Darunavir combined with Isentress

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenia Other Serious Male 12/10/2007 Physician Portugal
Primary
Secondary
Renal Tubular Necrosis Hospitalization 10/30/2007 36 Male 2/7/2008 Physician France
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/4/2008 Male 2/1/2008 United Kingdom
Primary
Secondary
Vision Blurred Other Serious 12/1/2007 23 Female 2/1/2008 Netherlands
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 10/30/2007 36 Male 99 lb 2/18/2008 Physician France
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 10/30/2007 36 Male 99 lb 2/21/2008 Physician France
Primary
Concomitant
Liver Function Test Abnormal Other Serious 6/27/2007 44 Male 3/3/2008 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 10/30/2007 36 Male 99 lb 3/6/2008 Physician France
Primary
Concomitant
Rash Generalised 11/13/2007 46 Female 2/8/2008 Physician United States
Primary
Concomitant
Low Density Lipoprotein Increased 2/27/2007 54 Female 2/8/2008 United States
Primary
Concomitant
Rash Generalised Other Serious 11/13/2007 46 Female 156 lb 2/8/2008 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Other Serious 1/2/2008 52 Male 3/3/2008 France
Primary
Concomitant
Liver Function Test Abnormal Other Serious 6/27/2007 44 Male 3/19/2008 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 10/30/2007 36 Male 99 lb 3/26/2008 Physician France
Primary
Concomitant
Jaundice Life Threatening 12/1/2007 48 Male 3/27/2008 Other Health Professional France
Primary
Secondary
Concomitant
Jaundice Life Threatening 12/1/2007 48 Male 4/1/2008 Other Health Professional France
Primary
Secondary
Concomitant
Haematoma Hospitalization 2/3/2008 32 Male 4/10/2008 Other Health Professional France
Primary
Secondary
Weight Decreased Hospitalization 1/2/2008 41 Male 4/7/2008 United Kingdom
Primary
Secondary
Concomitant
Pruritus Hospitalization 1/1/2008 41 Male 4/10/2008 Physician Belgium
Primary
Concomitant
Rhabdomyolysis Hospitalization 4/1/2008 44 Female 4/21/2008 Physician France
Primary
Secondary
Haematoma Hospitalization 2/3/2008 32 Male 5/1/2008 Other Health Professional France
Primary
Secondary
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 7/1/2007 57 Male 185 lb 5/6/2008 Physician France
Primary
Concomitant
Myalgia Disability 8/31/2007 47 Male 5/7/2008 Other Health Professional France
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 4/9/2008 48 Male 5/8/2008 France
Primary
Secondary
Concomitant
Blood Triglycerides Increased Male 5/9/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/2/2008 41 Male 5/13/2008 United Kingdom
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 10/10/2007 56 Male 174 lb 5/19/2008 Physician Canada
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 5/28/2007 57 Male 185 lb 5/22/2008 Physician France
Primary
Concomitant
Post Procedural Complication Other Serious 10/9/2007 39 Male 5/16/2008 Physician France
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 9/25/2007 56 Male 174 lb 6/3/2008 Physician Canada
Primary
Concomitant
Hypokalaemia Hospitalization 4/9/2008 48 Male 6/5/2008 France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/1/2007 45 Male 6/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/1/2007 45 Male 6/25/2008 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/19/2008 59 Male 6/25/2008 Physician France
Primary
Secondary
Concomitant
Burkitt's Lymphoma Other Serious 12/28/2007 58 Male 7/10/2008 Physician United States
Primary
Concomitant
Burkitt's Lymphoma Other Serious 12/28/2007 58 Male 7/11/2008 Physician United States
Primary
Concomitant
Death Death 1/1/2008 46 Male 137 lb 7/14/2008 Pharmacist Canada
Primary
Concomitant
Myositis Other Serious 11/28/2007 52 Male 7/16/2008 Physician France
Primary
Secondary
Concomitant
Hepatitis B Death 1/1/2008 46 Male 137 lb 7/17/2008 Pharmacist Canada
Primary
Concomitant
Myositis Other Serious 11/28/2007 52 Male 7/18/2008 Physician France
Primary
Secondary
Concomitant
Pancreatitis Other Serious 7/1/2008 51 Female 112 lb 7/24/2008 Physician Switzerland
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 4/9/2008 48 Male 8/6/2008 France
Primary
Secondary
Concomitant
Panic Attack Hospitalization Female 8/6/2008 Other Health Professional United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 6/27/2007 44 Male 8/15/2008 United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 11/1/2007 65 Male 8/15/2008 Australia
Primary
Secondary
Flatulence 12/14/2007 34 Female 151 lb 8/8/2008 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 3/31/2008 Female 8/22/2008 Physician France
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 3/31/2008 44 Female 8/22/2008 Other Health Professional France
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 3/31/2008 44 Female 8/27/2008 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 8/2/2008 48 Male 8/28/2008 Other Health Professional France
Primary
Secondary
Liver Function Test Abnormal Other Serious 6/27/2007 44 Male 9/5/2008 United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/1/2007 45 Male 9/9/2008 Other Health Professional France
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 8/26/2008 42 Female 119 lb 9/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 9/16/2008 42 Female 10/2/2008 France
Primary
Secondary
Concomitant
Pericarditis Hospitalization 9/19/2008 20 Male 10/2/2008 Pharmacist Ireland
Primary
Concomitant
Vomiting Hospitalization 8/26/2008 42 Female 119 lb 9/29/2008 United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 9/16/2008 42 Female 10/7/2008 Other Health Professional France
Primary
Secondary
Concomitant
Urticaria Hospitalization 8/26/2008 42 Female 119 lb 10/3/2008 United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 9/16/2008 42 Female 10/10/2008 Other Health Professional France
Primary
Secondary
Concomitant
Neutropenia Hospitalization 9/16/2008 42 Female 10/21/2008 Other Health Professional France
Primary
Secondary
Concomitant
Myalgia Disability 8/31/2007 47 Male 10/22/2008 Other Health Professional France
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 10/7/2008 55 Male 161 lb 10/20/2008 United States
Primary
Secondary
Intra-uterine Death Death 10/25/2008 Male 10/30/2008 Physician France
Primary
Concomitant
Intra-uterine Death Death 10/25/2008 Male 11/5/2008 Physician France
Primary
Concomitant
Neutropenia Hospitalization 9/16/2008 42 Female 11/11/2008 Other Health Professional France
Primary
Secondary
Concomitant
Rash Other Serious 1/23/2008 39 Female 163 lb 11/12/2008 Physician United Kingdom
Primary
Concomitant
Neutropenia Hospitalization 9/16/2008 42 Female 11/19/2008 Other Health Professional France
Primary
Secondary
Concomitant
Rash Other Serious 8/1/2008 44 Male 187 lb 11/20/2008 Physician United States
Primary
Concomitant
Chorioamnionitis Other Serious 10/25/2008 40 Female 11/21/2008 United States
Primary
Secondary
Neutropenia Hospitalization 9/16/2008 42 Female 11/21/2008 Other Health Professional France
Primary
Secondary
Concomitant
Rash Hospitalization 2/1/2008 Female 11/10/2008 Physician United States
Primary
Concomitant
Chorioamnionitis Other Serious Female 11/26/2008 Physician United Kingdom
Primary
Secondary
Neutropenia Hospitalization 9/16/2008 42 Female 11/26/2008 Other Health Professional France
Primary
Secondary
Concomitant
Incorrect Dose Administered Other Serious 10/25/2008 40 Female 11/26/2008 Physician United Kingdom
Primary
Secondary
Chorioamnionitis Other Serious 10/25/2008 40 Female 12/2/2008 United States
Primary
Secondary
Rash Other Serious 8/1/2008 44 Male 187 lb 12/2/2008 Physician United States
Primary
Concomitant
Haematoma Hospitalization 2/3/2008 32 Male 12/4/2008 Other Health Professional France
Primary
Secondary
Rhabdomyolysis Hospitalization 3/31/2008 44 Female 12/8/2008 Other Health Professional France
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 3/31/2008 44 Female 12/8/2008 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/1/2008 60 Male 12/9/2008 Physician Spain
Primary
Secondary
Rhabdomyolysis Hospitalization 3/31/2008 44 Female 12/19/2008 Other Health Professional France
Primary
Secondary
Concomitant
Wegener's Granulomatosis Hospitalization 1/1/2008 45 Male 1/6/2009 Physician Germany
Primary
Concomitant
Thrombocytopenia Hospitalization 1/1/2008 48 Male 1/7/2009 Physician France
Primary
Concomitant
Thrombocytopenia Hospitalization 1/1/2008 48 Male 1/20/2009 Physician France
Primary
Concomitant
Vomiting Hospitalization 11/1/2008 60 Male 1/26/2009 Physician Spain
Primary
Secondary
Pruritus Hospitalization 12/14/2008 46 Male 1/27/2009 Other Health Professional France
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 12/1/2008 Male 2/9/2009 Physician Spain
Primary
Secondary
White Blood Cell Count Decreased 9/23/2008 Female 2/11/2009 United States
Primary
Secondary
Concomitant
Photopsia 1/1/2008 Male 2/11/2009 United States
Primary
Concomitant
Hypokalaemia Hospitalization 4/9/2008 48 Male 168 lb 3/2/2009 Physician France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/1/2007 45 Male 3/2/2009 Other Health Professional France
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 4/9/2008 48 Male 168 lb 3/4/2009 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/20/2008 58 Male 2/27/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 46 Male 3/13/2009 United States
Primary
Secondary
Hepatic Failure Other Serious 3/31/2009 Physician Canada
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 12/8/2008 39 Female 3/31/2009 Physician France
Primary
Concomitant
Hepatic Failure Other Serious 4/3/2009 Pharmacist Canada
Primary
Concomitant
Hepatic Failure Other Serious 3/19/2009 50 Male 4/6/2009 Pharmacist Canada
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 12/8/2008 39 Female 4/6/2009 Physician France
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 12/8/2008 39 Female 4/7/2009 Physician France
Primary
Concomitant
Lactic Acidosis Hospitalization 7/11/2008 42 Female 4/24/2009 Physician France
Primary
Concomitant
Metastases To Liver Hospitalization 7/11/2008 42 Female 4/27/2009 Physician France
Primary
Concomitant
Myositis Other Serious 11/28/2007 52 Male 4/27/2009 Physician France
Primary
Concomitant
Psychotic Disorder Other Serious Female 5/4/2009 Physician Spain
Primary
Concomitant
Palpitations Hospitalization 1/1/2008 Male 5/7/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure 9/23/2008 67 Female 198 lb 5/12/2009 Physician United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 2/8/2009 49 Female 247 lb 5/22/2009 Pharmacist United Kingdom
Primary
Concomitant
Neurotoxicity 4/29/2009 73 Male 130 lb 5/27/2009 Physician United States
Primary
Concomitant
Stevens-johnson Syndrome Death 2/8/2009 49 Female 247 lb 5/29/2009 Pharmacist United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 49 Female 247 lb 6/2/2009 Pharmacist United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 3/1/2008 45 Male 6/4/2009 Physician Canada
Primary
Concomitant
Suicidal Ideation Other Serious 3/1/2008 45 Male 6/5/2009 Physician Canada
Primary
Concomitant
Hepatitis C Other Serious 3/1/2009 50 Male 6/5/2009 Pharmacist Canada
Primary
Concomitant
Myositis Other Serious 1/2/2008 52 Male 6/12/2009 Physician France
Primary
Concomitant
Visual Impairment Hospitalization 49 Female 247 lb 6/19/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Drug Toxicity Death 4/1/2009 Female 6/26/2009 Physician United Kingdom
Primary
Concomitant
Respiratory Disorder Hospitalization 50 Female 6/26/2009 Physician United States
Primary
Concomitant
Visual Impairment Hospitalization 2/8/2009 49 Female 247 lb 7/1/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Hypercholesterolaemia Hospitalization 11/7/2008 54 Male 7/7/2009 Other Health Professional France
Primary
Secondary
Drug Toxicity Death 4/1/2009 Female 7/9/2009 Physician United Kingdom
Primary
Concomitant
Prostate Cancer Other Serious 9/25/2007 56 Male 174 lb 7/15/2009 Physician Canada
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 12/8/2008 27 Female 7/17/2009 Other Health Professional France
Primary
Secondary
Nausea 44 Male 7/27/2009 United States
Primary
Secondary
Concomitant
Nausea 51 Male 7/27/2009 United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 3/3/2009 49 Female 247 lb 8/18/2009 Physician United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 2/8/2009 49 Female 247 lb 8/19/2009 Physician United Kingdom
Primary
Concomitant
Lymphadenopathy 6/12/2009 40 Male 8/6/2009 Physician United States
Primary
Concomitant
Weight Increased 8/6/2009 Physician United States
Primary
Concomitant
Myositis Disability 1/1/2009 9/2/2009 Physician Canada
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 12/8/2008 29 Female 9/4/2009 Other Health Professional France
Primary
Secondary
Mesenteric Vein Thrombosis Hospitalization 5/22/2009 46 Male 9/2/2009 Brazil
Primary
Secondary
Concomitant
Mesenteric Vein Thrombosis Hospitalization 5/22/2009 46 Male 9/8/2009 Brazil
Primary
Secondary
Concomitant
Metastases To Liver Hospitalization 7/11/2008 42 Female 9/24/2009 Physician France
Primary
Concomitant
Osteonecrosis Hospitalization 8/1/2009 22 Female 110 lb 10/6/2009 Physician Romania
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 1/1/2009 40 Female 10/13/2009 Consumer Brazil
Primary
Secondary
Concomitant
Nephropathy Toxic Disability 7/1/2009 50 Male 10/12/2009 Physician United States
Primary
Concomitant
Hepatitis Toxic Other Serious 6/16/2009 43 Male 10/21/2009 Other Health Professional Spain
Primary
Secondary
Lung Squamous Cell Carcinoma Stage Unspecified Other Serious 9/24/2008 43 Male 11/3/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Other Serious 9/24/2008 43 Male 11/6/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Weight Decreased Disability 1/1/2009 40 Male 11/12/2009 Physician Colombia
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 12/8/2008 29 Female 11/17/2009 Other Health Professional France
Primary
Secondary
Rash Other Serious 8/1/2009 56 Male 128 lb 11/18/2009 Physician United States
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 12/8/2008 29 Female 11/19/2009 Other Health Professional France
Primary
Secondary
Psychomotor Hyperactivity Hospitalization 11/1/2009 Male 11/20/2009 Physician Spain
Primary
Concomitant
Exomphalos Congenital Anomaly 2/21/2009 11/23/2009 Physician United Kingdom
Primary
Concomitant
Nausea Life Threatening 9/21/2009 42 Female 11/10/2009 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 12/8/2008 29 Female 11/25/2009 Other Health Professional France
Primary
Secondary
Vomiting Other Serious 10/29/2009 57 Male 11/18/2009 Germany
Primary
Secondary
Concomitant
Osteomyelitis Other Serious Unknown 11/20/2009 Physician France
Primary
Secondary
Lichenoid Keratosis Hospitalization 3/17/2008 43 Male 12/14/2009 Consumer France
Primary
Concomitant

Drug Data