Cyclosporine combined with Itraconazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tremor Life Threatening 11/22/2004 31 Female 1/9/2006 Physician Japan
Primary
Secondary
Concomitant
Tracheostomy Life Threatening 7/10/2005 42 Female 1/23/2006 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/3/2005 61 Female 132 lb 2/23/2006 Consumer Australia
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 1/1/2005 59 Male 3/3/2006 Physician Japan
Primary
Secondary
Concomitant
Fungal Infection Life Threatening Female 3/8/2006 Physician France
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 1/1/2005 59 Male 3/20/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 20 Male 4/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 20 Male 146 lb 3/31/2006 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 4/23/2005 50 Male 126 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Oral Infection Hospitalization 28 Female 4/21/2006
Primary
Secondary
Ulcer Other Serious 1/1/2003 64 Male 5/9/2006 Australia
Primary
Concomitant
Paralysis Death 28 Female 5/26/2006 Germany
Primary
Secondary
Concomitant
Splenic Infarction Hospitalization 45 Male 7/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 4/1/2000 53 Male 7/21/2006 Other Health Professional Greece
Primary
Secondary
Concomitant
Kaposi's Sarcoma Other Serious 11/1/2002 49 Female 11/1/2006 Physician Australia
Primary
Concomitant
Rash Papular Other Serious 8/1/2002 49 Female 11/22/2006 Physician Australia
Primary
Secondary
Concomitant
Pancreatitis Haemorrhagic Hospitalization 5 Female 1/9/2007 Consumer Australia
Primary
Secondary
Concomitant
Pancreatitis Haemorrhagic Hospitalization 5 Female 1/8/2007 Australia
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 27 Female 4/17/2007 Japan
Primary
Secondary
Concomitant
Transplant Rejection Death 5/16/2006 49 Female 109 lb 4/29/2007 Physician Japan
Primary
Concomitant
Pancreatitis Haemorrhagic Hospitalization 5 Female 5/22/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Sepsis Other Serious 2 Male 5/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 1/1/2005 27 Female 6/19/2007 Japan
Primary
Secondary
Concomitant
Pseudomembranous Colitis Other Serious 11/17/2006 45 Male 6/25/2007 Japan
Primary
Secondary
Concomitant
Tremor 7/18/2007 59 Female 153 lb 7/24/2007 Pharmacist United States
Primary
Concomitant
Viraemia Other Serious 12 Male 9/21/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Creatinine Renal Clearance Decreased Other Serious 53 Female 1/16/2008 Physician Japan
Primary
Concomitant
Graft Versus Host Disease Death 33 Male 2/15/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 53 Male 2/18/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Death 15 Male 2/18/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 27 Female 2/18/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
No Therapeutic Response Death 33 Male 2/19/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Death 15 Male 2/20/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 53 Male 2/20/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 27 Female 2/20/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Death 57 Male 2/20/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 12/30/2007 5 Male 42 lb 4/3/2008 Physician Belgium
Primary
Concomitant
Transaminases Increased Hospitalization 12/30/2007 5 Male 42 lb 4/7/2008 Physician Belgium
Primary
Concomitant
Trismus Death 45 Male 4/21/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 9/1/2007 50 Female 82 lb 4/30/2008 Physician Japan
Primary
Concomitant
Urinary Incontinence Other Serious 45 Male 4/25/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/13/2008 47 Male 141 lb 5/14/2008 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Death 7/17/2007 65 Male 161 lb 5/20/2008 Physician Japan
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/6/2008
Primary
Secondary
Concomitant
Aspergillosis Other Serious 43 Male 6/18/2008
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/18/2008
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 48 Male 6/20/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 31 Male 7/18/2008
Primary
Secondary
Concomitant
Supraventricular Extrasystoles Other Serious 11 Male 51 lb 4/8/2008 Other Health Professional China
Primary
Secondary
Concomitant
Trichosporon Infection Death 4/15/2008 53 Male 123 lb 12/5/2008 Physician Japan
Primary
Concomitant
Sinusitis Hospitalization 1/1/2007 60 Male 143 lb 12/16/2008 Physician Spain
Primary
Secondary
Concomitant
Sinusitis Hospitalization 1/1/2007 60 Male 143 lb 12/19/2008 Physician Spain
Primary
Secondary
Concomitant
Pancreatitis Other Serious 1/16/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Tachyarrhythmia Other Serious 57 Female 2/12/2009 Other Health Professional Germany
Primary
Concomitant
Pancreatitis Haemorrhagic Hospitalization 2/11/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/27/2009 59 Male 2/25/2009 Other Health Professional Spain
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/12/2003 0 Male 13 lb 3/19/2009 France
Primary
Secondary
Concomitant
Lung Disorder Death 1/1/2008 49 Male 3/31/2009 Other Health Professional Japan
Primary
Concomitant
Staphylococcal Infection Other Serious 2/1/2009 59 Male 3/26/2009 Other Health Professional Spain
Primary
Concomitant
Renal Impairment Other Serious 75 Male 4/2/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 12/30/2007 5 Male 42 lb 4/6/2009 Physician Belgium
Primary
Concomitant
Pneumonia Other Serious 5/27/2008 4/20/2009 Physician Egypt
Primary
Secondary
Concomitant
Sepsis Other Serious 24 Female 4/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Multi-organ Failure Death 20 5/4/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Systemic Mycosis Death 17 5/7/2009 United Kingdom
Primary
Secondary
Concomitant
Engraft Failure Other Serious 5 5/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 16 5/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Resistance Death 17 5/8/2009 United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Other Serious 1 5/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 8 Male 5/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Engraft Failure Other Serious 5 5/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 16 5/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Systemic Mycosis Death 17 5/12/2009 United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 16 5/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Death 17 5/7/2009 United Kingdom
Primary
Secondary
Concomitant
Systemic Mycosis Death 17 5/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 16 5/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 16 5/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 16 5/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vascular Injury Hospitalization 19 5/21/2009 United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection 16 5/21/2009 United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia 8 Male 5/21/2009 United Kingdom
Primary
Concomitant
Procedural Complication 5 5/21/2009 France
Primary
Concomitant
Drug Ineffective Other Serious 3 6/1/2009 Physician United Kingdom
Primary
Secondary
Pneumonitis Other Serious 19 6/3/2009 Other Health Professional United Kingdom
Primary
Secondary
Systemic Mycosis Death 17 6/4/2009 United Kingdom
Primary
Secondary
Concomitant
Systemic Mycosis Death 17 6/5/2009 United Kingdom
Primary
Secondary
Concomitant
Tracheostomy Malfunction Hospitalization 19 6/5/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Obliterative Bronchiolitis 4 6/3/2009 France
Primary
Concomitant
Bile Duct Stenosis Other Serious 4 6/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Anti-thyroid Antibody Positive Other Serious 3 6/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Acute Graft Versus Host Disease In Skin Other Serious 1 6/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Cytomegalovirus Infection Other Serious 8 6/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Acute Graft Versus Host Disease Other Serious 2 6/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Hyperthyroidism Other Serious 14 6/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Virus Serology Test Positive Death 4/17/2009 58 Female 97 lb 6/2/2009 Physician Japan
Primary
Concomitant
Pancreatitis Other Serious 5 Female 6/10/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Hyperthyroidism Other Serious 14 6/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Hypothyroidism Other Serious 16 6/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Upper Respiratory Tract Infection Other Serious 16 6/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 2 6/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Systemic Mycosis Death 17 6/12/2009 United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant 21 6/12/2009 United Kingdom
Primary
Secondary
Anti-thyroid Antibody Positive 3 6/18/2009 France
Primary
Concomitant
Systemic Mycosis Death 17 6/23/2009 United Kingdom
Primary
Secondary
Concomitant
Vital Capacity Decreased 21 6/26/2009 United Kingdom
Primary
Secondary
Pyrexia Other Serious 6/1/2009 55 Female 121 lb 6/30/2009 Physician Japan
Primary
Concomitant
Hypertensive Crisis Other Serious 49 Male 7/15/2009 Other Health Professional Brazil
Primary
Interacting
Hepatitis Cholestatic Other Serious 56 Male 7/16/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Renal Failure Acute Death 6/9/2009 56 Female 130 lb 7/8/2009 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 6/1/2009 65 Female 93 lb 7/9/2009 Physician Japan
Primary
Concomitant
Virus Serology Test Positive Death 4/17/2009 58 Female 97 lb 7/10/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 6/1/2009 55 Female 121 lb 7/20/2009 Physician Japan
Primary
Concomitant
Malaise Hospitalization 6/8/2009 27 Male 7/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 16 8/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 4/1/2009 70 Female 144 lb 8/7/2009 Physician United Kingdom
Primary
Concomitant
Graft Versus Host Disease Death 9/9/2008 Male 168 lb 9/9/2009 Physician United Kingdom
Primary
Concomitant
Viral Infection Other Serious 9/16/2009 Consumer United Kingdom
Primary
Secondary
Therapeutic Response Decreased Hospitalization 1/1/2009 65 Female 108 lb 9/2/2009 Physician Japan
Primary
Concomitant
Sepsis Death 4/30/2009 71 Female 152 lb 9/3/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 8/11/2009 38 Female 134 lb 9/21/2009 Physician Japan
Primary
Concomitant
Cardiac Failure Acute Death 8/4/2009 74 Male 132 lb 9/17/2009 Physician Japan
Primary
Concomitant
Viral Infection Other Serious 10/15/2009 Consumer United Kingdom
Primary
Secondary
Drug Interaction Other Serious 9/24/2009 2 10/21/2009 Other Health Professional United Kingdom
Primary
Interacting
Drug Interaction Other Serious 2 10/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Transaminases Increased Other Serious 10/26/2009 Consumer United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Death 4/30/2009 71 Female 152 lb 10/28/2009 Physician Japan
Primary
Concomitant
Pancytopenia Other Serious 7/31/2009 74 Male 134 lb 11/2/2009 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction 2 Unknown 11/12/2009 France
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 4/29/2009 65 Female 108 lb 11/5/2009 Physician Japan
Primary
Concomitant
Sepsis Death 8/1/2009 83 Male 137 lb 11/9/2009 Physician Japan
Primary
Concomitant
Multi-organ Failure Death 10/1/2009 52 Male 12/22/2009 Physician Japan
Primary
Concomitant
Supraventricular Tachycardia Other Serious 5/27/2009 68 Female 104 lb 12/23/2009 Physician Japan
Primary
Concomitant
Renal Failure Acute Life Threatening 6/9/2009 56 Female 130 lb 12/17/2009 Physician Japan
Primary
Concomitant
Stem Cell Transplant Hospitalization 6/8/2009 27 Male 12/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Septic Embolus Other Serious 24 Female 1/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 24 Female 1/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Sepsis Death 24 Female 2/8/2010 United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious 4/20/2009 25 Male 126 lb 2/9/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Death 19 Female 2/10/2010 Other Health Professional United Kingdom
Primary
Secondary
No Therapeutic Response Death 10/1/2009 52 Male 132 lb 1/29/2010 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 8/17/2009 70 Female 150 lb 1/28/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/10/2009 Female 104 lb 3/4/2010 Physician Japan
Primary
Concomitant
Stem Cell Transplant Other Serious 6/8/2009 27 Male 2/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypotension Life Threatening 10/13/2009 28 Male 3/10/2010 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Tachycardia Life Threatening 3/3/2010 45 Female 240 lb 3/26/2010 Consumer United Kingdom
Primary
Concomitant
Stem Cell Transplant Other Serious 6/8/2009 27 Male 3/17/2010 United Kingdom
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 4/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pseudomonal Sepsis Other Serious 4/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Obliterative Bronchiolitis Other Serious 4/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data