Darunavir combined with Zidovudine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Hospitalization 12/19/2006 Male 2/6/2007 United States
Primary
Secondary
Concomitant
Status Epilepticus Life Threatening 1/26/2007 58 Female 2/5/2007 Physician France
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 5/25/2004 Male 9/7/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 5/25/2004 Male 11/20/2007 Physician Japan
Primary
Secondary
Concomitant
Micrognathia Congenital Anomaly 10/14/2005 Male 7 lb 2/8/2008 United States
Primary
Secondary
Micrognathia Congenital Anomaly 10/14/2005 Male 2/18/2008 Physician United Kingdom
Primary
Secondary
Micrognathia Congenital Anomaly Male 7 lb 2/6/2008 Other Health Professional United States
Primary
Secondary
Micrognathia Congenital Anomaly 10/14/2005 Male 2/27/2008 Physician United Kingdom
Primary
Secondary
Hypokalaemia Hospitalization 4/9/2008 Male 168 lb 4/28/2008 France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/7/2008 Male 123 lb 5/5/2008 Brazil
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 4/9/2008 48 Male 5/8/2008 France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/7/2008 Male 123 lb 5/12/2008 Brazil
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 4/9/2008 Male 168 lb 5/30/2008 France
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/18/2008 Female 147 lb 5/30/2008 Brazil
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 4/9/2008 48 Male 6/5/2008 France
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/18/2008 Female 147 lb 6/11/2008 Brazil
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/7/2008 Male 123 lb 6/23/2008 Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/18/2008 Female 147 lb 6/27/2008 Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/18/2008 Female 147 lb 7/11/2008 Brazil
Primary
Secondary
Concomitant
Renal Tubular Disorder Other Serious Male 7/30/2008 Consumer Spain
Primary
Secondary
Hypokalaemia Hospitalization 4/9/2008 Male 168 lb 8/1/2008 France
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 4/9/2008 48 Male 8/6/2008 France
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/15/2008 52 Male 130 lb 7/31/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/15/2008 52 Male 130 lb 7/31/2008 Physician United States
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 38 Female 8/29/2008 Denmark
Primary
Secondary
Bicytopenia Death 8/18/2008 Female 138 lb 9/9/2008 Ireland
Primary
Concomitant
Neoplasm Malignant Other Serious 38 Female 9/11/2008 Denmark
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious 22 Male 9/12/2008 Physician United States
Primary
Secondary
Concomitant
Bicytopenia Death 8/18/2008 Female 138 lb 9/16/2008 Ireland
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 22 Male 9/17/2008 United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/29/2006 Male 172 lb 9/18/2008 Ireland
Primary
Concomitant
Pancreatitis Hospitalization 8/26/2008 42 Female 119 lb 9/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Bicytopenia Death 8/18/2008 Female 138 lb 10/3/2008 Ireland
Primary
Concomitant
Vomiting Hospitalization 8/26/2008 42 Female 119 lb 9/29/2008 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/15/2008 52 Male 130 lb 10/1/2008 Physician United States
Primary
Secondary
Concomitant
Urticaria Hospitalization 8/26/2008 42 Female 119 lb 10/3/2008 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/15/2008 52 Male 130 lb 10/6/2008 Physician United States
Primary
Secondary
Concomitant
Bicytopenia Death 8/18/2008 Female 138 lb 10/21/2008 Ireland
Primary
Concomitant
Drug Interaction Other Serious 45 Male 11/19/2008 Other Health Professional United States
Primary
Secondary
Interacting
Drug Interaction Other Serious 45 Male 11/26/2008 Other Health Professional United States
Primary
Secondary
Interacting
Bicytopenia Death 8/18/2008 Female 138 lb 12/10/2008 Ireland
Primary
Concomitant
Bicytopenia Death 8/18/2008 Female 138 lb 12/19/2008 Ireland
Primary
Concomitant
Liver Function Test Abnormal Other Serious 40 Male 1/9/2009
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 5/27/2008 Female 116 lb 1/21/2009 Brazil
Primary
Concomitant
Weight Decreased Hospitalization 9/22/2008 42 Female 1/29/2009 United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 5/27/2008 Female 116 lb 2/11/2009 Brazil
Primary
Concomitant
Varices Oesophageal Life Threatening 5/27/2008 Female 116 lb 2/26/2009 Brazil
Primary
Concomitant
Hypokalaemia Hospitalization 4/9/2008 48 Male 168 lb 3/2/2009 Physician France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 2/10/2009 Male 255 lb 3/4/2009 Physician United States
Primary
Concomitant
Hypokalaemia Hospitalization 4/9/2008 48 Male 168 lb 3/4/2009 Physician France
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 12/26/2008 Male 255 lb 3/5/2009 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 5/27/2008 Female 116 lb 3/13/2009 Brazil
Primary
Concomitant
Nasal Cyst Other Serious 55 Male 3/18/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/8/2008 42 Female 3/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 2/10/2009 Male 255 lb 3/19/2009 Physician United States
Primary
Concomitant
Pregnancy Other Serious 38 Female 3/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Injection Site Reaction Other Serious 38 Female 3/26/2009 Physician Nigeria
Primary
Secondary
Pregnancy Other Serious 38 Female 3/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Injection Site Reaction Other Serious 38 Female 3/30/2009 Other Health Professional
Primary
Secondary
Lipodystrophy Acquired Other Serious 40 Male 4/15/2009 Other Health Professional United States
Primary
Secondary
Paranasal Cyst Other Serious 55 Male 5/26/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Paranasal Cyst Other Serious 55 Male 6/5/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/15/2008 52 Male 130 lb 6/10/2009 Physician United States
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 7/31/2009
Primary
Secondary
Rhabdomyolysis Other Serious 7/15/2008 52 130 lb 8/6/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/8/2008 42 Female 8/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperlipidaemia Hospitalization Male 8/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperlipidaemia Hospitalization Male 8/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/8/2008 42 Female 8/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 9/8/2009 Consumer United States
Primary
Secondary
Weight Decreased Other Serious 9/8/2008 42 Female 9/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 9/17/2009 Other Health Professional Canada
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 9/23/2009 Other Health Professional Canada
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 9/29/2009 Other Health Professional Canada
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 10/7/2009
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 10/19/2009 Other Health Professional Canada
Primary
Secondary
Weight Decreased Other Serious 9/8/2008 42 Female 10/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 10/22/2009 Physician United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 11/24/2009 Other Health Professional United States
Primary
Secondary
Portal Hypertension Other Serious 12/3/2009 Physician United Kingdom
Primary
Secondary
Portal Hypertension Other Serious Male 12/24/2009
Primary
Secondary
Portal Hypertension Other Serious Male 1/5/2010 United Kingdom
Primary
Secondary
Gastrointestinal Malformation Life Threatening 2/21/2009 1/16/2010 Other Health Professional
Primary
Secondary
Concomitant
Gastrointestinal Malformation Life Threatening 2/21/2009 1/22/2010 Other Health Professional
Primary
Secondary
Concomitant
Gastrointestinal Malformation Life Threatening 2/21/2009 1/29/2010 Other Health Professional
Primary
Secondary
Concomitant
Small For Dates Baby Congenital Anomaly 9/29/2009 Male 5 lb 2/1/2010 United States
Primary
Concomitant
Small For Dates Baby Other Serious 9/29/2009 Male 5 lb 2/2/2010 United States
Primary
Secondary
Premature Labour Other Serious 2/21/2009 Female 163 lb 2/12/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Premature Labour Other Serious 2/21/2009 Female 163 lb 2/16/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 3/3/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 3/4/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 3/4/2010 Other Health Professional United States
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 3/4/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 3/4/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 3/8/2010 Physician Canada
Primary
Secondary
Premature Labour Other Serious 2/21/2009 Female 163 lb 3/9/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Umbilical Cord Abnormality Life Threatening 2/21/2009 Female 4 lb 3/9/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 3/11/2010 Physician Canada
Primary
Secondary
Umbilical Cord Abnormality Life Threatening 2/21/2009 Female 4 lb 3/16/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Hypertrophy Death 6/10/2009 Female 7 lb 3/19/2010 United States
Primary
Secondary
Umbilical Cord Abnormality Life Threatening 2/21/2009 Female 4 lb 3/24/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/7/2008 44 Male 123 lb 3/29/2010 Physician Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/18/2008 55 Female 147 lb 3/29/2010 Physician Brazil
Primary
Secondary
Concomitant
Ventricular Hypertrophy Death 6/10/2009 Female 7 lb 3/30/2010 United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 4/1/2010 Physician Canada
Primary
Secondary
Sudden Infant Death Syndrome Death 6/10/2009 -1 Female 8 lb 4/12/2010 Physician United Kingdom
Primary
Secondary
Sepsis Hospitalization 4/7/2008 44 Male 123 lb 4/12/2010 Physician Brazil
Primary
Secondary
Concomitant
Sudden Infant Death Syndrome Death 6/10/2009 0 Female 8 lb 4/13/2010 Consumer United Kingdom
Primary
Secondary
Pre-eclampsia Other Serious 21 Female 4/15/2010 United States
Primary
Secondary
Premature Baby Other Serious 1/15/2010 Female 15 lb 4/15/2010 United States
Primary
Secondary
Sudden Infant Death Syndrome Other Serious 6/10/2009 Female 8 lb 4/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Hospitalization 1/1/2008 55 Female 147 lb 4/23/2010 Physician Brazil
Primary
Secondary
Concomitant
Premature Labour Hospitalization 42 Female 4/28/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Hypertrophy Death 6/10/2009 0 Female 7 lb 4/28/2010 Physician United Kingdom
Primary
Secondary
Umbilical Cord Abnormality Life Threatening 2/21/2009 Female 4 lb 4/28/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 4/28/2010 Physician Canada
Primary
Secondary
Ventricular Hypertrophy Other Serious 6/10/2009 0 Female 8 lb 4/26/2010 Physician United Kingdom
Primary
Secondary
Ventricular Hypertrophy Other Serious 6/10/2009 Female 8 lb 5/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 5/4/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/4/2010 Other Health Professional United States
Primary
Secondary
Ventricular Hypertrophy Death 6/10/2009 0 Female 8 lb 5/4/2010 Physician United Kingdom
Primary
Secondary
Ventricular Hypertrophy Death 6/10/2009 0 Female 8 lb 5/6/2010 Consumer United Kingdom
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/7/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 5/7/2010 Consumer United States
Primary
Secondary
Ventricular Hypertrophy Death 6/10/2009 -1 Female 8 lb 5/7/2010 Physician United Kingdom
Primary
Secondary
Ventricular Hypertrophy Death 6/10/2009 Female 7 lb 5/7/2010 United States
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 5/11/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/12/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/13/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/13/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/14/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/14/2010 Other Health Professional United States
Primary
Secondary
Rash Other Serious 5/1/2005 34 Female 5/17/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 5/17/2010 Physician Canada
Primary
Secondary
Ventricular Hypertrophy Other Serious 6/10/2009 0 Female 8 lb 5/13/2010 Physician
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/18/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/18/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/21/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/24/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/28/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/28/2010 Physician United States
Primary
Secondary
Ventricular Hypertrophy Death 6/10/2009 0 Female 7 lb 6/1/2010 Physician United Kingdom
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 6/3/2010 United States
Primary
Secondary
Drug Exposure During Pregnancy Other Serious Female 6/4/2010 Other Health Professional Austria
Primary
Secondary
Ventricular Hypertrophy Other Serious 0 Female 6/4/2010 Other Health Professional Austria
Primary
Secondary
Premature Labour Hospitalization 2/21/2009 42 Female 6/16/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Umbilical Cord Abnormality Life Threatening 2/21/2009 Female 4 lb 6/16/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/18/2008 55 Female 147 lb 6/18/2010 Physician Brazil
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 6/21/2010 Physician Canada
Primary
Secondary
Premature Baby Other Serious 1/15/2010 Female 15 lb 6/21/2010 Consumer United States
Primary
Secondary

Drug Data