Cyclophosphamide combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myocardial Infarction Other Serious 12/1/2002 79 Female 176 lb 1/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 52 Male 2/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 52 Male 2/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/4/2005 49 Female 3/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Paraneoplastic Syndrome Hospitalization 9/19/2003 45 Female 139 lb 3/15/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 52 Male 4/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/26/2006 70 Male 5/12/2006 Pharmacist United Kingdom
Primary
Concomitant
Swelling Other Serious 4/13/2006 51 Female 5/24/2006 Physician Portugal
Primary
Concomitant
Staphylococcal Infection Death 5/8/2006 82 Male 6/20/2006 Other Health Professional Sweden
Primary
Concomitant
Vaginal Exfoliation Hospitalization 5/23/2006 Female 139 lb 7/13/2006 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Life Threatening 12/1/2000 Female 8/14/2006
Primary
Secondary
Concomitant
Tachycardia Life Threatening 6/8/2006 2 Female 10/11/2006 Consumer United States
Primary
Concomitant
Death Death Male 11/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death Male 11/3/2006
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Death Male 11/9/2006 United Kingdom
Primary
Secondary
Concomitant
Death Death Male 11/21/2006 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 3/21/2007 63 Male 4/2/2007 Physician United Kingdom
Primary
Concomitant
Septic Shock Other Serious 73 Female 4/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Required Intervention 73 Female 4/20/2007 United States
Primary
Secondary
Concomitant
Septic Shock Required Intervention 73 Female 4/20/2007 United States
Primary
Secondary
Concomitant
Death Death Male 5/16/2007 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Arterial Pressure Increased Other Serious 33 Female 8/1/2007 Korea, Republic Of
Primary
Concomitant
Pain In Jaw Other Serious 1/1/2007 Female 181 lb 8/10/2007 Physician United Kingdom
Primary
Concomitant
Pain In Jaw Other Serious 1/1/2007 Female 181 lb 9/18/2007 Physician United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 6/15/2005 66 Female 10/16/2007 Physician Japan
Primary
Secondary
Concomitant
Viral Dna Test Positive Other Serious 2/1/2005 66 Female 10/24/2007 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 73 Female 11/6/2007 Physician United States
Primary
Secondary
Concomitant
Sensation Of Foreign Body Other Serious 2/1/2005 66 Female 10/24/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/20/2007 Male 1/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Peritonitis Required Intervention 64 Male 1/30/2008 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 12/20/2007 Male 3/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 3/21/2007 63 Male 3/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 1/29/2007 Male 176 lb 4/23/2008 Physician United States
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization 4/18/2008 Male 158 lb 5/9/2008 Other Health Professional United Kingdom
Primary
Concomitant
Venous Thrombosis Other Serious 50 Male 5/9/2008 Physician United Kingdom
Primary
Concomitant
Systemic Inflammatory Response Syndrome Life Threatening 5/28/2008 58 Male 6/18/2008 Pharmacist United States
Primary
Secondary
Concomitant
Ascites Hospitalization 5/30/2008 Male 7/7/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Tongue Paralysis Other Serious 3/1/2008 32 Female 7/11/2008 Consumer United States
Primary
Secondary
Concomitant
Ascites Hospitalization 5/30/2008 Male 7/30/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Ascites Hospitalization 5/30/2008 Male 8/26/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 9/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Disability 5/7/2008 80 Female 154 lb 9/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 4/1/2000 64 Male 10/10/2008 Physician Australia
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Disability 5/7/2008 80 Female 10/6/2008 United Kingdom
Primary
Secondary
Concomitant
Wegener's Granulomatosis Other Serious 8/18/2008 60 Male 10/24/2008 Sweden
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 7/19/2007 49 Female 105 lb 8/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 7/1/2007 44 Male 11/24/2008
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 49 Male 8/7/2008 Japan
Primary
Secondary
Concomitant
Ascites Hospitalization 5/30/2008 Male 12/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 12/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hyperammonaemic Encephalopathy Death 69 Male 12/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Alkalosis Death 69 Male 12/12/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 12/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hyperammonaemic Encephalopathy Life Threatening 69 Male 1/6/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Respiratory Alkalosis Death 69 Male Physician Australia
Primary
Secondary
Concomitant
Respiratory Alkalosis Death 69 Male 1/8/2009 Physician Australia
Primary
Secondary
Concomitant
Platelet Count Decreased Death 4/14/2008 72 Male 2/9/2009 Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 12/15/2007 32 Female 3/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyperammonaemic Encephalopathy Life Threatening 69 Male 4/24/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Intestinal Ischaemia Life Threatening 72 Male 134 lb 5/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intestinal Ischaemia Life Threatening 72 Male 134 lb 5/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intestinal Ischaemia Life Threatening 72 Male 5/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intestinal Ischaemia Life Threatening 72 Male 5/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Hospitalization 31 Male 6/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious Female 6/22/2009 Other Health Professional United States
Primary
Concomitant
Fatigue Life Threatening 10/23/2008 60 Female 220 lb 7/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/3/2009 Female 7/28/2009 Physician Japan
Primary
Secondary
Concomitant
Leukocytosis Other Serious 42 Female 8/5/2009 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Other Serious Female 7/31/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 5/8/2008 70 Female 9/1/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 5/8/2008 70 Female 9/3/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 69 Female 9/17/2009 United States
Primary
Concomitant
Partial Seizures Other Serious 69 Male 10/12/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 6/25/2007 69 Female 10/9/2009 United States
Primary
Concomitant
Platelet Count Decreased Death 5/2/2008 72 Male 10/14/2009 Japan
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 69 Female 10/16/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 10/26/2009 United States
Primary
Concomitant
Shock Death Male 11/4/2009 Lawyer United States
Primary
Concomitant
Partial Seizures Other Serious 69 Male 11/11/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Ascites Hospitalization 5/30/2008 Male 11/12/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 11/12/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 11/9/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 11/17/2009 United States
Primary
Concomitant
Febrile Neutropenia Other Serious 6/4/2008 11/30/2009 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 12/1/2009 United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 8/20/2009 Female 147 lb 12/18/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 8/20/2009 Female 147 lb 12/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Vasculitis Other Serious 11/1/2007 63 Male 1/8/2010 Lawyer United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 8/20/2009 Female 123 lb 1/8/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 7/4/2009 52 Male 1/8/2010 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 8/20/2009 Female 123 lb 1/26/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Bone Marrow Failure Death 78 Female 2/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Thrombocytopenia Death 74 Male 2/10/2010 Lawyer United States
Primary
Concomitant
White Blood Cell Count Increased Required Intervention 63 Male 1/28/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 5/12/2005 Male 136 lb 2/24/2010 Physician United States
Primary
Concomitant
Pancytopenia Other Serious 8/1/2009 74 Male 170 lb 2/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Other Serious 8/1/2009 Male 170 lb 3/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serum Ferritin Increased Other Serious 11/26/2009 74 Male 170 lb 2/26/2010 United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Other Serious 8/28/2009 74 Male 3/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vitamin B12 Increased Other Serious 74 Male 3/6/2010 United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Other Serious 8/1/2009 74 Male 170 lb 3/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/12/2005 Male 136 lb 3/18/2010 Physician United States
Primary
Concomitant
Paraproteinaemia Other Serious 8/28/2009 74 Male 3/18/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Other Serious 8/28/2009 74 Male 3/15/2010 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 7/17/2007 Male 62 lb 3/22/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Paraproteinaemia Other Serious 8/1/2009 74 Male 170 lb 3/15/2010 United Kingdom
Primary
Secondary
Concomitant
Paraproteinaemia Other Serious 74 Male 3/20/2010 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/12/2005 Male 136 lb 3/30/2010 Physician United States
Primary
Concomitant
Vasculitis Other Serious 11/1/2007 63 Male 262 lb 3/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/11/2010 82 Female 125 lb 3/30/2010 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 8/4/2009 61 Female 134 lb 4/8/2010 Pharmacist Japan
Primary
Concomitant
Weight Decreased Other Serious 5/12/2005 60 Male 136 lb 4/9/2010 Other Health Professional United States
Primary
Concomitant
Bone Pain Hospitalization 4/18/2008 64 Male 158 lb 4/27/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization Female 125 lb 4/28/2010 Physician United Kingdom
Primary
Concomitant
Muscle Spasms Hospitalization 4/18/2008 64 Male 158 lb 4/29/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization 4/18/2008 64 Male 158 lb 5/14/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization 4/18/2008 64 Male 158 lb 5/20/2010 Physician United States
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 3/15/2010 70 Male 161 lb 7/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Extremity Hospitalization 1/26/2010 48 Male 150 lb 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 7/7/2010 7/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Extremity Hospitalization 1/26/2010 48 Male 150 lb 7/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 4/5/2010 55 Male 123 lb 8/3/2010 Physician Japan
Primary
Secondary
Concomitant
Tremor Other Serious 8/18/2010 Italy
Primary
Secondary
Concomitant
Vasculitis Other Serious 11/1/2007 63 Male 262 lb 10/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/9/2010 65 Female 10/27/2010 Physician Japan
Primary
Secondary
Concomitant
Epistaxis Hospitalization 6/16/2010 71 Female 212 lb 10/28/2010 Physician South Africa
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 5/30/2008 67 Male 12/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Therapeutic Response Decreased Death 83 Female 144 lb 2/22/2011 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 83 Female 144 lb 2/22/2011 Other Health Professional United States
Primary
Concomitant
Herpes Zoster Other Serious 46 Female 3/18/2011 Physician Brazil
Primary
Secondary
Concomitant
Ear Discomfort 7/1/2008 68 Male 8/27/2010 Pharmacist United States
Primary
Concomitant
Myelodysplastic Syndrome Hospitalization 1/10/2011 82 Male 5/14/2011 Other Health Professional Australia
Primary
Secondary
Concomitant
Ascites Hospitalization 4/10/2008 67 Male 197 lb 5/18/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 1/10/2011 82 Male 198 lb 5/19/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Bone Lesion Other Serious 12/16/2005 61 Male 136 lb 5/19/2011 Other Health Professional United States
Primary
Concomitant
Myelodysplastic Syndrome Death 1/10/2011 82 Male 5/19/2011 Other Health Professional Australia
Primary
Secondary
Concomitant
Osteopenia 6/1/2010 60 Female 263 lb 5/26/2011 Consumer United States
Primary
Concomitant
Pulmonary Embolism Death 2/10/2011 73 Male 203 lb 6/15/2011 Physician Japan
Primary
Concomitant
Intestinal Obstruction Hospitalization 4/1/2011 68 Male 137 lb 6/16/2011 Consumer Italy
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Hospitalization 1/10/2011 82 Male 7/1/2011 Physician Australia
Primary
Secondary
Concomitant
Pulmonary Embolism Death 2/10/2011 73 Male 203 lb 7/6/2011 Physician Japan
Primary
Concomitant
Constipation Other Serious 3/10/2011 75 Male 7/12/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 4/16/2011 59 Female 7/13/2011 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Death 2/10/2011 73 Male 203 lb 7/22/2011 Physician Japan
Primary
Concomitant
Muscle Haemorrhage Other Serious 64 Male 7/24/2011 Other Health Professional Japan
Primary
Secondary
Interstitial Lung Disease Hospitalization 6/21/2007 63 Male 139 lb 7/27/2011 Physician Japan
Primary
Concomitant
Acidosis Hyperchloraemic Hospitalization 12/16/2005 61 Male 136 lb 8/8/2011 Other Health Professional United States
Primary
Concomitant
Rash Other Serious 4/1/2004 52 Female 171 lb 8/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Osteosclerosis Other Serious 12/16/2005 61 Male 136 lb 8/26/2011 Physician United States
Primary
Concomitant
Epistaxis Hospitalization 79 Female 9/1/2011 Other Health Professional United Kingdom
Primary
Secondary

Drug Data