Darunavir combined with Norvir

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rhabdomyolysis Other Serious 3/1/2005 40 Male 150 lb 5/9/2006 Other Health Professional France
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Life Threatening 7/10/2006 Male 121 lb 11/1/2006 Physician
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/2/2006 56 Male 11/4/2006 Other Health Professional France
Primary
Secondary
Concomitant
Lactic Acidosis Death 10/5/2006 56 Male 11/6/2006 Consumer France
Primary
Secondary
Concomitant
Osteomyelitis Bacterial Other Serious 11/23/2006 Male 1/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 2/1/2007 30 Male 2/12/2007 Physician United States
Primary
Concomitant
Cardiac Disorder Hospitalization 1/1/2006 52 Male 2/20/2007 Consumer France
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 1/1/2006 42 Male 2/20/2007 Consumer France
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 12/18/2006 Male 2/22/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 5/17/2006 42 Male 2/26/2007 Other Health Professional France
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 51 Female 108 lb 3/7/2007 Consumer United States
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 10/9/2006 Male 192 lb 3/27/2007 Physician France
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 4/1/2007 32 Male 154 lb 6/18/2007 Consumer France
Primary
Secondary
Renal Colic Hospitalization 4/3/2007 32 Male 154 lb 6/20/2007 Physician France
Primary
Secondary
Weight Decreased Hospitalization 1/1/2007 52 Male 7/24/2007 Consumer France
Primary
Secondary
Concomitant
Anaemia Hospitalization 6/22/2007 Male 116 lb 7/26/2007 United States
Primary
Secondary
Concomitant
Local Swelling Other Serious 6/4/2007 40 Male 8/9/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Anaemia Hospitalization 6/22/2007 Male 115 lb 8/22/2007 United States
Primary
Secondary
Concomitant
Rash Generalised 4/13/2007 42 Female 130 lb 8/29/2007 Consumer United States
Primary
Concomitant
Renal Failure Chronic Other Serious 5/25/2004 Male 9/7/2007 Physician Japan
Primary
Secondary
Concomitant
Anaemia Hospitalization 6/22/2007 Male 115 lb 9/11/2007 United States
Primary
Secondary
Concomitant
Renal Failure Chronic Life Threatening 7/11/2006 36 Male 9/12/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/1/2004 Male 220 lb 9/14/2007 Physician France
Primary
Secondary
Concomitant
Renal Failure Chronic Life Threatening 7/11/2006 36 Male 9/19/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Chronic Life Threatening 7/11/2006 36 Male 10/1/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 5/25/2004 Male 11/20/2007 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/1/2006 Male 174 lb 1/24/2008 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/1/2007 Male 1/24/2008 Other Health Professional France
Primary
Secondary
Concomitant
Rectal Cancer Other Serious 9/20/2007 Male 171 lb 3/28/2008 United States
Primary
Concomitant
Haematoma Hospitalization 2/3/2008 Male 4/10/2008 Other Health Professional France
Primary
Secondary
Abortion Induced Other Serious 9/25/2007 31 Female 4/30/2008 United States
Primary
Secondary
Myocardial Infarction Other Serious 4/1/2008 54 Male 5/8/2008 Consumer United States
Primary
Concomitant
Pleural Effusion Hospitalization 3/7/2006 Male 5/28/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/7/2006 Male 6/3/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/1/2007 60 Male 6/10/2008 Other Health Professional United States
Primary
Secondary
Drug Exposure During Pregnancy Other Serious 5/30/2007 25 Female 6/17/2008 Physician
Primary
Secondary
Vomiting Hospitalization 7/1/2007 60 Male 6/20/2008 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 3/7/2006 Male 6/20/2008 United States
Primary
Secondary
Concomitant
Abortion Spontaneous Other Serious 5/30/2007 25 Female 6/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Hospitalization 7/1/2007 60 Male 6/24/2008 Other Health Professional United States
Primary
Secondary
Rash Other Serious 3/30/2008 Female 6/27/2008 Physician Spain
Primary
Concomitant
Lipodystrophy Acquired Other Serious 10/1/2007 21 Female 141 lb 7/3/2008 Other Health Professional United States
Primary
Secondary
Osteonecrosis Other Serious 54 Male 7/7/2008 Physician Austria
Primary
Concomitant
Viral Load Increased Other Serious 24 Female 7/11/2008 United States
Primary
Secondary
Respiratory Failure Death 7/14/2008 Male 7/30/2008 Physician Japan
Primary
Secondary
Meningitis Cryptococcal Hospitalization 7/19/2005 Male 8/4/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/7/2006 Male 8/5/2008 United States
Primary
Secondary
Concomitant
Panic Attack Hospitalization Female 8/6/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 3/30/2008 Female 8/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 3/31/2008 Female 8/22/2008 Physician France
Primary
Secondary
Concomitant
Myalgia Hospitalization 9/7/2001 Male 8/28/2008 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 7/1/2008 Male 9/4/2008 Other Health Professional France
Primary
Secondary
Ventricular Tachycardia Hospitalization 8/2/2008 Male 9/5/2008 Other Health Professional France
Primary
Secondary
Coronary Artery Occlusion Hospitalization 8/1/2008 Male 9/16/2008 Consumer United States
Primary
Concomitant
Angina Unstable Hospitalization 9/3/2008 48 Male 157 lb 9/16/2008 United States
Primary
Secondary
Concomitant
Coronary Artery Occlusion Hospitalization 8/1/2008 Male 9/19/2008 Consumer United States
Primary
Concomitant
Meningitis Cryptococcal Hospitalization 7/19/2005 Male 9/23/2008 Physician Japan
Primary
Secondary
Concomitant
Angina Unstable Hospitalization 9/3/2008 48 Male 157 lb 9/26/2008 United States
Primary
Secondary
Concomitant
Myalgia Hospitalization 9/7/2001 Male 10/2/2008 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/7/2006 Male 10/8/2008 United States
Primary
Secondary
Concomitant
Epistaxis Other Serious 10/7/2008 55 Male 161 lb 10/16/2008 United States
Primary
Secondary
Vomiting Hospitalization 3/7/2006 Male 10/21/2008 United States
Primary
Secondary
Concomitant
Respiratory Failure Death Male 10/28/2008 Consumer United States
Primary
Secondary
Glomerular Filtration Rate Decreased Other Serious 10/7/2008 55 Male 161 lb 10/28/2008 United States
Primary
Secondary
Concomitant
Meningitis Cryptococcal Hospitalization 7/19/2005 Male 11/7/2008 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 8/1/2008 44 Male 187 lb 11/20/2008 Physician United States
Primary
Concomitant
Chorioamnionitis Other Serious 10/25/2008 40 Female 11/21/2008 United States
Primary
Secondary
Stillbirth Other Serious 10/25/2008 40 Female 11/24/2008 United States
Primary
Secondary
Chorioamnionitis Other Serious 10/25/2008 40 Female 12/2/2008 United States
Primary
Secondary
Rash Other Serious 8/1/2008 44 Male 187 lb 12/2/2008 Physician United States
Primary
Concomitant
Haematoma Hospitalization 2/3/2008 Male 12/11/2008 Other Health Professional France
Primary
Secondary
Cerebral Haematoma Hospitalization 8/21/2008 Male 12/22/2008 Physician France
Primary
Secondary
Skin Swelling Other Serious Male 4 lb 12/22/2008 United States
Primary
Secondary
Renal Failure Chronic Life Threatening 7/11/2006 36 Male 12/23/2008 Physician Japan
Primary
Secondary
Concomitant
Urticaria Hospitalization 10/31/2008 20 Male 1/7/2009 United Kingdom
Primary
Secondary
Concomitant
Skin Swelling Other Serious Male 4 lb 1/13/2009 United States
Primary
Secondary
Skin Swelling Other Serious Male 4 lb 1/21/2009 United States
Primary
Secondary
Respiratory Failure Death Male 3/5/2009 Consumer United States
Primary
Secondary
Respiratory Failure Death Male 3/12/2009 Consumer United States
Primary
Secondary
Osteonecrosis Other Serious 46 Male 3/13/2009 United States
Primary
Secondary
Drug Resistance Other Serious 1/1/2007 Male 3/31/2009 Physician France
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 11/14/2007 Male 4/27/2009 Consumer Australia
Primary
Secondary
Vomiting Hospitalization 10/6/2007 56 Male 7/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea 44 Male 7/27/2009 United States
Primary
Secondary
Concomitant
Nausea 54 Male 7/27/2009 United States
Primary
Secondary
Nausea 51 Male 7/27/2009 United States
Primary
Secondary
Concomitant
Mycobacterium Avium Complex Infection Hospitalization 7/24/2008 44 Male 188 lb 8/7/2009 Physician United States
Primary
Secondary
Concomitant
Kaposi's Sarcoma Death 2/1/2009 28 Male 8/18/2009 Physician United Kingdom
Primary
Concomitant
Rectal Cancer Other Serious 9/20/2007 Male 171 lb 9/3/2009 Other Health Professional United States
Primary
Concomitant
Memory Impairment Other Serious 25 Male 9/3/2009 Physician United Kingdom
Primary
Secondary
Memory Impairment Other Serious 25 Male 9/14/2009 Physician United Kingdom
Primary
Secondary
Memory Impairment Other Serious 7/1/2009 25 Male 154 lb 9/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Myalgia Hospitalization 9/7/2001 Male 9/18/2009 Japan
Primary
Secondary
Concomitant
Pain Other Serious 6/4/2007 40 Male 9/18/2009 United Kingdom
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 9/1/2008 Male 9/23/2009 Japan
Primary
Secondary
Concomitant
Memory Impairment Other Serious 7/1/2009 25 Male 154 lb 9/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 9/1/2008 Male 10/5/2009 Japan
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 8/1/2009 22 Female 110 lb 10/6/2009 Physician Romania
Primary
Concomitant
Urticaria Hospitalization 10/31/2008 20 Male 11/2/2009 United Kingdom
Primary
Secondary
Concomitant
Mycobacterium Avium Complex Infection Hospitalization 7/24/2008 Male 188 lb 11/5/2009 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Malformation Congenital Anomaly 2/21/2009 11/11/2009 Consumer
Primary
Secondary
Gastrointestinal Malformation Life Threatening 2/21/2009 11/17/2009 Consumer
Primary
Secondary
Concomitant
Exomphalos Congenital Anomaly 2/21/2009 11/17/2009 United States
Primary
Secondary
Gastrointestinal Malformation Life Threatening 2/21/2009 11/21/2009 Other Health Professional
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 9/1/2008 Male 11/23/2009 Japan
Primary
Secondary
Concomitant
Gastrointestinal Malformation Life Threatening 2/21/2009 11/23/2009 Other Health Professional
Primary
Secondary
Concomitant
Exomphalos Congenital Anomaly 2/21/2009 11/23/2009 United States
Primary
Secondary
Vomiting Hospitalization 7/24/2008 Male 11/25/2009 United States
Primary
Concomitant
Myalgia Hospitalization 9/7/2001 Male 11/25/2009 Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Life Threatening 11/24/2009 Male 199 lb 12/2/2009 United States
Primary
Concomitant
Neutrophil Count Decreased Life Threatening 11/24/2009 Male 199 lb 12/3/2009 United States
Primary
Concomitant
Gastrointestinal Malformation Life Threatening 2/21/2009 12/5/2009 Other Health Professional
Primary
Secondary
Concomitant
Neutrophil Count Decreased Life Threatening 11/24/2009 Male 199 lb 12/8/2009 United States
Primary
Concomitant
Gastrointestinal Malformation Life Threatening 2/21/2009 12/15/2009 Other Health Professional
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/11/2009 Male 132 lb 12/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Life Threatening 11/24/2009 Male 199 lb 12/17/2009 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/11/2009 Male 132 lb 12/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Life Threatening 11/24/2009 Male 199 lb 12/30/2009 United States
Primary
Concomitant
Portal Hypertension Other Serious Male 1/5/2010 United Kingdom
Primary
Secondary
Gastrointestinal Malformation Life Threatening 2/21/2009 1/11/2010 Other Health Professional
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 9/1/2008 Male 1/12/2010 Japan
Primary
Secondary
Concomitant
Gastrointestinal Malformation Life Threatening 2/21/2009 1/13/2010 Other Health Professional
Primary
Secondary
Concomitant
Pain Other Serious 6/4/2007 40 Male 1/14/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pain Other Serious 6/4/2007 40 Male 1/14/2010 United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Decreased Life Threatening 11/24/2009 Male 199 lb 1/15/2010 United States
Primary
Concomitant
Gastrointestinal Malformation Life Threatening 2/21/2009 1/16/2010 Other Health Professional
Primary
Secondary
Concomitant
Abortion Induced Other Serious 9/14/2009 43 Female 1/20/2010 United States
Primary
Secondary
Gastrointestinal Malformation Life Threatening 2/21/2009 1/22/2010 Other Health Professional
Primary
Secondary
Concomitant
Gastrointestinal Malformation Life Threatening 2/21/2009 1/29/2010 Other Health Professional
Primary
Secondary
Concomitant
Small For Dates Baby Other Serious 9/29/2009 Male 5 lb 2/2/2010 United States
Primary
Secondary
Premature Labour Other Serious 2/21/2009 Female 163 lb 2/12/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Premature Labour Other Serious 2/21/2009 Female 163 lb 2/16/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Hospitalization 1/29/2010 46 Male 2/12/2010 Other Health Professional United States
Primary
Concomitant
Arthralgia Disability Male 3/3/2010 Physician France
Primary
Secondary
Osteonecrosis Other Serious 46 Male 3/5/2010 United States
Primary
Secondary
Premature Labour Other Serious 2/21/2009 Female 163 lb 3/9/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Pregnancy Congenital Anomaly 3/15/2010 United Kingdom
Primary
Secondary
Pain Other Serious 6/4/2007 40 Male 3/18/2010 United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 1/29/2010 46 Male 4/5/2010 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/5/2010 49 Female 132 lb 4/15/2010 Physician United Kingdom
Primary
Secondary
Pain Other Serious 6/4/2007 40 Male 4/28/2010 United Kingdom
Primary
Secondary
Concomitant
Pain Other Serious 6/4/2007 40 Male 5/7/2010 United Kingdom
Primary
Secondary
Concomitant
Ophthalmoplegia Other Serious 52 Male 5/11/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/14/2010 Other Health Professional United States
Primary
Secondary
Myocardial Infarction Other Serious 5/1/2008 53 Male 216 lb 5/18/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypoplasia Death 4/23/2010 Male 5/18/2010 United States
Primary
Secondary
Premature Rupture Of Membranes Other Serious 21 Female 5/20/2010 United States
Primary
Secondary
Myocardial Infarction Other Serious 5/1/2008 53 Male 216 lb 5/21/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Premature Rupture Of Membranes Other Serious 21 Female 5/25/2010 United States
Primary
Secondary
Chorioamnionitis Other Serious 10/25/2008 40 Female 5/28/2010 United States
Primary
Secondary

Drug Data