Cyclosporine combined with Voriconazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sepsis Life Threatening 12/6/2005 55 Male 168 lb 12/14/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Tracheostomy Life Threatening 7/10/2005 42 Female 1/23/2006 United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/11/2006 68 Male 2/4/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant Hospitalization 1/26/2006 47 Male 198 lb 1/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tracheostomy Other Serious 65 Male 2/15/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Tracheostomy Hospitalization 40 Male 2/15/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Enterococcal 56 Female 3/9/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 12/1/1999 58 Male 7/10/2006 Other Health Professional Italy
Primary
Secondary
Stem Cell Transplant Hospitalization 9/10/2006 47 Female 266 lb 9/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 8/1/2004 10 Female 10/19/2006 Germany
Primary
Concomitant
Vomiting 2/8/2006 36 Male Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/17/2006 Male 2/14/2007 Physician United States
Primary
Concomitant
Disease Progression Other Serious 45 Female 2/27/2007 Japan
Primary
Concomitant
Thrombocytopenia Other Serious 11/17/2006 Male 3/7/2007 Physician United States
Primary
Concomitant
Systemic Candida Death 45 Female 3/14/2007 Japan
Primary
Concomitant
Pleural Effusion Required Intervention 3/17/2007 28 Male 183 lb 3/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Tubular Disorder Death 7 Female 5/24/2007 Physician Italy
Primary
Secondary
Concomitant
Renal Tubular Disorder Other Serious 7 Female 5/30/2007 Physician Italy
Primary
Secondary
Concomitant
Pseudomembranous Colitis Other Serious 11/17/2006 45 Male 6/25/2007 Japan
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 10/24/2006 41 Male 151 lb 10/24/2006 United States
Primary
Secondary
Concomitant
Renal Tubular Disorder Other Serious 7 Female 8/14/2007 Physician Italy
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4 Female 9/6/2007 Physician Germany
Primary
Secondary
Productive Cough Hospitalization 12/1/2005 Female 105 lb 9/10/2007 United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 28 Male 10/17/2007
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 2/9/2007 57 Female Physician United States
Primary
Concomitant
Venoocclusive Disease Other Serious 9/19/2007 Female 137 lb 11/2/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Convulsion Other Serious 9/3/2007 Male 11/2/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Ureaplasma Infection Other Serious 28 Male 11/5/2007 Switzerland
Primary
Secondary
Concomitant
Venoocclusive Disease Life Threatening 9/19/2007 19 Female 11/19/2007 Consumer United Kingdom
Primary
Secondary
Sleep Disorder Other Serious 6/1/2007 15 Male 139 lb 11/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Dilatation Intrahepatic Duct Acquired Life Threatening 9/19/2007 19 Female 11/21/2007 United Kingdom
Primary
Secondary
Venoocclusive Disease Other Serious 9/19/2007 19 Female 11/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 9/19/2007 19 Female 11/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Disease Other Serious 9/19/2007 19 Female 11/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Dilatation Intrahepatic Duct Acquired Life Threatening 9/19/2007 19 Female 11/26/2007 United Kingdom
Primary
Secondary
Venoocclusive Disease Other Serious 19 Female 11/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Disease Other Serious 9/19/2007 12/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Disease Other Serious 19 Female 11/30/2007 Pharmacist United Kingdom
Primary
Concomitant
Stomatitis Other Serious 6 Male 12/23/2007 Japan
Primary
Concomitant
Pyrexia Hospitalization 2/20/2007 70 Male 12/13/2007 Physician Spain
Primary
Concomitant
Venoocclusive Disease Other Serious 9/19/2007 Female 137 lb 12/26/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 10/5/2007 36 Male 1/16/2008 Netherlands
Primary
Concomitant
Weight Increased Other Serious 9/26/2006 51 Male 172 lb 2/9/2008 Physician France
Primary
Secondary
Concomitant
Wolff-parkinson-white Syndrome Hospitalization 8/6/2007 80 Male 3/6/2008 Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 2/29/2008 Female 178 lb 3/20/2008 United Kingdom
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 2/29/2008 Female 178 lb 3/21/2008 United Kingdom
Primary
Concomitant
Pyrexia Other Serious 10 Male 3/24/2008 Other Health Professional Pakistan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 2/29/2008 Female 178 lb 3/25/2008 United Kingdom
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 36 Female 3/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 17 Male 3/28/2008 Consumer United States
Primary
Secondary
Concomitant
Skin Lesion Excision Other Serious 65 Female 4/11/2008 Other Health Professional Belgium
Primary
Secondary
Venoocclusive Liver Disease Other Serious 2/29/2008 Female 227 lb 4/15/2008 United Kingdom
Primary
Concomitant
Zygomycosis Hospitalization 6/1/2007 76 Male 4/17/2008 Other Health Professional Italy
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 2/29/2008 Female 227 lb 4/23/2008 United Kingdom
Primary
Concomitant
Cardiac Failure Death 3/8/2008 14 Female 4/25/2008 Physician Italy
Primary
Secondary
Concomitant
Vomiting 2/9/2007 57 Female 5/2/2008 Physician United States
Primary
Concomitant
Cardiac Failure Death 3/8/2008 14 Female 5/6/2008 Physician Italy
Primary
Secondary
Concomitant
Weight Increased Other Serious 9/26/2006 Male 172 lb 5/29/2008 Physician France
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 10/1/2007 Female 6/2/2008 Consumer South Africa
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 2/29/2008 Female 227 lb 7/15/2008 United Kingdom
Primary
Concomitant
Diarrhoea Other Serious 6/1/2008 Female 106 lb 7/16/2008 Physician Denmark
Primary
Concomitant
Respiratory Failure Other Serious 31 Male 7/18/2008
Primary
Secondary
Concomitant
Gingival Hyperplasia Hospitalization 7/20/2008 Male 8/7/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 8/15/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Gingival Hyperplasia Hospitalization 7/20/2008 Male 8/21/2008 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Other Serious 6/1/2008 Female 106 lb 9/8/2008 Physician Denmark
Primary
Concomitant
Drug Level Increased Other Serious 7/26/2007 56 Male 168 lb 9/10/2008 Other Health Professional United States
Primary
Concomitant
Neutropenia Other Serious 7 Female 9/25/2008 Other Health Professional Austria
Primary
Secondary
Concomitant
Neutropenia Other Serious 7 Female 10/6/2008 Other Health Professional Austria
Primary
Secondary
Concomitant
Drug Interaction Death 65 Male 10/8/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 10/16/2008 Other Health Professional Brazil
Primary
Secondary
Concomitant
Drug Interaction Other Serious 65 Male 11/4/2008 Italy
Primary
Concomitant
Interacting
Gingival Hyperplasia 7/20/2008 Male 11/24/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2007 54 Male 11/24/2008 Physician Spain
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2007 54 Male 12/2/2008 Physician Spain
Primary
Secondary
Concomitant
Endocarditis Death 53 Male 12/8/2008
Primary
Concomitant
Sinusitis Hospitalization 1/1/2007 60 Male 143 lb 12/16/2008 Physician Spain
Primary
Secondary
Concomitant
Pericardial Effusion Death 53 Male 12/17/2008 France
Primary
Concomitant
Sepsis Other Serious 65 Male 12/18/2008
Primary
Secondary
Sinusitis Hospitalization 1/1/2007 60 Male 143 lb 12/19/2008 Physician Spain
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Hospitalization 8/1/2007 63 Male 12/24/2008 Other Health Professional Spain
Primary
Secondary
Hypotension Other Serious 48 Male 12/18/2008 Japan
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 6/9/2008 60 Male 249 lb 12/22/2008 Physician United States
Primary
Secondary
Concomitant
Cytomegalovirus Viraemia Hospitalization 10/22/2007 47 Female 114 lb 12/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 36 Male 2/2/2009 Other Health Professional Netherlands
Primary
Concomitant
Tachyarrhythmia Other Serious 57 Female 2/12/2009 Other Health Professional Germany
Primary
Concomitant
Ventricular Fibrillation Other Serious 10/5/2007 36 Male 2/13/2009 Netherlands
Primary
Concomitant
Venoocclusive Disease Other Serious 9/19/2007 19 Female 2/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Tachypnoea Other Serious 1/21/2009 Female 154 lb 2/23/2009 Physician United States
Primary
Secondary
Sepsis Other Serious 64 Male 3/13/2009 Other Health Professional Austria
Primary
Concomitant
Nervous System Disorder Other Serious 3/18/2009 Physician Brazil
Primary
Secondary
Nervous System Disorder Other Serious 3/18/2009 Physician Brazil
Primary
Secondary
Respiratory Failure Hospitalization 38 Female 3/23/2009 Other Health Professional Tunisia
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 3/27/2009 Physician Brazil
Primary
Secondary
Nervous System Disorder Other Serious 3/27/2009 Brazil
Primary
Secondary
Lung Disorder Death 1/1/2008 49 Male 3/31/2009 Other Health Professional Japan
Primary
Concomitant
Septic Shock Death 3/4/2009 4/3/2009 Physician Italy
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 38 Female 4/7/2009 Other Health Professional Tunisia
Primary
Secondary
Concomitant
Surgery Other Serious 74 Male 4/8/2009 Other Health Professional United States
Primary
Concomitant
Aplastic Anaemia Hospitalization Male 4/10/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Aplastic Anaemia Hospitalization Male 4/14/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 12/9/2007 4/17/2009 Physician Egypt
Primary
Concomitant
Stomatitis Other Serious 54 Male 4/30/2009 Other Health Professional Spain
Primary
Concomitant
Interacting
Subdural Haematoma Hospitalization 7/11/2007 5/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Function Abnormal Other Serious 12/9/2007 5/4/2009 Physician Egypt
Primary
Concomitant
Rhabdomyolysis Other Serious 54 Male 5/4/2009 Spain
Primary
Concomitant
Interacting
Renal Failure Acute Other Serious 54 Male 5/8/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 54 Male 5/11/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 57 Male 5/8/2009 Physician Spain
Primary
Secondary
Concomitant
Headache Other Serious 3/23/2007 59 5/22/2009 Physician France
Primary
Concomitant
Transplant Rejection Other Serious 2/13/2007 45 5/26/2009 Physician France
Primary
Concomitant
Transplant Rejection Hospitalization 4/9/2009 Male 56 lb 5/27/2009 United States
Primary
Concomitant
Renal Failure Acute Required Intervention 4/1/2009 57 Male 5/13/2009 Other Health Professional United States
Primary
Secondary
Systemic Mycosis Hospitalization 7/1/2006 50 Female 5/29/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/31/2007 37 6/23/2009 Physician Korea, Republic Of
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 6/7/2009 23 6/24/2009 Physician Spain
Primary
Secondary
Concomitant
Septic Shock Death 3/4/2009 64 6/30/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Tachycardia Other Serious 6/27/2009 Male 203 lb 7/6/2009 Physician United States
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 6/3/2009 23 8/4/2009 Physician Spain
Primary
Secondary
Concomitant
Tachycardia Other Serious 6/27/2009 Male 203 lb 8/4/2009 Physician United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 3/5/2009 Male 31 lb 8/7/2009 Other Health Professional United States
Primary
Concomitant
Sepsis Other Serious 3/6/2009 60 Male 128 lb 8/7/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/1/2009 61 Male 8/10/2009 Other Health Professional United States
Primary
Concomitant
Thoracic Cavity Drainage Other Serious 8/1/2006 31 Male 8/21/2009 Physician China
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 8/25/2009 Brazil
Primary
Secondary
Nervous System Disorder Other Serious 8/26/2009 Physician Brazil
Primary
Secondary
Small Intestine Ulcer Other Serious 5/1/2009 61 Male 8/19/2009 Physician United States
Primary
Concomitant
Tachycardia Other Serious 6/27/2009 Male 203 lb 9/2/2009 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 6/3/2009 23 9/8/2009 Physician Spain
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Hospitalization 4/22/2009 Male 9/11/2009 Physician United States
Primary
Concomitant
Septic Shock Life Threatening 8/31/2007 37 9/25/2009 Physician Korea, Republic Of
Primary
Concomitant
Sepsis Other Serious 5/1/2009 61 Male 9/14/2009 Physician United States
Primary
Concomitant
Venoocclusive Disease Death 9 Male 10/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Other Serious 6/27/2009 Male 203 lb 10/13/2009 Physician United States
Primary
Secondary
Concomitant
Death Death 3/2/2006 27 10/28/2009 Physician Korea, Republic Of
Primary
Concomitant
Graft Versus Host Disease Death 2/28/2006 27 Male 121 lb 11/9/2009 Physician Korea, Republic Of
Primary
Concomitant
Transplant Failure Other Serious 14 Female 11/16/2009 Consumer United Kingdom
Primary
Secondary
Systemic Mycosis Hospitalization 7/1/2006 50 Female 11/24/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Partial Seizures Life Threatening 11/22/2009 35 Male 168 lb 11/27/2009 Italy
Primary
Secondary
Concomitant
Bronchopulmonary Aspergillosis Other Serious 64 Male 12/7/2009 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 64 Male 12/7/2009 Physician Germany
Primary
Secondary
Concomitant
Multi-organ Failure Death 10/1/2009 52 Male 12/22/2009 Physician Japan
Primary
Concomitant
Bronchopulmonary Aspergillosis Other Serious 64 Male 1/15/2010
Primary
Secondary
Concomitant
Visual Acuity Reduced Death 2/28/2006 27 Male 121 lb 1/25/2010 Physician Korea, Republic Of
Primary
Concomitant
Septic Embolus Other Serious 24 Female 1/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Retrograde Portal Vein Flow Disability 12/20/2009 Female 2/8/2010 Physician Germany
Primary
Secondary
Concomitant
Organ Failure Death 6/1/2009 63 Female 119 lb 2/12/2010 Physician Belgium
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 11 Male 3/1/2010 Other Health Professional United States
Primary
Secondary
Squamous Cell Carcinoma Other Serious 9 Male 3/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Telangiectasia Other Serious 43 Male 3/1/2010 Other Health Professional United States
Primary
Secondary

Drug Data