Cyclosporine combined with Heparin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urinary Retention Hospitalization 8/1/2005 55 Male 1/5/2006 Pharmacist United States
Primary
Concomitant
Thrombophlebitis Hospitalization 5/14/2005 33 Male 2/7/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 5/14/2005 33 Male 2/10/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 4/19/2005 3 Male 3/31/2006 Consumer United States
Primary
Concomitant
Sepsis Life Threatening 4/19/2005 3 Male 4/14/2006 Consumer United States
Primary
Secondary
Concomitant
Wrong Drug Administered Required Intervention 9/8/2005 62 Male 163 lb 2/9/2006 United States
Primary
Concomitant
Graft Versus Host Disease Death 3/28/2003 31 Male 4/27/2006 Japan
Primary
Concomitant
Streptococcal Infection Other Serious 1/1/2003 55 Female 6/13/2006 France
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 1/26/2005 41 Female 132 lb 8/17/2006 Physician Canada
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2004 Male 146 lb 9/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious Male 9/7/2006 Physician Canada
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 4/19/2005 3 Male 9/8/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious Male 9/18/2006 Physician Canada
Primary
Concomitant
Sepsis Life Threatening 4/19/2005 3 Male 9/20/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious Male 10/4/2006 Physician Canada
Primary
Concomitant
Transplant Failure Other Serious 58 Male 146 lb 10/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting 2/8/2006 36 Male Physician United States
Primary
Concomitant
Haematocrit Decreased Other Serious 10/20/2006 Male 217 lb 10/24/2006 Pharmacist United States
Primary
Concomitant
Transaminases Increased Life Threatening 7/26/2006 58 Male 186 lb 8/9/2006 Pharmacist United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2004 Male 146 lb 12/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 1/26/2005 41 Female 132 lb 12/4/2006 Other Health Professional Canada
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2004 Male 146 lb 1/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/1/2006 Male 1/22/2007 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 8/13/2006 56 Female 148 lb 1/18/2007 Pharmacist United States
Primary
Secondary
Concomitant
Transplant Failure Other Serious 1/31/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 5/1/2006 Male 146 lb 2/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Lesion Other Serious 0 Male 2/15/2007 Other Health Professional Turkey
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/13/2004 53 Male 163 lb 4/5/2007 Physician Canada
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 1/29/2007 52 Female 4/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Aplastic Anaemia Hospitalization 5/1/2006 59 Male 146 lb 12/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 5/7/2007 34 Female 5/29/2007 France
Primary
Concomitant
Venous Occlusion Hospitalization 59 Female 6/13/2007 Other Health Professional Germany
Primary
Secondary
Urinary Tract Infection Hospitalization 11/13/2004 53 Male 163 lb 4/5/2007 Physician Canada
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 1/29/2007 52 Female 7/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 43 Female 8/24/2007 France
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Hospitalization 5/7/2007 34 Female 10/23/2007 Physician France
Primary
Concomitant
Weight Increased Hospitalization 5/1/2005 16 Male 112 lb 12/1/2007 Other Health Professional Japan
Primary
Concomitant
Weight Increased Hospitalization 5/1/2005 16 Male 112 lb 12/29/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 10/5/2007 36 Male 1/16/2008 Netherlands
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 3/19/2004 44 Female 1/25/2008 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 9/1/2007 50 Female 82 lb 2/19/2008 Physician Japan
Primary
Concomitant
Transplant Failure Other Serious 3/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 9/1/2007 50 Female 82 lb 4/4/2008 Physician Japan
Primary
Concomitant
Nephrotic Syndrome Other Serious 5/1/2005 16 Male 112 lb 4/10/2008 Japan
Primary
Secondary
Concomitant
Haemorrhage Other Serious 6/28/2004 64 Male 4/29/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Sepsis Other Serious 9/1/2007 50 Female 82 lb 4/30/2008 Physician Japan
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 21 Male 6/24/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2007 Female 7/11/2008 Physician United Kingdom
Primary
Concomitant
Hypoxia Life Threatening 7/24/2007 62 Male 170 lb 7/30/2008 Pharmacist United States
Primary
Concomitant
Gingival Hyperplasia Hospitalization 7/20/2008 Male 8/7/2008 Physician United States
Primary
Secondary
Concomitant
Gingival Hyperplasia Hospitalization 7/20/2008 Male 8/21/2008 Physician United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 8/4/2005 15 Male 159 lb 9/26/2008 Physician United States
Primary
Concomitant
Sepsis Other Serious 55 Male 9/26/2008 Other Health Professional United States
Primary
Concomitant
Sepsis Other Serious 43 Male 9/26/2008 Other Health Professional United States
Primary
Concomitant
Sepsis Death 44 Male 9/26/2008 Other Health Professional United States
Primary
Concomitant
Sepsis Other Serious 45 Male 9/26/2008 Other Health Professional United States
Primary
Concomitant
Cytomegalovirus Infection Other Serious 30 Male 6/14/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 21 Male 6/14/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Mucous Membrane Disorder Other Serious Male 10/3/2008 Other Health Professional Japan
Primary
Concomitant
Platelet Count Decreased Other Serious Male 10/17/2008 Other Health Professional Japan
Primary
Concomitant
Impaired Gastric Emptying Hospitalization 10/7/2008 Male 11/12/2008 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 8/4/2005 15 Male 159 lb 11/18/2008 Physician United States
Primary
Concomitant
Gingival Hyperplasia 7/20/2008 Male 11/24/2008 Physician United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis 3/1/2008 Female 118 lb 12/12/2008 Consumer United States
Primary
Concomitant
Sepsis Other Serious 65 Male 12/18/2008
Primary
Secondary
Histiocytosis Haematophagic Other Serious 51 Female 12/23/2008
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 7/1/2008 54 Female 1/27/2009 Other Health Professional France
Primary
Secondary
Concomitant
Myocarditis Hospitalization 7/4/2008 54 Female 1/28/2009
Primary
Secondary
Concomitant
Pyrexia Other Serious 41 Female 2/6/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Encephalopathy Death 62 Male 2/6/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 10/5/2007 36 Male 2/13/2009 Netherlands
Primary
Concomitant
Renal Failure Hospitalization 8/4/2005 15 Male 159 lb 3/13/2009 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 1/9/2009 51 Male 174 lb 3/9/2009 Physician Canada
Primary
Concomitant
Vomiting Female 3/20/2009 Consumer United States
Primary
Concomitant
Type Iii Immune Complex Mediated Reaction Death 62 Male 3/19/2009 Physician Japan
Primary
Concomitant
Death Death 2/1/2004 Female 4/3/2009 Physician Israel
Primary
Secondary
Concomitant
Malabsorption Death 4/3/2009 4/21/2009 Canada
Primary
Concomitant
Staphylococcal Sepsis Other Serious 10/1/2008 5/1/2009 United States
Primary
Concomitant
Subdural Haematoma Hospitalization 7/11/2007 5/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
Application Site Discolouration 5/6/2009 1 Female 13 lb 5/6/2009 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Other Serious 10/1/2008 Male 161 lb 5/23/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 5/29/2009 Male 120 lb 6/10/2009 Physician United States
Primary
Concomitant
Subcutaneous Abscess Hospitalization 5/28/2009 Male 6/19/2009 Other Health Professional France
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 1/13/2004 Female 196 lb 6/23/2009 Physician Israel
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 5/20/2003 Male 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Ureteric Stenosis Other Serious 6/3/2004 Male 178 lb 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 8/23/2004 Male 189 lb 6/23/2009 Physician Israel
Primary
Secondary
Concomitant
Urinoma Hospitalization 11/13/2004 Male 163 lb 6/23/2009 Physician Canada
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/27/2004 Male 183 lb 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Sepsis Other Serious 8/4/2004 Male 132 lb 6/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Shock Haemorrhagic Other Serious 1/13/2004 Female 6/24/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 3/23/2005 Male 7/7/2009 Consumer Germany
Primary
Secondary
Concomitant
Liver Injury Other Serious 6/17/2009 0 Female 19 lb 7/7/2009 Pharmacist United States
Primary
Concomitant
No Adverse Event Other Serious 8/4/2004 65 Male 7/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/23/2004 Male 7/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vesicoureteric Reflux Other Serious 1/1/2005 48 Female 7/30/2009 Other Health Professional India
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 1/13/2004 50 Female 7/31/2009 Physician Israel
Primary
Secondary
Concomitant
Rash Other Serious 50 Male 9/4/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 48 Female 9/29/2009 Other Health Professional India
Primary
Secondary
White Blood Cell Count Increased Other Serious 5/29/2009 Male 120 lb 10/16/2009 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 8/18/2009 23 Male 11/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 9/16/2009 22 Male 169 lb 11/4/2009 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 9/16/2009 22 Male 169 lb 11/20/2009 Physician United States
Primary
Secondary
Concomitant
Transplant Failure Hospitalization Female 12/11/2009 Physician United States
Primary
Secondary
Concomitant
Treatment Failure Other Serious 1/1/2008 31 Male 12/3/2009 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 55 Female 12/3/2009 Physician Japan
Secondary
Concomitant
Transaminases Increased Other Serious 1/1/2008 31 Male 12/3/2009 Physician Japan
Secondary
Concomitant
Pain In Extremity Other Serious 11/27/2009 56 Female 200 lb 12/17/2009 Pharmacist United States
Primary
Concomitant
Shock Other Serious 9/16/2009 22 Male 169 lb 1/7/2010 Physician United States
Primary
Secondary
Concomitant
Angioedema Life Threatening 1/12/2010 16 Female 132 lb 1/20/2010 Physician Spain
Primary
Concomitant
Angioedema Life Threatening 1/12/2010 16 Female 132 lb 1/22/2010 Physician Spain
Primary
Concomitant
Oesophageal Candidiasis Hospitalization 12/16/2009 Male 129 lb 1/22/2010 Physician Italy
Primary
Secondary
Concomitant
Oesophageal Candidiasis Hospitalization 12/16/2009 Male 129 lb 2/12/2010 Physician Italy
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Death 63 Male 3/1/2010 Physician Spain
Primary
Concomitant
Malabsorption Death 4/3/2009 55 Male 4/2/2010 Canada
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 1/1/2008 50 Male 4/20/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Skin Tightness Other Serious 2/1/2008 55 Female 110 lb 6/1/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 4/10/2005 52 Female 110 lb 6/8/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 4/10/2005 42 Female 110 lb 7/14/2010 Lawyer United States
Primary
Secondary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 40 Female 8/17/2010 Physician United States
Primary
Concomitant
Rash Pustular Other Serious 40 Female 9/3/2010 Physician United States
Primary
Concomitant
Petechiae Other Serious 10/1/2009 71 Female 9/16/2010 Physician United States
Primary
Concomitant
Stomatitis Other Serious 1 Male 9/21/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 1 Male 9/21/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 9/16/2009 22 Male 169 lb 9/28/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 7 Female 9/30/2010 Physician Japan
Primary
Concomitant
Transplant Failure Hospitalization Female 273 lb 10/14/2010 Physician United States
Primary
Secondary
Concomitant
Leukaemia Recurrent Other Serious 3 Female 10/12/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 56 Female 10/29/2010 Physician Germany
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 1/1/2010 64 Male 11/2/2010 Other Health Professional France
Primary
Concomitant
Thrombocytopenia Other Serious 56 Female 11/4/2010 Other Health Professional France
Primary
Concomitant
Fungaemia Death 6/22/2005 46 Male 126 lb 11/15/2010 Physician Japan
Primary
Secondary
Concomitant
Recurrent Cancer Other Serious 56 Female 11/17/2010 Physician France
Primary
Concomitant
Oedema Other Serious 8/16/2009 7 Male 66 lb 12/10/2010 Physician Hungary
Primary
Secondary
Concomitant
Engraftment Syndrome Other Serious 8/23/2009 8 Female 71 lb 12/10/2010 Physician Hungary
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 8/23/2010 20 Female 104 lb 12/30/2010 Physician France
Primary
Concomitant
Aplasia Other Serious 12/21/2009 30 Female 119 lb 1/18/2011 Physician France
Primary
Concomitant
Pancreatitis Acute Other Serious 12/3/2010 46 Female 1/25/2011 Other Health Professional France
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 12/3/2010 46 Female 1/26/2011 Physician France
Primary
Secondary
Concomitant
Haematological Malignancy Death 2/7/2011 Physician France
Primary
Secondary
Concomitant
No Therapeutic Response Other Serious 1/1/2010 74 Male 2/8/2011 Other Health Professional United States
Primary
Concomitant
Pigmentation Disorder Hospitalization 1/8/2011 36 Female 2/8/2011 Other Health Professional France
Primary
Secondary
Concomitant
Neutropenia Other Serious 7 Female 2/7/2011 Physician Japan
Primary
Concomitant
Diarrhoea Hospitalization 9/23/2007 2/18/2011 Physician United States
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Other Serious 12/9/2010 2/22/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Transplant Failure Other Serious 11/12/2009 67 Female 273 lb 3/15/2011 Consumer United States
Primary
Secondary
Concomitant
Atrial Flutter Hospitalization 11/12/2009 67 Female 273 lb 3/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
No Therapeutic Response Hospitalization 1/1/2010 74 Male 133 lb 4/11/2011 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 4/15/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Septic Shock Death 4/15/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant

Drug Data