Cyclosporine combined with Fludarabine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Death 36 Female 1/5/2006 United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 47 Male 1/19/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Enterococcal 56 Female 3/9/2006 United States
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 1/1/2005 49 Female 4/11/2006 Japan
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 65 Male 4/12/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/26/2006 37 Male 181 lb 4/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 40 Male 5/5/2006 Other Health Professional Switzerland
Primary
Concomitant
Urinary Tract Infection Bacterial Other Serious 11/1/2005 61 Male 157 lb 5/3/2006 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 65 Male 6/2/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious Female 6/14/2006 Consumer Germany
Primary
Secondary
Concomitant
Pneumonia Aspergillus Other Serious Male 6/14/2006 Consumer Germany
Primary
Secondary
Concomitant
Pneumonia Aspergillus Other Serious Male 6/14/2006 Consumer Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2005 61 Male 157 lb 7/6/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Bacterial Other Serious 11/1/2005 61 Male 157 lb 7/6/2006 Physician United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 62 Male 7/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Superficial Spreading Melanoma Stage Ii Other Serious 59 Male 7/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 61 Male 7/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Neoplasm Excision Other Serious 53 Male 7/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Viral Infection Other Serious 1/1/2003 16 Female 7/28/2006 United Kingdom
Primary
Concomitant
Transplant Failure Hospitalization 9/9/2006 60 Male 191 lb 9/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Viral Dna Test Positive Other Serious 1/1/2006 64 Female 10/17/2006 Japan
Primary
Concomitant
Graft Versus Host Disease Other Serious 61 Female 10/19/2006
Primary
Secondary
Malignant Melanoma Other Serious 59 Male 10/19/2006
Primary
Secondary
Squamous Cell Carcinoma Other Serious 62 Male 10/19/2006
Primary
Secondary
Squamous Cell Carcinoma Other Serious 45 Male 10/19/2006
Primary
Secondary
Malignant Melanoma Other Serious 53 Male 10/19/2006
Primary
Secondary
Squamous Cell Carcinoma Other Serious 61 Male 10/19/2006
Primary
Secondary
Weight Increased Hospitalization 56 Female 12/9/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Mucous Stools Other Serious 4 Female 12/14/2006 Japan
Primary
Concomitant
Leukaemia Recurrent Other Serious 63 Male 1/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Death 25 Male 1/22/2007 Other Health Professional Spain
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious Female 1/23/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 1/30/2007 Japan
Primary
Concomitant
Vasculitis Death 15 Male 2/6/2007 Physician Canada
Primary
Secondary
Concomitant
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 2/8/2007 Japan
Primary
Concomitant
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 2/8/2007 Japan
Primary
Concomitant
Vasculitis Death 15 Male 2/12/2007 Physician Canada
Primary
Secondary
Concomitant
Renal Impairment Other Serious 56 Female 2/22/2007 Consumer Finland
Primary
Secondary
Concomitant
Leukaemia Recurrent Other Serious 63 Male 2/22/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 56 Female 2/23/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 1/1/1994 52 Female 3/1/2007
Primary
Secondary
Somnolence Other Serious 56 Female 3/2/2007
Primary
Secondary
White Blood Cell Count Decreased Other Serious 53 Female 3/8/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 15 Female 3/15/2007 Japan
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 56 Female 3/22/2007 United States
Primary
Concomitant
Interacting
Pleural Effusion Required Intervention 3/17/2007 28 Male 183 lb 3/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Analysis Abnormal Other Serious 53 Male 11/13/2007 Other Health Professional Portugal
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 53 Male 12/12/2007 Other Health Professional Portugal
Primary
Secondary
Stomatitis Other Serious 6 Male 12/23/2007 Japan
Primary
Concomitant
Weight Decreased Other Serious 25 Male 1/8/2008 Other Health Professional United Kingdom
Primary
Secondary
Lichenification Other Serious 61 Male 2/7/2008 Other Health Professional Sweden
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 1 Female 2/7/2008 Japan
Primary
Concomitant
Lichenification Other Serious 61 Male 2/7/2008 Other Health Professional Sweden
Primary
Concomitant
Graft Versus Host Disease Death 53 Male 2/18/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Death 15 Male 2/18/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 27 Female 2/18/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
No Therapeutic Response Death 33 Male 2/19/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Infection Death 2/19/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Death 15 Male 2/20/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 53 Male 2/20/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 27 Female 2/20/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Death 57 Male 2/20/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Infection Death 2/21/2008 Germany
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 2/21/2008 Germany
Primary
Secondary
Concomitant
Adenocarcinoma Death 2/21/2008 Canada
Primary
Secondary
Concomitant
Sepsis Other Serious 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Sepsis Other Serious 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Sepsis Other Serious 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Infection Other Serious 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Infection Other Serious 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Infection Other Serious 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Infection Death 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Infection Death 2/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Drug Toxicity Death 2/22/2008 France
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Death 2/22/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Infection Death 2/22/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Arrhythmia Death 2/22/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Death 2/22/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Encephalopathy Death 2/22/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 2/22/2008 Canada
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 2/22/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/22/2008 Other Health Professional United States
Primary
Secondary
Vaginal Inflammation Hospitalization 21 Female 2/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Inflammation Other Serious 12 2/25/2008 Other Health Professional United States
Primary
Concomitant
Multi-organ Failure Other Serious 7 Male 2/26/2008 United States
Primary
Secondary
Concomitant
Transplant Failure Death 2/28/2008 Netherlands
Primary
Secondary
Concomitant
Transplant Failure Death 2/28/2008 Netherlands
Primary
Secondary
Concomitant
Transplant Failure Death 2/28/2008 Netherlands
Primary
Secondary
Concomitant
Transplant Failure Death 2/28/2008 Netherlands
Primary
Secondary
Concomitant
Transplant Failure Death 2/28/2008 Netherlands
Primary
Secondary
Concomitant
Transplant Failure Death 2/28/2008 Netherlands
Primary
Secondary
Concomitant
Transplant Failure Death 2/28/2008 Netherlands
Primary
Secondary
Concomitant
Transplant Failure Death 2/28/2008 Netherlands
Primary
Secondary
Concomitant
Renal Disorder Other Serious 2/29/2008 Other Health Professional United States
Primary
Secondary
Oedema Mucosal Hospitalization 27 Female 3/12/2008 Japan
Primary
Secondary
Concomitant
Disease Progression Death 3/21/2008 United Kingdom
Primary
Secondary
Concomitant
Pneumonia Fungal Life Threatening 3/25/2008 India
Primary
Secondary
Concomitant
Pneumonia Fungal Life Threatening 3/26/2008 India
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious Male 3/27/2008 Other Health Professional Germany
Primary
Secondary
Viral Infection Other Serious 3/28/2008 France
Primary
Secondary
Concomitant
Drug Toxicity Death 3/28/2008 Russian Federation
Primary
Secondary
Concomitant
Pneumonitis Death 3/31/2008 Other Health Professional United States
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious Male 3/31/2008 Other Health Professional Germany
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death Male 4/2/2008 Germany
Primary
Secondary
Venoocclusive Liver Disease Other Serious 4/7/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Oedema Mucosal Hospitalization 27 Female 4/16/2008 Japan
Primary
Secondary
Concomitant
Human Herpesvirus 6 Infection Other Serious 11 Female 4/16/2008 Physician Austria
Primary
Secondary
Acute Graft Versus Host Disease Other Serious 21 Male 6/24/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 1 Male 7/25/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 39 Male 7/28/2008 Other Health Professional Germany
Primary
Secondary
Sepsis Death 73 Female 8/8/2008 Other Health Professional Turkey
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 59 Female 8/8/2008 Other Health Professional Italy
Primary
Concomitant
Vomiting Other Serious 31 Female 8/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Hospitalization 31 Female 8/13/2008 Consumer United States
Primary
Secondary
Concomitant
Neurotoxicity Death 8/15/2008 Other Health Professional Germany
Primary
Secondary
Stomatitis Other Serious 8/20/2008 Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious Male 8/20/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 31 Male 8/20/2008 Other Health Professional Brazil
Primary
Secondary
Stomatitis Other Serious 8/21/2008 Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 31 Female 8/21/2008 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 14 Male 8/22/2008 Other Health Professional Italy
Primary
Secondary
Venoocclusive Liver Disease Other Serious Male 8/22/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 8/28/2008 Other Health Professional France
Primary
Secondary
Vomiting Hospitalization 31 Female 8/28/2008 United Kingdom
Primary
Secondary
Concomitant
Systemic Mycosis Other Serious 5 Male 8/28/2008 Other Health Professional Israel
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 8/29/2008 Other Health Professional France
Primary
Secondary
Respiratory Distress Other Serious 9/2/2008 Other Health Professional Iran (Islamic Republic Of)
Primary
Secondary
Venoocclusive Disease Other Serious 9/2/2008 France
Primary
Secondary
Concomitant
Vomiting Hospitalization 31 Female 9/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Human Herpesvirus 6 Infection Other Serious 7/9/2002 11 Female 9/2/2008 Other Health Professional Austria
Primary
Secondary
Concomitant
Sepsis Other Serious 2/12/2008 Canada
Primary
Secondary
Concomitant
Tuberculosis Other Serious 32 Male 1/16/2009 Other Health Professional China
Primary
Secondary
Concomitant
Epstein-barr Virus Infection Other Serious 37 Male 1/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Factor Positive Other Serious 1/1/2005 36 Female 1/21/2009 Consumer United Kingdom
Primary
Secondary
Pneumonia Cytomegaloviral Other Serious 18 Male 1/27/2009 Other Health Professional India
Primary
Secondary
Concomitant
Pneumonia Fungal Death 23 Male 1/27/2009 Other Health Professional India
Primary
Secondary
Concomitant
Pneumonia Fungal Death 30 Male 1/27/2009 Other Health Professional India
Primary
Secondary
Concomitant
Pneumonia Fungal Death 15 Male 1/27/2009 Other Health Professional India
Primary
Secondary
Concomitant
Pneumonia Fungal Death 28 Male 1/27/2009 Other Health Professional India
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 16 Male 1/27/2009 Other Health Professional India
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 18 Male 1/27/2009 Other Health Professional India
Primary
Secondary
Concomitant
Myocarditis Hospitalization 7/4/2008 54 Female 1/28/2009
Primary
Secondary
Concomitant
Systemic Candida Death 39 Male 1/28/2009 Other Health Professional Japan
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 1/1/2006 49 Male 1/29/2009 Other Health Professional Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 42 Female 1/29/2009 Other Health Professional Japan
Primary
Concomitant
Pneumonia Bacterial Other Serious Female 1/29/2009 Other Health Professional Japan
Primary
Concomitant
Respiratory Failure Other Serious 3 Male 2/2/2009 Other Health Professional Japan
Primary
Secondary

Drug Data