Cyclosporine combined with Phenytoin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Refusal Of Treatment By Patient Other Serious 19 Female 110 lb 1/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 3/28/2003 31 Male 4/27/2006 Japan
Primary
Concomitant
Therapy Non-responder Other Serious 7/30/2004 31 Male 6/16/2006 Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 11/10/2006 45 Female 4/4/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 5/1/2005 Female 4/17/2007 Other Health Professional United States
Primary
Concomitant
Stomatitis 2/5/2007 47 Male 6/6/2007 Japan
Primary
Concomitant
Staphylococcal Sepsis Death 4/29/2007 21 Female 6/14/2007 Japan
Primary
Concomitant
Transplant Failure 2/5/2007 47 Male 7/13/2007 Japan
Primary
Concomitant
Vomiting Death 5/5/2007 21 Female 9/4/2007 Other Health Professional Japan
Primary
Concomitant
Visual Field Defect Other Serious 11/1/2007
Primary
Secondary
Venoocclusive Liver Disease Life Threatening 11/1/2006 53 Male 12/19/2007 Other Health Professional Japan
Primary
Concomitant
Infection Death 2/19/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Adenocarcinoma Death 2/21/2008 Canada
Primary
Secondary
Concomitant
Sepsis Other Serious 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Sepsis Other Serious 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Sepsis Other Serious 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Infection Other Serious 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Infection Other Serious 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Infection Other Serious 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Infection Death 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Infection Death 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Death 2/22/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Infection Death 2/22/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Arrhythmia Death 2/22/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Death 2/22/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Encephalopathy Death 2/22/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 2/22/2008 Canada
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 2/22/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Sacroiliitis Other Serious 11/9/2007 42 Male 3/14/2008 Physician Finland
Primary
Concomitant
Ventricular Extrasystoles Life Threatening 10/7/2007 57 Male 4/30/2008 Japan
Primary
Concomitant
Vomiting Life Threatening 5/28/2007 25 Male 4/30/2008 Japan
Primary
Concomitant
Renal Failure Acute Other Serious 5/29/2008 Iceland
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/2/2008 Iceland
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 9 Female 6/13/2008 Germany
Primary
Secondary
Venoocclusive Liver Disease Hospitalization 7/1/2007 50 Male 6/19/2008 Japan
Primary
Concomitant
Infection Death 6/26/2008 Spain
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 9 Female 6/25/2008 Other Health Professional Germany
Primary
Concomitant
Vomiting Life Threatening 9/24/2007 58 Male 6/27/2008 Other Health Professional Japan
Primary
Concomitant
Vomiting Hospitalization 3/22/2007 64 Male 6/30/2008 Physician Japan
Primary
Concomitant
Enterobacter Sepsis Hospitalization 8/21/2007 29 Male 7/8/2008 Japan
Primary
Concomitant
Pneumonia Hospitalization 7/28/2007 47 Male 7/8/2008 Japan
Primary
Concomitant
Stem Cell Transplant Hospitalization 5/12/2008 60 Female 200 lb 7/14/2008 Physician United States
Primary
Secondary
Concomitant
Grand Mal Convulsion Life Threatening 2/17/2007 5 Female 7/16/2008 Japan
Primary
Concomitant
Vomiting Death 8/2/2007 28 Female 7/17/2008 Other Health Professional Japan
Primary
Concomitant
Stomatitis Hospitalization 4/15/2008 16 Male 7/17/2008 Other Health Professional Japan
Primary
Concomitant
Transplant Rejection 12/27/2006 13 Female 7/18/2008 Japan
Primary
Concomitant
Stomatitis 2/21/2008 6 Female 7/18/2008 Japan
Primary
Concomitant
Vomiting Hospitalization 5/20/2007 59 Female 8/14/2008 Japan
Primary
Concomitant
Vomiting Death 8/20/2007 28 Female 8/29/2008 Japan
Primary
Concomitant
Vomiting Hospitalization 3/6/2008 16 Male 9/3/2008 Japan
Primary
Concomitant
Transplant Failure Life Threatening 5/23/2007 55 Female 9/8/2008 Japan
Primary
Concomitant
Vomiting Life Threatening 7/9/2007 12 Female 9/8/2008 Japan
Primary
Concomitant
Stomatitis Life Threatening 12/27/2006 13 Female 9/23/2008 Japan
Primary
Concomitant
Sepsis Other Serious 2/12/2008 Canada
Primary
Secondary
Concomitant
Vomiting Death 8/30/2006 46 Male 10/13/2008 Japan
Primary
Concomitant
Liver Function Test Abnormal Death 8/30/2006 46 Male 10/20/2008 Japan
Primary
Concomitant
Transplant Failure Hospitalization 9 Female 11/21/2008 Germany
Primary
Concomitant
Vomiting Life Threatening 9/24/2007 58 Male 12/9/2008 Japan
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 6/9/2008 60 Male 249 lb 12/22/2008 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 6/9/2008 60 Male 249 lb 1/13/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 9/15/2007 58 Male 1/27/2009 Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 4/28/2007 17 Female 2/26/2009 Japan
Primary
Concomitant
Pneumonia Life Threatening 10/8/2008 65 Male 132 lb 8/6/2009 Physician Japan
Primary
Secondary
Concomitant
Nausea Other Serious 10/29/2008 58 Female 106 lb 9/8/2009 Physician Japan
Primary
Secondary
Concomitant
Nausea Other Serious 10/29/2008 58 Female 106 lb 9/15/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 10/9/2009 Iceland
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 1/11/2010 Consumer Spain
Primary
Concomitant
Sepsis Other Serious 15 Male 5/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 10 Female 6/1/2010 Other Health Professional United States
Primary
Concomitant
Vitiligo Other Serious 10 Male 6/1/2010 Other Health Professional United States
Primary
Concomitant
Ovarian Failure Other Serious 16 Female 6/1/2010 Other Health Professional United States
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 7 Male 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ovarian Failure Other Serious 16 Female 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 9 Male 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 2 Female 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 14 Male 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 9 Female 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 10 Female 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 4 Male 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 9 Female 7/27/2010 Other Health Professional United States
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 11 Female 7/27/2010 Other Health Professional United States
Primary
Concomitant
Leukoencephalopathy Other Serious 7 Male 7/27/2010 Other Health Professional United States
Primary
Concomitant
Restrictive Pulmonary Disease Other Serious 9 Male 8/3/2010 Physician United States
Primary
Concomitant
Restrictive Pulmonary Disease Other Serious 11 Male 8/3/2010 Physician United States
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 7 Male 8/3/2010 Physician United States
Primary
Concomitant
Stem Cell Transplant Other Serious 4 Male 8/3/2010 Physician United States
Primary
Concomitant
Herpes Zoster Other Serious 10 Male 8/3/2010 Physician United States
Primary
Concomitant
Ovarian Failure Other Serious 10 Female 8/3/2010 Physician United States
Primary
Concomitant
Sepsis Other Serious 14 Male 8/3/2010 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 9 Female 8/3/2010 Physician United States
Primary
Concomitant
Ovarian Failure Other Serious 16 Female 8/3/2010 Physician United States
Primary
Concomitant
Anaemia Haemolytic Autoimmune Other Serious 10 Male 8/2/2010 Physician United States
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 2 Female 8/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 10 Male 8/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Premature Menopause Other Serious 16 Female 8/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 11 Female 8/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 7 Male 8/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 9 Female 8/4/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 4 Male 8/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 15 Male 8/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/1/2000 Female 9/10/2010 Physician Sweden
Primary
Concomitant
Interacting
Vertigo Hospitalization 1/1/2000 Female 10/13/2010 Physician Sweden
Primary
Concomitant
Interacting
Stomatitis Other Serious 8 Female 12/6/2010 Physician Thailand
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 8 Male 12/6/2010 Physician Thailand
Primary
Concomitant
Vomiting Other Serious 6 Male 12/6/2010 Physician Thailand
Primary
Concomitant
Enteritis Other Serious 5 Male 12/6/2010 Physician Thailand
Primary
Concomitant
Hypertension Hospitalization 10/22/2010 47 Male 2/9/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Dehydration Other Serious 10/1/2010 47 Male 2/11/2011 Other Health Professional Canada
Primary
Concomitant
Hyperbilirubinaemia Hospitalization 10/4/2010 47 Male 295 lb 3/24/2011 Other Health Professional Canada
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 4/15/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Hyperbilirubinaemia Hospitalization 10/4/2010 47 Male 295 lb 4/21/2011 Other Health Professional Canada
Primary
Concomitant
Mucosal Inflammation Hospitalization 10/4/2010 47 Male 295 lb 4/22/2011 Physician Canada
Primary
Secondary
Concomitant
Bk Virus Infection Other Serious 10/4/2010 47 Male 295 lb 5/25/2011 Other Health Professional Canada
Primary
Concomitant
Graft Versus Host Disease Other Serious 2 Female 4/1/2011 Physician United States
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 10/4/2010 47 Male 295 lb 6/8/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Bk Virus Infection Hospitalization 10/4/2010 47 Male 295 lb 6/27/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
C-reactive Protein Increased Death 6/30/2002 16 Female 73 lb 6/28/2011 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/4/2010 47 Male 295 lb 6/29/2011 Other Health Professional Canada
Primary
Concomitant
Respiratory Failure Death 10/4/2010 47 Male 295 lb 7/1/2011 Other Health Professional Canada
Primary
Concomitant
Dehydration Hospitalization 10/4/2010 47 Male 295 lb 7/5/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Dermatitis Other Serious 9 Female 6/29/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 10/4/2010 47 Male 295 lb 7/26/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Cytomegalovirus Test Positive Other Serious 8/31/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 1/23/2004 53 Male 9/5/2011 Physician Switzerland
Primary
Concomitant
Leukoencephalopathy Other Serious 9 Male 9/23/2011 Other Health Professional Brazil
Primary
Secondary
Concomitant
Lung Consolidation Other Serious 1/19/2011 3 Male 35 lb 9/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 33 lb 9/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Methylobacterium Infection Other Serious 5/22/2011 8 Female 49 lb 9/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Periorbital Oedema Life Threatening 1/27/2011 6 Female 40 lb 10/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cytomegalovirus Infection Life Threatening 1/19/2011 3 Male 35 lb 10/3/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Deep Vein Thrombosis Death 12/7/2010 6 Female 40 lb 10/4/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2011 8 Female 49 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 35 lb 10/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 1/1/2011 4 Male 37 lb 10/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Methylobacterium Infection Other Serious 8 Female 49 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 6 Female 40 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 10/13/2011 Other Health Professional China
Primary
Secondary
Concomitant
Venoocclusive Disease Death 10/13/2011 Other Health Professional China
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Death 10/13/2011 Other Health Professional China
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 33 lb 10/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haematemesis Other Serious 4 Male 38 lb 10/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2011 8 Female 49 lb 10/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 35 lb 10/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Disorder Other Serious 1/1/2011 8 Female 49 lb 12/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 35 lb 1/6/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 35 lb 1/3/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious Male 2/7/2012 Other Health Professional India
Primary
Concomitant

Drug Data