Depakote combined with Folic Acid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sepsis Death Male 1/26/2006 United States
Primary
Secondary
Concomitant
Upper Limb Fracture Other Serious 2/5/2006 Male 230 lb 3/1/2006 United States
Primary
Secondary
Concomitant
Rash Other Serious 10/19/2005 25 Male 1/20/2006 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Other Serious 10/1/2003 60 Male 2/21/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 2/28/2006 61 Male 5/12/2006 Other Health Professional France
Primary
Concomitant
Interacting
Death Death 11/15/2005 63 Male 256 lb 2/20/2006 Physician United States
Primary
Concomitant
Drug Exposure Before Pregnancy Other Serious 2/16/2004 36 Female 6/26/2006 Other Health Professional United States
Primary
Concomitant
Vomiting 44 Male 7/21/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/6/2005 50 Male 201 lb 3/7/2006 Consumer United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2003 79 Female 154 lb 8/1/2006 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Male 8/8/2006 Other Health Professional United States
Primary
Concomitant
Vision Blurred Hospitalization 7/15/2006 51 Female 209 lb 8/31/2006 Physician France
Primary
Concomitant
Somnolence Other Serious 8/8/2006 Female 150 lb 9/21/2006 Consumer United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 12/1/2001 Female 134 lb 9/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 12/1/2001 Female 134 lb 10/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 7/15/2006 51 Female 209 lb 10/23/2006 Physician France
Primary
Concomitant
Suicidal Ideation Other Serious 12/1/2001 Female 134 lb 11/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pancytopenia Required Intervention 11/14/2006 60 Male 201 lb 11/22/2006 Pharmacist United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 40 Female 12/13/2006 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 12/1/2001 Female 134 lb 12/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged 7/20/2006 56 Female 196 lb 7/28/2006 Pharmacist United States
Primary
Concomitant
Vomiting Required Intervention 1/10/2007 Female 134 lb 1/17/2007 Pharmacist United States
Primary
Concomitant
Suicidal Ideation Other Serious 12/1/2001 Female 134 lb 2/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor 1/1/2006 37 Female 2/28/2007 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 12/26/2006 Male 110 lb 3/1/2007 Other Health Professional United States
Primary
Concomitant
Spina Bifida Congenital Anomaly 2/2/2007 3/9/2007 Consumer United States
Primary
Secondary
Concomitant
Extrapyramidal Disorder 2/1/2007 Female 4/24/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/21/2006 62 Female 122 lb 1/18/2007 Physician United States
Primary
Concomitant
Talipes Congenital Anomaly Male 6/18/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 45 Male 136 lb 6/20/2007 Physician United States
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Death 15 Male 77 lb 6/27/2007 Consumer United States
Primary
Secondary
Concomitant
Intra-uterine Death Death 5/9/2007 20 Female 7/19/2007 United States
Primary
Secondary
Concomitant
Intra-uterine Death Other Serious 5/9/2007 20 Female 7/11/2007 Consumer United States
Primary
Secondary
Concomitant
Talipes Congenital Anomaly Male 7/25/2007 Other Health Professional United States
Primary
Concomitant
Abortion Spontaneous Other Serious 3/4/2007 30 Female 7/26/2007 United States
Primary
Secondary
Concomitant
Injection Site Reaction Other Serious 12/1/2006 19 Female 95 lb 7/9/2007 Other Health Professional United States
Primary
Concomitant
Intra-uterine Death Death 5/9/2007 20 Female 8/15/2007 United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 5/7/2007 49 Male 157 lb 9/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hemianopia Homonymous Other Serious 4/17/2007 Female 9/11/2007 Physician United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Death 1/1/2004 15 Male 77 lb 9/26/2007 Consumer United States
Primary
Secondary
Concomitant
Ureteral Disorder Congenital Anomaly Male 10/16/2007 Consumer United States
Primary
Concomitant
Ectopic Pregnancy Other Serious 12/23/1999 30 Female 10/24/2007 United States
Primary
Secondary
Concomitant
Meningitis Hospitalization 1/1/2007 Female 160 lb 10/1/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 Male 186 lb 11/8/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 8/8/2007 22 Female 1/16/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 8/8/2007 Female 2/1/2008 Consumer United States
Primary
Secondary
Concomitant
Parkinsonian Rest Tremor Other Serious 7/16/1990 64 Male 165 lb 3/4/2008 Physician Brazil
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 9/15/2007 84 Female 3/4/2008 Pharmacist United States
Primary
Secondary
Concomitant
Parkinsonian Rest Tremor Other Serious 7/16/1990 64 Male 165 lb 3/7/2008 Physician Brazil
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 7/16/1990 64 Male 165 lb 3/11/2008 Physician Brazil
Primary
Secondary
Concomitant
Hepatic Failure Death Female 3/20/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 84 lb 3/21/2008 Consumer United States
Primary
Concomitant
Hypertension 12/12/2007 70 Male 2/4/2008 United States
Primary
Concomitant
Hepatic Failure Death Female 4/1/2008 Physician United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 15 Male 77 lb 4/29/2008 Lawyer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 15 Male 77 lb 5/5/2008 Lawyer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 5/6/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2006 Female 139 lb 5/27/2008 United States
Primary
Secondary
Concomitant
Ectopic Pregnancy Other Serious 12/23/1998 30 Female 6/6/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 139 lb 6/12/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2005 Female 94 lb 6/12/2008 Consumer United States
Primary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/19/2008 Lawyer United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/23/2008 Lawyer United States
Primary
Secondary
Concomitant
Hypertension 12/12/2007 70 Male 5/6/2008 United States
Primary
Concomitant
Insomnia Hospitalization 58 Female 7/25/2008 Consumer United States
Primary
Secondary
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 8/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 4/20/2008 66 Male 7/7/2008 Pharmacist United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 8/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Hospitalization 1/1/2008 Female 282 lb 9/8/2008 Physician France
Primary
Secondary
Concomitant
Myocardial Infarction Death Male 9/29/2008 Pharmacist United States
Primary
Concomitant
Osteoarthritis 62 Female 228 lb 10/7/2008 Consumer United States
Primary
Concomitant
Pulmonary Arterial Hypertension Congenital Anomaly 11/4/2001 Male 10/8/2008 Consumer United States
Primary
Secondary
Concomitant
Heart Disease Congenital Other Serious 10/13/2008 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Arterial Hypertension Congenital Anomaly 11/4/2001 Male 10/20/2008 Consumer United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 8/5/2008 22 Female 221 lb 11/4/2008 Pharmacist United States
Primary
Concomitant
Vomiting Disability 10/4/2008 32 Female 158 lb 12/1/2008 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Death 11/21/2008 88 Male 148 lb 12/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Death 11/21/2008 88 Male 148 lb 12/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Premature Baby Other Serious 5/1/2008 Male 8 lb 2/23/2009 Physician United States
Primary
Concomitant
Premature Labour Hospitalization 5/1/2008 31 Female 2/23/2009 Physician United States
Primary
Concomitant
Premature Baby Other Serious 5/1/2008 Male 8 lb 2/23/2009 Physician United States
Primary
Concomitant
Grand Mal Convulsion Hospitalization 5/1/2008 31 Female 2/23/2009 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious 11/1/2008 Female 150 lb 3/5/2009 Consumer United States
Primary
Concomitant
Mastication Disorder Male 130 lb 3/12/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2007 Female 108 lb 3/12/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 8/9/2005 49 Female 193 lb 4/17/2009 United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 1/1/2003 36 Male 210 lb 4/21/2009 United States
Primary
Concomitant
Vomiting Hospitalization 4/1/2009 Female 117 lb 4/24/2009 Physician Brazil
Primary
Concomitant
Thrombocytopenia Other Serious 2/8/2001 43 Male 240 lb 5/20/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/1997 23 Male 150 lb 5/21/2009 United States
Primary
Concomitant
Insomnia Hospitalization 58 Female 5/29/2009 Consumer United States
Primary
Secondary
Road Traffic Accident Other Serious 1/1/2005 Female 6/22/2009 Lawyer United States
Primary
Secondary
Concomitant
Haematuria Other Serious 6/1/2009 Male 7/2/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 3/15/2009 52 Male 137 lb 7/3/2009 Physician United States
Primary
Secondary
Concomitant
Premature Baby Other Serious 5/1/2008 Male 8 lb 6/30/2009 Physician United States
Primary
Concomitant
Pancreatitis Acute Other Serious 1/1/2004 46 Male 148 lb 7/10/2009 United States
Primary
Concomitant
Sleep Disorder Other Serious 6/27/2009 Male 206 lb 7/14/2009 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/21/2002 44 Female 144 lb 7/16/2009 United States
Primary
Concomitant
Hypoglycaemia Other Serious 11/20/2001 51 Male 165 lb 7/21/2009 United States
Primary
Concomitant
Weight Increased Other Serious 6/13/2003 42 Female 175 lb 7/21/2009 United States
Primary
Concomitant
Cardiac Failure Congestive Death Female 7/22/2009 Consumer United States
Primary
Concomitant
Hypoglycaemic Encephalopathy Other Serious 1/1/2002 39 Female 196 lb 7/22/2009 United States
Primary
Concomitant
Pancreatitis Chronic Other Serious 9/20/2006 32 Female 132 lb 7/23/2009 United States
Primary
Secondary
Concomitant
Haematuria Other Serious 6/1/2009 Male 7/27/2009 Other Health Professional United States
Primary
Concomitant
Grand Mal Convulsion Life Threatening 7/19/2009 Female 197 lb 7/28/2009 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 6/15/1998 36 Male 208 lb 7/28/2009 United States
Primary
Secondary
Concomitant
Wound Other Serious 1/1/2004 8/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Disability 3/19/2009 Female 8/6/2009 United States
Primary
Concomitant
Cardiac Failure Congestive Death Female 8/11/2009 Consumer United States
Primary
Concomitant
Wound Sepsis Hospitalization 53 Male 8/12/2009 Other Health Professional United States
Primary
Concomitant
Tongue Injury Other Serious 7/1/2009 Male 8/14/2009 Consumer United States
Primary
Concomitant
Nervousness Other Serious 6/27/2009 Male 206 lb 9/2/2009 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy Congenital Anomaly 1/29/1996 Female 9/8/2009 Other Health Professional United States
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 1/29/1996 Female 9/10/2009 Other Health Professional United States
Primary
Concomitant
Vesicoureteric Reflux Congenital Anomaly 1/29/1996 Female 9/15/2009 Other Health Professional United States
Primary
Concomitant
Convulsion 7/1/2009 Female 155 lb 9/15/2009 Physician United States
Primary
Secondary
Concomitant
Diabetic Coma Other Serious 5/6/2007 52 Female 122 lb 9/23/2009 United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 12/8/2002 33 Female 172 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/1/2004 51 Female 166 lb 9/23/2009 United States
Primary
Concomitant
Grand Mal Convulsion Hospitalization 7/19/2009 Female 197 lb 9/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Disorder Other Serious 9/14/2009 44 Female 200 lb 10/6/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 3/19/2009 Female 10/22/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 3/19/2009 Female 11/3/2009 United States
Primary
Concomitant
Vomiting Hospitalization 74 Female 164 lb 10/26/2009 United States
Primary
Concomitant
Vertigo Hospitalization 74 Female 164 lb 10/30/2009 United States
Primary
Concomitant
Road Traffic Accident Other Serious 1/1/2005 49 Female 11/9/2009 Lawyer United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 74 Female 164 lb 11/17/2009 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 Male 186 lb 11/30/2009 Physician United States
Primary
Concomitant
Hepatic Failure Death Female 12/1/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 4/1/2009 Female 117 lb 12/1/2009 Physician Brazil
Primary
Concomitant
Urethral Fistula Congenital Anomaly Male 12/8/2009 Other Health Professional United States
Primary
Concomitant
Road Traffic Accident Other Serious 1/1/2005 49 Female 12/9/2009 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 74 Female 164 lb 12/2/2009 United States
Primary
Concomitant
Hepatic Enzyme Increased 11/7/2008 75 Female 12/9/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 10/30/2009 Male 178 lb 12/18/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2005 49 Female 1/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 74 Female 164 lb 1/8/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 74 Female 164 lb 1/20/2010 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2005 Male 980 lb 2/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2005 49 Female 2/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Premature Baby Other Serious 11/28/2008 Male 8 lb 2/3/2010 Physician United States
Primary
Concomitant
Premature Baby Other Serious 11/28/2008 Male 8 lb 2/8/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2005 Male 980 lb 2/23/2010 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2005 49 Female 2/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 8/14/2009 30 Female 2/26/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2005 Male 980 lb 3/1/2010 Pharmacist United States
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 10/1/2006 Female 118 lb 3/2/2010 Physician United States
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 10/2/2009 48 Female 132 lb 3/9/2010 Other Health Professional United States
Primary
Concomitant
Skin Lesion 1/1/2001 Female 143 lb 3/15/2010 Physician United States
Primary
Concomitant
Blood Sodium Increased Male 3/15/2010 Pharmacist United States
Primary
Secondary
Concomitant

Drug Data