Depakene combined with Topiramate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Chronic Lymphocytic Leukaemia Disability 1/1/2001 37 Male 1/5/2006 France
Primary
Concomitant
Tachycardia Disability 11 Male 4/20/2006 Other Health Professional France
Primary
Concomitant
Pharyngotonsillitis Hospitalization 2/15/2006 Male 4/21/2006 Other Health Professional France
Primary
Secondary
Upper Respiratory Tract Infection Hospitalization 3/23/2006 Male 5/22/2006 Other Health Professional France
Primary
Secondary
Hyperammonaemia Life Threatening 4/23/2006 Female 5/31/2006 Other Health Professional France
Primary
Concomitant
Interacting
Somnolence Hospitalization 5/1/2006 12 Female 6/23/2006 Physician France
Primary
Concomitant
Abortion Spontaneous Other Serious 2/1/2006 36 Female 9/15/2006 Other Health Professional France
Primary
Concomitant
Somnolence Other Serious 5/8/2006 25 Female 9/28/2006 Consumer France
Primary
Concomitant
Status Epilepticus Other Serious 10/19/2006 Male 12/15/2006 Other Health Professional France
Primary
Concomitant
Oedema Peripheral Hospitalization Male 176 lb 12/21/2006 Consumer Brazil
Primary
Concomitant
Thrombocytopenia Hospitalization 12/13/2006 Male 1/24/2007 Physician France
Primary
Concomitant
Pharyngotonsillitis Hospitalization 2/15/2006 Male 2/2/2007 Other Health Professional France
Primary
Secondary
Upper Respiratory Tract Infection Hospitalization 3/23/2006 Male 2/2/2007 Other Health Professional France
Primary
Secondary
Platelet Count Decreased Other Serious 7 Male 44 lb 4/3/2007 Consumer Brazil
Primary
Concomitant
Respiratory Tract Congestion Other Serious 7 Male 44 lb 5/1/2007 Consumer Brazil
Primary
Concomitant
Somnolence Hospitalization 2/5/2007 Female 20 lb 5/25/2007 Physician Netherlands
Primary
Concomitant
Thrombocytopenia Hospitalization 3/12/2007 14 Female 6/9/2007 Other Health Professional France
Primary
Concomitant
Somnolence Hospitalization 2/5/2007 Female 20 lb 6/19/2007 Physician Netherlands
Primary
Concomitant
Thrombocytopenia Other Serious 3/28/2007 52 Female 12/3/2007 Other Health Professional France
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2005 20 Male 154 lb 1/3/2008 Physician France
Primary
Secondary
Concomitant
Single Umbilical Artery Congenital Anomaly Female 2/1/2008 Other Health Professional France
Primary
Secondary
Premature Baby Other Serious 1/1/2005 0 Male 2/1/2008 Other Health Professional France
Primary
Secondary
Pyrexia Other Serious 1 Male 2/7/2008 France
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 2/19/2008 4 Female 2/28/2008 Other Health Professional Japan
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 12/7/2007 2/29/2008 Consumer France
Primary
Secondary
Varicella Hospitalization 12/20/2006 Female 17 lb 3/19/2008 Physician Ukraine
Primary
Concomitant
Epilepsy Other Serious 12/15/2007 29 Male 3/28/2008 Other Health Professional France
Primary
Concomitant
Interacting
Ventricular Septal Defect Congenital Anomaly 6/9/2006 Female 4/4/2008 Other Health Professional France
Primary
Secondary
Tachycardia Other Serious 1/30/2008 Female 4/4/2008 Other Health Professional France
Primary
Secondary
Concomitant
Tonic Clonic Movements Other Serious 8/2/2007 Male 4/25/2008 Other Health Professional France
Primary
Secondary
Learning Disability Other Serious 1/1/2004 Female 5/1/2008 Consumer Barbados
Primary
Concomitant
Tremor Other Serious 1/1/2004 Female 53 lb 5/22/2008 Physician Barbados
Primary
Concomitant
Nephrolithiasis Hospitalization 5/8/2008 Male 7/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 4/30/2008 Male 8/27/2008 Other Health Professional France
Primary
Concomitant
Headache Other Serious 9/4/2008 Male 198 lb 9/16/2008 Consumer Brazil
Primary
Secondary
Lack Of Spontaneous Speech Other Serious 5/1/2008 Female 29 lb 9/29/2008 Pharmacist France
Primary
Concomitant
Tachypnoea Life Threatening 9/3/2008 Female 10/9/2008 Other Health Professional France
Primary
Concomitant
Memory Impairment Congenital Anomaly Male 10/16/2008 Consumer France
Primary
Concomitant
Tachypnoea Life Threatening 9/3/2008 Female 10/29/2008 Other Health Professional France
Primary
Concomitant
Renal Impairment Hospitalization 3/15/2008 42 Female 1/23/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 Female 2/4/2009 Consumer Brazil
Primary
Concomitant
Medication Residue Life Threatening 10 Male 4/3/2009 Physician France
Primary
Concomitant
Renal Failure Hospitalization 4/14/2009 Male 77 lb 5/6/2009 Physician Brazil
Primary
Concomitant
Status Epilepticus Other Serious 4/14/2009 12 Male 62 lb 5/18/2009 Physician Japan
Primary
Concomitant
Status Epilepticus Other Serious 4/14/2009 12 Male 62 lb 5/27/2009 Physician Japan
Primary
Concomitant
Renal Failure Hospitalization 4/14/2009 Male 77 lb 6/3/2009 Physician Brazil
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 4/1/2009 Female 6/26/2009 Physician Japan
Primary
Concomitant
Medication Residue Life Threatening 10 Male 9/24/2009 Physician France
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 4/1/2009 Female 10/7/2009 Physician Japan
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 7/2/2009 Male 10/7/2009 Pharmacist Japan
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 7/2/2009 Male 10/26/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Tremor Hospitalization 2/1/2006 29 Male 185 lb 10/30/2009 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 4/1/2009 Female 11/23/2009 Physician Japan
Primary
Concomitant
Convulsion Other Serious 11/24/2009 23 Male 95 lb 12/16/2009 Pharmacist Japan
Primary
Concomitant
Hallucination, Visual Other Serious 8/5/2009 30 Male 117 lb 1/4/2010 Japan
Primary
Secondary
Concomitant
Memory Impairment Other Serious 8/5/2009 30 Male 117 lb 3/25/2010 Japan
Primary
Concomitant
Interacting
Toxic Epidermal Necrolysis Life Threatening 5/1/2009 48 Male 4/5/2010 Physician Japan
Primary
Concomitant
Injury Other Serious Male 4/8/2010 Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 10/23/2009 54 Male 4/12/2010 Other Health Professional Japan
Primary
Concomitant
Suicidal Ideation Life Threatening 3/9/2010 70 Male 5/25/2010 Other Health Professional Japan
Primary
Concomitant
Vomiting Hospitalization 4/1/2010 84 Female 6/9/2010 Other Health Professional France
Primary
Secondary
Concomitant
Nervous System Disorder Hospitalization 4/16/2010 58 Male 6/10/2010 Consumer France
Primary
Secondary
Concomitant
Hyperammonaemia Hospitalization 4/16/2010 58 Male 6/14/2010 Other Health Professional France
Primary
Secondary
Death Hospitalization 3/1/2010 88 Male 6/15/2010 Other Health Professional Japan
Primary
Concomitant
Off Label Use Hospitalization 1/1/2010 58 Male 6/18/2010 Consumer France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 4/1/2009 14 Female 6/25/2010 Physician Japan
Primary
Concomitant
Status Epilepticus Hospitalization 3/18/2009 7 Female 7/2/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 10/23/2009 54 Male 7/6/2010 Other Health Professional Japan
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 7/15/2010 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/6/2009 9 Male 8/2/2010 Physician Japan
Primary
Concomitant
Hyperlipasaemia Hospitalization 7/7/2010 19 Female 8/2/2010 Physician France
Primary
Secondary
Concomitant
Hyperlipasaemia Hospitalization 7/7/2010 19 Female 8/3/2010 Physician France
Primary
Secondary
Concomitant
Tremor Hospitalization 2/1/2006 29 Male 187 lb 8/5/2010 France
Primary
Secondary
Concomitant
Bradyphrenia Hospitalization 6/6/2009 9 Male 8/19/2010 Physician Japan
Primary
Concomitant
Condition Aggravated Hospitalization 3/29/2010 7 Female 49 lb 9/15/2010 Physician France
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 3/29/2010 7 Female 49 lb 9/23/2010 Other Health Professional France
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 4/1/2010 1 Male 18 lb 9/28/2010 Physician China
Primary
Secondary
Renal Failure Acute Hospitalization 10/12/2010 63 Male 88 lb 10/25/2010 Other Health Professional Japan
Primary
Concomitant
Syncope Other Serious 1/1/2008 16 Female 11/4/2010 Consumer Brazil
Primary
Concomitant
Joint Dislocation Other Serious 6/16/2010 12 Male 44 lb 11/16/2010 Physician Japan
Primary
Concomitant
Encephalitis Herpes Hospitalization 9/15/2010 14 Male 150 lb 12/6/2010 Physician Japan
Primary
Concomitant
Encephalitis Herpes Hospitalization 9/15/2010 14 Male 150 lb 12/13/2010 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 10/12/2010 63 Male 88 lb 12/15/2010 Physician Japan
Primary
Concomitant
Hyperammonaemia Hospitalization 79 Male 12/17/2010 Other Health Professional Japan
Primary
Secondary
Weight Increased Other Serious 23 Female 110 lb 12/21/2010 Physician Denmark
Primary
Secondary
Weight Decreased Hospitalization 12/22/2010 26 Male 110 lb 1/17/2011 Other Health Professional Japan
Primary
Concomitant
Hyperammonaemic Encephalopathy Hospitalization 7/17/2010 79 Male 1/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Fatigue Hospitalization 10/12/2010 63 Male 88 lb 2/11/2011 Physician Japan
Primary
Concomitant
Depression Other Serious Female 2/16/2011 Consumer France
Primary
Concomitant
Interacting
Status Epilepticus Hospitalization 6/1/2009 3 Female 2/28/2011 Physician Japan
Primary
Concomitant
Status Epilepticus Hospitalization Female 3/2/2011 Physician Japan
Primary
Concomitant
Bradykinesia Hospitalization 6/6/2009 9 Male 3/11/2011 Physician Japan
Primary
Concomitant
Fracture Other Serious 4 3/25/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Fracture Other Serious 4 3/30/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Fanconi Syndrome Acquired Other Serious 9/21/2010 Male 4/14/2011 Physician Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/1/2010 59 Male 4/25/2011 Other Health Professional Japan
Primary
Concomitant
Epilepsy Other Serious 4/6/2011 40 Male 5/9/2011 Other Health Professional Japan
Primary
Concomitant
Postictal Psychosis Other Serious 4/10/2011 30 Male 5/16/2011 Physician Japan
Primary
Concomitant
Sensory Disturbance Other Serious Female 5/20/2011 Consumer France
Primary
Secondary
Concomitant
Epilepsy Other Serious 4/17/2011 40 Male 5/20/2011 Other Health Professional Japan
Primary
Concomitant
Tracheostomy Other Serious 9/21/2008 16 Female 5/27/2011 Consumer United States
Primary
Secondary
Concomitant
Irritability Hospitalization 9/1/2010 13 Male 6/14/2011 Other Health Professional France
Primary
Secondary
Concomitant
Hallucination, Auditory Hospitalization 15 Male 6/17/2011 Other Health Professional Japan
Primary
Secondary
Drug Ineffective For Unapproved Indication Other Serious 5/28/2011 20 Female 29 lb 6/17/2011 Physician Japan
Primary
Concomitant
Headache Hospitalization 6/1/2011 15 Male 7/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hyperthyroidism Other Serious 13 Female 7/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Headache Hospitalization 6/1/2011 15 Male 7/15/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 13 Female 7/18/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 5/2/2011 9 8/17/2011 Physician Taiwan, Province Of China
Primary
Concomitant
Oculomucocutaneous Syndrome Hospitalization 51 Female 8/19/2011 Physician Japan
Primary
Concomitant
Delirium Other Serious 1/1/2011 Male 8/23/2011 Physician Japan
Primary
Concomitant
Status Epilepticus Hospitalization Female 8/26/2011 Physician Japan
Primary
Concomitant
Band Neutrophil Percentage Increased Hospitalization 8/4/2011 51 Female 9/2/2011 Physician Japan
Primary
Concomitant
Haematocrit Increased Hospitalization 8/4/2011 51 Female 9/19/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 8/4/2011 51 Female 9/23/2011 Physician Japan
Primary
Concomitant
Chorea Hospitalization 8/1/2011 13 Male 72 lb 9/30/2011 Other Health Professional Japan
Primary
Concomitant
Mucosal Erosion Hospitalization 8/4/2011 51 Female 10/5/2011 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 9/12/2011 32 Female 10/12/2011 Other Health Professional Japan
Primary
Concomitant
Disorientation Hospitalization 8/1/2011 51 Male 10/14/2011 Other Health Professional Japan
Primary
Secondary
Osteopenia Other Serious 2/1/2006 29 Male 187 lb 10/18/2011 Physician France
Primary
Secondary
Concomitant
Maternal Exposure During Pregnancy Congenital Anomaly 3/12/2011 Male 10/27/2011 Other Health Professional France
Primary
Secondary
Concomitant
Maternal Exposure During Pregnancy Other Serious 1/1/2008 17 Female 10/28/2011 Other Health Professional France
Primary
Secondary
Ventricular Septal Defect Congenital Anomaly 1/1/2008 3 Female 10/31/2011 Other Health Professional France
Primary
Secondary
Hypospadias Congenital Anomaly 3/12/2011 Male 6 lb 10/31/2011 Other Health Professional France
Primary
Secondary
Chorea Hospitalization 8/1/2011 13 Male 72 lb 11/4/2011 Other Health Professional Japan
Primary
Concomitant
Chorea Hospitalization 8/1/2011 13 Male 72 lb 11/4/2011 Other Health Professional Japan
Primary
Concomitant
Gastrointestinal Necrosis Death 10/29/2011 54 Female 152 lb 11/7/2011 Physician Greece
Primary
Secondary
Concomitant
Somnolence Hospitalization 8/1/2011 51 Male 11/10/2011 Other Health Professional Japan
Primary
Secondary
Photophobia Disability 1/1/2005 20 Male 154 lb 11/15/2011 Physician France
Primary
Secondary
Concomitant
Irritability Hospitalization 9/1/2010 13 Male 11/22/2011 Physician France
Primary
Secondary
Concomitant
Drug Level Below Therapeutic Other Serious 4/19/2011 1 Female 11/29/2011 Other Health Professional Portugal
Primary
Concomitant
Rash Hospitalization 11/17/2011 41 Female 12/28/2011 Physician Japan
Primary
Concomitant
Blood Immunoglobulin G Decreased Hospitalization 4/1/2009 14 Female 1/4/2012 Physician Japan
Primary
Concomitant
Encephalopathy Hospitalization 8/5/2011 18 Male 1/5/2012 Other Health Professional France
Primary
Secondary
Concomitant
Encephalopathy Hospitalization 8/5/2011 18 Male 1/6/2012 Physician France
Primary
Secondary
Concomitant
Maternal Exposure During Pregnancy Other Serious 12/18/2011 24 Female 2/3/2012 Consumer Japan
Primary
Concomitant
Cleft Palate Other Serious 12/18/2011 0 Male 2/7/2012 Consumer Japan
Primary
Concomitant
Maternal Exposure During Pregnancy Other Serious Female 2/7/2012 Physician Japan
Primary
Concomitant
Hypotension Other Serious 12/1/2011 43 Male 141 lb 2/14/2012 Physician Japan
Primary
Concomitant
C-reactive Protein Increased Other Serious 1/8/2012 8 Male 2/15/2012 Physician Japan
Primary
Secondary
Disorientation Hospitalization 8/1/2011 51 Male 2/17/2012 Other Health Professional Japan
Primary
Secondary
Polyhydramnios Hospitalization Female 2/21/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Ileus Hospitalization 1/21/2011 68 Male 3/2/2012 Other Health Professional Japan
Primary
Concomitant
Hypernatraemia Hospitalization 1/21/2011 68 Male 3/20/2012 Other Health Professional Japan
Primary
Concomitant
Somnolence Hospitalization 8/1/2011 51 Male 3/20/2012 Other Health Professional Japan
Primary
Secondary
Ammonia Increased Other Serious 1/14/2012 4 Male 44 lb 3/20/2012 Consumer Brazil
Primary
Concomitant
Ammonia Increased Other Serious 1/14/2012 4 Male 44 lb 3/29/2012 Consumer Brazil
Primary
Concomitant
Drug Ineffective Other Serious 1/14/2012 4 Male 44 lb 4/3/2012 Consumer Brazil
Primary
Concomitant
Drug Interaction Other Serious 1/1/2011 17 Female 5/4/2012 Consumer France
Primary
Concomitant
Interacting
Joint Dislocation Other Serious 6/16/2010 12 Male 44 lb 5/9/2012 Physician Japan
Primary
Concomitant

Drug Data