Cytarabine combined with Mesna

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tongue Disorder Other Serious 12/5/2005 Male 216 lb 12/27/2005 United States
Primary
Secondary
Neurotoxicity Death 36 Female 1/5/2006 Physician Turkey
Primary
Secondary
Concomitant
Respiratory Failure Death 7/13/2005 57 Female 159 lb 1/13/2006 Physician Germany
Primary
Concomitant
Swelling Death 36 Female 1/31/2006 Physician Turkey
Primary
Secondary
Swelling Death 36 Female 2/13/2006 Physician Turkey
Primary
Secondary
Therapy Non-responder Death 36 Female 2/14/2006 Physician Turkey
Primary
Secondary
Staphylococcal Infection Hospitalization 11/23/2005 Male 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 3/6/2006 Female 111 lb 3/15/2006 United States
Primary
Secondary
T-cell Lymphoma Hospitalization 36 Female 3/17/2006 Physician Turkey
Primary
Secondary
Rash Generalised Hospitalization 1/13/2006 59 Female 3/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
Performance Status Decreased Other Serious 3/13/2006 Male 216 lb 3/29/2006 United States
Primary
Secondary
Stem Cell Transplant Hospitalization 1/13/2006 59 Female 4/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 4/18/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Required Intervention 4/11/2006 Female 4/13/2006 United States
Primary
Secondary
Vomiting Hospitalization 4/11/2006 Female 214 lb 4/28/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Life Threatening 4/7/2006 70 Female 5/12/2006 United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 36 Female 7/14/2006 Other Health Professional Turkey
Primary
Secondary
Tachycardia Hospitalization 3/4/2006 Male 311 lb 8/11/2006 United States
Primary
Secondary
Pancreatitis Acute Other Serious 10/11/2006 65 Male 196 lb 11/3/2006 Physician Australia
Primary
Secondary
Pancreatitis Acute Other Serious 10/11/2006 65 Male 196 lb 12/7/2006 Physician Australia
Primary
Secondary
Vith Nerve Paralysis Other Serious 10/22/2006 23 Male 172 lb 1/10/2007 Physician Finland
Primary
Secondary
Concomitant
Thrombocytopenia 1/1/2006 31 Male 3/28/2007 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 4/19/2007 Male 198 lb 5/8/2007 United States
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 36 Female 5/25/2007 Physician Turkey
Primary
Secondary
Tachycardia Hospitalization 6/3/2007 Male 188 lb 6/8/2007 United States
Primary
Secondary
Wound Abscess Hospitalization 6/6/2007 Male 45 lb 6/21/2007 United States
Primary
Secondary
Vith Nerve Paralysis Other Serious 10/22/2006 23 Male 172 lb 7/9/2007 United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/18/2007 Female 141 lb 7/20/2007 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/25/2007 Male 187 lb 7/30/2007 United States
Primary
Secondary
Premature Baby Other Serious Male 9/14/2007 Consumer United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 21 Female 8/16/2007 Physician United States
Primary
Secondary
Sepsis Neonatal Hospitalization Male 8/16/2007 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Death 54 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 61 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 79 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Lung Infiltration Death 7/13/2005 Female 159 lb 10/19/2007 Consumer France
Primary
Secondary
Concomitant
Vomiting Other Serious 11/11/2007 Male 289 lb 12/4/2007 United States
Primary
Secondary
Lung Infection Pseudomonal Other Serious 1/18/2007 57 Female 12/17/2007 Consumer United States
Primary
Secondary
Tachycardia Hospitalization 12/21/2007 Male 289 lb 1/7/2008 United States
Primary
Secondary
Venoocclusive Liver Disease Death Male 1/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 2/7/2008 Male 190 lb 2/12/2008 United States
Primary
Secondary
Treatment Noncompliance Hospitalization 2/19/2008 Male 187 lb 2/28/2008 United States
Primary
Secondary
Petechiae Other Serious 7/23/2007 Female 179 lb 3/10/2008 Physician Germany
Primary
Concomitant
Generalised Erythema Other Serious 11/14/2007 Female 132 lb 3/10/2008 Physician Germany
Primary
Concomitant
Thrombocytopenia 1/1/2006 31 Male 3/28/2008 Physician United States
Primary
Concomitant
Ventricular Fibrillation Death 1/1/2008 Male 4/10/2008 Other Health Professional France
Primary
Secondary
Concomitant
Neutropenic Sepsis Other Serious 4/16/2008 52 Male 157 lb 5/21/2008 Physician Malaysia
Primary
Concomitant
Ureteric Dilatation Other Serious 14 Male 5/21/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 14 Male 6/12/2008 Consumer United States
Primary
Secondary
Concomitant
Haematuria Other Serious 14 Male 6/12/2008 United Kingdom
Primary
Secondary
Concomitant
Haematuria Other Serious 1/1/2008 14 Male 6/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Telangiectasia Other Serious 14 Male 6/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nocturia Life Threatening 14 Male 6/16/2008 United Kingdom
Primary
Secondary
Concomitant
Haematuria Other Serious 14 Male 6/26/2008 United Kingdom
Primary
Concomitant
Pancreatitis Acute Hospitalization 5/14/2008 Male 7/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2007 37 Male 7/29/2008 India
Primary
Secondary
Concomitant
Malabsorption 7/28/2008 Male 125 lb 7/28/2008 United States
Primary
Secondary
Vasculitis Hospitalization 1/13/2006 59 Female 8/5/2008 France
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 8/5/2008 Female 136 lb 8/18/2008 United States
Primary
Secondary
Wound Infection Bacterial Hospitalization 5/27/2007 Female 141 lb 6/20/2007 United States
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Life Threatening 8/1/2000 34 Female 130 lb 10/10/2008 Physician United States
Primary
Secondary
Pulmonary Haemorrhage Death 10/13/2008 Physician United Kingdom
Primary
Secondary
Death Other Serious 10/13/2008 Physician United Kingdom
Primary
Secondary
Renal Failure Other Serious 10/13/2008 Physician United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 10/13/2008 Physician United Kingdom
Primary
Secondary
Neutropenic Sepsis Death 10/13/2008 Physician United Kingdom
Primary
Secondary
Pancreatitis Other Serious 10/13/2008 Physician United Kingdom
Primary
Secondary
Neurotoxicity Other Serious 10/13/2008 Physician United Kingdom
Primary
Secondary
Urine Leukocyte Esterase Positive Hospitalization 10/5/2008 Male 209 lb 10/9/2008 United States
Primary
Secondary
Renal Failure Acute Hospitalization 10/2/2008 64 Female 10/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 11/1/2007 43 Male 10/7/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 11/1/2007 56 Male 10/7/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 12/1/2007 53 Male 10/7/2008 Physician United States
Primary
Concomitant
Neurotoxicity Other Serious 10/28/2008 Physician United Kingdom
Primary
Secondary
Neutropenic Sepsis Death 10/28/2008 Physician United Kingdom
Primary
Secondary
Death Other Serious 10/29/2008 Physician United Kingdom
Primary
Secondary
Pneumonia Fungal Other Serious 11/26/2008 Other Health Professional United States
Primary
Concomitant
Pneumonitis Other Serious 11/26/2008 Other Health Professional United States
Primary
Concomitant
Death Death 67 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 66 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Sinusitis Other Serious 7/1/2008 61 Female 12/3/2008 Consumer United Kingdom
Primary
Concomitant
Sinusitis Other Serious 7/1/2008 61 Female 12/9/2008 Consumer United Kingdom
Primary
Concomitant
Urine Leukocyte Esterase Positive Hospitalization 11/23/2008 Male 209 lb 1/8/2009 United States
Primary
Secondary
Pharyngeal Oedema Hospitalization 12/27/2008 Male 183 lb 12/30/2008 United States
Primary
Secondary
Vomiting Death 24 Male 1/22/2009 Japan
Primary
Concomitant
Sepsis Hospitalization 11/15/2008 Male 192 lb 2/9/2009 United States
Primary
Secondary
Weight Decreased Hospitalization 10/6/2008 Male 192 lb 2/11/2009 United States
Primary
Secondary
Pneumatosis Intestinalis Hospitalization 1/5/2009 1 Female 15 lb 3/30/2009 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/5/2009 1 Female 15 lb 3/27/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2009 1 Female 15 lb 4/13/2009 Physician
Primary
Secondary
Concomitant
Somnolence Other Serious 5 Female 5/4/2009 Other Health Professional Italy
Primary
Secondary
Convulsion Life Threatening 6 Female 5/4/2009 Other Health Professional Italy
Primary
Secondary
Febrile Neutropenia Hospitalization 4/24/2009 Female 180 lb 4/27/2009 United States
Primary
Secondary
Concomitant
Lactobacillus Infection Hospitalization 5/3/2009 1 Male 5/15/2009 Physician
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/2/2009 Male 157 lb 5/19/2009 United States
Primary
Secondary
Embolism Hospitalization 5/14/2009 Female 5/29/2009 Consumer United States
Primary
Concomitant
Embolism Hospitalization 5/14/2009 Female 6/5/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 6/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Sepsis Other Serious 5/6/2009 Female 129 lb 6/19/2009 United States
Primary
Concomitant
Sepsis Other Serious 4/27/2009 17 Female 6/17/2009 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 5/7/2009 Female 6/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 5/6/2009 Female 129 lb 6/26/2009 United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 5/7/2009 Female 7/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/12/2009 Male 163 lb 6/23/2009 United States
Primary
Secondary
Hemiparesis Hospitalization 7/27/2008 13 Male 134 lb 8/5/2009 Pharmacist Belgium
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 8/24/2009 51 Male 153 lb 8/25/2009 Other Health Professional United States
Primary
Secondary
Vasculitis Other Serious 7/27/2008 13 Male 134 lb 9/10/2009 Other Health Professional United States
Primary
Secondary
Respiratory Failure Hospitalization 9/4/2009 Male 11/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombophlebitis Superficial Hospitalization 10/26/2009 Male 149 lb 11/11/2009 United States
Primary
Secondary
Somnolence Other Serious 1/11/2010 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/15/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Mycosis Death 3/1/2007 14 Female 86 lb 4/27/2010 Physician Japan
Primary
Concomitant
Uterine Enlargement Other Serious 32 Female 5/6/2010 Physician Greece
Primary
Secondary
Uterine Enlargement Other Serious 32 Female 5/27/2010 Physician Greece
Primary
Secondary
Uterine Enlargement Other Serious 32 Female 5/28/2010 Physician Greece
Primary
Secondary
Vasculitis Hospitalization 7/27/2008 13 Male 6/6/2010 Belgium
Primary
Secondary
Concomitant
Swelling Face Hospitalization 7/27/2008 13 Male 134 lb 8/19/2010 Pharmacist Belgium
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 1/1/2009 59 Female 132 lb 8/23/2010 Consumer United States
Primary
Secondary
Concomitant
Hemiparesis Other Serious 7/1/2008 13 Male 134 lb 8/26/2010 Other Health Professional Belgium
Primary
Secondary
Klebsiella Sepsis Hospitalization 8/14/2010 59 Male 186 lb 8/27/2010 Physician United States
Primary
Secondary
Urinary Incontinence Other Serious 6/1/2009 59 Female 132 lb 9/1/2010 Physician Germany
Primary
Secondary
Concomitant
Viith Nerve Paralysis Hospitalization 7/27/2008 13 Male 134 lb 9/1/2010 Pharmacist Belgium
Primary
Secondary
Sepsis Other Serious 4/20/2010 1 Male 15 lb 9/3/2010 Physician Japan
Primary
Concomitant
Sepsis Other Serious 4/20/2010 1 Male 15 lb 9/8/2010 Physician United States
Primary
Secondary
Concomitant
Death Hospitalization 9/13/2010 76 Female 148 lb 9/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 9/13/2010 76 Female 148 lb 10/5/2010 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 9/13/2010 76 Female 148 lb 10/28/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/9/2010 59 Male 186 lb 11/23/2010 Physician United States
Primary
Secondary
Klebsiella Sepsis Hospitalization 8/14/2010 59 Male 186 lb 11/24/2010 Physician United States
Primary
Secondary
Staphylococcal Sepsis Other Serious 4/20/2010 1 Male 15 lb 12/10/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
Nerve Injury Hospitalization 50 Male 243 lb 12/23/2010 Pharmacist United States
Primary
Concomitant
Cholestasis Hospitalization 5/1/2008 14 Male 205 lb 1/11/2011 Other Health Professional France
Primary
Secondary
Concomitant
Toothache Other Serious 54 Male 2/10/2011 Other Health Professional Israel
Primary
Concomitant
Haemorrhage Other Serious 3/1/2011 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 3/1/2011 Physician United States
Primary
Secondary
Concomitant
Burning Sensation Hospitalization Male 101 lb 3/3/2011 Other Health Professional Canada
Primary
Concomitant
Angioedema Hospitalization 8 Male 3/1/2011 Pharmacist United States
Primary
Secondary
Concomitant
Stillbirth Hospitalization 28 3/17/2011 Consumer United Kingdom
Primary
Secondary
Nausea Other Serious 28 Female 3/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Lactate Dehydrogenase Increased Other Serious 28 Female 3/18/2011 Other Health Professional United States
Primary
Secondary
Amniotic Fluid Volume Decreased Other Serious 28 3/18/2011 Physician United States
Primary
Secondary

Drug Data