Cyclosporine combined with Thiotepa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Neurotoxicity Other Serious 26 Female 3/4/2006 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 38 Female 3/4/2006 Physician United States
Primary
Concomitant
Renal Impairment Other Serious 8/15/2005 21 Male 88 lb 3/10/2006 Japan
Primary
Concomitant
Venoocclusive Disease Other Serious 22 Male 3/14/2006 Japan
Primary
Secondary
Transaminases Increased Other Serious 9 Male 41 lb 5/8/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Vomiting Death 2/25/2007 13 Female 8/1/2007 Japan
Primary
Concomitant
Haemolytic Uraemic Syndrome Other Serious 6 3/11/2008 Consumer Japan
Primary
Concomitant
Haemolytic Uraemic Syndrome Other Serious 6 3/24/2008 Physician Japan
Primary
Concomitant
Urinary Tract Infection Other Serious Female 3/28/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulmonary Toxicity Other Serious Female 3/28/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Other Serious Female 3/28/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Sepsis Other Serious Female 3/28/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 5/22/2008 Japan
Primary
Secondary
Concomitant
Oral Herpes Other Serious 16 Female 6/18/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 48 Male 6/20/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Pulmonary Sepsis Life Threatening 6/1/2004 51 Male 7/7/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/30/2008 45 Male 163 lb 7/16/2008 Physician Spain
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/30/2008 45 Male 163 lb 7/22/2008 Physician Spain
Primary
Secondary
Concomitant
Renal Failure Other Serious 14 Male 8/22/2008 Other Health Professional Italy
Primary
Secondary
Rash Hospitalization 6/30/2008 45 Male 163 lb 9/17/2008 Physician Spain
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 11/5/2008 63 Male 11/20/2008 Other Health Professional Spain
Primary
Concomitant
Staphylococcal Sepsis Other Serious 32 Male 12/1/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 11/5/2008 63 Male 12/4/2008 Other Health Professional Spain
Primary
Concomitant
Basal Cell Carcinoma Other Serious 1/1/2004 4 Female 1/7/2009 Italy
Primary
Secondary
Scleroderma Other Serious 1/1/2004 Female 1/19/2009 Other Health Professional Italy
Primary
Secondary
Hypothyroidism Other Serious 1/1/2004 Female 1/19/2009 Other Health Professional Italy
Primary
Secondary
Staphylococcal Infection Other Serious 11/5/2008 63 Male 1/26/2009 Other Health Professional Spain
Primary
Concomitant
Pneumonia Cytomegaloviral Death 3/5/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 1/27/2009 59 Male 2/25/2009 Other Health Professional Spain
Primary
Concomitant
Zygomycosis Other Serious 46 Male 3/17/2009 Other Health Professional Italy
Primary
Concomitant
Somnolence Hospitalization 1/30/2009 Male 166 lb 3/20/2009 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 2/1/2009 59 Male 3/26/2009 Other Health Professional Spain
Primary
Concomitant
Mucosal Inflammation Other Serious 16 Male 8/21/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Rash Other Serious 41 Female 10/23/2009 Other Health Professional Italy
Primary
Concomitant
Somnolence Life Threatening 9/16/2009 Male 120 lb 11/2/2009 Physician Netherlands
Primary
Concomitant
Somnolence Life Threatening 9/15/2009 Male 120 lb 11/11/2009 Physician Netherlands
Primary
Concomitant
Respiratory Failure Death 12/8/2009 29 Female 1/13/2010 Physician Italy
Primary
Secondary
Sepsis Death 17 Male 2/23/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Death 13 Female 2/23/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Zygomycosis Other Serious 1/1/2006 Male 2/12/2010 Physician Italy
Primary
Concomitant
Intracranial Hypotension Hospitalization 2/23/2010 51 Male 3/17/2010 Physician Italy
Primary
Secondary
Concomitant
Intracranial Hypotension Hospitalization 2/23/2010 51 Male 3/19/2010 Physician Italy
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Death 3/25/2010 Italy
Primary
Secondary
Concomitant
Vitritis Other Serious 0 Female 3/26/2010 Austria
Primary
Secondary
Concomitant
Wernicke's Encephalopathy Disability 5/9/2008 4/13/2010 Physician United States
Primary
Secondary
Wernicke's Encephalopathy Disability 5/9/2008 4/20/2010 Physician United States
Primary
Secondary
Intracranial Hypotension Hospitalization 2/23/2010 51 Male 5/12/2010 Physician United States
Primary
Secondary
Concomitant
Mycobacterial Infection Other Serious 10 Female 6/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 2 Female 6/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 13 Female 6/11/2010 Physician United States
Primary
Secondary
Concomitant
Relapsing-remitting Multiple Sclerosis Other Serious 38 Female 6/21/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 10 Female 8/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 13 Female 8/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 14 Male 8/27/2010 Italy
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 8/30/2010 Physician Italy
Primary
Concomitant
Unevaluable Event Other Serious Male 8/30/2010 Physician Italy
Primary
Concomitant
Stomatitis Other Serious 1 Male 9/21/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 1 Male 9/21/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Death 9/22/2010 Physician Spain
Primary
Concomitant
Malignant Neoplasm Progression Death 9/22/2010 Physician Spain
Primary
Concomitant
Venoocclusive Disease Death 9/28/2010 Germany
Primary
Secondary
Skin Toxicity Other Serious 0 Female 9/29/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 9 Female 9/30/2010 Physician Italy
Primary
Concomitant
Somnolence Hospitalization 6/16/2010 61 Male 10/21/2010 Physician Germany
Primary
Secondary
Concomitant
Vulvovaginitis Other Serious 10/20/2010 Physician Italy
Primary
Concomitant
Sepsis Other Serious 14 Male 10/20/2010 Physician Italy
Primary
Concomitant
Ureteric Stenosis Death 10/20/2010 Physician Italy
Primary
Concomitant
Venoocclusive Disease Death 11/8/2010 Other Health Professional Germany
Primary
Secondary
Enterococcal Sepsis Death 11 Female 12/17/2010 Physician Italy
Primary
Secondary
Concomitant
Pancytopenia Death 11 Female 12/21/2010 United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 3/1/2007 22 Female 99 lb 12/29/2010 Physician Japan
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 23 Female 12/19/2010 Physician Italy
Primary
Concomitant
Staphylococcal Sepsis Death 3/1/2007 22 Female 99 lb 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Death Other Serious 4/26/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 3/1/2007 22 Female 99 lb 4/28/2011 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/9/2009 19 Female 4/29/2011 Physician United States
Primary
Concomitant
Diabetes Mellitus Other Serious 18 Female 5/27/2011 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Death 18 Female 5/27/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Other Serious 47 Female 6/14/2011 Other Health Professional Spain
Primary
Secondary
Concomitant
Cytomegalovirus Infection Life Threatening Female 6/15/2011 Pharmacist United Kingdom
Primary
Concomitant
T-lymphocyte Count Decreased Other Serious 39 Female 6/16/2011 Other Health Professional Spain
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 8 Female 6/21/2011 Pharmacist United Kingdom
Primary
Concomitant
Venoocclusive Disease Hospitalization 6/21/2011 Pharmacist United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization Male 6/22/2011 Pharmacist United Kingdom
Primary
Concomitant
Neoplasm Malignant Death 5 6/25/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Acute Graft Versus Host Disease Death 3 6/25/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
T-lymphocyte Count Decreased Other Serious 47 Female 7/1/2011 Other Health Professional Spain
Primary
Secondary
Concomitant
Anaemia Haemolytic Autoimmune Other Serious 39 Female 7/1/2011 Other Health Professional Spain
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 18 Female 7/1/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 1/19/2011 3 Male 35 lb 7/7/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Posterior Reversible Encephalopathy Syndrome Death 12/7/2010 6 Female 40 lb 7/7/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Bacterial Sepsis Hospitalization 5/16/2011 8 Female 55 lb 7/12/2011 Pharmacist United Kingdom
Primary
Concomitant
Venoocclusive Disease Hospitalization 1/19/2011 3 Male 35 lb 7/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Csf Protein Increased Other Serious 48 Male 7/5/2011 Other Health Professional Spain
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 7/19/2011 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 12/7/2010 7 Female 40 lb 7/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Abnormal Other Serious 38 Male 7/20/2011 Other Health Professional China
Primary
Secondary
Concomitant
Aspergillosis Death 67 Male 8/1/2011 Other Health Professional Germany
Primary
Secondary
Transient Ischaemic Attack Other Serious 14 Female 8/12/2011 Other Health Professional Canada
Primary
Concomitant
Multi-organ Failure Death 3/1/2007 22 Female 99 lb 8/18/2011 Physician Japan
Primary
Secondary
Concomitant
Haemolysis Other Serious 29 Female 9/21/2011 Other Health Professional Germany
Primary
Concomitant
Lung Consolidation Other Serious 1/19/2011 3 Male 35 lb 9/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 9/20/2011 2 Male 33 lb 9/28/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Life Threatening 5/16/2011 8 Female 49 lb 9/29/2011 Pharmacist United Kingdom
Primary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 33 lb 9/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cytomegalovirus Infection Life Threatening 1/19/2011 3 Male 35 lb 10/3/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Deep Vein Thrombosis Death 12/7/2010 6 Female 40 lb 10/4/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 35 lb 10/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 1/1/2011 4 Male 37 lb 10/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Posterior Reversible Encephalopathy Syndrome Death 16 Female 10/17/2011 Other Health Professional Italy
Primary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 33 lb 10/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 9/19/2011 2 Male 33 lb 10/19/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Haematemesis Other Serious 4 Male 38 lb 10/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2011 8 Female 49 lb 10/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 35 lb 10/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Disorder Other Serious 1/1/2011 8 Female 49 lb 12/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 35 lb 1/6/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 35 lb 1/3/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 8 Male 1/24/2012 Other Health Professional Italy
Primary
Concomitant
Pneumonia Cytomegaloviral Death Male 2/2/2012 Physician United Kingdom
Primary
Secondary
Transplant Failure Death 29 Female 2/24/2012 Physician Germany
Primary
Secondary
Concomitant
Haematemesis Other Serious 4 Male 2/2/2012 Other Health Professional United Kingdom
Primary
Secondary
Lymphatic Disorder Other Serious 34 Female 4/12/2012 Spain
Primary
Concomitant
Lymphatic Disorder Other Serious 24 Female 4/12/2012 Other Health Professional Spain
Primary
Concomitant
Neutropenia Death 9/19/2011 2 Male 33 lb 4/23/2012 Physician Germany
Primary
Secondary
Concomitant
Transplant Failure Other Serious 29 Female 5/2/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Recurrent Death 15 Male 5/16/2012 Other Health Professional Uruguay
Primary
Concomitant
Acute Graft Versus Host Disease Death 1 Male 5/16/2012 Other Health Professional Uruguay
Primary
Concomitant
Pneumonia Cytomegaloviral Death 9 Male 5/16/2012 Other Health Professional Uruguay
Primary
Concomitant
Acute Lymphocytic Leukaemia Recurrent Death 5 Female 5/16/2012 Other Health Professional Uruguay
Primary
Concomitant
Chronic Graft Versus Host Disease Other Serious 17 Female 5/16/2012 Other Health Professional Uruguay
Primary
Concomitant
Acute Lymphocytic Leukaemia Recurrent Other Serious 5 Male 5/16/2012 Other Health Professional Uruguay
Primary
Concomitant
Transplant Rejection Death 5 Male 5/16/2012 Other Health Professional Uruguay
Primary
Concomitant
Acute Graft Versus Host Disease Death 1 Male 5/16/2012 Other Health Professional Uruguay
Primary
Concomitant
Transplant Rejection Death 5 Male 5/16/2012 Other Health Professional Uruguay
Primary
Concomitant
Sepsis Other Serious 5/21/2012 Other Health Professional Germany
Primary
Concomitant
Stupor Other Serious 5/21/2012 Other Health Professional Germany
Primary
Concomitant
Sepsis Other Serious 5/21/2012 Other Health Professional Germany
Primary
Concomitant
Stupor Death 5/21/2012 Other Health Professional Germany
Primary
Concomitant
Graft Versus Host Disease In Intestine Death 5/24/2012 Other Health Professional Germany
Primary
Concomitant
Graft Versus Host Disease In Intestine Death Male 5/24/2012 Other Health Professional Germany
Primary
Concomitant
Neurological Symptom Other Serious 5/24/2012 Other Health Professional Germany
Primary
Concomitant
Disease Progression Death Male 5/24/2012 Other Health Professional Germany
Primary
Concomitant
Graft Versus Host Disease In Intestine Death 5/24/2012 Other Health Professional Germany
Primary
Concomitant
Decerebration Death 18 Male 6/13/2012 Other Health Professional Italy
Primary
Concomitant
Graft Versus Host Disease In Skin Other Serious 18 Male 6/13/2012 Other Health Professional Italy
Primary
Concomitant
Status Epilepticus Death 16 Female 7/11/2012 Other Health Professional Italy
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 43 Female 7/19/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 43 Female 7/19/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Death 43 Female 8/3/2012 Other Health Professional Japan
Primary
Secondary
Concomitant

Drug Data