Cyclophosphamide combined with Thalidomide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Osteonecrosis Other Serious 56 Male 10/27/2005 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 7/13/2005 68 Male 3/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 52 Male 3/15/2006 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 52 Male 3/24/2006 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 11/28/2003 64 Male 197 lb 4/28/2006 United Kingdom
Primary
Secondary
Concomitant
Melaena Other Serious 60 Female 5/22/2006 Australia
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 52 Male 5/31/2006 United States
Primary
Secondary
Concomitant
Coronary Artery Surgery Hospitalization 4/26/2005 69 Male 4/28/2006 Other Health Professional United States
Primary
Secondary
Graft Versus Host Disease Death 3/28/2003 31 Male 4/27/2006 Japan
Primary
Concomitant
Wound Debridement Other Serious 1/1/2003 61 Male 187 lb 7/21/2006 Physician Germany
Primary
Concomitant
Plasmacytoma Other Serious 54 Male 9/21/2006 Consumer United States
Primary
Secondary
Coronary Artery Occlusion Hospitalization 9/25/2006 70 Male 9/26/2006 Other Health Professional United States
Primary
Secondary
Osteonecrosis Hospitalization 5/5/2005 61 Female 10/3/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/21/2006 64 Male 183 lb 10/9/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/21/2006 64 Male 10/6/2006 United Kingdom
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 9/1/2005 60 Female 10/19/2006 Physician United Kingdom
Primary
Concomitant
Death Death Male 11/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death Male 11/3/2006
Primary
Secondary
Concomitant
Death Death Male 11/21/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/4/2006 60 Female 11/27/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 65 Female 12/8/2006 Greece
Primary
Concomitant
Osteonecrosis Other Serious Male 12/21/2006 Physician Australia
Primary
Concomitant
Thrombocytopenia Hospitalization 65 Female 12/21/2006 Greece
Primary
Concomitant
Venous Thrombosis Limb Other Serious 9/1/2006 16 Female 174 lb 12/15/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 11/15/2006 66 Male 193 lb 1/3/2007 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 67 Male 1/13/2007 United Kingdom
Primary
Concomitant
Treatment Related Secondary Malignancy 54 Male 1/16/2007 United States
Primary
Secondary
Staphylococcal Bacteraemia Hospitalization 11/4/2006 60 Female 1/25/2007 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 73 Male 2/2/2007 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Stem Cell Transplant Hospitalization 8/14/2006 69 Male 146 lb 2/9/2007 Physician United States
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 11/1/2006 64 Male 2/23/2007 Physician Australia
Primary
Concomitant
Spinal Compression Fracture Other Serious 8/18/2006 68 Male 176 lb 3/7/2007 Physician United States
Primary
Secondary
Concomitant
Tremor 5/24/2006 Male 3/28/2007 Other Health Professional United States
Primary
Concomitant
Oedema Other Serious 10/1/2006 57 Male 4/6/2007 Physician United States
Primary
Secondary
Concomitant
Pneumaturia Hospitalization 2/20/2007 72 Male 4/8/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/20/2006 52 Female 4/17/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/19/2007 69 Male 4/13/2007 Physician United States
Primary
Secondary
Concomitant
Uterine Leiomyoma Hospitalization 7/14/2006 52 Female 4/19/2007 Physician United States
Primary
Secondary
Concomitant
No Therapeutic Response Other Serious NotSpecified 4/11/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Lichenoid Keratosis Disability 2/14/2007 44 Male 4/18/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/1/2006 62 Male 179 lb 4/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Other Serious 10/1/2006 57 Male 5/2/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 62 Male 179 lb 5/6/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death Male 5/16/2007 Consumer United States
Primary
Secondary
Concomitant
Neurotoxicity Life Threatening 74 Male 165 lb 5/11/2007 France
Primary
Secondary
No Therapeutic Response Other Serious 5/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/15/2006 52 Male 5/18/2007 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/5/2006 52 Male 5/21/2007 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 5/23/2006 78 Male 161 lb 5/26/2007 Physician United Kingdom
Primary
Concomitant
Tooth Extraction Other Serious 5/23/2006 78 Male 161 lb 5/26/2007 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 9/20/2006 52 Female 5/27/2007 Physician United States
Primary
Secondary
Concomitant
Uterine Leiomyoma Hospitalization 7/14/2006 52 Female 5/27/2007 Physician United States
Primary
Secondary
Concomitant
Neurotoxicity Life Threatening 74 Male 165 lb 5/24/2007 France
Primary
Secondary
Stent Placement Other Serious 10/13/2006 57 Male 218 lb 5/30/2007 Physician United States
Primary
Secondary
Concomitant
Pneumaturia Hospitalization 2/20/2007 72 Male 5/29/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/7/2007 66 Female 257 lb 5/30/2007 Physician United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 12/13/2006 48 Female 5/30/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/14/2006 69 Male 146 lb 5/31/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/19/2007 69 Male 195 lb 5/31/2007 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 11/15/2006 66 Male 193 lb 6/3/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/7/2007 66 Female 257 lb 6/11/2007 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/1/2006 76 Male 6/20/2007 Other Health Professional Finland
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/28/2007 66 Male 6/14/2007 Physician United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 12/13/2006 48 Female 220 lb 6/19/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/7/2007 66 Female 257 lb 6/20/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/28/2007 66 Male 7/6/2007 Physician United States
Primary
Secondary
Concomitant
Sudden Cardiac Death Other Serious 7/11/2007 Physician Germany
Primary
Secondary
Splenomegaly Hospitalization 5/28/2007 66 Male 204 lb 7/17/2007 Physician United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Other Serious 10/13/2006 57 Male 218 lb 7/19/2007 Physician United States
Primary
Secondary
Concomitant
Multi-organ Failure Death 7/19/2007 65 Male 7/20/2007 Physician United Kingdom
Primary
Concomitant
No Therapeutic Response Life Threatening 7/1/2007 67 Male 8/6/2007 Physician United Kingdom
Primary
Secondary
Unresponsive To Stimuli Life Threatening 7/1/2007 67 Male 8/8/2007 Physician United Kingdom
Primary
Concomitant
Splenomegaly Hospitalization 5/28/2007 66 Male 204 lb 8/16/2007 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 66 Male 9/11/2007 Other Health Professional Portugal
Primary
Concomitant
Tooth Extraction Other Serious 7/1/2003 71 Male 9/11/2007 Other Health Professional Portugal
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 12/22/2006 71 Female 124 lb 9/27/2007 Physician United States
Primary
Secondary
Concomitant
West Nile Viral Infection Other Serious 8/18/2006 68 Male 176 lb 9/26/2007 Physician United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Disability 9/19/2007 Male 10/2/2007 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/31/2005 71 Female 134 lb 10/12/2007 Physician United States
Primary
Secondary
Concomitant
Sarcoidosis Life Threatening 7/1/2007 67 Male 10/19/2007 Physician United Kingdom
Primary
Concomitant
Interstitial Lung Disease Disability 9/19/2007 69 Male 10/26/2007 Physician United Kingdom
Primary
Concomitant
Multiple Myeloma Hospitalization 55 Male 11/9/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Enterococcal Hospitalization 7/31/2005 71 Female 134 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2001 27 Male 11/19/2007 Other Health Professional Brazil
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 12/22/2006 71 Female 124 lb 11/19/2007 Physician United States
Primary
Secondary
Concomitant
Rotavirus Infection Hospitalization 8/27/2007 72 Female 118 lb 1/3/2008 Physician United States
Primary
Secondary
Concomitant
Nausea Hospitalization 1/15/2008 69 Male 205 lb 1/30/2008 Physician United States
Primary
Secondary
Concomitant
Death Death 1 1/30/2008 Physician Spain
Primary
Secondary
Venous Thrombosis Limb Other Serious 9/1/2006 16 Female 174 lb 2/21/2008 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Life Threatening 2/8/2008 14 Female 123 lb 3/14/2008 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 66 Male 3/27/2008 Other Health Professional Portugal
Primary
Concomitant
Tooth Extraction Other Serious 7/1/2003 71 Male 3/27/2008 Other Health Professional Portugal
Primary
Concomitant
Pulmonary Embolism Hospitalization 3/24/2008 59 Male 3/26/2008 Other Health Professional United States
Primary
Secondary
Ulcer Other Serious 60 Male 4/1/2008 Other Health Professional Canada
Primary
Concomitant
Colitis Death 6/22/2006 58 Male 84 lb 3/28/2008 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Death 6/22/2006 58 Male 84 lb 4/7/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 66 Male 4/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Gaze Palsy Hospitalization 6/7/2007 82 Male 4/16/2008 Consumer France
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 3/1/2004 66 Male 4/16/2008 Other Health Professional Portugal
Primary
Concomitant
Osteonecrosis Other Serious 7/1/2003 71 Male 4/16/2008 Other Health Professional Portugal
Primary
Concomitant
Eye Disorder Hospitalization 6/7/2007 Male 4/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 4/15/2008 Physician United States
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 6/30/2006 59 Female 240 lb 4/16/2008 Physician United States
Primary
Secondary
Concomitant
Proteinuria Other Serious 3/1/2007 49 Female 4/9/2008 Other Health Professional Australia
Primary
Secondary
Skin Haemorrhage Other Serious 49 Male 4/22/2008 Physician Russian Federation
Primary
Secondary
Urine Output Decreased Hospitalization 1/31/2008 53 Female 137 lb 4/16/2008 Other Health Professional Korea, Democratic People's Republic Of
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 3/7/2008 57 Female 166 lb 4/16/2008 Physician Korea, Democratic People's Republic Of
Primary
Secondary
Concomitant
Hypotension Hospitalization 1/25/2006 66 Male 245 lb 4/23/2008 Physician United States
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 4/25/2008 Physician United States
Primary
Secondary
Concomitant
Viral Infection Hospitalization 3/7/2008 45 Male 354 lb 4/28/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/2/2008 64 Female 166 lb 5/9/2008 Physician Portugal
Primary
Secondary
Viral Infection Hospitalization 3/7/2008 45 Male 354 lb 5/13/2008 Physician United States
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 6/26/2006 59 Female 240 lb 5/13/2008 Physician United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 4/4/2008 67 Male 209 lb 5/20/2008 Physician United States
Primary
Secondary
Concomitant
Hodgkin's Disease Stage Ii Other Serious 2/21/2008 Female 43 lb 6/5/2008 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 4/12/2008 65 Unknown 6/5/2008 Physician Malaysia
Primary
Concomitant
Enteritis Hospitalization 6/30/2006 59 Female 240 lb 6/4/2008 Physician United States
Primary
Secondary
Concomitant
Blood Human Chorionic Gonadotropin Increased Other Serious 4/6/2008 38 Female 6/4/2008 Physician United Kingdom
Primary
Concomitant
Wound Infection Other Serious 4/4/2008 67 Male 209 lb 6/10/2008 Physician United States
Primary
Secondary
Concomitant
Blood Human Chorionic Gonadotropin Increased Other Serious 4/6/2008 38 Female 6/10/2008 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 5/2/2008 55 Female 6/18/2008 Physician Malaysia
Primary
Concomitant
Myocardial Infarction Death 4/12/2008 65 Unknown 6/18/2008 Physician Malaysia
Primary
Concomitant
Thrombocytopenia Other Serious 5/2/2008 55 Female 7/3/2008 Physician Malaysia
Primary
Concomitant
Wound Infection Other Serious 4/4/2008 67 Male 209 lb 7/2/2008 Physician United States
Primary
Secondary
Concomitant
Syncope Other Serious 6/24/2008 Other Health Professional Germany
Primary
Secondary
Guillain-barre Syndrome Hospitalization 47 Male 8/4/2008 Other Health Professional United States
Primary
Secondary
Vena Cava Thrombosis Other Serious 6/6/2005 63 Female 144 lb 7/29/2008 Physician United States
Primary
Secondary
Concomitant
Guillain-barre Syndrome Other Serious 47 Male 8/11/2008 United States
Primary
Secondary
Guillain-barre Syndrome Other Serious 47 Male 8/9/2008 United States
Primary
Secondary
Hodgkin's Disease Stage Ii Other Serious 2 Female 8/15/2008 United States
Primary
Secondary
Hodgkin's Disease Other Serious 10 Female 8/18/2008 Physician United States
Primary
Secondary
Wound Infection Pseudomonas Other Serious 4/4/2008 67 Male 209 lb 8/14/2008 Physician United States
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 47 Male 8/20/2008 Physician United States
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 10 Female 8/27/2008 Physician United States
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 10 Female 8/28/2008 United States
Primary
Secondary
Concomitant
Joint Destruction Other Serious 10 Female 9/22/2008 United States
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 10 Female 9/26/2008 Physician United States
Primary
Secondary
Hodgkin's Disease Other Serious 10 Female 9/30/2008 Physician United Kingdom
Primary
Secondary
Hodgkin's Disease Other Serious 10 Female 10/2/2008 Other Health Professional United States
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 4/1/2000 64 Male 10/10/2008 Physician Australia
Primary
Secondary
Concomitant
Wheelchair User Other Serious 10 Female 10/17/2008 Physician United States
Primary
Secondary
Thrombophlebitis Septic Hospitalization 1/1/2003 58 Male 160 lb 10/31/2008 Physician United States
Primary
Secondary
Vena Cava Thrombosis Other Serious 6/6/2005 63 Female 144 lb 11/6/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/1/2003 Male 11/18/2008 Physician United States
Primary
Secondary
Thrombophlebitis Septic Other Serious 5/28/2003 58 Male 160 lb 11/26/2008 Physician United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 71 Male 12/30/2008 Other Health Professional France
Primary
Concomitant
Thrombophlebitis Septic Other Serious 2/18/2004 58 Male 160 lb 12/23/2008 Physician United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization Male 1/5/2009 Physician France
Primary
Concomitant
Pulmonary Embolism Other Serious 1/7/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Toxicity Hospitalization 71 Male 1/9/2009 Other Health Professional France
Primary
Concomitant

Drug Data