Cyclophosphamide combined with Velcade

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Therapy Non-responder Life Threatening 12/3/2005 54 Male 142 lb 1/9/2006 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 1/6/2006 Female 1/10/2006 Other Health Professional United States
Primary
Secondary
Sciatica Hospitalization 2/1/2005 56 Male 1/25/2006 Physician Canada
Primary
Secondary
Therapy Non-responder Life Threatening 12/3/2005 54 Male 142 lb 1/30/2006 Physician Malaysia
Primary
Concomitant
Hepatic Neoplasm Hospitalization 1/25/2006 74 Male 2/1/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Plasmacytoma Hospitalization 1/25/2006 74 Male 2/9/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 1/9/2005 42 Male 2/22/2006 Physician Denmark
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/9/2005 42 Male 3/6/2006 Physician Denmark
Primary
Secondary
Concomitant
Syncope Hospitalization 7/13/2005 68 Male 3/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/3/2006 77 Male 4/6/2006 Other Health Professional United States
Primary
Secondary
Thrombocytopenia Hospitalization 2/12/2006 77 Male 4/13/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/1/2006 77 Male 4/18/2006 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/25/2006 88 Male 4/14/2006 Physician United States
Primary
Secondary
Pneumonia Hospitalization 4/3/2006 77 Male 159 lb 4/19/2006 Physician United States
Primary
Secondary
Staphylococcal Infection Hospitalization 4/19/2006 68 Male 4/26/2006 Other Health Professional United States
Primary
Secondary
Neurological Symptom Other Serious 4/21/2006 63 4/28/2006 Physician Netherlands
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 4/15/2006 54 Female 97 lb 5/5/2006 Physician France
Primary
Secondary
Pyrexia Hospitalization 3/11/2006 77 Male 5/8/2006 Physician United States
Primary
Secondary
Neutropenia Hospitalization 12/15/2005 26 Male 5/11/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/26/2006 70 Male 5/12/2006 Pharmacist United Kingdom
Primary
Concomitant
Neutropenia Hospitalization 4/28/2006 58 Male 203 lb 5/16/2006 Physician Germany
Primary
Secondary
Concomitant
Urethral Haemorrhage Other Serious 5/5/2006 59 Male 5/16/2006 Physician Germany
Primary
Secondary
Urethral Haemorrhage Other Serious 5/4/2006 59 Male 5/19/2006 Physician Germany
Primary
Secondary
Leukopenia Other Serious 5/12/2006 62 Female 5/22/2006 Physician Germany
Primary
Secondary
Thrombocytopenia Hospitalization 4/15/2006 54 Female 97 lb 5/23/2006 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/19/2006 59 Male 143 lb 6/16/2006 Physician France
Primary
Secondary
Thrombocytopenia Hospitalization 5/19/2006 59 Male 143 lb 6/26/2006 Physician France
Primary
Secondary
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 6/29/2006 Physician Germany
Primary
Secondary
Concomitant
Urethral Haemorrhage Other Serious 5/4/2006 59 Male 144 lb 6/29/2006 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Required Intervention 3/1/2005 73 Male 6/26/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/20/2006 1 7/10/2006 Physician France
Primary
Secondary
Inappropriate Antidiuretic Hormone Secretion Life Threatening 6/30/2006 61 Male 190 lb 7/13/2006 Physician France
Primary
Secondary
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 7/13/2006 Physician Germany
Primary
Secondary
Concomitant
Ventricular Hypertrophy Death 4/10/2004 70 Male 7/20/2006 Physician United States
Primary
Secondary
Cluster Headache Hospitalization 7/10/2006 Male 236 lb 7/21/2006 Physician Germany
Primary
Secondary
Renal Failure Life Threatening 8/19/2004 47 Female 7/25/2006 Physician United States
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Life Threatening 6/30/2006 61 Male 190 lb 7/28/2006 Physician France
Primary
Secondary
Chest Pain Hospitalization 3/25/2006 73 Female 137 lb 7/31/2006 Physician United States
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 4/21/2006 63 Male 8/4/2006 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/24/2006 59 Female 150 lb 8/2/2006 Physician Canada
Primary
Secondary
Concomitant
Vasculitis Hospitalization 7/16/2006 68 Male 8/3/2006 Other Health Professional United States
Primary
Secondary
Respiratory Failure Death 61 Male 8/4/2006 Australia
Primary
Secondary
Concomitant
Urethral Haemorrhage Other Serious 5/4/2006 59 Male 144 lb 8/3/2006 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/25/2006 88 Male 7/26/2006 Physician United States
Primary
Secondary
Syncope Hospitalization 7/14/2006 63 Male 166 lb 8/7/2006 Physician United States
Primary
Secondary
Vomiting Hospitalization 7/24/2006 59 Female 150 lb 8/10/2006 Physician Canada
Primary
Secondary
Concomitant
Extravasation Hospitalization 6/9/2006 58 8/10/2006 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Required Intervention 2/1/2000 52 Male 8/7/2006 Physician United States
Primary
Secondary
Concomitant
Pseudomonal Sepsis Life Threatening 7/17/2006 61 Male 183 lb 8/17/2006 Physician France
Primary
Secondary
Stem Cell Transplant Required Intervention 4/21/2006 63 Male 170 lb 8/21/2006 Physician United States
Primary
Secondary
Concomitant
Cluster Headache 7/10/2006 54 Male 236 lb 8/23/2006 Physician Germany
Primary
Secondary
Extravasation Hospitalization 6/9/2006 58 8/31/2006 Physician Germany
Primary
Secondary
Concomitant
Chest Pain Hospitalization 8/25/2006 53 Male 9/6/2006 Physician United States
Primary
Secondary
Renal Failure Hospitalization 8/23/2006 42 Female 9/7/2006 Physician France
Primary
Secondary
Transient Ischaemic Attack Other Serious 4/21/2006 63 Male 9/4/2006 Physician Netherlands
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/28/2006 58 Male 203 lb 9/7/2006 Physician Germany
Primary
Secondary
Concomitant
Pseudomonal Sepsis Life Threatening 7/17/2006 61 Male 183 lb 9/14/2006 Physician France
Primary
Secondary
White Blood Cell Count Abnormal Hospitalization 8/4/2006 59 Female 157 lb 9/14/2006 Physician United States
Primary
Secondary
Concomitant
Gastritis Hospitalization 8/4/2006 59 Female 157 lb 9/20/2006 Physician United States
Primary
Secondary
Concomitant
Colitis Hospitalization 8/14/2006 69 Male 146 lb 9/25/2006 Physician United States
Primary
Secondary
Concomitant
Pseudomonal Sepsis Life Threatening 7/17/2006 61 Male 183 lb 9/27/2006 Physician France
Primary
Secondary
Renal Failure Hospitalization 8/23/2006 42 Female 10/5/2006 Physician France
Primary
Secondary
Coronary Arterial Stent Insertion Hospitalization 8/25/2006 53 Male 10/5/2006 Physician United States
Primary
Secondary
Colitis Hospitalization 8/14/2006 69 Male 146 lb 10/11/2006 Physician United States
Primary
Secondary
Concomitant
Gastritis Hospitalization 8/4/2006 59 Female 157 lb 10/10/2006 Physician United States
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 3/25/2006 73 Female 137 lb 10/11/2006 Physician United States
Primary
Secondary
Concomitant
Escherichia Infection Hospitalization 10/2/2006 56 Female 115 lb 10/13/2006 Physician France
Primary
Secondary
Pyrexia Hospitalization 6/19/2006 72 Female 10/23/2006 Physician United States
Primary
Secondary
Pancytopenia Hospitalization 10/4/2006 52 Male 10/20/2006 Physician United States
Primary
Secondary
Sinus Tachycardia Hospitalization 8/21/2006 60 Female 10/20/2006 Physician United States
Primary
Secondary
Cellulitis Hospitalization 10/7/2006 69 Male 10/23/2006 Physician United States
Primary
Secondary
Malignant Neoplasm Progression Hospitalization 10/2/2006 56 Female 115 lb 10/23/2006 Physician France
Primary
Secondary
Pleuritic Pain Hospitalization 8/19/2006 61 Female 161 lb 10/25/2006 Physician United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 10/2/2006 56 Female 115 lb 10/26/2006 Physician France
Primary
Secondary
Urticaria Hospitalization 10/23/2006 69 Male 10/31/2006 Physician United States
Primary
Secondary
Pancytopenia Hospitalization 10/4/2006 52 Male 10/30/2006 Physician United States
Primary
Secondary
Sinus Tachycardia Hospitalization 8/7/2006 38 Male 268 lb 11/7/2006 Physician Canada
Primary
Secondary
Pituitary Tumour Benign Life Threatening 6/30/2006 61 Male 190 lb 11/8/2006 Physician France
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 7/26/2004 59 Female 11/9/2006 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 9/30/2006 50 Female 200 lb 11/9/2006 Physician United States
Primary
Secondary
Herpes Zoster Ophthalmic Hospitalization 11/7/2006 54 Male 220 lb 11/14/2006 Physician Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/4/2006 60 Female 11/27/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 10/29/2006 52 Male 12/6/2006 Physician United States
Primary
Secondary
Tachycardia Hospitalization 9/30/2006 50 Female 200 lb 12/6/2006 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 10/30/2006 63 Male 229 lb 12/7/2006 Physician United States
Primary
Secondary
Herpes Zoster Disseminated Hospitalization 11/7/2006 54 Male 220 lb 12/8/2006 Physician Canada
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 4/28/2006 61 Male 176 lb 12/21/2006 Physician France
Primary
Secondary
Herpes Zoster Hospitalization 9/9/2006 61 12/21/2006 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/2/2006 52 Male 12/27/2006 Physician United States
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Life Threatening 6/30/2006 61 Male 190 lb 12/28/2006 Physician France
Primary
Secondary
Sinus Tachycardia Hospitalization 8/7/2006 38 Male 268 lb 12/28/2006 Physician Canada
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Hospitalization 11/27/2006 41 Male 152 lb 12/28/2006 Physician France
Primary
Secondary
Concomitant
Skin Hyperpigmentation Other Serious 4/6/2006 54 Female 97 lb 12/28/2006 Physician France
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 7/16/2006 68 Male 1/2/2007 Physician United States
Primary
Secondary
Concomitant
Urticaria Hospitalization 10/23/2006 69 Male 12/28/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 11/15/2006 66 Male 193 lb 1/3/2007 Physician United States
Primary
Secondary
Concomitant
Oesophageal Candidiasis Hospitalization 12/23/2006 56 Female 1/8/2007 Physician France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/30/2006 63 Male 229 lb 1/22/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/13/2006 47 Female 1/22/2007 Physician France
Primary
Secondary
Purpura Hospitalization 12/23/2006 56 Female 104 lb 1/24/2007 Physician France
Primary
Secondary
Concomitant
Skin Hyperpigmentation Other Serious 4/6/2006 54 Female 97 lb 1/25/2007 Physician France
Primary
Secondary
Staphylococcal Bacteraemia Hospitalization 11/4/2006 60 Female 1/25/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/3/2006 51 Female 106 lb 2/8/2007 Other Health Professional France
Primary
Secondary
Concomitant
Stem Cell Transplant Hospitalization 8/14/2006 69 Male 146 lb 2/9/2007 Physician United States
Primary
Secondary
Concomitant
Urethral Haemorrhage Other Serious 5/4/2006 59 Male 144 lb 2/9/2007 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/3/2006 51 Female 106 lb 2/19/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 11/27/2006 41 Male 152 lb 3/2/2007 Physician France
Primary
Secondary
Concomitant
Skin Hyperpigmentation Other Serious 4/6/2006 54 Female 97 lb 3/2/2007 Physician France
Primary
Secondary
Splenomegaly Hospitalization 2/19/2007 52 Male 3/6/2007 Other Health Professional United States
Primary
Secondary
Pneumonitis Hospitalization 2/11/2007 65 Male 157 lb 3/2/2007 Physician France
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 6/19/2006 72 Female 3/5/2007 Physician United States
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 8/21/2006 60 Female 3/5/2007 Physician United States
Primary
Secondary
Spinal Compression Fracture Other Serious 8/18/2006 68 Male 176 lb 3/7/2007 Physician United States
Primary
Secondary
Concomitant
Cardiomyopathy Disability 12/8/2005 52 Male 3/12/2007 Physician Netherlands
Primary
Secondary
Vomiting Hospitalization 3/1/2007 52 Male 3/12/2007 Physician France
Primary
Secondary
Systemic Candida Other Serious 2/1/2007 72 Male 3/6/2007 Physician United States
Primary
Secondary
Concomitant
Pseudomonas Infection Hospitalization 1/15/2007 47 Female 165 lb 3/20/2007 Physician France
Primary
Secondary
Febrile Bone Marrow Aplasia Hospitalization 1/25/2007 62 Female 143 lb 3/19/2007 Physician France
Primary
Secondary
Pulmonary Mass Hospitalization 2/11/2007 65 Male 157 lb 3/23/2007 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/1/2007 52 Male 159 lb 3/23/2007 Physician France
Primary
Secondary
Ulcer Hospitalization 3/4/2007 28 Female 110 lb 3/23/2007 Physician France
Primary
Secondary
Transplant Hospitalization 1/15/2007 47 Female 165 lb 4/5/2007 Physician France
Primary
Secondary
Oedema Other Serious 10/1/2006 57 Male 4/6/2007 Physician United States
Primary
Secondary
Concomitant
Pneumaturia Hospitalization 2/20/2007 72 Male 4/8/2007 Physician United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 2/1/2007 72 Male 4/4/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/20/2006 52 Female 4/17/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/19/2007 69 Male 4/13/2007 Physician United States
Primary
Secondary
Concomitant
Uterine Leiomyoma Hospitalization 7/14/2006 52 Female 4/19/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Required Intervention 9/1/2004 56 Male 4/13/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/1/2006 62 Male 179 lb 4/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Life Threatening 3/22/2007 58 Male 139 lb 4/27/2007 Physician France
Primary
Secondary
Concomitant
Oedema Other Serious 10/1/2006 57 Male 5/2/2007 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 4/20/2007 40 Male 176 lb 5/2/2007 Physician France
Primary
Secondary
Thrombocytopenia Other Serious 1/1/2006 62 Male 179 lb 5/6/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Life Threatening 3/22/2007 58 Male 139 lb 5/10/2007 Physician France
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/1/2006 52 Male 5/10/2007 Physician United States
Primary
Secondary
Thrombocytopenia Hospitalization 5/19/2006 59 Male 143 lb 5/11/2007 Physician France
Primary
Secondary
Oesophageal Ulcer Hospitalization 12/21/2006 56 Female 104 lb 5/11/2007 Physician France
Primary
Secondary
Concomitant
Neurotoxicity Life Threatening 74 Male 165 lb 5/11/2007 France
Primary
Secondary
Restrictive Pulmonary Disease Hospitalization 2/11/2007 65 Male 157 lb 5/14/2007 Physician France
Primary
Secondary
Concomitant
Tongue Disorder Hospitalization 2/11/2007 65 Male 157 lb 5/17/2007 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/15/2006 51 Male 5/11/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/15/2006 52 Male 5/18/2007 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/5/2006 52 Male 5/21/2007 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 5/12/2007 52 Male 145 lb 5/18/2007 Physician Spain
Primary
Secondary
Nodal Arrhythmia Hospitalization 5/3/2007 72 Female 303 lb 5/23/2007 Physician United States
Primary
Secondary
Pyrexia Hospitalization 9/20/2006 52 Female 5/27/2007 Physician United States
Primary
Secondary
Concomitant
Uterine Leiomyoma Hospitalization 7/14/2006 52 Female 5/27/2007 Physician United States
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 5/15/2007 65 Male 157 lb 5/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Hospitalization 4/30/2007 40 Male 176 lb 5/25/2007 Physician France
Primary
Secondary

Drug Data