brazil
Primary
Concomitant
Tremor Hospitalization 1/1/2004 140 lb 6/30/2009 Physician United States
Primary
Concomitant

Drug Data