Cyclosporine combined with Mycophenolate Mefetil

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hepatotoxicity Other Serious 2 Male 7/26/2006 China
Primary
Secondary
Concomitant
Graft Loss Other Serious 16 Female 2/18/2011 Physician Thailand
Primary
Secondary
Sudden Cardiac Death Death 1/28/2011 55 Female 122 lb 2/18/2011 Physician Germany
Primary
Concomitant
Hyperbilirubinaemia Hospitalization 10/4/2010 47 Male 295 lb 3/24/2011 Other Health Professional Canada
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 1/1/2006 3/28/2011 Physician France
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/20/2011 60 Female 134 lb 4/5/2011 Physician United Kingdom
Primary
Secondary
Hyperbilirubinaemia Hospitalization 10/4/2010 47 Male 295 lb 4/21/2011 Other Health Professional Canada
Primary
Concomitant
Mucosal Inflammation Hospitalization 10/4/2010 47 Male 295 lb 4/22/2011 Physician Canada
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Recurrent Death 1/20/2011 60 Female 134 lb 4/22/2011 Consumer United Kingdom
Primary
Secondary
Mucosal Inflammation Other Serious 17 Female 4/26/2011 Physician Germany
Primary
Secondary
Concomitant
Bacterial Infection Other Serious 10 Male 4/26/2011 Physician Germany
Primary
Secondary
Concomitant
Renal Impairment Death 10/11/2007 Male 14 lb 5/9/2011 Pharmacist United States
Primary
Secondary
Concomitant
Renal Impairment Death 10/11/2007 Male 14 lb 5/11/2011 Pharmacist United States
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 24 Male 5/19/2011 Physician China
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 44 Female 5/19/2011 Physician China
Primary
Secondary
Concomitant
Bk Virus Infection Other Serious 10/4/2010 47 Male 295 lb 5/25/2011 Other Health Professional Canada
Primary
Concomitant
Blood Creatinine Increased Hospitalization 7/28/2007 21 Male 5/31/2011 Other Health Professional Mexico
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 10/12/2010 44 Female 5/31/2011 Other Health Professional United States
Primary
Secondary
Acute Graft Versus Host Disease Hospitalization 4/22/2011 61 Male 5/31/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 72 Male 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Chronic Graft Versus Host Disease Other Serious 57 Male 6/1/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 12 Female 6/1/2011 Other Health Professional Japan
Primary
Concomitant
Convulsion Other Serious Male 5/23/2011 Physician France
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 37 Male 6/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 39 Female 6/3/2011 Physician France
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Death 14 Female 6/6/2011 Other Health Professional Korea, Republic Of
Primary
Secondary
Diabetes Mellitus Death 6/7/2011 Other Health Professional Japan
Primary
Secondary
Venoocclusive Disease Other Serious 6/7/2011 Other Health Professional France
Primary
Secondary
Cystitis Haemorrhagic Other Serious 10/4/2010 47 Male 295 lb 6/8/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Delirium Other Serious 10 Male 6/8/2011 Other Health Professional Thailand
Primary
Concomitant
Pneumonia Aspiration Death 39 Female 6/8/2011 Other Health Professional France
Primary
Secondary
Concomitant
Lymphocele Other Serious 9/10/2003 47 Male 5/31/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Nasopharyngitis Hospitalization 9/3/2004 62 Male 6/6/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Leukopenia Other Serious 11/29/2005 47 Female 5/31/2011 Other Health Professional Mexico
Primary
Concomitant
Acute Respiratory Failure Hospitalization 2/2/2008 64 Male 6/6/2011 Physician United States
Primary
Concomitant
Death Death 2/1/2004 60 Female 5/31/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Vaginal Haemorrhage Hospitalization 10/12/2010 44 Female 6/9/2011 Physician United States
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 39 Female 6/10/2011 Physician France
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 39 Female 6/13/2011 Other Health Professional France
Primary
Secondary
Concomitant
Multi-organ Failure Death 40 6/14/2011 Other Health Professional Germany
Primary
Secondary
Graft Versus Host Disease Death 55 6/15/2011 Other Health Professional Germany
Primary
Secondary
Sepsis Other Serious 50 6/15/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 60 6/15/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 25 6/15/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Multi-organ Failure Death 40 6/15/2011 Other Health Professional Germany
Primary
Secondary
Infection Life Threatening 4/27/2011 42 Female 188 lb 6/16/2011 Consumer United States
Primary
Secondary
Concomitant
Disease Progression Other Serious 57 Male 6/17/2011 Other Health Professional France
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Hospitalization 4/22/2011 61 Male 6/17/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 39 Female 6/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatic Fibrosis Other Serious 57 Male 6/17/2011 Other Health Professional France
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 24 Male 6/21/2011 Physician China
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 30 Male 6/21/2011 Physician China
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 20 Male 6/21/2011 Physician China
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 24 Male 6/21/2011 Physician China
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 55 Male 6/21/2011 Physician China
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 44 Female 6/21/2011 Physician China
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 31 Female 6/21/2011 Physician China
Primary
Secondary
Concomitant
Perineal Ulceration Other Serious 6/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bronchiectasis Other Serious 39 Female 6/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bronchiectasis Other Serious 61 Male 6/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Bronchiectasis Other Serious 70 Male 6/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Bronchiectasis Other Serious 52 Male 6/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Bronchiectasis Other Serious 61 Female 6/24/2011 Other Health Professional Ukraine
Primary
Secondary
Concomitant
Bronchiectasis Other Serious 39 Female 6/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypogammaglobulinaemia Other Serious 70 Male 6/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Hypogammaglobulinaemia Other Serious 61 Female 6/24/2011 Other Health Professional Ukraine
Primary
Secondary
Concomitant
Hypogammaglobulinaemia Other Serious 61 Male 6/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Hypogammaglobulinaemia Other Serious 52 Male 6/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Pleural Effusion Other Serious 6/27/2011 Other Health Professional Austria
Primary
Secondary
Bk Virus Infection Hospitalization 10/4/2010 47 Male 295 lb 6/27/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 6/29/2011 Other Health Professional China
Primary
Secondary
Sepsis Hospitalization 10/4/2010 47 Male 295 lb 6/29/2011 Other Health Professional Canada
Primary
Concomitant
Fungal Infection Death 42 Male 6/29/2011 Physician China
Primary
Secondary
Concomitant
Disease Recurrence Other Serious 36 Female 6/15/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Headache Other Serious 14 Female 6/30/2011 Other Health Professional France
Primary
Concomitant
Respiratory Failure Death 10/4/2010 47 Male 295 lb 7/1/2011 Other Health Professional Canada
Primary
Concomitant
Dehydration Hospitalization 10/4/2010 47 Male 295 lb 7/5/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Bronchiectasis Other Serious 70 Male 7/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Hypogammaglobulinaemia Other Serious 52 Male 7/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Bronchiectasis Other Serious 39 Female 7/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bronchiectasis Other Serious 61 Male 7/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Bronchiectasis Other Serious 70 Male 7/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Bronchiectasis Other Serious 39 Female 7/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bronchiectasis Other Serious 61 Male 7/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Hypogammaglobulinaemia Other Serious 52 Male 7/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Renal Lymphocele Hospitalization 1/18/2011 75 Male 165 lb 7/6/2011 Physician France
Primary
Secondary
Concomitant
Hepatic Lesion Other Serious 1/1/2011 10 Male 7/8/2011 Other Health Professional Turkey
Primary
Secondary
Bronchiectasis Other Serious 39 Female 7/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Hypogammaglobulinaemia Other Serious 39 Female 7/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Hypogammaglobulinaemia Other Serious 70 Male 7/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Bronchiectasis Other Serious 70 Male 7/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Hypogammaglobulinaemia Other Serious 39 Female 7/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Odynophagia Other Serious 1/1/2010 23 Male 7/12/2011 Physician United States
Primary
Secondary
Blood Creatinine Increased Hospitalization 1/18/2011 75 Male 161 lb 7/12/2011 Physician France
Primary
Secondary
Concomitant
Haemoglobin Decreased Life Threatening 1/4/2008 27 Male 128 lb 7/12/2011 Physician Germany
Primary
Secondary
Bronchiectasis Other Serious 39 Female 7/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Kaposi's Sarcoma Hospitalization 1/19/2007 33 Male 7/12/2011 Other Health Professional Poland
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 7/12/2011 Other Health Professional Poland
Primary
Secondary
Bronchiectasis Other Serious 2/25/2010 61 Female 7/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Bronchiectasis Other Serious 2/25/2010 52 Male 7/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Bronchiectasis Other Serious 2/25/2010 39 Female 7/12/2011 United Kingdom
Primary
Secondary
Concomitant
Bronchiectasis Other Serious 2/25/2010 61 Male 7/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Fungal Hospitalization 51 Male 7/13/2011 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Steatorrhoea Hospitalization 10/1/2004 56 Male 7/13/2011 Other Health Professional United Kingdom
Primary
Secondary
Hypogammaglobulinaemia Other Serious 52 Male 7/13/2011 Other Health Professional United Kingdom
Primary
Secondary
Bronchiectasis Other Serious 61 Male 7/13/2011 Other Health Professional United Kingdom
Primary
Secondary
Cystitis Haemorrhagic Other Serious 17 Male 7/14/2011 Other Health Professional China
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 43 Male 7/14/2011 Other Health Professional China
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 32 Female 7/14/2011 Other Health Professional China
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 38 Male 7/14/2011 Other Health Professional China
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 18 Male 7/14/2011 Physician China
Primary
Concomitant
Chronic Graft Versus Host Disease Other Serious 32 Male 7/14/2011 Other Health Professional China
Primary
Concomitant
Renal Cell Carcinoma Other Serious 62 Male 7/14/2011 Other Health Professional Germany
Primary
Secondary
Bronchiectasis Other Serious 70 Male 7/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Hypergammaglobulinaemia Other Serious 61 Female 7/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Hypogammaglobulinaemia Other Serious 61 Male 7/26/2011 Other Health Professional United Kingdom
Primary
Secondary
Hypogammaglobulinaemia Other Serious 39 Female 7/26/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypogammaglobulinaemia Other Serious 52 Male 7/26/2011 Other Health Professional United Kingdom
Primary
Secondary
Immune Reconstitution Syndrome Hospitalization 1/1/2011 55 Male 8/9/2011 Other Health Professional Japan
Primary
Secondary
Agranulocytosis Hospitalization 5/30/2011 23 Male 8/12/2011 Other Health Professional France
Primary
Secondary
Kaposi's Sarcoma Hospitalization 1/1/2007 33 Male 8/16/2011 Other Health Professional Poland
Primary
Secondary
Posterior Reversible Encephalopathy Syndrome Death 14 Female 8/16/2011 Physician Korea, Republic Of
Primary
Secondary
Opportunistic Infection Death 46 Female 9/8/2011 Other Health Professional United Kingdom
Primary
Secondary
Toxoplasmosis Other Serious 1/1/2007 47 Male 9/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Other Serious 54 Female 11/10/2011 Other Health Professional United States
Primary
Secondary
Graft Dysfunction Hospitalization 68 Male 12/20/2011 Other Health Professional Portugal
Primary
Secondary
Disseminated Cryptococcosis Other Serious 66 Male 12/20/2011 Other Health Professional Portugal
Primary
Secondary
Gingival Hypertrophy Hospitalization 72 Male 1/20/2012 Other Health Professional Poland
Primary
Secondary
Haemolysis Other Serious 18 Male 2/3/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Infection Other Serious 2/7/2012 Physician Romania
Primary
Secondary
Death Other Serious Female 2/9/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Human Herpesvirus 8 Infection Other Serious 51 Female 2/9/2012 Other Health Professional Switzerland
Primary
Secondary
Lymphoproliferative Disorder Other Serious 23 Female 4/3/2012 Other Health Professional Turkey
Primary
Secondary
Bacteraemia Death 46 Male 5/1/2012 Other Health Professional Spain
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death 45 Male 5/9/2012 Other Health Professional Spain
Primary
Secondary
Liver Transplant Rejection Death 10 Female 7/14/2012 Other Health Professional Poland
Primary
Secondary
Pneumonia Bacterial Other Serious 20 Female 7/14/2012 Other Health Professional China
Primary
Secondary
Concomitant
Myopathy Other Serious Female 75 lb 7/17/2012 Physician Thailand
Primary
Concomitant
Thrombocytopenia Hospitalization 60 Male 8/22/2012 Other Health Professional France
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Death 22 Female 8/24/2012 Other Health Professional China
Primary
Secondary
Multi-organ Failure Death 48 Male 8/24/2012 Other Health Professional China
Primary
Secondary
Lung Infection Death 48 Male 8/24/2012 Other Health Professional China
Primary
Secondary
Neutropenia Hospitalization 6/3/2012 4 Male 35 lb 8/24/2012 Physician Germany
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 8/12/2012 50 Female 138 lb 8/16/2012 Pharmacist United States
Primary
Secondary
Off Label Use Hospitalization 42 Male 8/27/2012 Other Health Professional United States
Primary
Concomitant
Forced Expiratory Volume Decreased Other Serious 27 Female 8/27/2012 Other Health Professional Japan
Primary
Concomitant
Toxicity To Various Agents Other Serious 62 Male 8/27/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Osteoporosis Hospitalization 4/1/2012 56 Male 159 lb 8/27/2012 Other Health Professional Germany
Primary
Secondary
Concomitant
Nephrotic Syndrome Hospitalization 20 Male 8/27/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Osteoporosis Hospitalization 4/1/2012 56 Male 159 lb 8/27/2012 Physician Germany
Primary
Secondary
Concomitant

Drug Data