Darunavir combined with Ritonavir

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Lactic Acidosis Hospitalization 7/25/2006 62 Male 8/31/2006 Physician Brazil
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/25/2006 62 Male 9/6/2006 Physician Brazil
Primary
Secondary
Concomitant
Gynaecomastia Hospitalization 8/22/2006 Male 10/3/2006 United Kingdom
Primary
Secondary
Concomitant
Vertigo Disability 9/15/2006 Male 1/3/2007 France
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 3/1/2005 39 Male 150 lb 1/29/2007 Consumer France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/23/2006 Female 2/1/2007 United States
Primary
Secondary
Concomitant
Death Death 2/5/2007 62 Male 2/12/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/23/2006 10 Female 46 lb 2/14/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Haemorrhage Intracranial Hospitalization 1/1/2007 50 Male 4/16/2007 Physician United States
Primary
Concomitant
Urine Output Decreased Life Threatening 2/12/2007 57 Male 181 lb 4/26/2007 Physician Canada
Primary
Secondary
Concomitant
Rectal Haemorrhage Life Threatening 4/20/2007 54 Male 6/1/2007 Physician United Kingdom
Primary
Secondary
Tachycardia Other Serious 10 Female 6/12/2007 Consumer Canada
Primary
Secondary
Concomitant
Septic Shock Hospitalization 8/19/2007 45 Male 9/4/2007 Physician Malaysia
Primary
Secondary
Concomitant
Renal Tubular Disorder Disability 12/1/2006 Male 161 lb 9/20/2007 Physician France
Primary
Secondary
Concomitant
Weight Decreased 12/12/2006 57 Male 2/22/2007 Physician United States
Primary
Secondary
Concomitant
Abortion Spontaneous Other Serious 5/30/2007 25 Female 10/17/2007 United States
Primary
Secondary
Abortion Spontaneous Other Serious 5/30/2007 25 Female 10/30/2007 United States
Primary
Secondary
Ultrasound Antenatal Screen Abnormal Other Serious 5/3/2007 36 Female 10/30/2007 United States
Primary
Secondary
Medication Error Hospitalization 10/12/2007 45 Male 10/30/2007 Australia
Primary
Secondary
Concomitant
Incorrect Dose Administered Hospitalization 10/12/2007 45 Male 11/2/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Haemorrhage Intracranial Hospitalization 1/1/2007 50 Male 11/20/2007 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 10/25/2007 49 Unknown 11/27/2007 Netherlands
Primary
Concomitant
Inflammation Hospitalization 10/12/2007 45 Male 12/13/2007 Australia
Primary
Secondary
Concomitant
Placenta Praevia 9/27/2007 36 Female 12/20/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 10/30/2007 36 Male 1/8/2008 Physician France
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 12/10/2006 Male 218 lb 1/14/2008 United States
Primary
Secondary
Concomitant
Abdominal Pain Required Intervention 12/3/2007 42 Male 12/11/2007 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Other Serious 1/2/2008 52 Male 1/23/2008 France
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 10/30/2007 36 Male 2/7/2008 Physician France
Primary
Concomitant
Micrognathia Congenital Anomaly 10/14/2005 Male 7 lb 2/8/2008 United States
Primary
Secondary
Staphylococcal Skin Infection Hospitalization 1/1/2007 45 Male 1/24/2008 Australia
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 10/30/2007 36 Male 99 lb 2/18/2008 Physician France
Primary
Concomitant
Micrognathia Congenital Anomaly Male 7 lb 2/6/2008 Other Health Professional United States
Primary
Secondary
Renal Tubular Necrosis Hospitalization 10/30/2007 36 Male 99 lb 2/21/2008 Physician France
Primary
Concomitant
Underdose Hospitalization 1/1/2007 45 Male 2/15/2008 Physician Australia
Primary
Secondary
Concomitant
Micrognathia Congenital Anomaly 10/14/2005 Male 2/27/2008 Physician United Kingdom
Primary
Secondary
Liver Function Test Abnormal Other Serious 6/27/2007 44 Male 3/3/2008 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 10/30/2007 36 Male 99 lb 3/6/2008 Physician France
Primary
Concomitant
Rash Generalised 11/13/2007 46 Female 2/8/2008 Physician United States
Primary
Concomitant
Low Density Lipoprotein Increased 2/27/2007 54 Female 2/8/2008 United States
Primary
Concomitant
Rash Hospitalization 12/25/2007 64 Male 3/11/2008 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 1/2/2008 52 Male 3/3/2008 France
Primary
Concomitant
Liver Function Test Abnormal Other Serious 6/27/2007 44 Male 3/19/2008 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 10/30/2007 36 Male 99 lb 3/26/2008 Physician France
Primary
Concomitant
Portal Hypertension Hospitalization 2/20/2008 58 Male 3/24/2008 Australia
Primary
Secondary
Concomitant
Jaundice Life Threatening 12/1/2007 48 Male 3/27/2008 Other Health Professional France
Primary
Secondary
Concomitant
Portal Hypertension Hospitalization 2/20/2008 58 Male 3/27/2008 Australia
Primary
Secondary
Concomitant
Jaundice Life Threatening 12/1/2007 48 Male 4/1/2008 Other Health Professional France
Primary
Secondary
Concomitant
Hepatic Cirrhosis Hospitalization 2/20/2008 58 Male 4/1/2008 Australia
Primary
Secondary
Concomitant
Haematoma Hospitalization 2/3/2008 32 Male 4/10/2008 Other Health Professional France
Primary
Secondary
Rotator Cuff Syndrome Death 1/22/2008 Male 4/11/2008 Other Health Professional Canada
Primary
Concomitant
Weight Decreased Hospitalization 1/2/2008 41 Male 4/7/2008 United Kingdom
Primary
Secondary
Concomitant
Drug Eruption Hospitalization 3/17/2008 43 Male 4/11/2008 France
Primary
Concomitant
Ultrasound Antenatal Screen Abnormal Other Serious 5/3/2007 36 Female 4/15/2008 United States
Primary
Secondary
Rhabdomyolysis Hospitalization 4/1/2008 44 Female 4/21/2008 Physician France
Primary
Secondary
Rhabdomyolysis Hospitalization 4/1/2008 44 Female 4/22/2008 Physician France
Primary
Secondary
Blood Creatine Phosphokinase Increased Other Serious 10/9/2007 39 Male 4/17/2008 Physician France
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 2/25/2008 43 Male 4/18/2008 Spain
Primary
Secondary
Concomitant
Chest Pain Hospitalization 4/7/2008 Male 4/28/2008 Australia
Primary
Concomitant
Hypokalaemia Hospitalization 4/9/2008 Male 168 lb 4/28/2008 France
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/2/2008 52 Male 4/24/2008 Physician France
Primary
Concomitant
Abnormal Behaviour Hospitalization Female 219 lb 4/30/2008 United States
Primary
Concomitant
Haematoma Hospitalization 2/3/2008 32 Male 5/1/2008 Other Health Professional France
Primary
Secondary
Folliculitis Hospitalization 3/17/2008 43 Male 5/1/2008 France
Primary
Concomitant
Pyrexia Hospitalization 4/7/2008 Male 123 lb 5/5/2008 Brazil
Primary
Secondary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 7/1/2007 57 Male 185 lb 5/6/2008 Physician France
Primary
Concomitant
Myalgia Disability 8/31/2007 47 Male 5/7/2008 Other Health Professional France
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 4/9/2008 48 Male 5/8/2008 France
Primary
Secondary
Concomitant
Coronary Artery Disease Other Serious 2/13/2008 Male 213 lb 5/9/2008 Canada
Primary
Concomitant
Chest Pain Hospitalization 4/7/2008 Male 5/9/2008 Australia
Primary
Concomitant
Pyrexia Hospitalization 4/7/2008 Male 123 lb 5/12/2008 Brazil
Primary
Secondary
Concomitant
Rash Generalised 11/13/2007 46 Female 5/9/2008 Physician United States
Primary
Concomitant
Viral Load Increased 1/7/2008 47 Male 5/9/2008 Other Health Professional United States
Primary
Concomitant
Blood Triglycerides Increased Male 5/9/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/2/2008 41 Male 5/13/2008 United Kingdom
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 10/10/2007 56 Male 174 lb 5/19/2008 Physician Canada
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 5/28/2007 57 Male 185 lb 5/22/2008 Physician France
Primary
Concomitant
Disease Progression Death Female 87 lb 5/23/2008 Other Health Professional United States
Primary
Concomitant
Abnormal Behaviour Hospitalization Female 219 lb 5/23/2008 United States
Primary
Concomitant
Pregnancy Other Serious 5/3/2007 36 Female 5/23/2008 United States
Primary
Secondary
Hepatic Failure Other Serious 4/1/2008 Male 137 lb 5/23/2008 Spain
Primary
Secondary
Concomitant
Post Procedural Complication Other Serious 10/9/2007 39 Male 5/16/2008 Physician France
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 11/1/2007 65 Male 5/22/2008 Physician Australia
Primary
Secondary
Hypokalaemia Hospitalization 4/9/2008 Male 168 lb 5/30/2008 France
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/18/2008 Female 147 lb 5/30/2008 Brazil
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 9/25/2007 56 Male 174 lb 6/3/2008 Physician Canada
Primary
Concomitant
Haematoma Hospitalization 2/3/2008 32 Male 6/4/2008 Other Health Professional France
Primary
Secondary
Hypokalaemia Hospitalization 4/9/2008 48 Male 6/5/2008 France
Primary
Secondary
Concomitant
Scapula Fracture Hospitalization 5/30/2008 Male 166 lb 6/10/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/18/2008 Female 147 lb 6/11/2008 Brazil
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 4/1/2008 Male 137 lb 6/12/2008 Spain
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/1/2007 45 Male 6/13/2008 Other Health Professional France
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 2/25/2008 43 Male 6/13/2008 Spain
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/1/2007 45 Male 6/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Convulsion Hospitalization 5/29/2008 Male 166 lb 6/20/2008 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/7/2008 Male 123 lb 6/23/2008 Brazil
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/1/2007 45 Male 6/25/2008 Other Health Professional France
Primary
Secondary
Concomitant
Acute Coronary Syndrome Hospitalization 4/22/2008 Male 6/27/2008 Netherlands
Primary
Concomitant
Vomiting Hospitalization 4/18/2008 Female 147 lb 6/27/2008 Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/19/2008 59 Male 6/25/2008 Physician France
Primary
Secondary
Concomitant
Viral Load Increased Other Serious 24 Female 7/9/2008 United States
Primary
Concomitant
Burkitt's Lymphoma Other Serious 12/28/2007 58 Male 7/10/2008 Physician United States
Primary
Concomitant
Burkitt's Lymphoma Other Serious 12/28/2007 58 Male 7/11/2008 Physician United States
Primary
Concomitant
Drug Toxicity Hospitalization 12/1/2007 Female 181 lb 7/11/2008 Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/18/2008 Female 147 lb 7/11/2008 Brazil
Primary
Secondary
Concomitant
Death Death 1/1/2008 46 Male 137 lb 7/14/2008 Pharmacist Canada
Primary
Concomitant
Myositis Other Serious 11/28/2007 52 Male 7/16/2008 Physician France
Primary
Secondary
Concomitant
Hepatitis B Death 1/1/2008 46 Male 137 lb 7/17/2008 Pharmacist Canada
Primary
Concomitant
Myositis Other Serious 11/28/2007 52 Male 7/18/2008 Physician France
Primary
Secondary
Concomitant
Pancreatitis Other Serious 7/1/2008 51 Female 112 lb 7/24/2008 Physician Switzerland
Primary
Secondary
Concomitant
Nausea 7/25/2008 United States
Primary
Secondary
Diarrhoea 7/25/2008 United States
Primary
Secondary
Rash Maculo-papular 7/25/2008 United States
Primary
Secondary
Hepatitis C Hospitalization 6/9/2008 54 Male 281 lb 7/28/2008 Pharmacist United States
Primary
Secondary
Hypokalaemia Hospitalization 4/9/2008 Male 168 lb 8/1/2008 France
Primary
Secondary
Concomitant
Procedural Pain Other Serious 2/13/2008 Male 213 lb 8/5/2008 Canada
Primary
Concomitant
Hypokalaemia Hospitalization 4/9/2008 48 Male 8/6/2008 France
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/15/2008 52 Male 130 lb 7/31/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/15/2008 52 Male 130 lb 7/31/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/11/2007 45 Male 8/11/2008 Physician United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 4/7/2008 Male 8/11/2008 Australia
Primary
Concomitant
Vomiting Hospitalization 6/11/2007 45 Male 8/13/2008 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/27/2007 44 Male 8/15/2008 United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 11/1/2007 65 Male 8/15/2008 Australia
Primary
Secondary
Rhabdomyolysis Hospitalization 3/31/2008 44 Female 8/22/2008 Other Health Professional France
Primary
Secondary
Concomitant
Coronary Artery Disease Other Serious 2/13/2008 Male 213 lb 8/25/2008 Canada
Primary
Concomitant
Rash Maculo-papular Other Serious 12/17/2007 Male 8/26/2008 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 3/31/2008 44 Female 8/27/2008 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 8/2/2008 48 Male 8/28/2008 Other Health Professional France
Primary
Secondary
Liver Function Test Abnormal Other Serious 6/27/2007 44 Male 9/5/2008 United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/1/2007 45 Male 9/9/2008 Other Health Professional France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/9/2008 43 Male 165 lb 9/10/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 22 Male 9/12/2008 Physician United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 22 Male 9/17/2008 United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 9/16/2008 42 Female 10/2/2008 France
Primary
Secondary
Concomitant
Pericarditis Hospitalization 9/19/2008 20 Male 10/2/2008 Pharmacist Ireland
Primary
Concomitant
Rhabdomyolysis Hospitalization 7/15/2008 52 Male 130 lb 10/1/2008 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 9/16/2008 42 Female 10/7/2008 Other Health Professional France
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 8/12/2008 Female 141 lb 10/8/2008 Brazil
Primary
Concomitant
Rhabdomyolysis Hospitalization 7/15/2008 52 Male 130 lb 10/6/2008 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 9/16/2008 42 Female 10/10/2008 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 45 Male 10/20/2008 Pharmacist United Kingdom
Primary
Secondary
Neutropenia Hospitalization 9/16/2008 42 Female 10/21/2008 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Failure Death Male 10/22/2008 Consumer United States
Primary
Secondary
Myocardial Infarction Hospitalization 10/1/2008 Male 192 lb 10/22/2008 Canada
Primary
Secondary
Concomitant
Myalgia Disability 8/31/2007 47 Male 10/22/2008 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 45 Male 10/30/2008 Pharmacist United Kingdom
Primary
Secondary
Intra-uterine Death Death 10/25/2008 Male 10/30/2008 Physician France
Primary
Concomitant
Epistaxis Hospitalization 10/7/2008 55 Male 11/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Anal Cancer Recurrent Hospitalization 5/6/2008 Male 11/4/2008 France
Primary
Concomitant

Drug Data