Darunavir combined with Raltegravir

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Incorrect Dose Administered Hospitalization 10/12/2007 45 Male 11/2/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/1/2006 Male 174 lb 1/24/2008 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/1/2007 Male 1/24/2008 Other Health Professional France
Primary
Secondary
Concomitant
Paraesthesia Other Serious 52 Male 150 lb 1/29/2008 Other Health Professional United States
Primary
Concomitant
Cardiac Disorder Hospitalization 5/26/2007 Male 212 lb 2/1/2008 Consumer United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/4/2008 Male 2/15/2008 Consumer United Kingdom
Primary
Secondary
Underdose Hospitalization 1/1/2007 45 Male 2/15/2008 Physician Australia
Primary
Secondary
Concomitant
Viral Load Increased Other Serious Male 2/29/2008 Consumer United Kingdom
Primary
Secondary
Liver Function Test Abnormal Other Serious 6/27/2007 44 Male 3/3/2008 Physician United States
Primary
Secondary
Concomitant
Rash Hospitalization 12/25/2007 64 Male 3/11/2008 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 6/27/2007 44 Male 3/19/2008 Physician United States
Primary
Secondary
Concomitant
Rectal Cancer Other Serious 9/20/2007 Male 171 lb 3/28/2008 United States
Primary
Concomitant
Haematoma Hospitalization 2/3/2008 Male 4/10/2008 Other Health Professional France
Primary
Secondary
Rotator Cuff Syndrome Death 1/22/2008 Male 4/11/2008 Other Health Professional Canada
Primary
Concomitant
Hypokalaemia Hospitalization 4/9/2008 Male 168 lb 4/28/2008 France
Primary
Secondary
Concomitant
Abortion Induced Other Serious 9/25/2007 31 Female 4/30/2008 United States
Primary
Secondary
Abortion Induced Other Serious 3/17/2008 38 Female 4/30/2008 United States
Primary
Secondary
Coronary Artery Disease Other Serious 2/13/2008 Male 213 lb 5/9/2008 Canada
Primary
Concomitant
Hepatic Failure Other Serious 4/1/2008 Male 137 lb 5/23/2008 Spain
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 4/9/2008 Male 168 lb 5/30/2008 France
Primary
Secondary
Concomitant
Paraesthesia Other Serious 7/1/2006 Male 150 lb 6/3/2008 Other Health Professional United States
Primary
Concomitant
Hepatic Failure Other Serious 4/1/2008 Male 137 lb 6/12/2008 Spain
Primary
Secondary
Concomitant
Rash Other Serious 3/30/2008 Female 6/27/2008 Physician Spain
Primary
Concomitant
Hepatic Failure Other Serious 4/1/2008 Male 137 lb 7/3/2008 Physician United States
Primary
Secondary
Concomitant
Interacting
Lipodystrophy Acquired Other Serious 10/1/2007 21 Female 141 lb 7/3/2008 Other Health Professional United States
Primary
Secondary
Viral Load Increased Other Serious 24 Female 7/9/2008 United States
Primary
Concomitant
Viral Load Increased Other Serious 24 Female 7/11/2008 United States
Primary
Secondary
Drug Toxicity Hospitalization 12/1/2007 Female 181 lb 7/11/2008 Netherlands
Primary
Secondary
Concomitant
Respiratory Failure Death 7/14/2008 Male 7/30/2008 Physician Japan
Primary
Secondary
Hypokalaemia Hospitalization 4/9/2008 Male 168 lb 8/1/2008 France
Primary
Secondary
Concomitant
Meningitis Cryptococcal Hospitalization 7/19/2005 Male 8/4/2008 Physician Japan
Primary
Secondary
Concomitant
Procedural Pain Other Serious 2/13/2008 Male 213 lb 8/5/2008 Canada
Primary
Concomitant
Liver Function Test Abnormal Other Serious 6/27/2007 44 Male 8/15/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/30/2008 Female 8/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Coronary Artery Disease Other Serious 2/13/2008 Male 213 lb 8/25/2008 Canada
Primary
Concomitant
Myalgia Hospitalization 9/7/2001 Male 8/28/2008 Physician Japan
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 6/27/2007 44 Male 9/5/2008 United States
Primary
Secondary
Concomitant
Angina Unstable Hospitalization 9/3/2008 48 Male 157 lb 9/16/2008 United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/29/2006 Male 172 lb 9/18/2008 Ireland
Primary
Concomitant
Meningitis Cryptococcal Hospitalization 7/19/2005 Male 9/23/2008 Physician Japan
Primary
Secondary
Concomitant
Angina Unstable Hospitalization 9/3/2008 48 Male 157 lb 9/26/2008 United States
Primary
Secondary
Concomitant
Myalgia Hospitalization 9/7/2001 Male 10/2/2008 Japan
Primary
Secondary
Concomitant
Epistaxis Other Serious 10/7/2008 55 Male 161 lb 10/16/2008 United States
Primary
Secondary
Respiratory Failure Death Male 10/22/2008 Consumer United States
Primary
Secondary
Myocardial Infarction Hospitalization 10/1/2008 Male 192 lb 10/22/2008 Canada
Primary
Secondary
Concomitant
Respiratory Failure Death Male 10/28/2008 Consumer United States
Primary
Secondary
Glomerular Filtration Rate Decreased Other Serious 10/7/2008 55 Male 161 lb 10/28/2008 United States
Primary
Secondary
Concomitant
Epistaxis Hospitalization 10/7/2008 55 Male 11/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Anal Cancer Recurrent Hospitalization 5/6/2008 Male 11/4/2008 France
Primary
Concomitant
B-cell Lymphoma Hospitalization 4/9/2008 69 Male 163 lb 11/6/2008 United States
Primary
Secondary
Concomitant
Meningitis Cryptococcal Hospitalization 7/19/2005 Male 11/7/2008 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Death Male 11/12/2008 Consumer United States
Primary
Secondary
Respiratory Failure Death Male 11/13/2008 Consumer United States
Primary
Secondary
Bladder Neoplasm Other Serious 9/8/2008 Female 95 lb 11/18/2008 United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 45 Male 11/19/2008 Other Health Professional United States
Primary
Secondary
Interacting
Stillbirth Other Serious 10/25/2008 40 Female 11/24/2008 United States
Primary
Secondary
Drug Interaction Other Serious 45 Male 11/26/2008 Other Health Professional United States
Primary
Secondary
Interacting
Immune Reconstitution Syndrome Other Serious 10/12/2008 Male 158 lb 11/28/2008 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/12/2008 19 Female 116 lb 11/28/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/31/2008 Male 12/1/2008 France
Primary
Concomitant
Haematoma Hospitalization 2/3/2008 Male 12/11/2008 Other Health Professional France
Primary
Secondary
Rash Maculo-papular Other Serious 11/1/2008 12/16/2008 Pharmacist France
Primary
Concomitant
Interacting
Colon Cancer Other Serious 9/8/2008 Female 95 lb 12/19/2008 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 10/4/2008 Male 191 lb 1/16/2009 Other Health Professional Canada
Primary
Concomitant
Interacting
Weight Decreased Hospitalization 9/22/2008 42 Female 1/29/2009 United States
Primary
Secondary
Concomitant
Stress Hospitalization 41 Male 2/4/2009 Consumer United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 11/12/2008 Female 116 lb 2/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Death Male 2/23/2009 Consumer United States
Primary
Secondary
Respiratory Failure Death Male 2/23/2009 Consumer United States
Primary
Secondary
Respiratory Failure Death Male 2/26/2009 Consumer United States
Primary
Secondary
Respiratory Failure Death Male 2/27/2009 Consumer United States
Primary
Secondary
Thrombocytopenia Hospitalization 11/12/2008 Female 116 lb 3/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Death Male 3/5/2009 Consumer United States
Primary
Secondary
Respiratory Failure Death Male 3/5/2009 Consumer United States
Primary
Secondary
Thrombocytopenia Hospitalization 11/12/2008 Female 116 lb 3/5/2009 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/12/2008 Female 116 lb 3/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/12/2008 Female 116 lb 3/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/2/2009 3/11/2009 Physician France
Primary
Secondary
Concomitant
Neurological Symptom Hospitalization 2/15/2009 44 Male 3/12/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Death Male 3/12/2009 Consumer United States
Primary
Secondary
Respiratory Failure Death Male 3/12/2009 Consumer United States
Primary
Secondary
Disturbance In Attention Hospitalization 12/1/2008 3/13/2009 Physician France
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 45 Female 3/17/2009 Physician Brazil
Primary
Concomitant
Respiratory Failure Death Male 3/18/2009 Consumer United States
Primary
Secondary
Tearfulness Life Threatening 2/8/2009 49 Female 3/20/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/8/2008 42 Female 3/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neurological Symptom Hospitalization 2/15/2009 44 Male 3/20/2009 Physician United States
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 1/15/2009 38 Male 172 lb 3/19/2009 Physician United States
Primary
Secondary
Toxoplasmosis Hospitalization 33 3/23/2009 Physician Brazil
Primary
Concomitant
Epistaxis Hospitalization 10/7/2008 55 Male 3/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Epistaxis Hospitalization 10/7/2008 55 Male 3/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 45 Female 3/25/2009 Physician Brazil
Primary
Concomitant
Epistaxis Hospitalization 10/7/2008 55 Male 3/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/2/2009 3/23/2009 Physician France
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 1/10/2009 Male 159 lb 3/31/2009 Physician France
Primary
Concomitant
Pyelonephritis Hospitalization 1/15/2009 38 Male 172 lb 4/3/2009 Physician United States
Primary
Secondary
Disturbance In Attention Hospitalization 12/1/2008 4/6/2009 Physician France
Primary
Concomitant
Chest Pain Hospitalization 3/11/2009 49 Male 4/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/12/2008 Female 116 lb 4/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myositis Other Serious 1/1/2009 4/10/2009 Canada
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/20/2009 Male 190 lb 4/10/2009 Physician Australia
Primary
Secondary
Concomitant
Stress Hospitalization 41 Male 4/16/2009 Consumer United States
Primary
Secondary
Stress Hospitalization 41 Male 4/16/2009 Consumer United States
Primary
Secondary
Toxic Epidermal Necrolysis Life Threatening 2/8/2009 49 Female 4/20/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 2/8/2009 49 Female 4/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxoplasmosis Hospitalization 33 Male 4/28/2009 Physician Brazil
Primary
Concomitant
Dyspnoea Hospitalization 3/22/2009 Male 165 lb 4/30/2009 Other Health Professional United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 3/22/2009 Male 165 lb 5/13/2009 Other Health Professional United States
Primary
Concomitant
Chest Pain Hospitalization 4/21/2009 Female 196 lb 5/14/2009 Physician United States
Primary
Secondary
Concomitant
Rectal Polyp Hospitalization 7/28/2008 52 5/26/2009 Other Health Professional Australia
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 2/8/2009 49 Female 5/28/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 10/4/2008 57 5/28/2009 Other Health Professional Canada
Primary
Concomitant
Interacting
Visual Impairment Hospitalization 2/1/2009 Female 247 lb 5/29/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/7/2009 Male 119 lb 6/1/2009 Physician Australia
Primary
Concomitant
Renal Failure Acute Hospitalization 4/7/2009 Male 119 lb 6/2/2009 Physician Australia
Primary
Concomitant
Colon Cancer Disability 5/18/2009 Male 150 lb 6/3/2009 Other Health Professional United States
Primary
Concomitant
Visual Impairment Life Threatening 2/1/2009 Female 247 lb 6/12/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 2/1/2008 55 Male 6/19/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Interacting
Retinitis Other Serious 6/26/2008 Male 6/22/2009 Physician Brazil
Primary
Secondary
Concomitant
Death Death Male 178 lb 6/22/2009 Physician United States
Primary
Secondary
Concomitant
Retinal Detachment Other Serious 8/26/2008 59 Male 6/24/2009 Physician Brazil
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious Male 6/25/2009 Physician Australia
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 2/8/2009 49 Female 6/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Impairment Other Serious 2/1/2009 Female 247 lb 6/26/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/31/2008 Male 7/3/2009 Physician France
Primary
Concomitant
Toxoplasmosis Hospitalization 33 Male 7/13/2009 Physician Brazil
Primary
Concomitant
Abdominal Mass Hospitalization 2/1/2009 4/3/2009 Physician Brazil
Primary
Concomitant
Pseudomyxoma Peritonei Other Serious 2/11/2009 Male 173 lb 7/14/2009 Brazil
Primary
Concomitant
Platelet Count Decreased Other Serious 3/20/2009 Male 190 lb 7/15/2009 Physician Australia
Primary
Secondary
Concomitant
Pain In Extremity Death Male 178 lb 7/16/2009 Physician United States
Primary
Secondary
Concomitant
Paraesthesia Disability 12/10/2008 Male 7/20/2009 Pharmacist Ireland
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 7/22/2009 Other Health Professional Canada
Primary
Secondary
Hypotension Hospitalization 6/24/2009 Male 231 lb 7/22/2009 Physician Australia
Primary
Concomitant
Death Death Male 178 lb 7/24/2009 Physician United States
Primary
Secondary
Concomitant
Death Death Male 178 lb 7/29/2009 Physician United States
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 7/31/2009
Primary
Secondary
Chest Pain Hospitalization 3/11/2009 Male 173 lb 8/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Epistaxis Hospitalization 10/7/2008 55 Male 161 lb 8/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Mycobacterium Avium Complex Infection Hospitalization 7/24/2008 44 Male 188 lb 8/7/2009 Physician United States
Primary
Secondary
Concomitant
Hepatitis B Other Serious 11/3/2008 58 Male 230 lb 8/7/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/8/2008 42 Female 8/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperlipidaemia Hospitalization Male 8/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperlipidaemia Hospitalization Male 8/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 2/8/2009 49 Female 8/13/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 3/20/2009 Male 190 lb 8/13/2009 Physician Australia
Primary
Secondary
Concomitant
Stress Hospitalization 41 Male 8/13/2009 Consumer United States
Primary
Secondary
Thrombocytopenia Hospitalization 11/12/2008 Female 116 lb 8/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Failure Other Serious 41 Male 8/14/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Interacting
Toxoplasmosis Hospitalization 1/1/2009 33 Male 8/17/2009 Physician Brazil
Primary
Concomitant
Epistaxis Hospitalization 10/7/2008 55 Male 161 lb 8/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data