Danazol combined with Nplate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Oedema Peripheral Hospitalization 9/29/2008 Male 11/21/2008 Consumer United States
Primary
Concomitant
Platelet Count Decreased Other Serious 1/1/2009 Male 2/12/2009 Consumer United States
Primary
Concomitant
Acute Myeloid Leukaemia Death 11/6/2008 Female 2/26/2009 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 1/1/2009 Male 172 lb 2/26/2009 Other Health Professional United States
Primary
Concomitant
Tic Other Serious Male 3/13/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious Male 3/16/2009 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 9/29/2008 Male 3/19/2009 Physician United States
Primary
Concomitant
Pulmonary Haemorrhage Other Serious 12/11/2008 Female 3/19/2009 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 9/29/2008 Male 3/26/2009 Physician United States
Primary
Concomitant
Cognitive Disorder Female 3/26/2009 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 9/29/2008 Male 4/1/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Life Threatening 1/29/2009 Female 4/2/2009 Physician United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 4/16/2009 Male 5/1/2009 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/26/2009 Male 5/15/2009 Physician United States
Primary
Concomitant
Haematological Malignancy Death 4/16/2009 Male 5/19/2009 Physician United States
Primary
Concomitant
Death Death Male 5/19/2009 Physician United States
Primary
Concomitant
Myelodysplastic Syndrome Death 4/16/2009 Male 5/20/2009 Physician United States
Primary
Concomitant
Disease Progression Death 4/16/2009 Male 182 lb 6/19/2009 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 8/5/2009 Male 132 lb 8/20/2009 Pharmacist United States
Primary
Secondary
Concomitant
Death Death Male 126 lb 9/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 12/24/2008 Female 9/3/2009 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization Male 178 lb 9/4/2009 Physician United States
Primary
Concomitant
Death Death 10/11/2008 Female 9/10/2009 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/26/2009 Male 165 lb 10/7/2009 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/26/2009 Male 165 lb 11/24/2009 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 12/24/2008 Female 148 lb 1/7/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 Male 1/27/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 2/27/2009 Male 162 lb 2/11/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2009 Male 2/12/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Male 178 lb 2/19/2010 Physician United States
Primary
Secondary
Concomitant
Tic Other Serious Male 2/23/2010 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/2009 Female 133 lb 3/17/2010 Physician United States
Primary
Concomitant
Death Death Male 3/19/2010 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 1/1/2009 Male 172 lb 3/22/2010 Other Health Professional United States
Primary
Concomitant
Haemorrhage Intracranial Hospitalization 2/16/2009 67 Male 196 lb 4/1/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Male 4/1/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Male 4/2/2010 Physician United States
Primary
Concomitant
Pulmonary Embolism Other Serious 2/3/2009 54 Female 246 lb 4/6/2010 Physician United States
Primary
Concomitant
Haemorrhage Intracranial Hospitalization 2/16/2009 67 Male 196 lb 4/15/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious Male 4/15/2010 Physician United States
Primary
Concomitant
Skin Reaction Other Serious 3/3/2010 25 Male 4/19/2010 Physician Portugal
Primary
Concomitant
Pyrexia Other Serious 12/3/2008 72 Male 194 lb 4/21/2010 Physician United States
Primary
Concomitant
Post Procedural Infection Death 6/1/2009 68 Male 4/21/2010 Physician United States
Primary
Concomitant
Death Death Male 4/21/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 9/10/2009 67 Female 4/22/2010 Physician United States
Primary
Concomitant
Sepsis Other Serious Female 4/22/2010 Physician United States
Primary
Concomitant
Red Blood Cell Schistocytes Present Other Serious Female 4/23/2010 Physician United States
Primary
Concomitant
Death Death Male 4/23/2010 Physician United States
Primary
Concomitant
Bone Marrow Disorder Other Serious Male 4/23/2010 Physician United States
Primary
Concomitant
Death Other Serious Female 4/27/2010 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 6/22/2009 87 Female 4/29/2010 Physician United States
Primary
Concomitant
Bone Marrow Disorder Other Serious Male 5/3/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 4/20/2009 68 Female 5/3/2010 Physician United States
Primary
Concomitant
Death Death Female 5/5/2010 Physician United States
Primary
Concomitant
Red Blood Cell Schistocytes Present Other Serious 2/12/2010 48 Female 164 lb 5/5/2010 Physician United States
Primary
Concomitant
Procedural Pain Other Serious 9/5/2009 67 Female 5/5/2010 Physician United States
Primary
Concomitant
Skin Reaction Other Serious 3/3/2010 25 Male 5/6/2010 Physician Portugal
Primary
Concomitant
Transient Ischaemic Attack Other Serious 6/22/2009 87 Female 5/6/2010 Physician United States
Primary
Concomitant
Red Blood Cell Schistocytes Present Other Serious 2/12/2010 48 Female 164 lb 5/7/2010 Physician United States
Primary
Concomitant
Red Blood Cell Schistocytes Present Other Serious 2/12/2010 48 Female 164 lb 5/13/2010 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 6/17/2009 87 Female 163 lb 5/19/2010 Physician United States
Primary
Concomitant
Haematological Malignancy Other Serious Female 5/20/2010 Physician United States
Primary
Concomitant
Hypertension Other Serious 3/1/2009 83 Male 205 lb 5/21/2010 Physician United States
Primary
Concomitant
Death Death Female 5/21/2010 Physician United States
Primary
Concomitant
Economic Problem Other Serious Male 5/25/2010 Physician United States
Primary
Concomitant
Neoplasm Malignant Death Male 5/27/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2009 87 Female 163 lb 6/8/2010 Physician United States
Primary
Concomitant
Vasculitic Rash Other Serious 1/1/2009 53 Male 225 lb 6/21/2010 Physician United States
Primary
Concomitant
Death Death Male 6/24/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Death 1/1/2010 58 Male 190 lb 6/30/2010 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious Female 6/30/2010 Physician United States
Primary
Concomitant
Cardiac Arrest Death 3/23/2010 43 Female 7/7/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Male 7/8/2010 Physician United States
Primary
Concomitant
Death Death Male 7/9/2010 Physician United States
Primary
Concomitant
Death Death Female 7/12/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 12/1/2008 67 Male 7/13/2010 Physician United States
Primary
Concomitant
Death Death Male 7/14/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Female 7/16/2010 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 1/1/2009 62 Male 172 lb 7/16/2010 Other Health Professional United States
Primary
Concomitant
Skin Reaction Other Serious 3/3/2010 25 Male 7/20/2010 Physician Portugal
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious 12/24/2009 63 Female 370 lb 7/20/2010 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Death Male 172 lb 7/21/2010 Physician United States
Primary
Concomitant
Death Death Female 7/27/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 56 Female 7/28/2010 Physician United States
Primary
Concomitant
Cardiac Arrest Death Male 8/11/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2009 87 Female 163 lb 8/18/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 4/11/2010 50 Male 178 lb 8/23/2010 Physician United States
Primary
Secondary
Concomitant
Economic Problem Other Serious 1/1/2009 77 Male 8/26/2010 Physician United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2009 64 Male 8/26/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 9/24/2009 67 Female 8/27/2010 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 12/24/2009 63 Female 370 lb 8/27/2010 Physician United States
Primary
Concomitant
Death Death Female 8/27/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 12/1/2008 60 Male 156 lb 8/30/2010 Physician United States
Primary
Concomitant
Splenectomy Other Serious 1/1/2009 35 Male 8/31/2010 Physician United States
Primary
Concomitant
Platelet Count Increased Other Serious 1/5/2009 79 Male 9/14/2010 Physician United States
Primary
Concomitant
Thrombocytosis Other Serious 1/1/2009 86 Male 176 lb 9/15/2010 Physician United States
Primary
Concomitant
Death Death Female 9/16/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Death 1/1/2010 58 Male 190 lb 9/17/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2009 63 Male 9/21/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 73 Male 9/27/2010 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 10/6/2009 58 Female 9/30/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2009 63 Male 9/30/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious Male 10/4/2010 Physician United States
Primary
Concomitant
Vasculitic Rash Other Serious 1/1/2009 53 Male 225 lb 10/8/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Male 10/8/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2009 63 Male 10/8/2010 Physician United States
Primary
Concomitant
Splenectomy Other Serious 1/1/2010 14 Female 10/13/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2010 10/18/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 10/25/2010 Other Health Professional United States
Primary
Concomitant
Cerebral Haemorrhage Death 11/2/2010 Physician United States
Primary
Concomitant
Renal Failure Chronic Other Serious 1/1/2010 11/3/2010 Other Health Professional United States
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Other Serious 1/1/2010 11/4/2010 Pharmacist United States
Primary
Concomitant
Pain In Extremity Other Serious 9/29/2010 11/5/2010 Pharmacist United States
Primary
Concomitant
Colon Cancer Other Serious 11/5/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis Hospitalization 11/10/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2008 11/11/2010 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 5/3/2010 11/12/2010 Other Health Professional United States
Primary
Concomitant
Viith Nerve Paralysis Other Serious 5/3/2010 11/12/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Other Serious 1/1/2010 11/15/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/12/2010 Physician United States
Primary
Concomitant
Viith Nerve Paralysis Other Serious 5/3/2010 11/15/2010 Other Health Professional United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/2009 11/15/2010 Physician United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 6/1/2010 11/17/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/6/2010 11/22/2010 Other Health Professional United States
Primary
Concomitant
Death Death 11/23/2010 Physician United States
Primary
Concomitant
Viith Nerve Paralysis Other Serious 5/3/2010 11/23/2010 Other Health Professional United States
Primary
Concomitant
Lung Cancer Metastatic Other Serious 11/23/2010 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/2009 11/29/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 7/19/2010 11/30/2010 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Other Serious 11/30/2010 Physician United States
Primary
Concomitant
Normochromic Normocytic Anaemia Other Serious 1/1/2008 11/30/2010 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2010 11/30/2010 Physician United States
Primary
Concomitant
Waldenstrom's Macroglobulinaemia Other Serious 1/1/2008 12/6/2010 Physician United States
Primary
Concomitant
Death Death 12/7/2010 Physician United States
Primary
Concomitant
Death Death 8/6/2010 12/10/2010 Physician United States
Primary
Concomitant
Death Death 10/24/2010 12/16/2010 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Other Serious 12/20/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2010 12/21/2010 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 10/1/2010 12/22/2010 Physician United States
Primary
Concomitant
Death Death 1/1/2010 12/23/2010 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 10/1/2010 12/25/2010 Physician United States
Primary
Concomitant
Completed Suicide Death 1/1/2010 12/28/2010 Physician Germany
Primary
Concomitant
Bone Marrow Reticulin Fibrosis Other Serious 1/1/2010 12/30/2010 Physician United States
Primary
Concomitant
Evans Syndrome Other Serious 1/1/2010 12/30/2010 Physician United States
Primary
Concomitant
Bone Marrow Reticulin Fibrosis Other Serious 1/1/2010 1/7/2011 Physician United States
Primary
Concomitant
Angioedema Other Serious 1/1/2010 1/10/2011 Physician United States
Primary
Concomitant
Hospitalisation Hospitalization 12/21/2010 1/10/2011 Other Health Professional United States
Primary
Concomitant
Localised Oedema Other Serious 1/1/2010 1/11/2011 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 12/1/2010 1/12/2011 Physician United States
Primary
Concomitant
Angiogram Other Serious 5/1/2010 1/13/2011 Other Health Professional United States
Primary
Concomitant

Drug Data