Cyclosporine combined with Cytarabine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tachycardia Death 1/28/2006 Female 194 lb 2/24/2006 United States
Primary
Secondary
Viraemia Other Serious 28 Male 3/10/2006 Japan
Primary
Concomitant
Trichosporon Infection Other Serious 1/1/2004 30 Male 3/9/2006 Japan
Primary
Concomitant
Transplant Rejection Other Serious 1 Male 3/15/2006 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 20 Male 4/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Hospitalization 5/22/2006 Male 204 lb 6/2/2006 United States
Primary
Secondary
Skin Hyperpigmentation Hospitalization 6/5/2006 Male 234 lb 6/7/2006 United States
Primary
Secondary
Tri-iodothyronine Free Increased Other Serious 42 Male 6/16/2006 Physician Japan
Primary
Concomitant
Thyroxine Free Increased Other Serious 32 Female 6/16/2006 Other Health Professional Japan
Primary
Concomitant
Pyrexia Hospitalization 6/6/2006 Male 198 lb 6/12/2006 United States
Primary
Secondary
Renal Impairment Other Serious 35 Male 9/5/2006 Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 35 Male 9/5/2006 Physician Japan
Primary
Secondary
Concomitant
Viraemia Other Serious 28 Male 9/23/2006 Japan
Primary
Concomitant
Viral Infection Other Serious 45 Female 9/20/2006 Physician Germany
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 8/27/2006 Male 231 lb 9/21/2006 United States
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Hospitalization 9/25/2006 Male 207 lb 9/26/2006 United States
Primary
Secondary
Viraemia Other Serious 28 Male 10/2/2006 Japan
Primary
Concomitant
Pneumomediastinum Other Serious 35 Male 10/11/2006
Primary
Secondary
Pancreatitis Other Serious 10/20/2006 17 Female 112 lb 12/18/2006 United Kingdom
Primary
Secondary
Concomitant
Leukaemia Recurrent Other Serious 63 Male 1/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 1/30/2007 Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/14/2007 Male 207 lb 1/18/2007 United States
Primary
Secondary
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 2/8/2007 Japan
Primary
Concomitant
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 2/8/2007 Japan
Primary
Concomitant
Leukaemia Recurrent Other Serious 63 Male 2/22/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 1/1/1994 52 Female 3/1/2007
Primary
Secondary
Somnolence Other Serious 56 Female 3/2/2007
Primary
Secondary
Somnolence Other Serious 13 Male 3/3/2007 Japan
Primary
Secondary
Somnolence Other Serious 13 Male 3/14/2007 Japan
Primary
Secondary
Somnolence Other Serious 16 Male 3/15/2007 Japan
Primary
Secondary
Somnolence Other Serious 3 Male 3/15/2007 Japan
Primary
Secondary
Leukaemia Recurrent Death 63 Male 4/4/2007 France
Primary
Secondary
Concomitant
Tremor Hospitalization 1/29/2007 Male 227 lb 4/12/2007 United States
Primary
Secondary
Spherocytic Anaemia Other Serious 41 Female 5/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Autoimmune Thrombocytopenia Other Serious 41 Female 5/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/1/2003 31 Male 6/23/2007 Japan
Primary
Concomitant
Viral Dna Test Positive Other Serious 38 Male 6/26/2007 Japan
Primary
Secondary
Concomitant
Pseudomembranous Colitis Other Serious 11/17/2006 45 Male 6/25/2007 Japan
Primary
Secondary
Concomitant
Myeloid Leukaemia Other Serious 3 Female 8/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Other Serious Female 8/10/2007 Physician United States
Primary
Secondary
Acute Myeloid Leukaemia Other Serious Female 8/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death 3 Female 8/29/2007 United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 8/1/2007 8 Male 88 lb 9/11/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Somnolence Other Serious 8/1/2007 8 Male 88 lb 10/12/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 28 Male 10/17/2007
Primary
Secondary
Concomitant
Myeloid Leukaemia Other Serious 3 Female 10/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Myeloid Leukaemia Other Serious 3 Female 10/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Death Female 10/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Somnolence Other Serious 1/1/2007 8 Male 88 lb 10/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 1/1/2007 8 Male 88 lb 10/31/2007 Physician United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 1/1/2004 Male 11/8/2007 Other Health Professional Portugal
Primary
Secondary
Concomitant
Systemic Candida Other Serious 26 Male 11/8/2007 Other Health Professional Germany
Primary
Secondary
Somnolence Other Serious 8/1/2007 8 Male 88 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Ureaplasma Infection Other Serious 28 Male 11/5/2007 Switzerland
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 8/18/2007 8 Male 88 lb 11/12/2007 Physician United States
Primary
Secondary
Concomitant
Hepatotoxicity Life Threatening 24 Male 11/15/2007 Physician Germany
Primary
Secondary
Concomitant
Ureaplasma Infection Other Serious 28 Male 11/23/2007 Physician Switzerland
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 26 Male 11/15/2007 Germany
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 26 Male 11/21/2007 Germany
Primary
Secondary
Concomitant
Parakeratosis Other Serious 8/1/2004 53 Male 11/20/2007 Consumer United States
Primary
Secondary
Renal Tubular Necrosis Other Serious 53 Male 12/6/2007 Other Health Professional Portugal
Primary
Secondary
Lip And/or Oral Cavity Cancer Other Serious 53 Male 11/30/2007 Physician United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 2/1/2001 52 Male 12/10/2007 Japan
Primary
Concomitant
Renal Transplant Other Serious 11/1/2005 22 Female 12/10/2007 Japan
Primary
Concomitant
Renal Tubular Necrosis Other Serious 53 Male 12/12/2007 Other Health Professional Portugal
Primary
Secondary
Stress Other Serious 28 Male 12/14/2007 Australia
Primary
Secondary
Systemic Candida Hospitalization 26 Male 12/19/2007 Germany
Primary
Secondary
Toxoplasma Serology Positive Other Serious 2/1/2007 56 Female 12/28/2007 Other Health Professional Germany
Primary
Concomitant
Subcutaneous Emphysema Other Serious 17 Male 1/19/2008 Other Health Professional Japan
Primary
Concomitant
Drug Toxicity Death 2/22/2008 France
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 7 Male 2/26/2008 United States
Primary
Secondary
Concomitant
Nocardiosis Other Serious 17 Male 3/12/2008 Other Health Professional Japan
Primary
Secondary
Venoocclusive Disease Other Serious 3/13/2008 Physician Germany
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 17 Male 3/19/2008 Physician India
Primary
Secondary
Reticulocyte Count Increased Hospitalization 33 Male 3/26/2008 United States
Primary
Secondary
Concomitant
Nocardiosis Other Serious 17 Male 3/27/2008 Other Health Professional Japan
Primary
Secondary
Pneumonia Bacterial Other Serious 4/9/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 4/9/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 4/9/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 5/20/2008 United Kingdom
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 5/22/2008 United Kingdom
Primary
Concomitant
Streptococcal Sepsis Other Serious 6/5/2008 Germany
Primary
Secondary
Concomitant
Streptococcal Sepsis Other Serious 6/9/2008 Germany
Primary
Secondary
Concomitant
Herpes Simplex Other Serious 18 Female 6/18/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/22/2007 64 Male 6/30/2008 Physician Japan
Primary
Concomitant
Enterobacter Sepsis Hospitalization 8/21/2007 29 Male 7/8/2008 Japan
Primary
Concomitant
Tuberculosis Other Serious 31 Female 7/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Guillain-barre Syndrome Other Serious 37 Female 8/5/2008 Other Health Professional United States
Primary
Secondary
Malignant Neoplasm Progression Other Serious 17 Male 8/5/2008 Other Health Professional United States
Primary
Secondary
Parainfluenzae Virus Infection Other Serious 16 Male 8/5/2008 Other Health Professional United States
Primary
Secondary
Multi-organ Failure Other Serious 18 Male 8/5/2008 Other Health Professional United States
Primary
Secondary
Pancytopenia Life Threatening 1/31/2008 Male 8/6/2008 Physician Japan
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 8/6/2008 China
Primary
Concomitant
Tremor Other Serious 8/6/2008 China
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 8/6/2008 China
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 8/6/2008 China
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 8/6/2008 China
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 8/6/2008 China
Primary
Concomitant
Therapeutic Agent Toxicity Death 8/6/2008 China
Primary
Concomitant
Vomiting Other Serious 31 Female 8/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Hospitalization 31 Female 8/13/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 31 Female 8/21/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 31 Female 8/28/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 31 Female 9/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stomatitis Death 1/15/2008 47 Male 9/15/2008 Japan
Primary
Concomitant
Stomatitis Life Threatening 9/6/2007 59 Male 9/19/2008 Japan
Primary
Concomitant
Fungal Rhinitis Other Serious 41 Male 7/8/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 44 Female 9/29/2008 Japan
Primary
Secondary
Thrombotic Microangiopathy Other Serious 44 Female 10/7/2008 Japan
Primary
Secondary
Immune Reconstitution Syndrome Hospitalization 31 Female 10/14/2008 Consumer United States
Primary
Secondary
Concomitant
Epstein-barr Virus Infection Hospitalization 61 Female 10/10/2008 United Kingdom
Primary
Secondary
Pyrexia Death 21 Female 10/14/2008 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Stomatitis Death 5/30/2007 41 Female 10/13/2008 Japan
Primary
Concomitant
Platelet Count Decreased Other Serious Male 10/17/2008 Other Health Professional Japan
Primary
Concomitant
Epstein-barr Virus Infection Hospitalization 61 Female 10/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Epstein-barr Virus Infection Other Serious 61 Female 10/29/2008 United Kingdom
Primary
Secondary
Pyrexia Hospitalization 61 Female 11/4/2008 United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 66 Male 11/10/2008 Other Health Professional Germany
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 34 Male 11/8/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Epstein-barr Virus Infection Hospitalization 61 Female 11/4/2008 United Kingdom
Primary
Secondary
Drug Toxicity Death 11/17/2008 France
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 5 Male 11/25/2008 Other Health Professional Israel
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 3/1/2006 13 Female 11/24/2008 Other Health Professional Japan
Primary
Concomitant
Pneumonia Fungal Other Serious 11/26/2008 Other Health Professional United States
Primary
Concomitant
Pneumonitis Other Serious 11/26/2008 Other Health Professional United States
Primary
Concomitant
Pyrexia Other Serious 61 Female 12/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Tumour Lysis Syndrome Death 18 Female 12/16/2008 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 61 Female 12/22/2008 Consumer United Kingdom
Primary
Secondary
Pseudomembranous Colitis Other Serious 43 Male 12/22/2008 Other Health Professional Japan
Primary
Secondary
Pyrexia Other Serious 61 Female 12/23/2008 United Kingdom
Primary
Secondary
Tumour Lysis Syndrome Other Serious 1/1/2003 18 Female 1/12/2009
Primary
Secondary
Vomiting Death 24 Male 1/22/2009 Japan
Primary
Concomitant
Hepatic Steatosis Other Serious 14 Male 1/29/2009 Other Health Professional Japan
Primary
Secondary
Stomatitis Hospitalization 5/30/2007 41 Female 1/27/2009 Japan
Primary
Concomitant
Residual Urine Other Serious 25 Male 2/3/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 9/1/2008 21 Male 146 lb 3/20/2009 Physician Japan
Primary
Secondary
Concomitant
Viral Haemorrhagic Cystitis Other Serious 6/27/2008 44 Male 148 lb 3/20/2009 Physician Japan
Primary
Concomitant
Swollen Tongue Other Serious 16 Male 3/26/2009 Other Health Professional Japan
Primary
Concomitant
Stem Cell Transplant Other Serious 10/10/2007 59 Female 3/26/2009 Other Health Professional France
Primary
Concomitant
Stridor Hospitalization 17 4/3/2009 Other Health Professional Japan
Primary
Concomitant
Swollen Tongue Other Serious 16 Male 4/3/2009 Other Health Professional Japan
Primary
Concomitant
Swollen Tongue Other Serious 16 Male 4/3/2009 Other Health Professional Japan
Primary
Concomitant
Sepsis Life Threatening 6/27/2008 36 Female 97 lb 4/9/2009 Physician Japan
Primary
Concomitant
Graft Versus Host Disease Other Serious 17 Male 4/15/2009 Other Health Professional India
Primary
Secondary
Concomitant
Neurofibroma Hospitalization 17 Female 4/23/2009 Other Health Professional Japan
Primary
Secondary
Septic Shock Other Serious 16 5/8/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 54 Male 5/18/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Syncope Hospitalization 1/23/2009 14 Female 5/28/2009 Netherlands
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 36 Male 6/16/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 4 6/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data