Cyclosporine combined with Methylprednisolone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Transaminases Increased Hospitalization 61 Male 1/11/2006 Physician Germany
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 11/16/1997 50 Male 1/12/2006 Physician Czech Republic
Primary
Concomitant
Kidney Transplant Rejection Other Serious 19 Female 110 lb 1/16/2006 United States
Primary
Concomitant
Interacting
Pseudo Lymphoma Hospitalization 12/4/2002 32 Female 1/16/2006 Physician Japan
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Other Serious 19 Female 110 lb 1/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Other Serious 58 Male 1/21/2006 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/1/2005 49 Male 2/3/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Renal Failure Other Serious 12/1/1999 32 Male 2/2/2006 Japan
Primary
Secondary
Thrombotic Microangiopathy Hospitalization 1 Male 1/25/2006 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 Female 2/11/2006 Physician Netherlands
Primary
Secondary
Concomitant
Tremor Hospitalization 2 Female 2/14/2006 Physician Italy
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 11/19/2005 Female 83 lb 2/28/2006 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious 58 Male 2/21/2006 Physician United States
Primary
Concomitant
Wound Dehiscence Hospitalization 63 Male 3/1/2006 Consumer United Kingdom
Primary
Secondary
Renal Failure Other Serious 12/1/1999 32 Male 3/3/2006 Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 11/19/2005 Female 83 lb 3/3/2006 Physician United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 19 Female 3/4/2006 Physician Korea, Republic Of
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 11/19/2005 Female 83 lb 3/4/2006 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 1/1/2005 59 Male 3/3/2006 Physician Japan
Primary
Secondary
Concomitant
Urinoma Hospitalization 12/31/2003 48 Male 3/17/2006 Physician Germany
Primary
Secondary
Concomitant
Spinal Myelogram Abnormal Other Serious 34 Female 3/21/2006 Physician Japan
Primary
Concomitant
Weight Increased Other Serious 12/1/1999 32 Male 185 lb 3/28/2006 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 61 Male 3/20/2006
Primary
Secondary
White Blood Cell Count Increased Hospitalization 61 Male 3/20/2006
Primary
Secondary
Systemic Candida Death 13 Female 3/29/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Wound Dehiscence Life Threatening 63 Male 3/24/2006 Consumer United Kingdom
Primary
Secondary
White Blood Cell Count Increased Hospitalization 61 Male 3/20/2006 United States
Primary
Secondary
Sepsis Life Threatening 4/19/2005 3 Male 3/31/2006 Consumer United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 1/1/2005 59 Male 3/28/2006 Physician Japan
Primary
Secondary
Concomitant
Somnolence Other Serious 58 Male 3/6/2006 Physician United States
Primary
Concomitant
Urine Analysis Abnormal Other Serious 9/1/2003 26 Male 4/8/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Systemic Candida Death 13 Female 3/31/2006 Physician Japan
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 26 Male 4/12/2006 Physician United Kingdom
Primary
Concomitant
Transplant Rejection Other Serious 44 Male 4/12/2006 Physician United Kingdom
Primary
Concomitant
Sepsis Other Serious 1/10/2006 38 Male 176 lb 4/5/2006 Physician United States
Primary
Concomitant
Sepsis Life Threatening 4/19/2005 3 Male 4/14/2006 Consumer United States
Primary
Secondary
Concomitant
Vasculitis Necrotising Death 63 Male 4/5/2006 Other Health Professional Belgium
Primary
Secondary
Renal Failure Acute Other Serious 12/6/2005 51 Female 128 lb 4/24/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2001 40 Female 115 lb 4/26/2006 Japan
Primary
Secondary
Platelet Count Decreased Other Serious 11/18/2003 58 Male 123 lb 4/26/2006 Japan
Primary
Concomitant
Thyroid Disorder Hospitalization 63 Male 4/20/2006
Primary
Secondary
Concomitant
Septic Shock Death 40 Female 115 lb 4/28/2006 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 9/15/2005 43 Male 5/10/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Tachycardia Hospitalization 59 Male 5/10/2006 Other Health Professional Austria
Primary
Secondary
Concomitant
Viral Dna Test Positive Hospitalization 10 Male 5/10/2006 Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 40 Female 115 lb 4/28/2006 Physician Japan
Primary
Concomitant
Shock Other Serious 2/1/2005 75 Male 165 lb 5/15/2006 Physician Germany
Primary
Secondary
Drug Level Increased Hospitalization 4/10/2006 14 Female 73 lb 5/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Viral Dna Test Positive Hospitalization 10 Male 5/23/2006 Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 1/1/2001 40 Female 115 lb 5/31/2006 Japan
Primary
Secondary
Necrosis Ischaemic Hospitalization 5/22/2006 48 Female 5/31/2006 Italy
Primary
Concomitant
Renal Necrosis Other Serious 5/22/2006 48 Female 6/1/2006 Italy
Primary
Concomitant
Transplant Rejection Other Serious 36 Male 6/12/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/1/2006 53 Male 6/13/2006 Physician Germany
Primary
Concomitant
Graft Versus Host Disease Death 3/28/2003 31 Male 4/27/2006 Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2006 53 Male 6/15/2006 Physician Germany
Primary
Concomitant
Transplant Rejection Other Serious 36 Male 6/10/2006 Physician Switzerland
Primary
Secondary
Concomitant
Kidney Transplant Rejection Other Serious 11/30/2005 44 Male 6/20/2006 Italy
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 64 6/22/2006 Physician Italy
Primary
Secondary
Rhabdomyolysis Hospitalization 1/1/2006 53 Male 6/28/2006 Physician Germany
Primary
Concomitant
Malaise Hospitalization 1/1/2005 12 Female 6/30/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Recurrent Cancer Other Serious 6/1/2005 42 Male 6/27/2006 Physician New Zealand
Primary
Concomitant
Neutrophil Morphology Abnormal Other Serious 44 Male 7/5/2006 Physician United Kingdom
Primary
Concomitant
Vascular Skin Disorder Other Serious 35 Male 7/6/2006 Other Health Professional Poland
Primary
Secondary
Diverticulitis Hospitalization 53 Female 7/6/2006 Germany
Primary
Secondary
Renal Necrosis Other Serious 6 Female 6/30/2006 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Atrophy Other Serious 41 Male 6/30/2006 Colombia
Primary
Secondary
Concomitant
Vascular Skin Disorder Other Serious 35 Male 7/6/2006 Physician Poland
Primary
Secondary
Pyelonephritis Acute Other Serious 43 Female 7/11/2006 Physician Korea, Republic Of
Primary
Secondary
Red Blood Cell Sedimentation Rate Increased Other Serious 26 Male 7/12/2006 Physician Turkey
Primary
Secondary
Urethral Haemorrhage Other Serious 1/1/2000 39 Male 7/20/2006 Other Health Professional Finland
Primary
Secondary
Respiratory Disorder Death 36 Male 7/24/2006 Japan
Primary
Secondary
Skin Papilloma Hospitalization 6/2/2004 54 Female 7/18/2006 Physician Japan
Primary
Secondary
Renal Cell Carcinoma Stage Unspecified Other Serious 6 Female 7/13/2006 United States
Primary
Secondary
Visual Field Defect Other Serious Female 7/13/2006
Primary
Secondary
Concomitant
Respiratory Disorder Death 36 Male 7/26/2006 Japan
Primary
Secondary
Haemangioma Other Serious 35 Male 7/27/2006 Other Health Professional Poland
Primary
Secondary
Urethral Haemorrhage Other Serious 1/1/2000 39 Male 7/19/2006 Physician Finland
Primary
Secondary
Respiratory Disorder Death 36 Male 8/1/2006 Japan
Primary
Secondary
Pneumonia Death 36 Male 7/21/2006 Physician Japan
Primary
Secondary
Pancreatitis Life Threatening 8/21/2005 38 Female 136 lb 8/1/2006 Pharmacist United States
Primary
Concomitant
Respiratory Disorder Death 36 Male 7/26/2006 Physician Japan
Primary
Secondary
Rhabdomyolysis Hospitalization 1/1/2006 53 Male 8/4/2006 Physician Germany
Primary
Concomitant
Septic Shock Other Serious 1/1/2002 64 Male 8/3/2006 Japan
Primary
Secondary
Concomitant
Pneumonia Death 36 Male 8/1/2006 Physician Japan
Primary
Secondary
Fungal Sepsis Death 8/2/2006
Primary
Concomitant
White Blood Cell Count Increased Other Serious 53 Female 8/9/2006 Physician Germany
Primary
Secondary
Vomiting Other Serious 17 Female 8/15/2006 Other Health Professional India
Primary
Secondary
Septic Shock Other Serious 1/1/2002 64 Male 8/3/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 17 Female 8/15/2006 Other Health Professional India
Primary
Secondary
Diverticulitis Hospitalization 53 Female 8/18/2006 Germany
Primary
Secondary
Vanishing Bile Duct Syndrome Other Serious 45 Female 8/22/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Other Serious 60 Female 8/22/2006 Other Health Professional Germany
Primary
Secondary
Vomiting Other Serious 17 Female 8/15/2006 Physician India
Primary
Secondary
Diverticulitis Hospitalization 1/1/2006 53 Female 8/16/2006 Physician Germany
Primary
Secondary
Renal Impairment Other Serious 12/20/2004 44 Male 8/23/2006 Japan
Primary
Secondary
Stem Cell Transplant Other Serious 1/26/2005 41 Female 132 lb 8/17/2006 Physician Canada
Primary
Concomitant
Renal Failure Other Serious 60 Female 8/22/2006 Physician Germany
Primary
Secondary
Vanishing Bile Duct Syndrome Other Serious 45 Female 8/22/2006 Physician Germany
Primary
Secondary
Concomitant
Renal Impairment Other Serious 12/20/2004 44 Male 8/22/2006 Physician Japan
Primary
Secondary
Surgery Other Serious 7/1/1996 59 Male 8/29/2006 Other Health Professional Czech Republic
Primary
Secondary
Vomiting Death 7/28/2006 4 Male 39 lb 8/22/2006 Physician China
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 10 Female 9/1/2006 Spain
Primary
Concomitant
Therapy Non-responder Other Serious 35 Male 8/24/2006
Primary
Secondary
Therapeutic Agent Toxicity Other Serious 7/1/1996 59 Male 8/29/2006 Physician Czech Republic
Primary
Secondary
Venoocclusive Liver Disease Life Threatening 4/19/2005 3 Male 9/8/2006 Consumer United States
Primary
Concomitant
Staphylococcal Infection Other Serious 57 Male 9/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Ulcer Other Serious 57 Male 9/1/2006 Other Health Professional United Kingdom
Primary
Secondary
Sepsis Life Threatening 4/19/2005 3 Male 9/20/2006 Consumer United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 6/30/2003 52 Male 9/27/2006
Primary
Secondary
Trichosporon Infection Death 42 Male 10/9/2006 Japan
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 1/1/2004 41 Female 10/7/2006 Japan
Primary
Secondary
Concomitant
Renal Tubular Atrophy Other Serious 18 Female 10/11/2006 Germany
Primary
Secondary
Concomitant
Toxic Induced Encephalopathy Other Serious 1/1/2003 Male 10/17/2006 Japan
Primary
Concomitant
Melaena Other Serious 1/1/2004 41 Female 10/17/2006 Japan
Primary
Secondary
Concomitant
Trichosporon Infection Death 42 Male 10/17/2006 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 3/1/2006 53 Male 10/31/2006 Other Health Professional Germany
Primary
Concomitant
Vomiting Hospitalization 9/27/2005 61 Female 88 lb 10/26/2006 Physician France
Primary
Secondary
Infection Death 11/4/2006
Primary
Concomitant
Infection Death 11/4/2006
Primary
Concomitant
Infection Death 11/4/2006
Primary
Concomitant
Infection Death 11/4/2006
Primary
Concomitant
Infection Death 11/4/2006
Primary
Concomitant
Infection Death 11/4/2006
Primary
Concomitant
Intestinal Ischaemia Death 11/4/2006
Primary
Concomitant
Respiratory Failure Death 11/4/2006
Primary
Concomitant
Hepatic Artery Thrombosis Death 11/4/2006
Primary
Concomitant
Hepatic Artery Thrombosis Death 11/4/2006
Primary
Concomitant
Graft Dysfunction Death 11/4/2006
Primary
Concomitant
Graft Dysfunction Death 11/4/2006
Primary
Concomitant
Neoplasm Malignant Life Threatening 11/4/2006
Primary
Concomitant
Hepatitis C Virus Death 11/4/2006
Primary
Concomitant
Kaposi's Sarcoma Other Serious 11/1/2002 49 Female 11/1/2006 Physician Australia
Primary
Concomitant
Tuberculosis Other Serious 6/1/1994 38 Male 11/15/2006 Other Health Professional Turkey
Primary
Secondary
Concomitant
Thrombophlebitis Other Serious 1/1/2003 34 Female 11/21/2006 Japan
Primary
Concomitant
Vomiting Hospitalization 9/27/2005 61 Female 88 lb 11/14/2006 Physician France
Primary
Secondary
Varices Oesophageal Other Serious 5/1/2006 41 Male 11/29/2006 Physician France
Primary
Secondary
Concomitant
Upper Limb Fracture Hospitalization 4/13/2006 Female 115 lb 12/1/2006 Physician Italy
Primary
Concomitant
Rash Papular Other Serious 8/1/2002 49 Female 11/22/2006 Physician Australia
Primary
Secondary
Concomitant
Rash Other Serious 1 Female 12/8/2006 Japan
Primary
Secondary
Renal Vein Thrombosis Hospitalization 8/18/2006 19 Male 12/12/2006 Consumer United States
Primary
Concomitant
Varices Oesophageal Other Serious 5/1/2006 41 Male 12/12/2006 Physician France
Primary
Secondary
Concomitant
Proteinuria Other Serious 9 Male 12/19/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Proteinuria Other Serious 11 Female 12/19/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Metastases To Central Nervous System Other Serious 51 Female 12/19/2006 Other Health Professional Spain
Primary
Concomitant
Renal Failure Other Serious 32 Male 12/19/2006 Other Health Professional Spain
Primary
Concomitant
Respiratory Failure Other Serious 1/26/2005 41 Female 132 lb 12/4/2006 Other Health Professional Canada
Primary
Concomitant
Upper Limb Fracture Hospitalization 4/13/2006 Female 115 lb 12/21/2006 Physician Italy
Primary
Concomitant
Rash Other Serious 1 Female 12/23/2006 Japan
Primary
Secondary
Non-hodgkin's Lymphoma Other Serious 6/1/2005 6 Male 12/22/2006 Physician Japan
Primary
Secondary

Drug Data