Dapsone combined with Fluconazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 1/17/2006 United States
Primary
Concomitant
Drug Ineffective Other Serious 12/1/2005 49 Female 132 lb 1/17/2006 Physician United States
Primary
Concomitant
Synostosis Other Serious 0 Male 7 lb 2/6/2006 Physician Canada
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Subdural Haematoma Life Threatening 11/8/2005 43 Male 172 lb 2/22/2006 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/23/2006 United States
Primary
Concomitant
Pneumonia Life Threatening 4/21/2003 Male 2/23/2006 Physician Japan
Primary
Concomitant
Neutropenia Hospitalization 1/1/2004 48 Male 3/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Other Serious 31 Male 3/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 2/1/2006 27 Female 106 lb 3/14/2006 United Kingdom
Primary
Concomitant
Subdural Haematoma Life Threatening 11/8/2005 43 Male 172 lb 4/14/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/17/2006 Male 155 lb 4/20/2006 Pharmacist United States
Primary
Secondary
Concomitant
Urine Output Increased Other Serious 12/1/2005 49 Female 132 lb 4/27/2006 Physician United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/19/2006 5 Male 40 lb 4/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 11/12/1997 49 Female 5/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 4/19/2006 5 Male 40 lb 5/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Virus Urine Test Positive Hospitalization 4/19/2006 5 Male 40 lb 5/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Pruritic Other Serious 50 Male 6/2/2006 Canada
Primary
Concomitant
Interacting
Ventricular Tachycardia Other Serious 11/19/1997 50 Male 5/26/2006 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 35 Male 6/8/2006
Primary
Secondary
Concomitant
Tachycardia Other Serious 35 Male 6/19/2006 United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 50 Male 7/20/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Hyperbilirubinaemia Required Intervention 10/25/2005 36 Female 11/29/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 8/1/2006 37 Male 9/15/2006 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 6/23/2005 Female 148 lb 10/19/2006 Ireland
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 10/12/2006 46 Male 186 lb 12/7/2006 Pharmacist United States
Primary
Concomitant
Tremor Hospitalization 24 Female 1/5/2007 United States
Primary
Secondary
Neutropenia Other Serious 1/1/2004 Male 1/25/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Hypersensitivity Other Serious 1/1/2007 26 Male 118 lb 2/7/2007 United States
Primary
Secondary
Concomitant
Rash Other Serious 11/1/2006 31 Male 169 lb 1/15/2007 Pharmacist United States
Primary
Concomitant
Transplant Rejection Hospitalization 12/28/2006 50 Female 110 lb 2/8/2007 Physician United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 2/26/2007 65 Male 137 lb 3/7/2007 Other Health Professional Ireland
Primary
Secondary
Concomitant
Pyrexia Other Serious 9/12/2006 Male 214 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 3/1/2007 Male 156 lb 3/27/2007 Physician United States
Primary
Concomitant
Stomatitis Hospitalization 2/26/2007 65 Male 137 lb 3/20/2007 Other Health Professional Ireland
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 3/1/2007 Male 156 lb 4/17/2007 Physician United States
Primary
Concomitant
Hodgkin's Disease Hospitalization 3/28/2007 Male 93 lb 4/20/2007 Physician United States
Primary
Secondary
Concomitant
Hodgkin's Disease Hospitalization 3/28/2007 Male 93 lb 5/2/2007 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 10/17/2004 Male 5/17/2007 United States
Primary
Concomitant
Renal Impairment Hospitalization 10/17/2004 Male 5/30/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/9/2007 19 Male 164 lb 5/24/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 4/9/2007 19 Male 167 lb 6/4/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/9/2007 19 Male 167 lb 6/7/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 50 Male 6/15/2007 Canada
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/3/2007 8 Female 43 lb 6/20/2007 Physician United States
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 33 Male 7/23/2007 Physician United States
Primary
Concomitant
Sinus Bradycardia Hospitalization 1/29/2007 26 Male 108 lb 8/20/2007 United States
Primary
Concomitant
Meningitis Cryptococcal Hospitalization 8/18/1992 Male 367 lb 7/24/2007 Physician United States
Primary
Concomitant
Septic Shock Hospitalization 8/19/2007 45 Male 9/4/2007 Physician Malaysia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/3/2007 8 Female 43 lb 8/29/2007 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/16/2007 44 Female 9/6/2007 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 7/16/2007 44 Female 10/19/2007 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Other Serious 7/30/2007 66 Male 154 lb 10/24/2007 Consumer United Kingdom
Primary
Concomitant
Pleural Effusion Other Serious 7/30/2007 66 Male 154 lb 10/30/2007 Consumer United Kingdom
Primary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Drug Hypersensitivity Other Serious 1/1/2007 26 Male 118 lb 12/7/2007 United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2003 43 Male 170 lb 1/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2003 43 Male 170 lb 2/22/2008 Physician United States
Primary
Secondary
Concomitant
T-lymphocyte Count Decreased Other Serious 1/1/2004 47 Male 173 lb 3/18/2008 Consumer United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/18/2008 United States
Primary
Concomitant
Myocardial Ischaemia Life Threatening 8/30/2005 Male 139 lb 4/22/2008 United States
Primary
Concomitant
T-lymphocyte Count Decreased Other Serious 1/1/2004 47 Male 173 lb 4/28/2008 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 4/13/2008 51 Male 234 lb 4/22/2008 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/30/2008 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 5/9/2008 United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 4/13/2008 51 Male 234 lb 5/8/2008 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 5/15/2008 United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 3/21/2008 50 Male 234 lb 5/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 6/23/2005 Female 148 lb 6/6/2008 Ireland
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 Female 182 lb 6/17/2008 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/30/2005 Male 139 lb 6/27/2008 United States
Primary
Concomitant
Ultrasound Bladder Abnormal Hospitalization 4/19/2006 5 Male 40 lb 6/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 Female 182 lb 7/10/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2007 Female 88 lb 7/10/2008 Physician United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 46 Female 8/5/2008 Physician United States
Primary
Concomitant
Interacting
Therapeutic Agent Toxicity Life Threatening 46 Female 7/28/2008 Physician United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 46 Female 8/13/2008 United States
Primary
Concomitant
Interacting
Sepsis Hospitalization 8/6/2007 43 Male 8/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Creatinine Increased Required Intervention 5/6/2008 41 Male 167 lb 6/13/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 46 Female 8/21/2008 United States
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 8/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 46 Female 9/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 46 Female 9/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 9/22/2005 19 Male 179 lb 9/26/2008 Physician United States
Primary
Concomitant
Serotonin Syndrome Other Serious 46 Female 9/26/2008 United States
Primary
Concomitant
Interacting
Stem Cell Transplant Hospitalization 46 Female 9/24/2008 Physician United States
Primary
Secondary
Concomitant
Confusional State 46 Female 10/2/2008 United States
Primary
Concomitant
Ventricular Tachycardia Required Intervention 4/12/2007 19 Male 165 lb 10/10/2008 Physician United States
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 1/1/2008 46 Female 10/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 10/7/2008 55 Male 161 lb 10/28/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/31/2008 8 Female 71 lb 10/30/2008 Physician United States
Primary
Concomitant
Stem Cell Transplant Life Threatening 46 Female 11/11/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cells Urine Positive Other Serious 10/7/2008 55 Male 161 lb 11/13/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Required Intervention 4/12/2007 19 Male 165 lb 11/18/2008 Physician United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 46 Female 12/4/2008
Primary
Secondary
Concomitant
Mental Status Changes Other Serious 8/1/2006 37 Male 150 lb 12/10/2008 Physician United States
Primary
Secondary
Concomitant
Mental Status Changes Other Serious 8/1/2006 37 Male 150 lb 12/17/2008 United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/22/2005 19 Male 179 lb 12/30/2008 Physician United States
Primary
Concomitant
Stem Cell Transplant Hospitalization 46 Female 1/22/2009 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/2/2008 Male 165 lb 2/10/2009 Physician Australia
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/2/2008 Male 2/19/2009 Australia
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/2/2008 45 Male 2/16/2009 Physician Australia
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/2/2008 Male 165 lb 2/24/2009 Physician Australia
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/2/2008 Male 3/4/2009 Australia
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/2/2008 45 Male 2/26/2009 Australia
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/2/2008 45 Male 3/2/2009 Physician Australia
Primary
Secondary
Concomitant
Sepsis Other Serious 55 Male 3/16/2009
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 46 Female 4/24/2009 Other Health Professional United States
Primary
Concomitant
Bone Marrow Failure Required Intervention 11/1/2008 Female 160 lb 1/25/2009 Pharmacist United States
Primary
Concomitant
Oesophageal Candidiasis Hospitalization 4/12/2005 Male 131 lb 5/26/2009 Other Health Professional United States
Primary
Concomitant
Serum Sickness Other Serious 4/30/2007 24 Female 194 lb 5/28/2009 Physician United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 7/28/2008 27 Male 121 lb 11/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/10/2009 Female 6/30/2009 Other Health Professional United States
Primary
Concomitant
Ovarian Cancer Other Serious 1/1/2009 Female 6/30/2009 Other Health Professional United States
Primary
Concomitant
Headache Hospitalization 4/4/2006 Male 7/1/2009 Physician United States
Primary
Concomitant
Hodgkin's Disease Hospitalization 3/28/2007 Male 7/1/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 11/1/2004 Male 7/1/2009 Physician United States
Primary
Concomitant
Anaemia Hospitalization 2/8/2007 Male 7/1/2009 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 8/16/2006 Male 7/1/2009 Physician United States
Primary
Concomitant
Perforated Ulcer Hospitalization 8/25/2005 Male 7/1/2009 Physician United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 5/3/2006 Female 7/1/2009 Physician United States
Primary
Secondary
Concomitant
Hepatorenal Failure Other Serious Female 7/7/2009 Physician United States
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Other Serious 1/1/2009 Female 7/10/2009 Physician United States
Primary
Concomitant
Lung Neoplasm Hospitalization 5/16/2005 Male 139 lb 7/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 5/1/2009 39 Female 172 lb 7/20/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/10/2009 Female 7/24/2009 Other Health Professional United States
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 1/1/2009 Female 7/24/2009 Physician United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 7/24/2009 50 Male 160 lb 7/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 4/20/2005 44 Male 184 lb 8/13/2009 United States
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 5/1/2009 39 Female 172 lb 8/17/2009 Physician United States
Primary
Secondary
Concomitant
Hepatorenal Failure Other Serious Female 8/20/2009 Physician United States
Primary
Secondary
Concomitant
Tachypnoea Other Serious 7/22/2009 21 Male 104 lb 8/17/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 7/22/2009 Male 104 lb 9/11/2009 Physician United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 8/30/2009 Female 133 lb 9/11/2009 Physician United States
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 46 Female 9/9/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 7/22/2009 Male 104 lb 9/21/2009 Physician United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 8/13/2009 Female 133 lb 9/25/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 7/22/2009 Male 104 lb 9/25/2009 Physician United States
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Other Serious 1/1/2009 Female 10/16/2009 Physician United States
Primary
Concomitant
Temporomandibular Joint Syndrome Required Intervention 9/15/2009 17 Male 161 lb 10/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Death 9/12/2009 33 Female 95 lb 10/27/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Life Threatening 7/22/2009 Male 104 lb 11/5/2009 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Required Intervention 9/15/2009 17 Male 161 lb 10/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 8/13/2009 Female 133 lb 11/11/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 7/22/2009 Male 104 lb 11/16/2009 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Required Intervention 9/15/2009 17 Male 161 lb 11/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/8/2009 48 Female 115 lb 1/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 5/1/2009 39 Female 172 lb 1/27/2010 Physician United States
Primary
Secondary
Concomitant
Viral Test Positive Hospitalization 4/19/2006 5 Male 40 lb 2/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data