Depakote combined with Keppra

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pneumonia Other Serious 1/2/2006 Male 205 lb 1/5/2006 United States
Primary
Concomitant
Mitral Valve Disease Other Serious 11/20/2004 57 Male 251 lb 1/19/2006 United States
Primary
Concomitant
Pneumonia Hospitalization 1/2/2006 69 Male 205 lb 1/24/2006 United States
Primary
Secondary
Concomitant
Catatonia Other Serious NotSpecified 1/26/2006 Physician United States
Primary
Concomitant
Rash Other Serious 4/11/2005 15 Male 2/28/2006 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Male 2/28/2006 Consumer United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 1/1/2006 48 Female 3/15/2006 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 3/5/2006 30 Male 3/13/2006 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2006 20 Male 3/24/2006 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 3/5/2006 30 Male 3/30/2006 United States
Primary
Concomitant
Rash Hospitalization 3/1/2006 25 Male 3/29/2006 Physician United States
Primary
Concomitant
Drug Interaction Other Serious 3/5/2006 30 Male 4/17/2006 Other Health Professional United States
Primary
Secondary
Somnolence Other Serious 8/19/2005 26 Male 136 lb 2/8/2006 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 5/18/2006 35 Male 177 lb 5/31/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/3/2006 20 Male 5/23/2006 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2004 Female 108 lb 5/25/2006 United States
Primary
Secondary
Concomitant
Syncope Other Serious 1/1/2001 22 Female 153 lb 5/23/2006 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity 12/29/2005 43 Male 145 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2004 Female 108 lb 6/14/2006 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 Female 108 lb 6/21/2006 United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 62 Female 7/3/2006 Consumer United States
Primary
Secondary
Status Epilepticus Hospitalization 6/1/2006 62 Female 6/28/2006 Physician United States
Primary
Secondary
Tremor Hospitalization 6/1/2006 3 Male 7/10/2006 Physician United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/2/2006 69 Male 205 lb 7/13/2006 Physician United States
Primary
Secondary
Concomitant
Blood Glucose Increased 58 Male 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/2/2006 69 Male 205 lb 7/21/2006 Physician United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2003 79 Female 154 lb 8/1/2006 Consumer United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 7/1/2006 51 Female 161 lb 8/7/2006
Primary
Secondary
Concomitant
Malaise Other Serious 7/1/2006 Female 161 lb 8/7/2006
Primary
Secondary
Concomitant
Inappropriate Schedule Of Drug Administration Hospitalization 1/1/2006 78 Female 9/5/2006 Consumer United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 7/1/2006 Female 161 lb 9/22/2006 Consumer United States
Primary
Secondary
Concomitant
Malaise Other Serious 7/1/2006 Female 161 lb 10/11/2006 Consumer United States
Primary
Secondary
Concomitant
Sudden Death Death 8/20/2006 11 Male 10/26/2006 Italy
Primary
Secondary
Psychotic Disorder Other Serious 18 Male 10/25/2006 Consumer United States
Primary
Concomitant
Convulsion Other Serious 35 Male 11/15/2006 Physician United States
Primary
Concomitant
Multiple Sclerosis Other Serious Female 11/22/2006 Physician United States
Primary
Secondary
Pharmaceutical Product Complaint Other Serious 7/1/2006 Female 161 lb 12/14/2006 Consumer United States
Primary
Secondary
Concomitant
Urinary Incontinence Required Intervention 11/4/2006 Female 119 lb 12/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Partial Seizures Other Serious 11/16/2006 55 Female 12/21/2006 Physician United States
Primary
Concomitant
Somnolence 4/6/2006 9 Male 12/29/2006 Consumer United States
Primary
Concomitant
Physical Assault Hospitalization 11/29/2006 34 Male 1/9/2007 Pharmacist United States
Primary
Concomitant
Convulsion Other Serious 9/27/2006 15 Male 11/7/2006 Consumer United States
Primary
Concomitant
Neoplasm Progression Hospitalization 35 Male 1/16/2007 Italy
Primary
Secondary
Muscular Weakness Hospitalization 2/1/2007 Male 172 lb 2/7/2007 United States
Primary
Secondary
Concomitant
Dizziness Female 2/28/2007 Consumer United States
Primary
Secondary
Concomitant
Rash 11/14/2006 13 Female 3/1/2007 Other Health Professional United States
Primary
Concomitant
Pancytopenia Other Serious 36 Female 3/14/2007 Physician United States
Primary
Secondary
Tardive Dyskinesia Required Intervention 40 Female 8/21/2004 Physician United States
Primary
Concomitant
Hyponatraemia Hospitalization 2/1/2007 Male 172 lb 3/27/2007 United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 9/17/2002 Male 146 lb 4/11/2007 Pharmacist United States
Primary
Concomitant
Refusal Of Treatment By Relative Hospitalization 3/25/2007 19 Male 235 lb 5/10/2007 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 7/5/2005 Female 93 lb 6/13/2007 Lawyer United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/11/2007 13 Male 105 lb 6/19/2007 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 7/5/2005 Female 93 lb 7/10/2007 Lawyer United States
Primary
Secondary
Concomitant
Weight Increased 1/1/2006 7/13/2007 Consumer United States
Primary
Concomitant
Vitamin B12 Increased Death 36 Female 135 lb 8/22/2007 Other Health Professional United States
Primary
Secondary
Myelopathy Other Serious 44 Male 122 lb 8/20/2007 Pharmacist United States
Primary
Concomitant
Vitamin B12 Increased Other Serious 36 Female 135 lb 8/27/2007 Physician United States
Primary
Secondary
Vitamin B12 Increased Death 36 Female 134 lb 9/11/2007 Physician United States
Primary
Secondary
Oedema Female 9/19/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2007 10 Male 9/28/2007 Physician United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/1/2003 18 Female 126 lb 10/30/2007 United States
Primary
Secondary
Tachycardia Other Serious 1/1/2003 18 Female 126 lb 11/22/2007 United States
Primary
Secondary
Recurrent Cancer Death 10/8/2007 37 Male 168 lb 11/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 8/24/2007 43 Male 12/20/2007 Physician United States
Primary
Concomitant
Respiratory Failure Life Threatening 9/1/2007 Male 12/20/2007 Physician United States
Primary
Concomitant
Respiratory Failure Life Threatening 7/15/2007 Male 12/20/2007 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 9/27/2007 19 Female 1/3/2008 Pharmacist United States
Primary
Concomitant
Convulsion Other Serious 9/27/2006 15 Male 11/20/2007 Consumer United States
Primary
Concomitant
Off Label Use Other Serious 1/16/2008 United States
Primary
Concomitant
Suicide Attempt Hospitalization 6/17/2003 31 Female 1/11/2008 United States
Primary
Concomitant
Tremor Life Threatening 7/15/2007 Male 2/15/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 9/1/2007 Male 2/15/2008 Physician United States
Primary
Concomitant
Respiratory Arrest Other Serious 8/24/2007 43 Male 2/20/2008 Physician United States
Primary
Concomitant
Cd4 Lymphocytes Decreased Hospitalization Male 3/20/2008 Pharmacist United States
Primary
Concomitant
Hepatic Failure Death Female 3/20/2008 Physician United States
Primary
Concomitant
Tremor Other Serious 2/1/2008 Female 4/1/2008 Consumer United States
Primary
Concomitant
Hepatic Failure Death Female 4/1/2008 Physician United States
Primary
Concomitant
Death Other Serious 4/6/2008 Male 4/21/2008 Physician United States
Primary
Concomitant
Viral Infection Life Threatening 2/1/2008 31 Female 132 lb 4/21/2008 Physician Saudi Arabia
Primary
Secondary
Unresponsive To Stimuli Hospitalization 36 Female 135 lb 4/28/2008 Other Health Professional United States
Primary
Secondary
Tracheal Obstruction Death 10/22/2007 Male 157 lb 4/18/2008 Other Health Professional United States
Primary
Concomitant
Bone Marrow Failure Life Threatening 1/1/2008 76 Male 4/24/2008 Italy
Primary
Concomitant
Visual Acuity Reduced Other Serious 5/1/2008 Male 209 lb 6/10/2008 Consumer United States
Primary
Concomitant
Treatment Noncompliance Other Serious 3/25/2008 49 Male 6/25/2008 Pharmacist United States
Primary
Concomitant
Osteoporosis Other Serious 1/1/2008 Male 130 lb 7/29/2008 United States
Primary
Concomitant
Self-medication Hospitalization 6/5/2008 43 Female 7/31/2008 Consumer United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death Male 8/15/2008 Lawyer United States
Primary
Concomitant
Petit Mal Epilepsy Hospitalization 11/1/2007 6 Female 8/22/2008 Consumer United States
Primary
Secondary
Concomitant
Mental Status Changes Other Serious 4/1/2008 72 Female 170 lb 8/19/2008 Consumer United States
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 9 Female 40 lb 8/25/2008 Consumer United States
Primary
Concomitant
Wheelchair User Disability 7/1/2008 87 Female 110 lb 8/25/2008 Consumer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 36 Female 9/5/2008 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 5/1/2008 Male 171 lb 9/29/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 7/26/2008 37 Male 290 lb 10/6/2008 Pharmacist United States
Primary
Concomitant
Headache 5/27/2008 55 Male 9/16/2008 United States
Primary
Concomitant
Drug Interaction Other Serious 84 Female 133 lb 10/23/2008 Other Health Professional United States
Primary
Concomitant
Status Epilepticus Hospitalization 6/5/2008 43 Female 11/25/2008 Physician
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 11/1/2008 Male 194 lb 12/1/2008 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 9/16/2008 28 Male 130 lb 12/1/2008 Physician United States
Primary
Concomitant
Swelling Hospitalization 9/1/2008 39 Female 99 lb 12/22/2008 Consumer United States
Primary
Concomitant
Shunt Malfunction Hospitalization 9/21/2008 29 Female 210 lb 1/2/2009 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 11/1/2008 Male 194 lb 1/21/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 1/1/2006 Female 131 lb 1/21/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 1/1/2006 Female 131 lb 1/21/2009 Consumer United States
Primary
Concomitant
Neutrophil Count Decreased Other Serious 10/14/2008 Male 2/10/2009 Physician United States
Primary
Secondary
Concomitant
Granulocytopenia Other Serious 10/14/2008 Male 2/11/2009 Consumer United States
Primary
Concomitant
Rhabdomyolysis Other Serious 9/13/2008 42 Male 2/11/2009 Physician United States
Primary
Concomitant
Premature Baby Other Serious 5/1/2008 Male 8 lb 2/23/2009 Physician United States
Primary
Concomitant
Premature Labour Hospitalization 5/1/2008 31 Female 2/23/2009 Physician United States
Primary
Concomitant
Premature Baby Other Serious 5/1/2008 Male 8 lb 2/23/2009 Physician United States
Primary
Concomitant
Grand Mal Convulsion Hospitalization 5/1/2008 31 Female 2/23/2009 Physician United States
Primary
Concomitant
Convulsion Other Serious 8/1/2008 Male 2/27/2009 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 42 Male 2/20/2009 Physician United States
Primary
Concomitant
Hepatic Failure Other Serious 54 Female 3/12/2009 Physician United States
Primary
Concomitant
Nasopharyngitis 12/1/2008 Female 3/12/2009 Consumer United States
Primary
Concomitant
Tremor 1/1/1981 Male 3/12/2009 Consumer United States
Primary
Secondary
Concomitant
Psychotic Behaviour Hospitalization 53 Male 3/6/2009 Consumer United States
Primary
Concomitant
Convulsion Other Serious 3/17/2009 42 Male 230 lb 3/26/2009 Consumer United States
Primary
Secondary
Concomitant
Temperature Intolerance Hospitalization 1/16/1998 30 Female 228 lb 4/3/2009 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/1/2000 43 Female 239 lb 4/17/2009 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Death Male 4/24/2009 Lawyer United States
Primary
Concomitant
Product Substitution Issue Other Serious Female 60 lb 5/4/2009 United States
Primary
Secondary
Toxic Epidermal Necrolysis Death Male 5/5/2009 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/8/2004 39 Male 340 lb 5/18/2009 United States
Primary
Concomitant
Eye Movement Disorder Other Serious 3/27/2009 55 Male 225 lb 6/10/2009 Lawyer United States
Primary
Concomitant
Epilepsy Hospitalization 12/29/2008 Female 151 lb 6/17/2009 Pharmacist United States
Primary
Concomitant
Somnolence 3/1/2009 Female 6/12/2009 Consumer United States
Primary
Concomitant
Overdose Other Serious 12/15/2006 Male 142 lb 7/6/2009 Physician United States
Primary
Concomitant
Premature Baby Other Serious 5/1/2008 Male 8 lb 6/30/2009 Physician United States
Primary
Concomitant
Product Substitution Issue Other Serious 6/1/2009 Male 7/2/2009 Physician United States
Primary
Secondary
Oedema Mouth 4/16/2009 60 Female 7/10/2009 Consumer United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 5/26/2009 34 Female 7/9/2009 Italy
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 1/1/2008 46 Female 7/20/2009 Physician United States
Primary
Concomitant
Suicide Attempt Other Serious 1/1/1993 22 144 lb 7/22/2009 United States
Primary
Secondary
Concomitant
Incorrect Dose Administered 7/1/2009 Male 7/15/2009 Pharmacist United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 1/1/2008 46 Female 7/24/2009 Other Health Professional United States
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 10/14/2008 Male 7/27/2009 Physician United States
Primary
Secondary
Concomitant
Product Substitution Issue Hospitalization 4/1/2009 3 Female 29 lb 7/22/2009 Consumer United States
Primary
Secondary
Concomitant
Treatment Failure 7/21/2009 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 7/12/2009 40 Male 7/27/2009 Physician Spain
Primary
Concomitant
Pollakiuria Hospitalization 7/20/2009 Male 224 lb 7/23/2009 Other Health Professional United States
Primary
Concomitant
Treatment Noncompliance Life Threatening 6/1/2009 60 Male 183 lb 7/27/2009 Consumer United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 5/26/2009 34 Female 7/28/2009 Italy
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 1/1/2008 46 Female 8/12/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 15 Male 113 lb 8/5/2009 United States
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 1/1/2008 46 Female 8/18/2009 Other Health Professional United States
Primary
Concomitant
Psychotic Disorder Hospitalization 53 Male 8/13/2009 Physician United States
Primary
Concomitant
Respiratory Depression Other Serious 1/1/2008 46 Female 9/2/2009 Other Health Professional United States
Primary
Concomitant
Convulsion Other Serious 9/2/2009 Other Health Professional United States
Primary
Concomitant

Drug Data