Cyclosporine combined with Levofloxacin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urinoma Hospitalization 12/31/2003 48 Male 3/17/2006 Physician Germany
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 4/23/2005 50 Male 126 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 6/5/2002 42 Female 112 lb 5/15/2006 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Hospitalization 3/17/2006 61 Male 6/2/2006 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 6/5/2002 42 Female 112 lb 6/7/2006 Physician Japan
Primary
Secondary
Concomitant
Proteinuria Hospitalization 8/11/2003 30 Male 6/14/2006 Japan
Primary
Concomitant
Urinary Tract Infection Enterococcal Other Serious 1/1/2005 23 Male 7/19/2006 Physician United States
Primary
Concomitant
Eyelid Infection Other Serious 4/1/2003 60 Female 8/8/2006 Japan
Primary
Concomitant
Renal Tubular Acidosis Other Serious 5/5/2005 20 Male 8/30/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/2/2006 40 Male 9/1/2006 Other Health Professional United States
Primary
Concomitant
Venoocclusive Liver Disease Required Intervention 55 Female 10/5/2006 Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/2/2006 40 Male 10/14/2006 Other Health Professional United States
Primary
Concomitant
Vomiting 2/8/2006 36 Male Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious Female 1/23/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Urinary Tract Obstruction Hospitalization 62 Male 4/24/2007 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious Unknown 4/16/2007 Germany
Primary
Secondary
White Blood Cell Count Decreased Other Serious 3/2/2006 40 Male 5/5/2007 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Other Serious 1/1/2005 Female 6/1/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 1/1/2005 Female 6/19/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 10/24/2006 41 Male 151 lb 10/24/2006 United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 2/9/2007 57 Female Physician United States
Primary
Concomitant
Viral Infection Death 11/30/2007 51 Female 106 lb 12/28/2007 Physician Belgium
Primary
Concomitant
Vomiting 2/9/2007 57 Female 5/2/2008 Physician United States
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 9/1/2006 18 Male 8/6/2008 Physician Japan
Primary
Secondary
Pancytopenia Life Threatening 1/31/2008 Male 8/6/2008 Physician Japan
Primary
Concomitant
Vomiting Other Serious 7/14/2005 8/19/2008 United States
Primary
Secondary
Concomitant
Fungal Rhinitis Other Serious 41 Male 7/8/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 9/1/2006 Male 10/20/2008 Physician Japan
Primary
Secondary
Concomitant
Impaired Gastric Emptying Hospitalization 10/7/2008 Male 11/12/2008 Pharmacist United States
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 4/1/2008 60 Female 177 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Required Intervention 6/5/2008 63 Female 256 lb 12/26/2008 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 6/9/2008 60 Male 249 lb 12/22/2008 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 6/9/2008 60 Male 249 lb 1/13/2009 Physician United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 67 Male 2/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vesicoureteric Reflux Hospitalization 3/2/2004 Female 4/2/2009 Physician Turkey
Primary
Concomitant
Death Death 2/1/2004 Female 4/3/2009 Physician Israel
Primary
Secondary
Concomitant
Shunt Thrombosis Hospitalization 12/8/2003 Male 4/8/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 12/9/2007 4/17/2009 Physician Egypt
Primary
Concomitant
Hepatic Function Abnormal Other Serious 12/9/2007 5/4/2009 Physician Egypt
Primary
Concomitant
Septic Shock Other Serious 11/30/2007 50 Female 119 lb 5/22/2009 Physician Belgium
Primary
Concomitant
Shock Haemorrhagic Life Threatening 1/13/2004 Female 196 lb 6/23/2009 Physician Israel
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 5/20/2003 Male 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Transplant Failure Hospitalization 1/22/2006 Male 209 lb 6/23/2009 Physician Spain
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 11/13/2003 Female 6/26/2009 Physician Spain
Primary
Concomitant
Shock Haemorrhagic Life Threatening 1/13/2004 50 Female 7/31/2009 Physician Israel
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 8/31/2009 54 Female 110 lb 9/8/2009 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 1/31/2008 Male 9/10/2009 Japan
Primary
Concomitant
Thrombocytopenia Other Serious 8/31/2009 54 Female 110 lb 9/11/2009 Physician United States
Primary
Secondary
Concomitant
Viral Infection Hospitalization 6/1/2009 55 Female 198 lb 9/21/2009 Other Health Professional United States
Primary
Concomitant
Plasmacytoma Hospitalization 8/16/2009 64 Male 9/11/2009 Other Health Professional United States
Primary
Concomitant
Stem Cell Transplant Other Serious 8/16/2009 64 Male 9/21/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 5/20/2009 19 Male 146 lb 9/16/2009 Physician India
Primary
Concomitant
Plasmacytoma Hospitalization 8/16/2009 64 Male 9/24/2009 Other Health Professional United States
Primary
Concomitant
Serum Sickness Other Serious 5/20/2009 19 Male 146 lb 10/1/2009 Physician India
Primary
Concomitant
Plasmacytoma Hospitalization 8/16/2009 64 Male 10/7/2009 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 33 Male 10/16/2009 Physician India
Primary
Concomitant
Sepsis Death 8/1/2009 83 Male 137 lb 11/9/2009 Physician Japan
Primary
Concomitant
Tremor Hospitalization 8/16/2009 64 Male 11/23/2009 Other Health Professional United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 50 Female 12/7/2009 Japan
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 56 Male 12/7/2009 Japan
Primary
Secondary
Concomitant
Multi-organ Failure Death 10/1/2009 52 Male 12/22/2009 Physician Japan
Primary
Concomitant
No Therapeutic Response Death 7/31/2009 76 Male 121 lb 12/14/2009 Physician Japan
Primary
Concomitant
Tremor Hospitalization 8/16/2009 64 Male 12/21/2009 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 6/10/2009 Female 104 lb 3/4/2010 Physician Japan
Primary
Concomitant
Heart Rate Increased Other Serious 11/5/2009 47 Female 3/5/2010 Consumer Japan
Primary
Concomitant
Treatment Related Secondary Malignancy Death 63 Male 3/1/2010 Physician Spain
Primary
Concomitant
Vasogenic Cerebral Oedema Death 63 Male 3/11/2010 Physician Spain
Primary
Concomitant
Renal Impairment Life Threatening 1/31/2008 Male 3/19/2010 Japan
Primary
Concomitant
Interacting
Pyrexia Other Serious 4/6/2010 39 Male 143 lb 5/25/2010 Consumer Japan
Primary
Concomitant
Pyrexia Other Serious 4/6/2010 39 Male 143 lb 6/11/2010 Consumer Japan
Primary
Concomitant
Heart Rate Increased Other Serious 11/5/2009 47 Female 7/6/2010 Consumer Japan
Primary
Concomitant
Respiratory Disorder Death 7/31/2009 76 Male 121 lb 6/28/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Death 1/23/2010 72 Female 143 lb 8/4/2010 Consumer Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/9/2009 58 Female 97 lb 7/28/2010 Physician Japan
Primary
Concomitant
Pneumonia Death 1/18/2010 77 Female 104 lb 8/26/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 6/10/2009 74 Female 104 lb 9/24/2010 Physician Japan
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 10/7/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 1/5/2010 58 Male 176 lb 10/15/2010 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 11/2/2009 68 Female 106 lb 10/26/2010 Physician Japan
Primary
Concomitant
Fungaemia Death 6/22/2005 46 Male 126 lb 11/15/2010 Physician Japan
Primary
Secondary
Concomitant
Encephalitis Fungal Death Male 139 lb 11/15/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 12/17/2009 73 Female 117 lb 11/15/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 6/12/2010 12/1/2010 Consumer Japan
Primary
Concomitant
Stenotrophomonas Sepsis Life Threatening 10/18/2010 69 Female 115 lb 12/1/2010 Physician Japan
Primary
Concomitant
Stenotrophomonas Sepsis Life Threatening 10/18/2010 69 Female 115 lb 12/8/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
Pneumonia Death 2/1/2010 77 Female 104 lb 12/13/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
Enterococcal Sepsis Death 11 Female 12/17/2010 Physician Italy
Primary
Secondary
Concomitant
Hiccups Death 7/30/2010 49 Male 110 lb 12/17/2010 Physician Japan
Primary
Secondary
Concomitant
Stenotrophomonas Sepsis Hospitalization 10/18/2010 69 Female 115 lb 12/20/2010 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Hospitalization 4/12/2010 61 Male 152 lb 12/21/2010 Physician Japan
Primary
Concomitant
Pancytopenia Death 11 Female 12/21/2010 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/12/2009 76 Male 119 lb 12/23/2010 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Death 10/20/2010 62 Female 119 lb 12/27/2010 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Other Serious 3/19/2010 31 Male 139 lb 12/27/2010 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Other Serious 11/11/2009 72 Female 126 lb 12/27/2010 Physician Japan
Primary
Concomitant
Urinary Tract Infection Bacterial Death 3/25/2010 58 Male 150 lb 12/29/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening 12/12/2009 76 Male 119 lb 12/29/2010 Physician Japan
Primary
Concomitant
Pyrexia Death 3/25/2010 58 Male 150 lb 12/29/2010 Physician Japan
Primary
Concomitant
Hypertension Hospitalization 3/20/2010 71 Female 106 lb 12/30/2010 Physician Japan
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 5/17/2010 50 Male 161 lb 1/4/2011 Physician Japan
Primary
Concomitant
Atrial Fibrillation Hospitalization 4/11/2009 70 Male 119 lb 1/7/2011 Physician Japan
Primary
Concomitant
Pseudomonal Sepsis Hospitalization 8/17/2009 54 Female 108 lb 1/7/2011 Consumer Japan
Primary
Concomitant
Chronic Graft Versus Host Disease Other Serious 25 Female 3/9/2011 Physician Japan
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 3/9/2011 Physician Japan
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 46 Male 3/9/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatitis Fulminant Other Serious 58 Female 3/9/2011 Physician Japan
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 18 Female 3/28/2011 Physician Japan
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 25 Female 3/28/2011 Physician Japan
Primary
Secondary
Concomitant
Epstein-barr Virus Infection Hospitalization 4/12/2010 61 Male 152 lb 3/30/2011 Physician Japan
Primary
Concomitant
Abdominal Pain Other Serious 12/17/2009 73 Female 117 lb 4/5/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 9/20/2010 77 Female 101 lb 4/7/2011 Physician Japan
Primary
Concomitant
Hepatitis Fulminant Other Serious 58 Female 4/13/2011 Physician Japan
Primary
Secondary
Concomitant
Insomnia Hospitalization 11/2/2009 68 Female 106 lb 5/18/2011 Physician Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Death 7/30/2010 49 Male 110 lb 5/20/2011 Physician Japan
Primary
Secondary
Concomitant
Petechiae Other Serious 1/29/2010 49 Male 110 lb 5/20/2011 Physician Japan
Primary
Concomitant
Pneumonia Life Threatening 4/28/2010 56 Male 139 lb 5/23/2011 Physician Japan
Primary
Concomitant
Renal Disorder Life Threatening 7/25/2010 60 Female 93 lb 5/24/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Death 8/31/2010 56 Male 159 lb 5/27/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Death 8/31/2010 56 Male 159 lb 6/7/2011 Physician Japan
Primary
Concomitant
Nasopharyngitis Hospitalization 9/3/2004 62 Male 6/6/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 2/1/2004 60 Female 5/31/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 12/20/2003 27 Female 108 lb 6/16/2011 Physician Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Death 7/30/2010 49 Male 110 lb 6/16/2011 Physician Japan
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Hospitalization 5/7/2009 62 Male 126 lb 6/8/2011 Physician Japan
Primary
Concomitant
Constipation Hospitalization 12/10/2003 27 Female 108 lb 6/24/2011 Physician Japan
Primary
Secondary
Concomitant
Lung Disorder Life Threatening 4/28/2010 56 Male 139 lb 7/8/2011 Physician Japan
Primary
Concomitant
Cough Death 55 Female 7/13/2011 Other Health Professional Italy
Primary
Concomitant
Encephalitis Other Serious 10/20/2010 62 Female 119 lb 7/20/2011 Physician Japan
Primary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 12/10/2003 27 Female 108 lb 7/21/2011 Physician Japan
Primary
Secondary
Concomitant
Enterococcal Sepsis Hospitalization 11/4/2010 77 Male 110 lb 7/22/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Infection Other Serious 6/18/2010 39 Female 110 lb 7/22/2011 Physician Japan
Primary
Secondary
Concomitant
Bacterial Sepsis Hospitalization 3/19/2010 31 Male 139 lb 7/29/2011 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Death 11/3/2010 45 Male 104 lb 7/29/2011 Physician Japan
Primary
Concomitant
Encephalitis Fungal Death Male 139 lb 8/1/2011 Physician Japan
Primary
Secondary
Concomitant
Fungaemia Death 6/22/2005 46 Male 126 lb 8/2/2011 Physician Japan
Primary
Secondary
Concomitant
Disease Recurrence Other Serious 6/13/2011 62 Female 1360 lb 8/12/2011 Other Health Professional United States
Primary
Concomitant
Multi-organ Failure Death 3/1/2007 22 Female 99 lb 8/18/2011 Physician Japan
Primary
Secondary
Concomitant
Dizziness Hospitalization 9/27/2010 8/22/2011 Physician Japan
Primary
Concomitant
Atrial Fibrillation Hospitalization 9/20/2010 77 Female 101 lb 8/30/2011 Physician Japan
Primary
Concomitant
Haematochezia Other Serious 51 Female 132 lb 9/14/2011 Other Health Professional Japan
Primary
Concomitant
Interacting
Generalised Oedema Death 5/6/2011 51 Female 132 lb 9/19/2011 Japan
Primary
Concomitant
Interacting
C-reactive Protein Increased Death 1/18/2006 35 Male 110 lb 9/20/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Life Threatening 11/17/2010 9/21/2011 Physician Japan
Primary
Concomitant
Febrile Neutropenia Life Threatening 9/2/2010 57 Female 115 lb 9/23/2011 Physician Japan
Primary
Concomitant
Delirium Other Serious 70 Female 9/26/2011 Physician United States
Primary
Secondary
Concomitant
Pseudomembranous Colitis Life Threatening 3/5/2011 80 Female 132 lb 10/3/2011 Physician Japan
Primary
Concomitant
Decreased Appetite Hospitalization 6/20/2011 46 Male 10/10/2011 United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 17 Male 10/12/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant

Drug Data