Darunavir combined with Tenofovir

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Lactic Acidosis Hospitalization 7/25/2006 62 Male 8/31/2006 Physician Brazil
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/25/2006 62 Male 9/6/2006 Physician Brazil
Primary
Secondary
Concomitant
Osteomyelitis Bacterial Other Serious 11/23/2006 Male 1/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 2/5/2007 62 Male 2/12/2007 Physician United States
Primary
Secondary
Concomitant
Urine Output Decreased Life Threatening 2/12/2007 57 Male 181 lb 4/26/2007 Physician Canada
Primary
Secondary
Concomitant
Tachycardia Other Serious 10 Female 6/12/2007 Consumer Canada
Primary
Secondary
Concomitant
Inflammation Hospitalization 10/12/2007 45 Male 12/13/2007 Australia
Primary
Secondary
Concomitant
Vision Blurred Other Serious 12/1/2007 23 Female 2/1/2008 Netherlands
Primary
Secondary
Concomitant
Underdose Hospitalization 1/1/2007 45 Male 2/15/2008 Physician Australia
Primary
Secondary
Concomitant
Portal Hypertension Hospitalization 2/20/2008 58 Male 3/24/2008 Australia
Primary
Secondary
Concomitant
Portal Hypertension Hospitalization 2/20/2008 58 Male 3/27/2008 Australia
Primary
Secondary
Concomitant
Hepatic Cirrhosis Hospitalization 2/20/2008 58 Male 4/1/2008 Australia
Primary
Secondary
Concomitant
Abortion Induced Other Serious 3/17/2008 38 Female 4/30/2008 United States
Primary
Secondary
Pyrexia Hospitalization 4/7/2008 Male 123 lb 5/5/2008 Brazil
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/7/2008 Male 123 lb 5/12/2008 Brazil
Primary
Secondary
Concomitant
Disease Progression Death Female 87 lb 5/23/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 4/18/2008 Female 147 lb 5/30/2008 Brazil
Primary
Secondary
Concomitant
Lipodystrophy Acquired Other Serious 10/1/2007 21 Female 141 lb 7/3/2008 Other Health Professional United States
Primary
Secondary
Drug Toxicity Hospitalization 12/1/2007 Female 181 lb 7/11/2008 Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/18/2008 Female 147 lb 7/11/2008 Brazil
Primary
Secondary
Concomitant
Death Death 1/1/2008 46 Male 137 lb 7/14/2008 Pharmacist Canada
Primary
Concomitant
Hepatitis B Death 1/1/2008 46 Male 137 lb 7/17/2008 Pharmacist Canada
Primary
Concomitant
Meningitis Cryptococcal Hospitalization 7/19/2005 Male 8/4/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/6/2007 43 Male 8/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myalgia Hospitalization 9/7/2001 Male 8/28/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 22 Male 9/12/2008 Physician United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 22 Male 9/17/2008 United States
Primary
Secondary
Concomitant
Meningitis Cryptococcal Hospitalization 7/19/2005 Male 9/23/2008 Physician Japan
Primary
Secondary
Concomitant
Myalgia Hospitalization 9/7/2001 Male 10/2/2008 Japan
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 8/12/2008 Female 141 lb 10/8/2008 Brazil
Primary
Concomitant
Prostate Cancer Recurrent Other Serious 12/22/2003 Male 176 lb 11/5/2008
Primary
Secondary
Concomitant
Meningitis Cryptococcal Hospitalization 7/19/2005 Male 11/7/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/31/2008 Male 12/1/2008 France
Primary
Concomitant
Wegener's Granulomatosis Hospitalization Male 12/16/2008 Physician Germany
Primary
Concomitant
Wegener's Granulomatosis Hospitalization 1/1/2008 45 Male 1/6/2009 Physician Germany
Primary
Concomitant
Renal Failure Hospitalization 2/10/2009 Male 255 lb 3/4/2009 Physician United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 12/26/2008 Male 255 lb 3/5/2009 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 2/10/2009 Male 255 lb 3/19/2009 Physician United States
Primary
Concomitant
Pregnancy Other Serious 38 Female 3/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Pneumococcal Bacteraemia Hospitalization 3/2/2009 3/24/2009 Physician Brazil
Primary
Concomitant
Injection Site Reaction Other Serious 38 Female 3/26/2009 Physician Nigeria
Primary
Secondary
Pregnancy Other Serious 38 Female 3/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Injection Site Reaction Other Serious 38 Female 3/30/2009 Other Health Professional
Primary
Secondary
Platelet Count Decreased Other Serious 3/20/2009 Male 190 lb 4/10/2009 Physician Australia
Primary
Secondary
Concomitant
Lipodystrophy Acquired Other Serious 40 Male 4/15/2009 Other Health Professional United States
Primary
Secondary
Thrombocytopenia Other Serious 4/2/2009 4/29/2009 Physician Brazil
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 1/30/2009 4/29/2009 Physician
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 2/8/2009 49 Female 5/28/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Other Serious 1/1/2009 44 Male 6/5/2009 Pharmacist Ireland
Primary
Concomitant
Visual Impairment Life Threatening 2/1/2009 Female 247 lb 6/12/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Disability 1/1/2009 Male 159 lb 6/18/2009 Physician Brazil
Primary
Secondary
Concomitant
Death Death Male 178 lb 6/22/2009 Physician United States
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious Male 6/25/2009 Physician Australia
Primary
Secondary
Concomitant
Visual Impairment Other Serious 2/1/2009 Female 247 lb 6/26/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/31/2008 Male 7/3/2009 Physician France
Primary
Concomitant
Abdominal Mass Hospitalization 2/1/2009 4/3/2009 Physician Brazil
Primary
Concomitant
Pseudomyxoma Peritonei Other Serious 2/11/2009 Male 173 lb 7/14/2009 Brazil
Primary
Concomitant
Platelet Count Decreased Other Serious 3/20/2009 Male 190 lb 7/15/2009 Physician Australia
Primary
Secondary
Concomitant
Pain In Extremity Death Male 178 lb 7/16/2009 Physician United States
Primary
Secondary
Concomitant
Paraesthesia Disability 12/10/2008 Male 7/20/2009 Pharmacist Ireland
Primary
Secondary
Concomitant
Death Death Male 178 lb 7/24/2009 Physician United States
Primary
Secondary
Concomitant
Rash Morbilliform Other Serious 49 Female 7/27/2009 Physician United States
Primary
Secondary
Concomitant
Death Death Male 178 lb 7/29/2009 Physician United States
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 7/31/2009
Primary
Secondary
Toxic Epidermal Necrolysis Life Threatening 2/8/2009 49 Female 8/13/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/20/2009 Male 190 lb 8/13/2009 Physician Australia
Primary
Secondary
Concomitant
Transplant Failure Other Serious 41 Male 8/14/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Interacting
Toxic Epidermal Necrolysis Life Threatening 2/8/2009 49 Female 8/19/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Cushing's Syndrome Other Serious 9/27/2006 Male 151 lb 8/20/2009 Ireland
Primary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 9/8/2009 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 9/17/2009 Other Health Professional Canada
Primary
Secondary
Upper Limb Fracture Death 5/25/2009 Male 178 lb 9/18/2009 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 50 Male 9/18/2009 Other Health Professional France
Primary
Secondary
Myalgia Hospitalization 9/7/2001 Male 9/18/2009 Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/20/2009 Male 190 lb 10/1/2009 Physician Australia
Primary
Secondary
Concomitant
Paraesthesia Disability 12/10/2008 Male 10/2/2009 Pharmacist Ireland
Primary
Secondary
Concomitant
Pseudomyxoma Peritonei Other Serious 2/11/2009 50 10/9/2009 Brazil
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 1/1/2009 40 Female 10/13/2009 Consumer Brazil
Primary
Secondary
Concomitant
Ophthalmoplegia Other Serious 52 Male 10/7/2009
Primary
Secondary
Stevens-johnson Syndrome Other Serious 1/1/2009 40 Female 10/14/2009 Consumer United States
Primary
Secondary
Drug Toxicity Hospitalization 12/1/2007 23 10/16/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 10/19/2009 Other Health Professional Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 10/22/2009 Physician United States
Primary
Secondary
Sepsis Other Serious 2/11/2009 Male 164 lb 10/26/2009 Other Health Professional Brazil
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 51 Male 10/29/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Portal Hypertension Other Serious 12/3/2009 Physician United Kingdom
Primary
Secondary
Portal Hypertension Other Serious 12/3/2009 Physician United Kingdom
Primary
Secondary
Portal Hypertension Other Serious Male 12/24/2009
Primary
Secondary
Portal Hypertension Other Serious Male 1/5/2010 United Kingdom
Primary
Secondary
Myocardial Ischaemia Life Threatening 10/3/2008 52 Male 161 lb 1/6/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Chronic Life Threatening 10/3/2008 52 Male 12/30/2009 Spain
Primary
Secondary
Concomitant
Angina Unstable Life Threatening 10/3/2008 Male 162 lb 1/8/2010 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/20/2009 Male 190 lb 1/27/2010 Physician Australia
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 1/1/2009 40 Female 1/28/2010 Consumer Brazil
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 3/3/2010 Physician Canada
Primary
Secondary
Nausea Life Threatening 9/21/2009 42 Female 2/11/2010 Physician United States
Primary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 3/4/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 3/4/2010 Other Health Professional United States
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 3/4/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 3/4/2010 Consumer United States
Primary
Secondary
Sepsis Other Serious 2/11/2009 Male 164 lb 3/8/2010 Brazil
Primary
Concomitant
Muscle Rupture Hospitalization 11/28/2009 Male 213 lb 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/7/2008 44 Male 123 lb 3/29/2010 Physician Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/18/2008 55 Female 147 lb 3/29/2010 Physician Brazil
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/5/2010 44 Female 132 lb 4/2/2010 Physician United Kingdom
Primary
Secondary
Sepsis Hospitalization 4/7/2008 44 Male 123 lb 4/12/2010 Physician Brazil
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/5/2010 44 Female 132 lb 4/13/2010 Consumer United Kingdom
Primary
Secondary
Type 2 Diabetes Mellitus Other Serious 1/5/2010 49 Female 132 lb 4/15/2010 Physician United Kingdom
Primary
Secondary
Toxic Epidermal Necrolysis Life Threatening 2/8/2009 49 Female 4/20/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Odynophagia Required Intervention 63 Male 4/8/2010 France
Primary
Secondary
Concomitant
Sepsis Other Serious 2/11/2009 50 Male 164 lb 4/22/2010 Other Health Professional Brazil
Primary
Concomitant
Vomiting Hospitalization 1/1/2008 55 Female 147 lb 4/23/2010 Physician Brazil
Primary
Secondary
Concomitant
Visual Impairment Other Serious 2/3/2009 49 Female 247 lb 4/29/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious Male 5/3/2010 Pharmacist United States
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 5/14/2010 Other Health Professional United States
Primary
Secondary
Rash Other Serious 5/1/2005 34 Female 5/17/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 5/18/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/28/2010 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 4/18/2008 55 Female 147 lb 6/18/2010 Physician Brazil
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 6/25/2010 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 4/18/2008 55 Female 147 lb 6/25/2010 Physician Brazil
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Required Intervention 52 Male 6/14/2010 Other Health Professional United States
Primary
Secondary
Skin Lesion Hospitalization 50 Male 7/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 7/22/2010 Other Health Professional United States
Primary
Secondary
Radiculopathy Hospitalization 50 Male 7/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 8/16/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 8/16/2010 Other Health Professional United States
Primary
Secondary
Skin Lesion Hospitalization 50 Male 8/17/2010 Physician United Kingdom
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 10/6/2010 Other Health Professional United States
Primary
Secondary
Virologic Failure Other Serious 62 Male 10/14/2010 Consumer Germany
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 10/18/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 10/18/2010 Other Health Professional United States
Primary
Secondary
Sepsis Hospitalization 4/7/2008 44 Male 123 lb 10/22/2010 Physician Brazil
Primary
Secondary
Concomitant
Renal Failure Other Serious 42 Male 10/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 11/1/2010 Consumer United States
Primary
Secondary
Headache Hospitalization 43 Male 1/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Weight Increased Other Serious 1/1/2010 47 Female 2/16/2011 Physician United Kingdom
Primary
Concomitant
Sepsis Hospitalization 1/1/2010 51 Male 4/8/2011 Physician Italy
Primary
Secondary
Concomitant
Anaemia Hospitalization 2/8/2009 49 Female 247 lb 8/3/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Dermatitis Allergic Hospitalization 22 Female 9/2/2011 Physician Romania
Primary
Secondary
Concomitant
Rash Erythematous Hospitalization 22 Female 9/19/2011 Physician Romania
Primary
Secondary
Concomitant
Hypoaesthesia Hospitalization 10/28/2009 35 Male 1/3/2012 Physician Japan
Primary
Secondary
Concomitant
Plasmablastic Lymphoma Other Serious 1/1/2011 40 Female 160 lb 2/10/2012 Physician Brazil
Primary
Concomitant
Arrhythmia Hospitalization Male 132 lb 8/30/2012 Physician Pl
Primary
Secondary
Respiratory Failure Other Serious 62 Male 9/18/2012 Consumer Country Not Specified
Primary
Concomitant
Nephrolithiasis Other Serious 9/11/2012 Physician Us
Primary
Secondary
Off Label Use Other Serious 41 Male 11/2/2012 Physician Ch
Primary
Secondary
Concomitant
Interacting
Nephrolithiasis Hospitalization 11/22/2012 42 Male 12/7/2012 Physician De
Primary
Secondary
Concomitant
Urinary Tract Obstruction Hospitalization 11/20/2012 43 Male 12/13/2012 Physician Country Not Specified
Primary
Concomitant
Secondary Hypertension Other Serious 2008 43 Male 12/18/2012 Other Health Professional Gb
Primary
Secondary
Interacting

Drug Data