Cyclophosphamide combined with Vindesine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Aspergillosis Death Male 11/16/2006 Consumer Japan
Primary
Secondary
Aspergillosis Death Male 11/17/2006 Consumer Japan
Primary
Secondary
Pulmonary Fibrosis Hospitalization 50 Female 12/4/2006 Physician France
Primary
Concomitant
Pyrexia Hospitalization 10/10/2006 79 Male 1/3/2007 Physician Japan
Primary
Concomitant
Acute Myeloid Leukaemia Other Serious 1/1/2006 64 Male 4/18/2007 Other Health Professional Japan
Primary
Secondary
Mycobacterial Infection Other Serious 1/1/2003 63 Female 4/18/2007 Other Health Professional Japan
Primary
Secondary
Restrictive Pulmonary Disease Hospitalization 2/11/2007 65 Male 157 lb 5/14/2007 Physician France
Primary
Secondary
Concomitant
Tongue Disorder Hospitalization 2/11/2007 65 Male 157 lb 5/17/2007 Physician France
Primary
Secondary
Concomitant
Tongue Disorder Hospitalization 2/11/2007 65 Male 157 lb 6/18/2007 Physician France
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 4/1/2005 13 Male 7/2/2007 Other Health Professional United States
Primary
Secondary
Tongue Haemorrhage Hospitalization 2/11/2007 65 Male 157 lb 8/21/2007 Physician France
Primary
Secondary
Concomitant
Systemic Candida Other Serious 26 Male 11/8/2007 Other Health Professional Germany
Primary
Secondary
Systemic Candida Hospitalization 26 Male 11/15/2007 Germany
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 26 Male 11/21/2007 Germany
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 10/16/2007 Female 3/21/2008 Other Health Professional France
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 3/18/2008 Male 4/25/2008 Physician United Kingdom
Primary
Secondary
Pyrexia Other Serious 5 Female 5/13/2008
Primary
Secondary
Concomitant
Pyrexia Other Serious 5/19/2008 Physician Germany
Primary
Concomitant
Pyrexia Other Serious 5/19/2008 Physician Germany
Primary
Concomitant
Pyrexia Other Serious 5/19/2008 Physician Germany
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 5/1/2008 56 Female 275 lb 7/23/2008 Consumer United States
Primary
Concomitant
Embolism Hospitalization 1/11/2008 60 Female 8/14/2008 Consumer Japan
Primary
Secondary
Bronchopulmonary Aspergillosis Other Serious 8/14/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 8/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 8/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 8/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 8/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Fungal Sepsis Death 8/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 8/15/2008 Physician United Kingdom
Primary
Secondary
Candida Pneumonia Other Serious 8/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 8/1/2006 Female 128 lb 9/17/2008 Consumer United Kingdom
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Hospitalization 8/12/2008 Male 9/17/2008 Physician United Kingdom
Primary
Secondary
Urinary Tract Infection Other Serious 1/1/2005 56 Female 275 lb 9/19/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 10/1/2007 54 Male 209 lb 10/14/2008 Other Health Professional France
Primary
Concomitant
Vision Blurred Other Serious 8/24/2008 76 Female 10/20/2008 Other Health Professional Belgium
Primary
Concomitant
Nausea Hospitalization 8/13/2006 Female 128 lb 11/20/2008 Consumer United Kingdom
Primary
Secondary
Vision Blurred Other Serious 8/24/2008 76 Female 11/25/2008 Other Health Professional Belgium
Primary
Concomitant
Mucosal Inflammation Hospitalization 11/19/2008 Male 12/16/2008 Consumer United Kingdom
Primary
Secondary
Mucosal Inflammation Hospitalization 3/14/2008 Female 97 lb 12/16/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/22/2008
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/22/2008
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/22/2008
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/22/2008
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/22/2008
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/22/2008
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/22/2008
Primary
Secondary
Concomitant
Transfusion Reaction Hospitalization 11/20/2008 Male 12/23/2008 Physician United Kingdom
Primary
Secondary
Stomatitis Other Serious 12/23/2008
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/23/2008
Primary
Secondary
Concomitant
Polyneuropathy Hospitalization Female 12/24/2008 Physician Germany
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 12/21/2008 4 Male 44 lb 1/7/2009 Physician Germany
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 55 Male 2/2/2009 Other Health Professional Austria
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 55 Male 2/10/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 1/16/2009 Female 2/24/2009 Physician United Kingdom
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Hospitalization 8/12/2008 Male 2/27/2009 Physician United Kingdom
Primary
Secondary
Diverticulitis Hospitalization 1/2/2009 Male 3/5/2009 Physician United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 55 Male 3/26/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Lacunar Infarction Other Serious 8/24/2008 76 Female 3/19/2009 Other Health Professional Belgium
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 55 Male 4/7/2009 Austria
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 4/14/2009 Consumer United Kingdom
Primary
Secondary
Acute Promyelocytic Leukaemia Other Serious 53 Male 4/23/2009 Other Health Professional France
Primary
Secondary
Acute Promyelocytic Leukaemia Other Serious 51 Male 4/23/2009 Other Health Professional France
Primary
Secondary
Acute Promyelocytic Leukaemia Other Serious 48 Female 4/23/2009 Other Health Professional France
Primary
Secondary
Acute Promyelocytic Leukaemia Other Serious 20 Male 4/23/2009 Other Health Professional France
Primary
Secondary
Acute Promyelocytic Leukaemia Other Serious 36 Male 4/23/2009 Other Health Professional France
Primary
Secondary
Febrile Neutropenia Other Serious 4/27/2009 Consumer United Kingdom
Primary
Secondary
Haematotoxicity Death 5/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Radiation Mucositis Hospitalization 12/1/2008 44 Female 6/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 30 Male 7/13/2009 Consumer Japan
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Life Threatening 7/28/2009 Male 8/11/2009 Physician United Kingdom
Primary
Secondary
Pneumonia Other Serious 8/1/1997 31 Male 8/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Life Threatening 7/28/2009 Male 8/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Life Threatening 7/28/2009 Male 9/3/2009 Physician France
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 5/23/2009 Female 10/9/2009 Physician United Kingdom
Primary
Secondary
Visual Impairment Life Threatening 7/28/2009 Male 10/14/2009 Physician France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 7/28/2009 Male 10/29/2009 Physician France
Primary
Secondary
Concomitant
Pneumococcal Infection Other Serious 5/18/2009 28 Male 10/29/2009 Other Health Professional France
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 7/28/2009 Male 12/1/2009 Physician France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/26/2008 Male 198 lb 12/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Paraesthesia Disability 10/3/2009 Male 1/19/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Increased Other Serious 1/1/2010 57 Male 9/28/2010 Physician Belgium
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 1/1/2010 10/21/2010 Physician Belgium
Primary
Secondary
Concomitant
Precursor T-lymphoblastic Lymphoma/leukaemia Other Serious 12 2/15/2011 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Death 5 Male 3/18/2011 Other Health Professional Japan
Primary
Secondary
Skin Erosion Death Male 4/1/2011 Other Health Professional Japan
Primary
Secondary
Agranulocytosis Hospitalization 2/4/2011 64 Male 4/8/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Death 4/11/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Agranulocytosis Hospitalization 2/4/2011 64 Male 4/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Precursor T-lymphoblastic Lymphoma/leukaemia Death 11 Male 4/26/2011 Other Health Professional Japan
Primary
Secondary
Cd4 Lymphocytes Increased Other Serious Male 5/13/2011 Consumer Germany
Primary
Secondary
Concomitant
Cytomegalovirus Chorioretinitis Other Serious Male 5/13/2011 Consumer Germany
Primary
Secondary
Concomitant
Precursor T-lymphoblastic Lymphoma/leukaemia Death 11 Male 5/24/2011 Other Health Professional Japan
Primary
Secondary
Visual Acuity Reduced Other Serious 12/15/2010 32 Male 148 lb 6/17/2011 Physician Germany
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Life Threatening 2/11/2011 51 Male 6/24/2011 Other Health Professional Germany
Primary
Concomitant
Drug Effect Decreased Death 2/1/2009 12 Male 7/8/2011 Physician Japan
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 7/14/2011 Other Health Professional France
Primary
Secondary
Toxicity To Various Agents Death 7/14/2011 Other Health Professional France
Primary
Secondary
Toxicity To Various Agents Death 7/14/2011 Other Health Professional France
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Death 8/22/2011 Other Health Professional Switzerland
Primary
Secondary
Acute Lymphocytic Leukaemia Hospitalization 2/11/2011 51 Male 8/24/2011 Other Health Professional Germany
Primary
Concomitant
Haemorrhage Death 9/2/2011 Other Health Professional France
Primary
Secondary
Concomitant
Bacterial Sepsis Death 9/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bronchopulmonary Aspergillosis Death 63 Female 9/2/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Death 9/6/2011 Other Health Professional France
Primary
Secondary
Concomitant
Infection Death 9/9/2011 Other Health Professional France
Primary
Secondary
Concomitant
Lung Infection Hospitalization 9/16/2011 59 Male 143 lb 9/22/2011 Consumer United Kingdom
Primary
Concomitant
Haematotoxicity Death 12/21/2011 Physician Denmark
Primary
Secondary
Neurotoxicity Death 12/27/2011 Physician France
Primary
Secondary
Concomitant
Death Death 2/8/2012 Other Health Professional France
Primary
Secondary
Lung Neoplasm Malignant Other Serious 2/8/2012 Other Health Professional France
Primary
Secondary
Sepsis Death 2/9/2012 Other Health Professional France
Primary
Secondary
Sepsis Death 2/9/2012 Other Health Professional France
Primary
Secondary
Sepsis Death 2/9/2012 Other Health Professional France
Primary
Secondary
Lung Infection Hospitalization 6/8/2011 60 Female 143 lb 2/13/2012 China
Primary
Secondary
Concomitant
Lung Infection Death 3/6/2012 Other Health Professional China
Primary
Concomitant
Acute Myelomonocytic Leukaemia Hospitalization 2/28/2012 48 Male 4/6/2012 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Other Serious 71 Male 4/13/2012 Physician China
Primary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 4/23/2012 47 Male 5/8/2012 Consumer France
Primary
Concomitant
Anaemia Other Serious 5/10/2012 Other Health Professional China
Primary
Secondary
Concomitant
Off Label Use Other Serious 5/10/2012 Other Health Professional China
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 5/10/2012 Other Health Professional China
Primary
Secondary
Hepatotoxicity Other Serious 5/10/2012 Other Health Professional China
Primary
Secondary
Concomitant
Sepsis Other Serious 5/11/2012 Other Health Professional China
Primary
Secondary
Concomitant
Pulmonary Toxicity Other Serious 5/11/2012 Other Health Professional China
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 5/11/2012 Other Health Professional China
Primary
Secondary
Concomitant
Off Label Use Other Serious 5/11/2012 Other Health Professional China
Primary
Secondary
Concomitant
Off Label Use Other Serious 5/11/2012 Other Health Professional China
Primary
Secondary
Concomitant
Death Death Male 5/14/2012 Physician Germany
Primary
Secondary
Death Other Serious 6/1/2012 Denmark
Primary
Secondary
Blast Cell Crisis Other Serious 55 Male 6/26/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Skin Lesion Other Serious 55 Male 6/26/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 4/23/2012 47 Male 159 lb 6/27/2012 Physician France
Primary
Concomitant
Circulatory Collapse Death 10/15/2009 60 Male 8/3/2012 Physician China
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 3/2/2012 76 Male 8/6/2012 Physician France
Primary
Secondary
Death Death 8/13/2012 Other Health Professional France
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Recurrent Death 8/13/2012 Other Health Professional France
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Recurrent Other Serious 8/13/2012 Other Health Professional France
Primary
Secondary
Concomitant
Puncture Site Infection Hospitalization 12/5/2008 8/15/2012 Physician Germany
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 6/20/2010 55 Male 143 lb 8/21/2012 Other Health Professional China
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 5/28/2010 55 Female 143 lb 8/21/2012 Other Health Professional China
Primary
Secondary
Concomitant
Pneumocystis Jirovecii Pneumonia Death NotSpecified 5/13/2013 Physician Ch
Primary
Secondary
Leukaemia Recurrent Death 10/12/2011 2 Male 30 lb 10/16/2012 Physician De
Primary
Secondary
Concomitant
Asthma Other Serious Female 10/24/2012 Physician Fr
Primary
Concomitant
Toxicity To Various Agents Death 62 Female 11/14/2012 Other Health Professional Cn
Primary
Secondary
Febrile Neutropenia Death 11/20/2012 Other Health Professional Fr
Primary
Secondary
Thrombocytopenia Other Serious 11/30/2012 Physician Country Not Specified
Primary
Secondary
Systemic Candida Hospitalization 8/7/2012 57 Male 227 lb 12/17/2012 Physician Fr
Primary
Secondary
Neurotoxicity Other Serious NotSpecified 1/14/2013 Other Health Professional Country Not Specified
Primary
Secondary
Pneumomediastinum Other Serious 24 Female 2/14/2013 Other Health Professional Be
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 11/26/2012 65 Male 2/4/2013 Other Health Professional Fr
Primary
Secondary
Concomitant

Drug Data