Cyclophosphamide combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tooth Loss Other Serious 4/1/2005 68 Female 1/4/2006 Physician Italy
Primary
Concomitant
Radiation Injury Other Serious 63 Female 132 lb 1/12/2006 Physician United Kingdom
Primary
Concomitant
Renal Failure Other Serious 63 Female 132 lb 1/17/2006 Physician United Kingdom
Primary
Concomitant
Pain In Jaw Other Serious 12/7/2004 66 Male 1/21/2006 United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 2/1/2005 67 Male 179 lb 2/2/2006 United Kingdom
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2005 Female 2/2/2006 Physician Germany
Primary
Concomitant
Surgery Other Serious 6/27/2005 Female 2/18/2006 Spain
Primary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 2/24/2006 United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Life Threatening 10/10/2005 70 Male 181 lb 2/17/2006 Physician France
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 52 Male 3/15/2006 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 52 Male 3/24/2006 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 4/10/2006 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 11/28/2003 64 Male 197 lb 4/28/2006 United Kingdom
Primary
Secondary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 5/5/2006 United States
Primary
Secondary
Concomitant
Toothache Other Serious 63 Female 132 lb 5/24/2006 Portugal
Primary
Concomitant
Swelling Other Serious 4/13/2006 51 Female 5/24/2006 Physician Portugal
Primary
Concomitant
Wound Drainage Other Serious 1/1/2001 52 Male 5/31/2006 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 5/31/2006 United States
Primary
Secondary
Concomitant
Toothache Other Serious 8/1/2005 63 Female 132 lb 6/8/2006 Portugal
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2005 Female 6/16/2006 Other Health Professional Turkey
Primary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 6/20/2006 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 1/1/2003 61 Male 187 lb 7/21/2006 Physician Germany
Primary
Concomitant
Renal Failure Life Threatening 8/19/2004 47 Female 7/25/2006 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 68 Male 8/17/2006 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Other Serious 64 Male 8/17/2006 Other Health Professional United States
Primary
Concomitant
Prosthesis Implantation Other Serious 1/17/2006 61 Female 9/18/2006 Physician Belgium
Primary
Concomitant
Osteonecrosis Other Serious 2/1/2006 50 Female 9/18/2006 Physician Belgium
Primary
Concomitant
Soft Tissue Infection Disability 7/1/2006 49 Female 9/21/2006 Physician Australia
Primary
Concomitant
Osteonecrosis Hospitalization 5/5/2005 61 Female 10/3/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Neutrophil Count Decreased Death 8/21/2006 64 Female 125 lb 10/4/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 8/21/2006 64 Female 10/13/2006 Consumer United States
Primary
Secondary
Concomitant
Toothache Other Serious 10/1/2004 62 Male 10/18/2006 Physician Belgium
Primary
Concomitant
Tooth Abscess Other Serious 9/1/2005 60 Female 10/19/2006 Physician United Kingdom
Primary
Concomitant
Pleuritic Pain Hospitalization 8/19/2006 61 Female 161 lb 10/19/2006 Physician United States
Primary
Secondary
Concomitant
Pleuritic Pain Hospitalization 8/19/2006 61 Female 161 lb 10/25/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/18/2006 75 Female 12/5/2006 Physician Spain
Primary
Concomitant
Wound Debridement Other Serious 1/1/2005 70 Male 12/7/2006 Physician Belgium
Primary
Secondary
Concomitant
Wound Debridement Other Serious 2/1/2005 74 Female 12/7/2006 Physician Belgium
Primary
Concomitant
Osteonecrosis Other Serious 9/12/2005 67 Male 179 lb 12/8/2006 Consumer United Kingdom
Primary
Concomitant
Tooth Extraction Other Serious 10/1/2005 52 Male 119 lb 12/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tooth Extraction Other Serious 2/1/2005 64 Female 84 lb 12/12/2006 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/2005 64 Female 84 lb 12/14/2006 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious Male 12/21/2006 Physician Australia
Primary
Concomitant
Tooth Extraction Other Serious 2/1/2005 64 Female 84 lb 12/22/2006 Physician Japan
Primary
Secondary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 200 lb 1/18/2007 United States
Primary
Secondary
Concomitant
Uterine Neoplasm Hospitalization 12/1/2006 72 Female 115 lb 2/15/2007 Physician Japan
Primary
Concomitant
Pain In Jaw Other Serious 11/1/2006 64 Male 2/23/2007 Physician Australia
Primary
Concomitant
Tooth Disorder Other Serious 1/18/2006 75 Female 2/27/2007 Physician Spain
Primary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 200 lb 3/10/2007 United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Death 8/21/2006 64 Female 125 lb 3/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Surgery Other Serious 1/1/2001 66 Male 4/6/2007 Physician United States
Primary
Concomitant
Swelling Other Serious 12/1/2004 60 Male 210 lb 7/14/2007 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 3/23/2004 53 Female 8/18/2007 Physician Belgium
Primary
Concomitant
Tooth Extraction Other Serious 3/23/2004 53 Female 8/18/2007 Physician Belgium
Primary
Concomitant
Toothache Other Serious 5/1/2006 65 Female 9/18/2007 Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2004 60 Female 11/17/2007 Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2004 60 Female 11/20/2007 Japan
Primary
Secondary
Concomitant
Impaired Healing Hospitalization 8/10/2007 50 Female 128 lb 11/29/2007 Physician Germany
Primary
Secondary
Concomitant
Pain In Jaw Hospitalization 1/10/2007 68 Female 12/12/2007 France
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2004 60 Female 12/19/2007 Japan
Primary
Secondary
Concomitant
Spondylitis Other Serious 31 Female 1/25/2008 Consumer United States
Primary
Secondary
Concomitant
Spondylitis Other Serious 31 Female 1/31/2008 Consumer United States
Primary
Secondary
Concomitant
Spondylitis Other Serious 31 Female 2/7/2008 Consumer United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 5/18/2005 55 Female 176 lb 3/4/2008 Physician Denmark
Primary
Concomitant
Tooth Extraction Other Serious 7/5/2007 60 Female 165 lb 3/11/2008 Denmark
Primary
Concomitant
Osteonecrosis Other Serious 6/9/2007 66 Female 126 lb 3/17/2008 Physician Denmark
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/9/2007 66 Female 126 lb 3/18/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 5/20/2007 81 Female 4/11/2008 Other Health Professional Italy
Primary
Concomitant
Osteonecrosis Other Serious 1/1/2007 Female 4/24/2008 Physician Germany
Primary
Concomitant
Swelling Other Serious 6/9/2007 Female 126 lb 5/20/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 6/11/2007 62 Female 5/22/2008 Consumer United States
Primary
Secondary
Concomitant
Swelling Other Serious 6/9/2007 Female 126 lb 5/29/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Swelling Other Serious 8/2/2001 Male 200 lb 7/14/2008 United States
Primary
Secondary
Concomitant
Swelling Other Serious 8/2/2001 Male 200 lb 7/14/2008 United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 5/1/2008 Male 7/15/2008 Physician Switzerland
Primary
Concomitant
Feeling Abnormal 12/26/2006 7/22/2008 Other Health Professional United States
Primary
Concomitant
Swelling Other Serious 8/2/2001 Male 200 lb 7/31/2008 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/9/2007 Female 126 lb 7/31/2008 Physician Denmark
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 8/29/2006 Female 8/8/2008 Physician United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 8/21/2006 64 Female 125 lb 8/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swelling Other Serious 6/9/2007 Female 126 lb 8/22/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pneumonia Other Serious 5/1/2008 Male 8/25/2008 Physician Switzerland
Primary
Concomitant
Osteonecrosis Other Serious 5/1/2008 Female 9/17/2008 Physician Germany
Primary
Secondary
Leukopenia Other Serious 10/30/2008 56 Female 207 lb 12/1/2008 Physician Germany
Primary
Secondary
Concomitant
Leukopenia Other Serious 10/30/2008 56 Female 207 lb 12/23/2008 Physician Germany
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 Male 150 lb 1/13/2009 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 5/23/2008 Female 95 lb 3/18/2009 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Life Threatening 11/21/2008 46 Female 90 lb 3/20/2009 Other Health Professional Japan
Primary
Concomitant
Swelling Other Serious 8/1/2008 Female 110 lb 4/2/2009 Physician Japan
Primary
Concomitant
Primary Sequestrum Other Serious 6/1/2007 71 Female 4/2/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Swelling Other Serious 8/1/2008 Female 110 lb 4/14/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 5/23/2008 Female 95 lb 4/17/2009 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 9/17/2008 Female 132 lb 4/20/2009 Physician Japan
Primary
Secondary
Concomitant
Temporal Arteritis Hospitalization 3/1/2009 Female 5/7/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 12/12/2001 Male 5/13/2009 Lawyer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 4/1/2009 Female 117 lb 6/16/2009 Physician Japan
Primary
Concomitant
Osteonecrosis Other Serious 2/9/2009 51 Male 121 lb 6/29/2009 Other Health Professional Spain
Primary
Secondary
Toothache Other Serious 3/1/2008 Female 126 lb 7/7/2009 Other Health Professional Japan
Primary
Concomitant
Tooth Extraction Other Serious 11/1/2007 76 Female 7/10/2009 Other Health Professional Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 4/1/2009 Female 117 lb 7/30/2009 Physician Japan
Primary
Concomitant
Leukopenia Life Threatening 10/30/2008 56 Female 207 lb 8/21/2009 Physician Germany
Primary
Secondary
Concomitant
Osteomyelitis Other Serious 8/12/2009 Female 9/15/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Leukopenia Other Serious 10/30/2008 56 Female 207 lb 9/10/2009 Physician Germany
Primary
Secondary
Concomitant
Toothache Other Serious 3/1/2008 Female 126 lb 9/17/2009 Other Health Professional Japan
Primary
Concomitant
Osteomyelitis Other Serious 8/12/2009 Female 9/29/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 7/13/2009 Female 130 lb 9/29/2009 Physician Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 4/1/2009 Female 117 lb 10/7/2009 Other Health Professional Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 4/1/2009 Female 117 lb 10/14/2009 Japan
Primary
Concomitant
Osteonecrosis Other Serious 7/27/2009 Female 10/22/2009 Physician Romania
Primary
Concomitant
Osteonecrosis Disability 1/1/2005 Female 12/2/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Osteonecrosis Disability 1/1/2005 Female 12/24/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Osteonecrosis Disability 1/1/2004 Female 12/28/2009 Other Health Professional Italy
Primary
Concomitant
Sequestrectomy Other Serious 12/1/2006 Male 12/31/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Sensory Disturbance Other Serious 6/29/2007 Female 126 lb 1/4/2010 Denmark
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/1/2005 Male 136 lb 1/15/2010 Physician United States
Primary
Concomitant
Osteonecrosis Disability 1/1/2004 Female 1/22/2010 Other Health Professional Italy
Primary
Concomitant
Sequestrectomy Other Serious 12/1/2006 Male 2/1/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 12/12/2001 Male 2/5/2010 Physician United States
Primary
Secondary
Concomitant
Peptostreptococcus Infection Other Serious 9/1/2009 Female 2/8/2010 Other Health Professional Denmark
Primary
Concomitant
Weight Decreased Other Serious 4/9/2002 Male 136 lb 2/15/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 5/12/2005 Male 136 lb 2/24/2010 Physician United States
Primary
Concomitant
Venous Thrombosis Other Serious 12/12/2001 Male 2/26/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/12/2005 Male 136 lb 3/2/2010 Physician United States
Primary
Concomitant
Walking Aid User Other Serious 8/11/2008 Male 219 lb 3/5/2010 United States
Primary
Secondary
Concomitant
Periodontal Infection Other Serious 3/11/2010 54 Male 165 lb 3/11/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 5/12/2005 Male 136 lb 3/18/2010 Physician United States
Primary
Concomitant
Walking Aid User Other Serious 5/1/2007 Male 219 lb 3/19/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/14/1999 Male 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 Female 3/23/2010 Other Health Professional United States
Primary
Concomitant
Tooth Infection Other Serious 1/7/2010 Male 3/24/2010 Other Health Professional France
Primary
Concomitant
X-ray Abnormal Other Serious 12/29/2000 Female 148 lb 3/25/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/14/1999 Male 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/12/2005 Male 136 lb 3/30/2010 Physician United States
Primary
Concomitant
Walking Aid User Other Serious 5/1/2007 Male 219 lb 3/31/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2001 50 Female 4/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Prostate Cancer Stage Iv Death Male 4/8/2010 Japan
Primary
Concomitant
Weight Decreased Other Serious 3/14/1999 48 Male 4/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 8/4/2009 61 Female 134 lb 4/8/2010 Pharmacist Japan
Primary
Concomitant
Weight Decreased Other Serious 5/12/2005 60 Male 136 lb 4/9/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Other Serious 5/1/2007 68 Male 219 lb 4/15/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/14/1999 48 Male 4/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/3/2003 46 Female 128 lb 4/16/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 11/1/2001 50 Female 4/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/3/2003 46 Female 128 lb 4/22/2010 United States
Primary
Concomitant
Tooth Extraction Other Serious 7/16/2008 68 Female 110 lb 5/5/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Tooth Extraction Hospitalization 10/13/2009 70 Female 5/5/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/14/1999 48 Male 5/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Hospitalization Female 5/14/2010 Other Health Professional France
Primary
Secondary
Venous Thrombosis Other Serious 12/12/2001 65 Male 6/9/2010 United States
Primary
Secondary
Concomitant
Tooth Infection Other Serious 1/7/2010 77 Male 6/25/2010 Other Health Professional France
Primary
Concomitant

Drug Data