Cyclosporine combined with Etoposide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Venoocclusive Liver Disease Hospitalization 11/19/2005 Female 83 lb 2/28/2006 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 11/19/2005 Female 83 lb 3/3/2006 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 11/19/2005 Female 83 lb 3/4/2006 Physician United States
Primary
Secondary
Concomitant
Thrombophlebitis Superficial Other Serious 55 Female 8/30/2006 Other Health Professional Denmark
Primary
Secondary
Thrombophlebitis Superficial Other Serious 55 Female 8/30/2006 Physician Denmark
Primary
Secondary
Thrombophlebitis Other Serious 55 Female 9/20/2006 Other Health Professional Denmark
Primary
Secondary
Opportunistic Infection Death 0 Female 10/25/2006 Physician Turkey
Primary
Secondary
Procedural Complication Death Female 10/27/2006 Turkey
Primary
Secondary
Tuberculosis Other Serious 6/1/1994 38 Male 11/15/2006 Other Health Professional Turkey
Primary
Secondary
Concomitant
Thrombophlebitis Required Intervention 1/1/2004 55 Female 12/6/2006 Other Health Professional Denmark
Primary
Concomitant
Procedural Complication Death 0 Female 12/20/2006 Turkey
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 2 Male 1/4/2007 Other Health Professional Thailand
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 8 Male 1/16/2007 Other Health Professional Germany
Primary
Concomitant
Lymphohistiocytosis Hospitalization 0 Female 3/1/2007 Physician United States
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 22 Female 4/18/2007 Other Health Professional Japan
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious Unknown 4/16/2007 Germany
Primary
Secondary
Spherocytic Anaemia Other Serious 41 Female 5/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Autoimmune Thrombocytopenia Other Serious 41 Female 5/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Tubular Disorder Death 7 Female 5/24/2007 Physician Italy
Primary
Secondary
Concomitant
Renal Tubular Disorder Other Serious 7 Female 5/30/2007 Physician Italy
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 13 Female 5/29/2007 Japan
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Death 13 Male 5/29/2007 Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 12 Male 5/29/2007 Japan
Primary
Secondary
Concomitant
Venoocclusive Disease Death 47 Male 5/20/2007 Physician Japan
Primary
Concomitant
Pain In Extremity Other Serious 13 Female 6/7/2007 Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 12 Male 6/7/2007 Japan
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Death 13 Male 6/7/2007 Japan
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 4/21/2007 0 Male 15 lb 5/17/2007 United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 46 Male 6/24/2007 Japan
Primary
Concomitant
Pseudomembranous Colitis Other Serious 11/17/2006 45 Male 6/25/2007 Japan
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 46 Male 7/6/2007 Japan
Primary
Concomitant
T-cell Lymphoma Hospitalization 39 Male 7/18/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Myeloid Leukaemia Other Serious 3 Female 8/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Renal Tubular Disorder Other Serious 7 Female 8/14/2007 Physician Italy
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious Female 8/10/2007 Physician United States
Primary
Secondary
Acute Myeloid Leukaemia Other Serious Female 8/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death 3 Female 8/29/2007 United Kingdom
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 4/21/2007 0 Male 15 lb 8/15/2007 United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 28 Male 10/17/2007
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 4/21/2007 0 Male 15 lb 10/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Myeloid Leukaemia Other Serious 3 Female 10/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Myeloid Leukaemia Other Serious 3 Female 10/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death Female 10/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Ureaplasma Infection Hospitalization 28 Male 10/11/2007 Switzerland
Primary
Secondary
Systemic Candida Other Serious 26 Male 11/8/2007 Other Health Professional Germany
Primary
Secondary
Ureaplasma Infection Other Serious 28 Male 11/5/2007 Switzerland
Primary
Secondary
Concomitant
Speech Disorder Developmental Other Serious Female 11/5/2007 Japan
Primary
Secondary
Venoocclusive Disease Life Threatening 9/19/2007 19 Female 11/19/2007 Consumer United Kingdom
Primary
Secondary
Dilatation Intrahepatic Duct Acquired Life Threatening 9/19/2007 19 Female 11/21/2007 United Kingdom
Primary
Secondary
Venoocclusive Disease Other Serious 9/19/2007 19 Female 11/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 8/1/2004 Male 11/21/2007 Other Health Professional United States
Primary
Secondary
Thrombotic Microangiopathy Death 2/26/2007 1 Female 11/16/2007 Japan
Primary
Concomitant
Ureaplasma Infection Other Serious 28 Male 11/23/2007 Physician Switzerland
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 9/19/2007 19 Female 11/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Disease Other Serious 9/19/2007 19 Female 11/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Dilatation Intrahepatic Duct Acquired Life Threatening 9/19/2007 19 Female 11/26/2007 United Kingdom
Primary
Secondary
Venoocclusive Disease Other Serious 19 Female 11/27/2007 Other Health Professional United Kingdom
Primary
Secondary
Systemic Candida Hospitalization 26 Male 11/15/2007 Germany
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 26 Male 11/21/2007 Germany
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 9/19/2007 12/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Life Threatening 9/19/2007 19 Female 11/26/2007 United Kingdom
Primary
Secondary
Parakeratosis Other Serious 8/1/2004 53 Male 11/20/2007 Consumer United States
Primary
Secondary
Venoocclusive Disease Other Serious 19 Female 11/30/2007 Pharmacist United Kingdom
Primary
Concomitant
Renal Tubular Necrosis Other Serious 53 Male 12/6/2007 Other Health Professional Portugal
Primary
Secondary
Lip And/or Oral Cavity Cancer Other Serious 53 Male 11/30/2007 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Disease Life Threatening 19 Female 12/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Venoocclusive Liver Disease Life Threatening 19 Female 11/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Renal Tubular Necrosis Other Serious 53 Male 12/12/2007 Other Health Professional Portugal
Primary
Secondary
Venoocclusive Disease Other Serious 9/19/2007 Female 137 lb 12/26/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 26 Male 12/19/2007 Germany
Primary
Secondary
Mucosal Inflammation Other Serious 4 Female 1/17/2008 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Other Serious 16 Male 1/17/2008 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Other Serious 10 Female 1/17/2008 Physician Germany
Primary
Secondary
Speech Rehabilitation Other Serious 1 Female 2/25/2008 Other Health Professional Japan
Primary
Concomitant
Encephalopathy Death 6 Male 2/29/2008 Other Health Professional United States
Primary
Secondary
Encephalopathy Death 6 Male 3/8/2008 United States
Primary
Concomitant
Vomiting Other Serious 6 Male 3/15/2008 Physician United States
Primary
Secondary
Concomitant
Viral Diarrhoea Death 6 Male 3/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Axonal Neuropathy Other Serious 2 Female 3/27/2008 Other Health Professional Japan
Primary
Secondary
Axonal Neuropathy Other Serious 2 Female 3/27/2008 Other Health Professional Japan
Primary
Secondary
Serum Ferritin Increased Hospitalization 2 Female 3/29/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 4 Female 4/3/2008 Japan
Primary
Secondary
Concomitant
Quadriplegia Hospitalization 2 Female 3/29/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 1/1/2008 6 Male 4/11/2008 Other Health Professional United States
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 5 Male 4/14/2008 Other Health Professional Germany
Primary
Secondary
Graft Versus Host Disease Other Serious 8 Male 4/14/2008 Other Health Professional Germany
Primary
Secondary
Herpes Zoster Other Serious 11 Male 4/14/2008 Other Health Professional Germany
Primary
Secondary
Neutropenia Other Serious 11 Male 4/14/2008 Other Health Professional Germany
Primary
Secondary
Graft Versus Host Disease Other Serious 15 Female 4/15/2008 Other Health Professional Germany
Primary
Secondary
Malignant Neoplasm Progression Other Serious 11 Female 4/15/2008 Other Health Professional Germany
Primary
Secondary
Venoocclusive Disease Life Threatening 19 Female 12/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Subdural Effusion Other Serious 6 Male 4/16/2008 Consumer United States
Primary
Secondary
Graft Versus Host Disease Other Serious 1/1/2008 6 Male 4/21/2008 Other Health Professional United States
Primary
Secondary
Graft Versus Host Disease Other Serious 1/1/2008 6 Male 4/22/2008 Consumer Japan
Primary
Secondary
Graft Versus Host Disease Other Serious 14 Female 4/23/2008 Germany
Primary
Concomitant
Graft Versus Host Disease Hospitalization 15 Female 4/24/2008 Germany
Primary
Concomitant
Toxoplasmosis Hospitalization 8 Male 4/24/2008 Germany
Primary
Concomitant
Graft Versus Host Disease Other Serious 14 Female 5/5/2008 Germany
Primary
Concomitant
Mucosal Inflammation 11/9/2007 1 Male 4/30/2008 Japan
Primary
Secondary
Concomitant
Zygomycosis Other Serious 1 Male 5/6/2008 Physician United States
Primary
Secondary
Zygomycosis Hospitalization 1 Male 5/7/2008 Physician United States
Primary
Secondary
Pancytopenia Hospitalization 2 Male 5/19/2008 Other Health Professional Czech Republic
Primary
Secondary
Thrombotic Thrombocytopenic Purpura Other Serious 5/20/2008 United Kingdom
Primary
Concomitant
Axonal Neuropathy Life Threatening 2 Female 5/21/2008
Primary
Secondary
Thrombotic Thrombocytopenic Purpura Other Serious 5/22/2008 United Kingdom
Primary
Concomitant
Zygomycosis Hospitalization 1 Male 6/17/2008
Primary
Secondary
Concomitant
Malignant Histiocytosis Other Serious 1 Male 6/20/2008 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Lymphoproliferative Disorder Death 17 6/30/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Lymphadenopathy Death 1/1/2007 71 Male 7/7/2008 Other Health Professional Japan
Primary
Concomitant
Vomiting Life Threatening 2/6/2008 1 Female 7/2/2008 Japan
Primary
Concomitant
Pyrexia Other Serious 1/1/2007 71 Male 7/10/2008 Other Health Professional Japan
Primary
Concomitant
Polyneuropathy Hospitalization 2 Female 7/3/2008 Japan
Primary
Secondary
Concomitant
T-cell Lymphoma Recurrent Other Serious 1/1/2006 39 Male 7/25/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Guillain-barre Syndrome Other Serious 37 Female 8/5/2008 Other Health Professional United States
Primary
Secondary
Pancytopenia Life Threatening 1/31/2008 Male 8/6/2008 Physician Japan
Primary
Concomitant
Zygomycosis Other Serious 0 Male 8/12/2008 Other Health Professional United States
Primary
Concomitant
Jaundice Other Serious 1 Female 8/27/2008 Physician Japan
Primary
Concomitant
Urticaria Other Serious 8/8/2008 Female 8/27/2008 Physician United States
Primary
Concomitant
Human Herpesvirus 6 Infection Other Serious 7/9/2002 11 Female 9/2/2008 Other Health Professional Austria
Primary
Secondary
Concomitant
Jaundice Other Serious 1 Female 9/4/2008 Physician Japan
Primary
Concomitant
Neutropenia Other Serious 7 Female 9/25/2008 Other Health Professional Austria
Primary
Secondary
Concomitant
Fungal Rhinitis Other Serious 41 Male 7/8/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Jaundice Other Serious 1 Female 10/3/2008 Physician Japan
Primary
Concomitant
Pancytopenia Other Serious 0 Female 10/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 7 Female 10/6/2008 Other Health Professional Austria
Primary
Secondary
Concomitant
Urticaria Other Serious 8/8/2008 Female 10/14/2008 Physician United States
Primary
Concomitant
Epstein-barr Virus Infection Hospitalization 61 Female 10/10/2008 United Kingdom
Primary
Secondary
Vomiting Death 8/30/2006 46 Male 10/13/2008 Japan
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 1 Male 10/16/2008
Primary
Secondary
Thrombotic Microangiopathy Other Serious 23 Male 10/17/2008 Other Health Professional Japan
Primary
Secondary
Zygomycosis Required Intervention 1 Male 10/20/2008 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Death 8/30/2006 46 Male 10/20/2008 Japan
Primary
Concomitant
Epstein-barr Virus Infection Hospitalization 61 Female 10/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Epstein-barr Virus Infection Other Serious 61 Female 10/29/2008 United Kingdom
Primary
Secondary
Pyrexia Hospitalization 61 Female 11/4/2008 United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 66 Male 11/10/2008 Other Health Professional Germany
Primary
Concomitant
Epstein-barr Virus Infection Hospitalization 61 Female 11/4/2008 United Kingdom
Primary
Secondary
Hypertension Other Serious 0 11/13/2008 Other Health Professional United Kingdom
Primary
Secondary
Hypertension Other Serious 0 11/14/2008 United Kingdom
Primary
Secondary
Hypertension Other Serious 0 11/19/2008 Other Health Professional United Kingdom
Primary
Secondary
No Adverse Event 0 11/24/2008 United Kingdom
Primary
Secondary
Toxic Encephalopathy Other Serious 3/1/2006 13 Female 11/24/2008 Other Health Professional Japan
Primary
Concomitant
Pancytopenia Hospitalization 2 Female 4/6/2008 Japan
Primary
Secondary
Concomitant
Hypertension Other Serious 0 11/25/2008 United Kingdom
Primary
Secondary
Hypertension Other Serious 0 11/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Pyrexia Other Serious 61 Female 12/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Pyrexia Hospitalization 61 Female 12/22/2008 Consumer United Kingdom
Primary
Secondary
Pyrexia Other Serious 61 Female 12/23/2008 United Kingdom
Primary
Secondary
Inappropriate Antidiuretic Hormone Secretion Other Serious 14 Female 1/5/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Ineffective Other Serious Male 1/6/2009 Physician Sweden
Primary
Concomitant

Drug Data