Depakote combined with Lamotrigine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urticaria Disability 1/1/2004 Female 140 lb 3/7/2006 Consumer United States
Primary
Secondary
Concomitant
Missed Labour Other Serious 6/23/2005 31 Female 3/14/2006 Physician Poland
Primary
Concomitant
Pyrexia Hospitalization 2/28/2006 61 Male 5/12/2006 Other Health Professional France
Primary
Concomitant
Interacting
Pancreatitis Hospitalization 1/1/1995 31 Female 3/21/2005 United States
Primary
Secondary
Concomitant
Death Death 12/24/2005 45 Female 12/29/2005 Physician United States
Primary
Concomitant
Small For Dates Baby Other Serious 5/5/2004 Female 5/26/2006 Physician United States
Primary
Secondary
Polydactyly Congenital Anomaly Male 7/26/2005 Other Health Professional United States
Primary
Secondary
Vomiting Disability 3/15/2005 28 Male 190 lb 6/15/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Effect Decreased 10/1/2005 63 Male 240 lb 4/3/2006 Consumer United States
Primary
Concomitant
Status Epilepticus Hospitalization 62 Female 7/7/2006 Physician United States
Primary
Secondary
Walking Disability Hospitalization 5/1/2006 74 Female 7/3/2006 Pharmacist United Kingdom
Primary
Concomitant
Granulocytopenia Required Intervention 1/25/2006 43 Male 150 lb 3/21/2006 United States
Primary
Secondary
Concomitant
Leukopenia 6/2/2006 57 Male 8/10/2006 Physician United Kingdom
Primary
Concomitant
Mania Hospitalization 1/1/2006 Male 8/17/2006 Physician United States
Primary
Secondary
Hallucination Other Serious Female 8/21/2006 Physician United States
Primary
Secondary
Thrombocytopenia Other Serious 35 Male 8/24/2006 Physician Brazil
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2004 45 Male 175 lb 7/14/2006 Physician United States
Primary
Concomitant
Uterine Haemorrhage Other Serious 2/15/2002 0 Male 7 lb 9/15/2006 Other Health Professional United States
Primary
Secondary
Uterine Haemorrhage Other Serious 2/15/2002 0 Male 7 lb 9/15/2006 Other Health Professional United States
Primary
Secondary
Tongue Disorder Other Serious 1/8/2003 Female 9/20/2006 Consumer United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Life Threatening 10/10/2006 Male 70 lb 10/23/2006 Consumer United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 1/1/2002 Female 12/21/2006 Consumer United States
Primary
Secondary
Concomitant
Interacting
Myoclonus Other Serious 1/24/2007 Physician United States
Primary
Secondary
Stevens-johnson Syndrome Hospitalization 1/1/2006 9 Male 2/2/2007 Physician United States
Primary
Secondary
Urticaria Hospitalization 6/1/2006 22 Male 2/9/2007 Consumer United States
Primary
Secondary
Serotonin Syndrome Hospitalization 10/1/2006 51 Female 228 lb 2/14/2007 Physician United States
Primary
Concomitant
Suicide Attempt Life Threatening 1/1/1996 Female 140 lb 2/16/2007 Consumer United States
Primary
Secondary
Concomitant
Hepatic Failure Hospitalization Female 2/16/2007 Physician United States
Primary
Interacting
Weight Increased Other Serious 1/1/2003 Female 140 lb 2/21/2007 Physician United States
Primary
Secondary
Concomitant
Mood Altered Other Serious Male 3/15/2007 Consumer United States
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 10/1/2006 51 Female 224 lb 4/23/2007 Physician United States
Primary
Concomitant
Talipes Congenital Anomaly Male 6/18/2007 Other Health Professional United States
Primary
Concomitant
Medication Error Hospitalization 3/29/2007 Male 7/6/2007 United States
Primary
Secondary
Concomitant
Talipes Congenital Anomaly Male 7/25/2007 Other Health Professional United States
Primary
Concomitant
Convulsion Other Serious 6 Male 10/24/2007 Consumer United States
Primary
Secondary
Weight Increased Other Serious 8/8/2007 Female 2/1/2008 Consumer United States
Primary
Secondary
Concomitant
Sinus Bradycardia Other Serious 42 Male 3/19/2008 United Kingdom
Primary
Concomitant
Sinus Bradycardia Other Serious 42 Male 3/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Drug Level Decreased 9/1/2006 Male 4/11/2008 Physician United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 3/23/2007 Male 30 lb 4/11/2008 Physician United States
Primary
Secondary
Concomitant
Alopecia 3/1/2007 Female 160 lb 4/11/2008 Consumer United States
Primary
Concomitant
Drug Ineffective 1/1/1998 Male 280 lb 4/11/2008 Consumer United States
Primary
Concomitant
Skin Burning Sensation Male 4/11/2008 Physician United States
Primary
Concomitant
Agranulocytosis Other Serious 1/1/2007 Female 4/11/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/9/2007 Male 105 lb 4/11/2008 Consumer United States
Primary
Secondary
Interacting
Drug Ineffective Male 250 lb 4/11/2008 Consumer United States
Primary
Concomitant
Influenza Like Illness 3/1/2007 Female 180 lb 4/11/2008 Consumer United States
Primary
Concomitant
Vision Blurred 7/1/2007 Female 182 lb 4/11/2008 Consumer United States
Primary
Concomitant
Viral Infection Other Serious 7/1/2007 Male 280 lb 5/19/2008 Consumer United States
Primary
Secondary
Concomitant
Viral Infection Other Serious 7/1/2007 Male 280 lb 6/5/2008 Consumer United States
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 5/23/2008 27 Female 6/12/2008 Pharmacist United States
Primary
Secondary
Vagus Nerve Disorder Other Serious 1/1/1998 Female 7/21/2008 Consumer United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 4/1/2007 Male 215 lb 7/24/2008 Consumer United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 1/1/2007 Male 230 lb 7/29/2008 Consumer United States
Primary
Concomitant
Thinking Abnormal Life Threatening 1/1/2002 Male 215 lb 7/31/2008 Consumer United States
Primary
Secondary
Concomitant
Thinking Abnormal Life Threatening 1/1/2002 Male 215 lb 8/1/2008 Consumer United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 7/28/2008 Male 135 lb 8/7/2008 Consumer United States
Primary
Concomitant
Petit Mal Epilepsy Hospitalization 11/1/2007 6 Female 8/22/2008 Consumer United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 8/1/2008 Female 8/29/2008 Pharmacist United States
Primary
Concomitant
Swelling Hospitalization 1/1/2008 Female 282 lb 9/8/2008 Physician France
Primary
Secondary
Concomitant
Thinking Abnormal Life Threatening 1/1/2002 Male 215 lb 9/15/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting 11/1/2006 Female 69 lb 10/8/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 9/30/2008 15 Female 73 lb 10/9/2008 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2004 26 Female 11/3/2008 Consumer United States
Primary
Secondary
Concomitant
Tachypnoea Other Serious 10/5/2008 Female 225 lb 12/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 12/26/2008 Other Health Professional United States
Primary
Secondary
Tachypnoea Other Serious 47 Female 1/12/2009 Physician
Primary
Concomitant
Tachypnoea Other Serious 47 Female 1/9/2009 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/1/2008 51 Female 169 lb 2/17/2009 Consumer United States
Primary
Concomitant
Hepatic Failure Hospitalization Female 2/26/2009 Physician United States
Primary
Secondary
Convulsion Other Serious 8/1/2008 Male 2/27/2009 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased 10/9/2008 59 Male 2/27/2009 Physician United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 10/1/2008 40 Female 2/27/2009 Consumer United States
Primary
Concomitant
Rhinorrhoea 11/1/2008 53 Female 2/27/2009 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/26/2009 3/2/2009 Physician United Kingdom
Primary
Concomitant
Ataxia 3/12/2009 Physician United States
Primary
Concomitant
Breast Enlargement 3/12/2009 Physician United States
Primary
Concomitant
Weight Increased 3/12/2009 Physician United States
Primary
Concomitant
Rash 3/12/2009 Consumer United States
Primary
Concomitant
Confusional State 3/12/2009 Physician United States
Primary
Concomitant
Vomiting 7/1/2007 Female 238 lb 3/12/2009 Pharmacist United States
Primary
Concomitant
Benign Hepatic Neoplasm 1/1/1994 Female 190 lb 3/12/2009 Consumer United States
Primary
Concomitant
Convulsion Other Serious Female 150 lb 3/12/2009 Other Health Professional United States
Primary
Concomitant
Testicular Disorder Congenital Anomaly 7/17/1999 Male 3/12/2009 United States
Primary
Secondary
Syndactyly Congenital Anomaly 6/5/1999 Male 8 lb 3/12/2009 United States
Primary
Secondary
Vomiting Other Serious 10/21/2002 45 Female 136 lb 4/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Other Serious 1/1/1999 39 Male 202 lb 7/10/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 44 Male 193 lb 7/10/2009 United States
Primary
Concomitant
Talipes Congenital Anomaly Male 8/25/2009 Other Health Professional United States
Primary
Secondary
Vision Blurred Other Serious 4/3/2003 54 Female 245 lb 9/3/2009 United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 4/7/2003 38 Female 197 lb 9/23/2009 United States
Primary
Concomitant
Weight Increased 18 Female 160 lb 9/23/2009 Consumer United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 7/6/2009 49 Female 9/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Other Serious 10/5/2008 47 Female 225 lb 10/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/25/2009 48 Female 10/22/2009 Pharmacist United States
Primary
Secondary
Concomitant
Tachypnoea Other Serious 10/5/2008 47 10/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Other Serious 10/5/2008 47 Female 10/22/2009 United Kingdom
Primary
Concomitant
Tachypnoea Other Serious 10/5/2008 47 Female 225 lb 10/27/2009 Physician
Primary
Secondary
Concomitant
Rash Hospitalization Male 11/3/2009 Physician United Kingdom
Primary
Concomitant
Rash Hospitalization 11/24/2009 Physician United States
Primary
Secondary
Stevens-johnson Syndrome Other Serious 7/31/2008 55 Male 12/23/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Product Substitution Issue Other Serious 10/1/2009 29 Male 138 lb 11/18/2009 United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 11/5/2009 48 Male 12/29/2009 Physician United States
Primary
Secondary
Concomitant
Rash Maculo-papular Hospitalization 9/29/2009 37 Female 1/25/2010 Other Health Professional France
Primary
Secondary
Paraesthesia 12/1/2008 28 Male 2/26/2010 Consumer United States
Primary
Concomitant
Vomiting 2/24/2009 20 Male 3/17/2009 Physician United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/2/2010 14 Female 7/7/2010 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 12/1/2009 48 Male 6/9/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting 11/1/2007 60 Female 110 lb 7/17/2010 Consumer United States
Primary
Concomitant
Headache 11/13/2007 60 Female 110 lb 7/17/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2005 40 Female 228 lb 9/17/2010 United States
Primary
Concomitant
Pancreatitis Other Serious 1/1/2005 33 Female 182 lb 9/20/2010 United States
Primary
Concomitant
Post-traumatic Stress Disorder Other Serious 8/1/2010 63 Male 190 lb 9/23/2010 Consumer United States
Primary
Concomitant
Drug Ineffective 9/8/2010 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 2/19/2010 57 Male 172 lb 9/30/2010 Pharmacist United States
Primary
Secondary
Concomitant
Mental Disorder Hospitalization 45 Female 11/8/2010 United States
Primary
Secondary
Mental Disorder Hospitalization 45 Female 12/1/2010 Other Health Professional United States
Primary
Secondary
Thrombocytopenia Other Serious 1/1/2004 21 Male 176 lb 12/1/2010 Physician Brazil
Primary
Concomitant
Drug Interaction Hospitalization Female 17 lb 2/23/2011 Consumer Brazil
Primary
Concomitant
Interacting
Tremor 45 Female 2/28/2011 Consumer United States
Primary
Concomitant
Hostility 17 Male 2/28/2011 Consumer United States
Primary
Concomitant
Vision Blurred 53 Female 2/28/2011 Consumer United States
Primary
Concomitant
Pain In Extremity 7 Male 2/28/2011 Consumer United States
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Other Serious Female 3/14/2011 Consumer United States
Primary
Secondary
Brain Operation Hospitalization 1/1/2001 22 Female 4/20/2011 Consumer United States
Primary
Secondary
Withdrawal Syndrome Hospitalization 3/1/2009 49 Female 130 lb 4/22/2011 United States
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 1/10/2011 72 Female 4/25/2011 Other Health Professional France
Primary
Secondary
Concomitant
Convulsion Hospitalization 1/1/2001 22 Female 4/29/2011 Consumer United States
Primary
Secondary
Haemoglobin Decreased Hospitalization 3/22/2011 65 Female 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cholecystitis Other Serious 11/1/2008 37 Female 204 lb 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Other Serious 11/1/2008 37 Female 204 lb 5/31/2011 Consumer United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 2/1/2008 50 Male 6/2/2011 Consumer United States
Primary
Secondary
Concomitant
Asthma Hospitalization 10/5/2008 47 Female 225 lb 6/5/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Spinal X-ray Disability Female 6/5/2011 Physician United Kingdom
Primary
Concomitant
Tachycardia Other Serious 10/5/2008 47 Female 225 lb 6/12/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Asthma Hospitalization 10/5/2008 47 Female 225 lb 6/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Asthma Hospitalization 10/5/2008 47 Female 225 lb 6/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 10/5/2008 47 Female 225 lb 6/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urticaria Other Serious 1/1/2011 23 Female 6/10/2011 Consumer United States
Primary
Secondary
Concomitant
C-reactive Protein Increased Hospitalization 10/5/2008 47 Female 6/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Monocyte Count Increased Hospitalization 10/5/2008 47 Female 225 lb 6/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Granulocytopenia Other Serious 6/18/2010 19 Male 6/22/2011 Pharmacist United States
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Hospitalization 10/5/2008 47 Female 225 lb 6/21/2011
Primary
Secondary
Concomitant
Body Temperature Increased Other Serious 10/5/2008 47 Female 6/21/2011 Physician Denmark
Primary
Concomitant
Eosinophil Count Decreased Hospitalization 7/5/2011 41 Female 7/20/2011 Physician United States
Primary
Concomitant
Hypotension Hospitalization 7/5/2011 41 Female 8/18/2011 Consumer United States
Primary
Concomitant
Dry Skin Hospitalization 3/1/2011 75 Female 8/25/2011 Consumer United States
Primary
Secondary
Concomitant
Infectious Mononucleosis Other Serious 25 Female 8/26/2011 Physician United States
Primary
Secondary
Monocyte Count Increased Hospitalization 10/5/2008 47 Female 225 lb 9/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 42 Female 9/7/2011 Physician United States
Primary
Concomitant
Interacting

Drug Data