Cymbalta combined with Methadone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Therapeutic Response Unexpected 5/23/2006 51 Female 243 lb 7/19/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 12/13/2003 49 Female 1/24/2007 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea 10/1/2007 Male 11/21/2007 Consumer United States
Primary
Concomitant
Dyspnoea 10/1/2007 Male 12/3/2007 Consumer United States
Primary
Concomitant
Dyspnoea 10/1/2007 Male 12/5/2007 Consumer United States
Primary
Concomitant
Muscle Spasms 10/15/2008 Female 12/31/2008 Consumer
Primary
Concomitant
Renal Failure Acute Other Serious Male 350 lb 2/4/2009 Physician United States
Primary
Concomitant
Tongue Biting Other Serious 1/1/2005 Female 3/24/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 10/10/2007 Male 190 lb 3/27/2009 Consumer
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 10/10/2007 Male 190 lb 3/30/2009 Consumer
Primary
Secondary
Concomitant
Wound Infection Hospitalization 3/1/2009 Female 4/3/2009 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious Male 190 lb 4/14/2009 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious Male 190 lb 4/16/2009 Consumer United States
Primary
Secondary
Concomitant
Migraine 12/10/2008 Male 5/4/2009 Consumer United States
Primary
Concomitant
Unevaluable Event Male 5/4/2009 Physician United States
Primary
Secondary
Concomitant
Tracheostomy Other Serious Female 5/4/2009 Physician United States
Primary
Concomitant
Sleep Disorder Other Serious Male 5/18/2009 Physician United States
Primary
Concomitant
Pruritus 6/1/2008 5/19/2009 Consumer United States
Primary
Concomitant
Drug Toxicity Death 10/1/2007 Male 190 lb 5/19/2009 Consumer United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 10/1/2008 86 Female 115 lb 5/18/2009 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 5/1/2009 19 Male 149 lb 5/22/2009 Pharmacist United States
Primary
Secondary
Concomitant
Tooth Fracture 10/24/2003 Male 5/28/2009 Consumer United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 12/19/2008 Female 126 lb 5/28/2009 United States
Primary
Concomitant
Speech Disorder 5/22/2009 27 Female 200 lb 5/27/2009 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/29/2009 80 Male 6/23/2009 Physician United States
Primary
Concomitant
Migraine Hospitalization 1/1/2006 49 Female 6/22/2009 Consumer United States
Primary
Concomitant
Pulmonary Oedema Other Serious 12/19/2008 Female 126 lb 6/26/2009 United States
Primary
Concomitant
Renal Failure Acute Other Serious Male 350 lb 6/30/2009 Physician United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 6/12/2009 Female 6/30/2009 Physician United States
Primary
Concomitant
Tongue Biting Other Serious 1/1/2005 Female 7/9/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 5/13/2009 Female 7/30/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 12/19/2008 Female 126 lb 8/14/2009 United States
Primary
Concomitant
Headache 5/7/2009 58 Female 7/22/2009 Consumer United States
Primary
Concomitant
Stent Placement Other Serious 3/1/2009 Male 8/17/2009 Pharmacist United States
Primary
Concomitant
Pneumonitis Hospitalization 7/10/2009 56 Female 8/18/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2006 48 Female 201 lb 8/25/2009 United States
Primary
Concomitant
Vitamin B12 Deficiency Other Serious 6/12/2009 Female 8/28/2009 Physician United States
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Other Serious 11/30/2005 43 Female 329 lb 9/23/2009 United States
Primary
Concomitant
Myositis 4/19/2000 60 Female 248 lb 9/23/2009 United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 1/1/2003 46 Female 288 lb 9/23/2009 United States
Primary
Concomitant
Toothache Hospitalization 4/13/2004 42 Male 214 lb 9/23/2009 United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/1/2009 Male 10/5/2009 Other Health Professional United States
Primary
Concomitant
Arrhythmia Other Serious 44 Male 10/27/2009 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/23/2009 10/30/2009 Consumer United States
Primary
Concomitant
Chest Pain Hospitalization 10/10/2009 Female 175 lb 10/30/2009 United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/23/2009 11/6/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 11/17/2009 Physician United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased 8/1/2007 Male 11/30/2009 Physician United States
Primary
Concomitant
Pneumonia Other Serious 10/15/2007 Female 144 lb 11/30/2009 Consumer United States
Primary
Concomitant
Blood Amylase Increased Hospitalization 6/8/2009 38 Male 12/3/2009 Physician Belgium
Primary
Concomitant
Tremor Other Serious 1/1/2007 83 Female 12/1/2009 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 5/19/2008 Female 12/1/2009 Physician United States
Primary
Concomitant
Wound Infection Hospitalization 3/1/2009 Female 12/1/2009 Physician United States
Primary
Concomitant
Tongue Biting Other Serious 1/1/2005 Female 12/1/2009 Consumer United States
Primary
Concomitant
Rash 12/1/2008 80 Female 12/9/2009 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2002 Female 195 lb 12/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 5/17/2009 65 Female 12/29/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 32 Female 149 lb 1/8/2010 United States
Primary
Concomitant
Pain Disability 1/1/2006 Female 1/8/2010 Consumer United States
Primary
Concomitant
Pregnancy Other Serious 8/16/2006 Female 135 lb 1/13/2010 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2002 Female 195 lb 1/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 9/23/2009 1/24/2010 Consumer United States
Primary
Concomitant
Tongue Ulceration Other Serious 10/16/2005 Female 2/19/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 32 Female 149 lb 2/22/2010 United States
Primary
Concomitant
Drug Toxicity Other Serious 35 Female 2/18/2010 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 50 Male 2/19/2010 Physician United States
Primary
Concomitant
Wound Decomposition Other Serious 1/1/2004 Female 2/22/2010 Physician United States
Primary
Concomitant
Tongue Ulceration Other Serious 10/16/2005 Female 2/24/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 32 Female 149 lb 2/25/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 2/25/2010 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased 9/18/2009 61 Female 1/28/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2002 Female 195 lb 3/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 32 Female 149 lb 3/15/2010 United States
Primary
Concomitant
Tongue Ulceration Other Serious 10/16/2005 Female 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2002 Female 195 lb 3/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/5/2002 Female 3/25/2010 Physician United States
Primary
Secondary
Concomitant
Red Blood Cell Sedimentation Rate Increased Hospitalization 1/1/2007 Female 210 lb 3/26/2010 Consumer United States
Primary
Secondary
Concomitant
Hiatus Hernia Hospitalization 3/11/2010 51 Male 3/29/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2002 Female 195 lb 3/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/2004 Female 3/31/2010 Other Health Professional United States
Primary
Concomitant
Tongue Ulceration Other Serious 10/16/2005 57 Female 4/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/5/2002 76 Female 4/1/2010 Physician United States
Primary
Secondary
Concomitant
Tongue Ulceration Other Serious 10/16/2005 57 Female 5/12/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2002 56 Female 195 lb 5/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Off Label Use Other Serious 1/1/2010 29 Female 5/18/2010 Physician United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/25/2002 43 Male 257 lb 6/1/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2002 46 Female 5/29/2010 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 2/18/2010 53 Female 212 lb 5/11/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 12/5/2002 76 Female 6/11/2010 United States
Primary
Secondary
Concomitant
Urinary Retention Other Serious 10/16/2005 57 Female 6/12/2010 United States
Primary
Secondary
Concomitant
Hypoglycaemia Neonatal Hospitalization 8/11/2009 6/18/2010 Physician Switzerland
Primary
Concomitant
Failed Trial Of Labour Other Serious 11/1/2008 40 Female 6/18/2010 Physician Switzerland
Primary
Concomitant
Urinary Tract Infection Hospitalization 4/4/2010 55 Male 180 lb 4/6/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2007 57 Female 157 lb 7/16/2010 Consumer United States
Primary
Secondary
Concomitant
Nightmare 2/9/2009 50 Female 140 lb 7/23/2010 Consumer United States
Primary
Concomitant
Somnolence Female 234 lb 8/3/2010 Consumer United States
Primary
Secondary
Concomitant
Interacting
Vitamin D Abnormal Hospitalization 1/1/2009 66 Female 8/23/2010 Consumer United States
Primary
Concomitant
Suicide Attempt Other Serious 5/1/2010 28 Female 8/27/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 10/16/2005 57 Female 8/30/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2010 58 Male 185 lb 8/31/2010 Consumer United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/2004 69 Female 8/30/2010 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 6/1/2010 50 Female 215 lb 9/1/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 53 Male 280 lb 9/1/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 10/16/2005 57 Female 9/8/2010 United States
Primary
Secondary
Concomitant
Fibromyalgia Other Serious 43 Female 9/10/2010 Consumer United States
Primary
Secondary
Weight Decreased Other Serious 10/16/2005 57 Female 9/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2010 49 Female 174 lb 9/14/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 64 Female 9/16/2010 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2007 49 Male 230 lb 9/20/2010 United States
Primary
Concomitant
Obesity Hospitalization 6/1/2006 51 Male 250 lb 9/20/2010 United States
Primary
Concomitant
Diabetic Coma Other Serious 1/1/2005 50 Male 190 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/14/2005 66 Female 152 lb 9/20/2010 United States
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 1/1/2003 46 Female 288 lb 9/20/2010 United States
Primary
Concomitant
Skin Infection 1/1/2008 43 Male 229 lb 9/28/2010 Consumer United States
Primary
Concomitant
Drug Ineffective 9/1/2010 62 Male 220 lb 10/1/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 8/8/2000 25 Female 10/4/2010 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 10/1/2009 66 Male 10/4/2010 Consumer United States
Primary
Concomitant
Hypertension Other Serious 8/1/2010 50 Female 175 lb 10/6/2010 United States
Primary
Concomitant
Pancreatic Carcinoma Other Serious 7/1/2010 60 Male 10/4/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/16/2005 57 Female 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 8/26/2010 60 Male 264 lb 10/7/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 8/8/2000 25 Female 10/12/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/16/2005 57 Female 10/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Disorder Hospitalization 1/1/2008 35 Male 280 lb 10/18/2010 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/1/2003 29 Male 280 lb 10/19/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 10/16/2005 57 Female 10/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Product Quality Issue 54 Female 10/13/2010 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 12/6/2006 40 Female 10/29/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 10/16/2005 57 Female 11/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 7/1/2010 60 Male 11/1/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious Male 264 lb 11/10/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 8/8/2000 25 Female 11/24/2010 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 10/27/2010 Male 11/17/2010 Physician Germany
Primary
Concomitant
Weight Decreased Other Serious 10/16/2005 57 Female 11/27/2010 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 12/9/2009 66 Male 12/6/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 8/8/2000 25 Female 12/14/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2008 64 Female 2/25/2010 Physician United States
Primary
Secondary
Concomitant
Death Death Female 12/27/2010 Physician Canada
Primary
Concomitant
Rheumatoid Arthritis Other Serious 12/9/2009 66 Male 12/31/2010 Consumer United States
Primary
Concomitant
Paralysis Other Serious 1/1/2008 47 Female 130 lb 1/11/2011 Other Health Professional United States
Primary
Concomitant
Bone Lesion Hospitalization 8/8/2000 25 Female 1/11/2011 United States
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious 8/8/2000 25 Female 1/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Tube Insertion Other Serious Female 1/25/2011 Consumer United States
Primary
Concomitant
Hiatus Hernia Other Serious 10/16/2005 57 Female 1/27/2011 Physician United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 9/15/2010 70 Female 2/10/2011 Consumer United States
Primary
Concomitant
Diverticulum Other Serious 10/16/2005 57 Female 2/11/2011 Lawyer United States
Primary
Secondary
Concomitant
Joint Swelling 27 Female 2/28/2011 Other Health Professional United States
Primary
Concomitant
Cellulitis Other Serious 10/16/2005 57 Female 3/1/2011 Physician United States
Primary
Secondary
Concomitant
Mechanical Ventilation Other Serious 1/17/2010 59 Male 3/3/2011 Consumer United States
Primary
Concomitant
Drug Ineffective For Unapproved Indication Other Serious 10/1/2009 Male 3/10/2011 Consumer United States
Primary
Concomitant

Drug Data