Denosumab combined with Vitamin D

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Localised Oedema Hospitalization 5/11/2010 92 Male 6/9/2010 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 4/13/2010 78 Female 6/11/2010 Physician Argentina
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 4/13/2010 78 Female 6/28/2010 Physician Argentina
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 4/13/2010 78 Female 7/6/2010 Physician Argentina
Primary
Concomitant
Osteomyelitis Hospitalization 2/8/2010 57 Female 119 lb 7/9/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 7/31/2007 45 Female 7/27/2010 Physician India
Primary
Secondary
Concomitant
Mycobacterium Avium Complex Infection Other Serious 2/16/2010 77 Female 8/12/2010 Physician United States
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 7/12/2010 68 Male 8/13/2010 Physician
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 7/12/2010 68 Male 8/20/2010 Physician
Primary
Concomitant
Osteomyelitis Hospitalization 2/8/2010 57 Female 117 lb 8/23/2010 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 8/17/2010 68 Female 9/7/2010 Physician United States
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 7/12/2010 68 Male 10/5/2010 Physician
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 8/17/2010 68 Female 10/7/2010 Physician United States
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 5/6/2009 55 Male 183 lb 10/13/2010 Physician Hungary
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 8/17/2010 68 Female 3/31/2011 Physician United States
Primary
Concomitant
Spinal Compression Fracture Hospitalization 4/11/2011 74 Female 5/23/2011 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 10/7/2009 82 Male 202 lb 5/25/2011 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 10/31/2010 83 Male 198 lb 5/26/2011 Physician United States
Primary
Concomitant
Spinal Compression Fracture Disability 4/11/2011 74 Female 5/30/2011 Physician United States
Primary
Concomitant
Spinal Compression Fracture Disability 4/11/2011 74 Female 6/10/2011 Physician United States
Primary
Concomitant
Pain In Jaw Other Serious 5/1/2010 140 lb 6/13/2011 Physician Russian Federation
Primary
Concomitant
Gastric Ulcer Hospitalization 1/13/2011 79 Female 6/29/2011 Physician Denmark
Primary
Concomitant
Cerebrovascular Accident Hospitalization 10/31/2010 83 Male 198 lb 6/30/2011 Physician United States
Primary
Concomitant
Vasculitis Disability 11/16/2010 59 Female 7/1/2011 Physician Netherlands
Primary
Concomitant
Gastric Ulcer Hospitalization 1/13/2011 79 Female 7/11/2011 Physician Denmark
Primary
Concomitant
Gastric Ulcer Hospitalization 1/13/2011 79 Female 7/15/2011 Physician Denmark
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 6/13/2011 81 Female 7/19/2011 Other Health Professional Brazil
Primary
Concomitant
Vasculitis Disability 11/16/2010 59 Female 7/20/2011 Physician Netherlands
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 4/11/2011 74 Female 8/4/2011 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/30/2011 50 Female 8/4/2011 Physician Canada
Primary
Concomitant
Pain In Jaw Other Serious 2/18/2011 72 Male 8/5/2011 Physician Finland
Primary
Concomitant
Tooth Fracture Other Serious 1/23/2009 65 Male 8/8/2011 Physician New Zealand
Primary
Concomitant
Hallucination Hospitalization 6/1/2011 85 Male 185 lb 8/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/30/2011 50 Female 8/18/2011 Physician Canada
Primary
Concomitant
Thoracic Vertebral Fracture Disability 4/11/2011 74 Female 9/1/2011 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/30/2011 50 Female 9/2/2011 Physician Canada
Primary
Concomitant
Osteoarthritis Hospitalization 4/20/2009 75 Female 9/2/2011 Physician Denmark
Primary
Concomitant
Temporal Arteritis Disability 11/16/2010 59 Female 9/8/2011 Physician Netherlands
Primary
Concomitant
Pain In Jaw Other Serious 5/1/2010 140 lb 9/13/2011 Other Health Professional Russian Federation
Primary
Concomitant
Dyspnoea Other Serious 7/1/2011 68 Female 143 lb 9/20/2011 Consumer United States
Primary
Concomitant
Osteonecrosis Other Serious 4/12/2011 82 Female 9/26/2011 Physician Argentina
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/30/2011 50 Female 10/31/2011 Physician Canada
Primary
Concomitant
Uveitis Hospitalization 8/16/2011 77 Male 218 lb 11/3/2011 Physician Australia
Primary
Concomitant
Cerebrovascular Accident Hospitalization 88 Male 11/4/2011 Physician United States
Primary
Secondary
Concomitant
Prostatomegaly Hospitalization 8/19/2011 62 Male 218 lb 11/18/2011 Physician Netherlands
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/30/2011 50 Female 11/22/2011 Physician Canada
Primary
Concomitant
Pain Female 129 lb 11/23/2011 Physician United States
Primary
Secondary
Concomitant
Prostatomegaly Hospitalization 8/19/2011 62 Male 218 lb 11/25/2011 Physician Netherlands
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/30/2011 50 Female 12/7/2011 Physician Canada
Primary
Concomitant
Osteonecrosis Of Jaw Hospitalization 10/22/2011 65 Male 12/9/2011 Physician Poland
Primary
Concomitant
Uveitis Hospitalization 8/16/2011 77 Male 218 lb 12/13/2011 Physician Australia
Primary
Concomitant
Osteonecrosis Other Serious 4/12/2011 82 Female 12/15/2011 Other Health Professional Argentina
Primary
Concomitant
Cerebrovascular Accident Hospitalization 10/31/2010 83 Male 198 lb 12/16/2011 Physician United States
Primary
Concomitant
Uveitis Hospitalization 8/16/2011 77 Male 218 lb 12/19/2011 Physician Australia
Primary
Concomitant
Benign Pancreatic Neoplasm Hospitalization 7/17/2011 77 Female 12/30/2011 Physician Canada
Primary
Concomitant
Osteonecrosis Disability 11/29/2011 75 Male 1/5/2012 Physician France
Primary
Concomitant
Benign Pancreatic Neoplasm Other Serious 77 Female 1/6/2012 Physician Canada
Primary
Concomitant
Osteoarthritis Hospitalization 5/2/2010 71 Female 1/13/2012 Physician Czech Republic
Primary
Concomitant
Osteoarthritis Hospitalization 8/1/2011 80 Female 1/25/2012 Physician Denmark
Primary
Concomitant
Bronchopneumonia Hospitalization 9/14/2011 87 Male 1/26/2012 Physician South Africa
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2004 64 Female 129 lb 1/27/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 1/18/2012 65 Female 2/1/2012 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Of Jaw Disability 11/29/2011 75 Male 2/3/2012 Physician France
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 2/18/2011 72 Male 2/7/2012 Physician Finland
Primary
Concomitant
Optic Nerve Disorder Hospitalization 8/16/2011 77 Male 218 lb 2/10/2012 Physician Australia
Primary
Concomitant
Death Death Male 2/10/2012 Pharmacist United States
Primary
Concomitant
Road Traffic Accident Death 1/18/2012 65 Female 2/14/2012 Other Health Professional United States
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 1/1/2012 69 Female 3/16/2012 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Intervertebral Disc Protrusion Disability 12/31/2011 30 Female 186 lb 4/24/2012 Physician Canada
Primary
Concomitant
Bone Lesion Other Serious 4/27/2011 59 Male 4/27/2012 Physician Brazil
Primary
Concomitant
Femur Fracture Hospitalization 3/23/2012 67 Male 4/27/2012 Physician Canada
Primary
Concomitant
Uveitis Hospitalization 8/16/2011 77 Male 218 lb 5/3/2012 Physician Australia
Primary
Concomitant
Femur Fracture Hospitalization 3/23/2012 67 Male 5/3/2012 Physician Canada
Primary
Concomitant
Neutropenia Hospitalization 3/1/2012 72 Female 176 lb 5/3/2012 Physician Spain
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/30/2011 50 Female 274 lb 5/4/2012 Physician Canada
Primary
Concomitant
Pain In Extremity Hospitalization 9/21/2011 56 Male 5/8/2012 Physician Canada
Primary
Concomitant
Bone Pain Other Serious 12/1/2010 72 Female 5/4/2012 Physician United States
Primary
Secondary
Concomitant
Exposed Bone In Jaw Other Serious 4/27/2011 59 Male 5/9/2012 Physician Brazil
Primary
Concomitant
Psychotic Disorder Hospitalization 4/30/2012 42 Female 172 lb 5/10/2012 Physician Spain
Primary
Concomitant
Pulmonary Embolism Life Threatening 7/30/2011 50 Female 274 lb 5/14/2012 Physician Canada
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/23/2012 80 Male 178 lb 5/15/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Back Pain Hospitalization 4/17/2012 56 Male 5/16/2012 Physician Canada
Primary
Concomitant
Pain In Jaw Hospitalization 12/31/2011 88 Female 5/18/2012 Physician Austria
Primary
Concomitant
Pain In Extremity Hospitalization 3/7/2012 56 Male 5/20/2012 Physician Canada
Primary
Concomitant
Road Traffic Accident Other Serious 1/18/2012 65 Female 5/23/2012 Other Health Professional United States
Primary
Concomitant
Femur Fracture Hospitalization 3/23/2012 67 Male 5/23/2012 Physician Canada
Primary
Concomitant
Fatigue Other Serious 1/1/2012 68 Male 242 lb 5/29/2012 Physician United States
Primary
Secondary
Concomitant
Circulatory Collapse Hospitalization 12/31/2011 88 Female 5/30/2012 Physician Austria
Primary
Concomitant
Psychotic Disorder Hospitalization 4/30/2012 42 Female 172 lb 5/31/2012 Physician Spain
Primary
Concomitant
Pain In Jaw Hospitalization 12/31/2011 88 Female 6/6/2012 Physician Austria
Primary
Concomitant
Cerebral Venous Thrombosis Hospitalization 6/6/2012 44 Female 122 lb 6/14/2012 Physician Canada
Primary
Concomitant
Femur Fracture Hospitalization 11/26/2011 80 Female 6/18/2012 Physician Denmark
Primary
Concomitant
Atypical Femur Fracture Hospitalization 11/26/2011 80 Female 6/26/2012 Physician Denmark
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 2/25/2012 68 Female 148 lb 6/28/2012 Physician France
Primary
Concomitant
Atypical Femur Fracture Hospitalization 11/26/2011 80 Female 6/28/2012 Physician Denmark
Primary
Concomitant
Back Pain Hospitalization 4/17/2012 56 Male 7/2/2012 Physician Canada
Primary
Concomitant
Multiple Allergies 88 Female 7/3/2012 Consumer United States
Primary
Secondary
Concomitant
Spinal Column Stenosis Hospitalization 9/1/2011 77 Female 7/6/2012 Physician Sweden
Primary
Concomitant
Atypical Femur Fracture Hospitalization 11/26/2011 80 Female 7/11/2012 Physician Denmark
Primary
Concomitant
Neutropenia Hospitalization 3/1/2012 72 Female 176 lb 7/12/2012 Physician Spain
Primary
Concomitant
Cerebral Venous Thrombosis Hospitalization 6/6/2012 44 Female 122 lb 7/12/2012 Physician Canada
Primary
Concomitant
Osteoarthritis Hospitalization 5/2/2010 71 Female 7/13/2012 Physician Czech Republic
Primary
Concomitant
Neutropenia Hospitalization 3/1/2012 72 Female 176 lb 7/17/2012 Physician Spain
Primary
Concomitant
Pyelonephritis Acute Hospitalization 6/29/2012 49 Female 182 lb 7/18/2012 Physician United States
Primary
Concomitant
Hyperglycaemia Hospitalization 6/29/2012 49 Female 182 lb 7/18/2012 Physician United States
Primary
Concomitant
Cellulitis Hospitalization 7/14/2012 45 Female 147 lb 7/20/2012 Physician Japan
Primary
Concomitant
Cerebral Venous Thrombosis Hospitalization 6/6/2012 44 Female 122 lb 7/20/2012 Physician Canada
Primary
Concomitant
Nausea Hospitalization 10/20/2011 36 Female 122 lb 7/26/2012 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 9/22/2011 36 Female 122 lb 7/26/2012 Other Health Professional Japan
Primary
Concomitant
Hypocalcaemia Hospitalization 6/23/2012 54 Female 162 lb 7/27/2012 Physician United States
Primary
Concomitant
Vomiting Hospitalization 10/20/2011 36 Female 122 lb 7/30/2012 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 9/22/2011 36 Female 122 lb 7/30/2012 Physician Japan
Primary
Concomitant
Hyperglycaemia Hospitalization 6/29/2012 49 Female 182 lb 7/30/2012 Physician United States
Primary
Concomitant
Cellulitis Hospitalization 7/14/2012 45 Female 147 lb 7/30/2012 Physician Japan
Primary
Concomitant
Neutropenia Hospitalization 3/1/2012 72 Female 176 lb 8/1/2012 Physician Spain
Primary
Concomitant
Viith Nerve Paralysis Other Serious 7/1/2012 55 Female 136 lb 8/2/2012 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 1/4/2012 41 Female 120 lb 8/2/2012 Physician Spain
Primary
Concomitant
Hypocalcaemia Other Serious 6/23/2012 54 Female 162 lb 8/7/2012 Physician United States
Primary
Concomitant
Nausea Hospitalization 10/20/2011 36 Female 122 lb 8/10/2012 Physician Japan
Primary
Concomitant
Metastases To Central Nervous System Other Serious 7/21/2012 55 Female 136 lb 8/13/2012 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/1/2012 87 Female 123 lb 8/14/2012 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/1/2012 87 Female 123 lb 8/24/2012 Physician United States
Primary
Concomitant
Circulatory Collapse Hospitalization 12/31/2011 88 Female 8/27/2012 Physician Austria
Primary
Concomitant
Back Pain Hospitalization 4/17/2012 56 Male 8/27/2012 Physician Canada
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 1/23/2009 65 Male 4/5/2013 Physician Nz
Primary
Concomitant
Osteonecrosis Of Jaw Disability 9/2011 75 Male 4/5/2013 Physician Fr
Primary
Concomitant
Pneumonitis Other Serious 1/23/2012 39 Female 143 lb 1/10/2013 Physician Au
Primary
Concomitant
Neutropenia Hospitalization 3/1/2012 72 Female 176 lb 10/19/2012 Physician Es
Primary
Concomitant
Atypical Femur Fracture Hospitalization 3/23/2012 67 Male 1/7/2013 Physician Ca
Primary
Concomitant
Nausea Hospitalization 1/7/2012 60 Female 150 lb 8/28/2012 Physician Ca
Primary
Secondary
Concomitant
Exposed Bone In Jaw Other Serious 4/27/2011 59 Male 8/30/2012 Physician Br
Primary
Concomitant
Bone Giant Cell Tumour Hospitalization 4/17/2012 56 Male 1/31/2013 Physician Ca
Primary
Concomitant
Psychotic Disorder Hospitalization 4/30/2012 42 Female 172 lb 2/18/2013 Physician Es
Primary
Concomitant
Cerebral Venous Thrombosis Hospitalization 6/6/2012 44 Female 122 lb 4/4/2013 Physician Ca
Primary
Concomitant
Pyelonephritis Acute Hospitalization 7/1/2012 49 Female 182 lb 5/10/2013 Physician Us
Primary
Concomitant
Cellulitis Hospitalization 7/14/2012 45 Female 147 lb 9/6/2012 Physician Jp
Primary
Concomitant
Pyrexia Hospitalization 9/14/2012 61 Female 169 lb 11/6/2012 Physician Nl
Primary
Concomitant
Heart Valve Incompetence Hospitalization 5/10/2012 73 Female 11/19/2012 Physician Dk
Primary
Concomitant
Myocardial Infarction Other Serious 12/2010 54 Female 170 lb 12/13/2012 Other Health Professional Us
Primary
Concomitant
Paraesthesia Oral 9/12/2012 55 Male 229 lb 10/4/2012 Pharmacist Us
Primary
Concomitant
Troponin Increased Hospitalization 8/17/2012 88 Female 12/10/2012 Physician Ca
Primary
Concomitant
Foetal Death Other Serious 11/3/2012 41 Female 159 lb 2/8/2013 Physician Au
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 2/17/2011 72 Female 106 lb 12/11/2012 Physician In
Primary
Concomitant
Urinary Tract Infection 11/2011 74 Female 70 lb 6/6/2013 Physician Us
Primary
Concomitant
Myasthenia Gravis Hospitalization 11/25/2012 89 Female 1/10/2013 Physician Ca
Primary
Concomitant
Osteonecrosis Of Jaw Required Intervention 10/2012 64 Female 201 lb 12/19/2012 Physician Us
Primary
Concomitant
Cholecystitis Acute Hospitalization 12/10/2012 63 Female 211 lb 5/3/2013 Physician Us
Primary
Concomitant
Spinal Compression Fracture Other Serious 2011 74 Female 190 lb 2/28/2013 Consumer Us
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 6/16/2011 90 Male 4/5/2013 Physician Ca
Primary
Concomitant
Osteonecrosis Of Jaw Hospitalization 9/30/2010 79 Male 4/5/2013 Physician Nz
Primary
Concomitant

Drug Data