Cyclophosphamide combined with Tamoxifen Citrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Metastases To Liver Death 2/18/2000 57 Female 3/24/2006 Other Health Professional Switzerland
Primary
Secondary
Ventricular Tachycardia Other Serious 3/1/2004 38 Female 4/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vital Capacity Abnormal Disability 2/21/2006 Female 5/22/2006 Physician Japan
Primary
Concomitant
Treatment Related Secondary Malignancy Death 9/8/1998 58 Female 6/23/2006 Other Health Professional Finland
Primary
Secondary
Myelodysplastic Syndrome Hospitalization 12/2/2005 44 Female 124 lb 8/9/2006 Physician Australia
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Hospitalization 11/22/2005 44 Female 124 lb 9/11/2006 Physician Australia
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 64 Female 9/19/2006 Other Health Professional Italy
Primary
Concomitant
Surgery Other Serious 78 Female 9/19/2006 Italy
Primary
Concomitant
Surgery Other Serious 68 Female 9/19/2006 Other Health Professional Italy
Primary
Concomitant
Soft Tissue Infection Disability 7/1/2006 49 Female 9/21/2006 Physician Australia
Primary
Concomitant
Haemorrhage Intracranial Death 1/1/2002 43 Female 9/28/2006 India
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 43 Female 10/13/2006 Physician India
Primary
Secondary
Concomitant
Rheumatoid Factor Positive Other Serious 43 Female 11/1/2006 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 11/22/2005 44 Female 124 lb 11/7/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Rheumatoid Factor Positive Other Serious 8/10/2002 43 Female 11/23/2006 Other Health Professional Korea, Republic Of
Primary
Secondary
Concomitant
Lip And/or Oral Cavity Cancer Other Serious 1/1/2000 55 Female 12/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/3/2005 39 Female 128 lb 12/12/2006 Physician United Kingdom
Primary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 1/1/2000 60 Female 12/12/2006
Primary
Secondary
Venoocclusive Liver Disease Hospitalization 11/22/2005 44 Female 124 lb 12/5/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 5/21/2006 65 Female 143 lb 12/18/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Other Serious 55 Female 12/4/2006 Other Health Professional United States
Primary
Secondary
Lip And/or Oral Cavity Cancer Other Serious 1/1/2000 60 Female 1/9/2007 United States
Primary
Secondary
Concomitant
Sepsis Neonatal Other Serious Male 3 lb 1/19/2007 Physician Austria
Primary
Concomitant
Myeloid Leukaemia Hospitalization 56 Female 6/6/2003 Physician United States
Primary
Secondary
Endometrial Dysplasia Required Intervention 37 Female 5/6/2004 Physician
Primary
Concomitant
Tooth Extraction Other Serious 65 Female 3/25/2007 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 63 Female 3/25/2007 Other Health Professional United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 32 Female 3/28/2007 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 54 Female 4/21/2007 Physician Brazil
Primary
Concomitant
Tooth Extraction Other Serious 10/3/2005 39 Female 128 lb 5/12/2007 Physician United Kingdom
Primary
Concomitant
Neuropathy Peripheral Other Serious 12/1/1996 59 Female 6/6/2007 Other Health Professional Italy
Primary
Secondary
Neuropathy Peripheral Other Serious 12/1/1996 59 Female 7/6/2007 Other Health Professional Italy
Primary
Secondary
Tongue Carcinoma Stage I Other Serious 1/1/2000 60 Female 7/9/2007 Physician United States
Primary
Secondary
Weight Decreased Other Serious 51 Female 9/7/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Nuclear Magnetic Resonance Imaging Brain Abnormal Other Serious 60 Female 10/10/2007 Other Health Professional United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 58 Female 11/7/2007 Other Health Professional Japan
Primary
Concomitant
Hypertension Other Serious 9/20/2007 42 Female 168 lb 11/12/2007 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 58 Female 11/27/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Polyneuropathy Hospitalization 10/21/2007 Female 154 lb 12/11/2007 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 61 Female 1/16/2008
Primary
Concomitant
Acute Myeloid Leukaemia Other Serious 12/27/2005 42 Female 2/15/2008 Greece
Primary
Secondary
Concomitant
Weight Decreased Other Serious 51 Female 3/21/2008 Other Health Professional United Kingdom
Primary
Interacting
Pancytopenia Hospitalization 12/21/2007 Female 3/21/2008 Physician Australia
Primary
Secondary
Concomitant
Weight Decreased Other Serious 51 Female 4/4/2008 Other Health Professional United Kingdom
Primary
Interacting
Weight Decreased Other Serious 51 Female 4/8/2008 Consumer United States
Primary
Secondary
Weight Decreased Other Serious 51 Female 4/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 12/21/2007 Female 5/2/2008 Physician Australia
Primary
Secondary
Concomitant
Haemangioma Hospitalization 7/27/2007 44 Female 6/3/2008 Other Health Professional Hong Kong
Primary
Secondary
Concomitant
Hypothyroidism Disability 3/11/2008 Female 6/12/2008 Physician France
Primary
Secondary
Left Ventricular Dysfunction Other Serious 5/17/2008 53 Female 130 lb 6/26/2008 Physician United States
Primary
Secondary
Concomitant
Left Ventricular Failure Hospitalization 8/26/1999 Female 7/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 12/21/2007 Female 7/23/2008 Physician Australia
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Hospitalization 5/17/2008 53 Female 130 lb 7/24/2008 Physician United States
Primary
Secondary
Concomitant
Tremor Disability 3/14/2008 Female 7/25/2008 Pharmacist United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/26/1999 Female 8/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 11/15/2007 Female 176 lb 8/11/2008 Physician Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 8/26/1999 Female 8/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Leukopenia Other Serious 12/4/2007 38 Female 8/28/2008 Japan
Primary
Secondary
Concomitant
Left Ventricular Failure Hospitalization 4/1/2008 Female 10/10/2008 Physician Germany
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 42 Female 1/12/2009 Netherlands
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 44 Female 1/14/2009 Netherlands
Primary
Secondary
Concomitant
Carpal Tunnel Syndrome Disability 12/9/2008 Female 1/20/2009 Consumer United Kingdom
Primary
Concomitant
Musculoskeletal Pain Hospitalization 7/13/2007 Female 165 lb 1/23/2009 Physician Germany
Primary
Concomitant
Interacting
Hypertension Other Serious 9/20/2007 42 Female 168 lb 2/12/2009 Physician United States
Primary
Secondary
Concomitant
Myeloid Leukaemia Other Serious 47 Female 2/26/2009
Primary
Secondary
Myalgia 11/5/2007 Female 3/18/2009 Consumer United States
Primary
Concomitant
Polyneuropathy Hospitalization 3/11/2009 58 Female 185 lb 3/23/2009 Physician Denmark
Primary
Secondary
Concomitant
Polyneuropathy Hospitalization 3/11/2009 Female 185 lb 4/16/2009 Physician Denmark
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 9/3/2007 Female 5/8/2009 Physician Belgium
Primary
Secondary
Concomitant
Sudden Death Death 3/23/2009 Female 5/21/2009 Consumer Portugal
Primary
Secondary
Concomitant
Neoplasm Malignant Death 3/3/2003 66 5/27/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Wound Infection Hospitalization 11/21/2007 51 Female 6/24/2009 Physician United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Life Threatening 42 Female 7/13/2009 Other Health Professional United States
Primary
Secondary
Acute Myeloid Leukaemia Life Threatening 68 Female 7/13/2009 Other Health Professional United States
Primary
Secondary
Pneumonitis Other Serious 50 Female 8/10/2009
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 72 8/19/2009 Other Health Professional United States
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 35 8/19/2009 Other Health Professional United States
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 52 8/19/2009 Other Health Professional United States
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 52 8/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 52 Female 8/28/2009 Other Health Professional United States
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 35 9/4/2009 Other Health Professional United States
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 72 9/8/2009 Other Health Professional United States
Primary
Secondary
Pyrexia Hospitalization 7/20/2009 Female 137 lb 9/9/2009 Physician Japan
Primary
Secondary
Concomitant
Sudden Death Death 3/1/2009 Female 9/15/2009 Consumer Portugal
Primary
Secondary
Concomitant
Weight Decreased Other Serious 51 Female 10/1/2009 Other Health Professional United Kingdom
Primary
Interacting
Osteonecrosis Other Serious 51 Female 10/1/2009 United Kingdom
Primary
Interacting
Ruptured Ectopic Pregnancy Hospitalization 10/6/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 1/1/2007 38 Female 10/30/2009 Taiwan, Province Of China
Primary
Secondary
Swelling Other Serious 4/1/2007 37 Female 11/6/2009 Taiwan, Province Of China
Primary
Secondary
Concomitant
Acute Promyelocytic Leukaemia Other Serious 51 Female 11/23/2009 Other Health Professional Japan
Primary
Secondary
Pancytopenia Other Serious 35 Female 12/14/2009 Consumer Japan
Primary
Secondary
Osteonecrosis Disability 1/1/2004 Female 12/28/2009 Other Health Professional Italy
Primary
Concomitant
Osteonecrosis Disability 1/1/2004 Female 1/22/2010 Other Health Professional Italy
Primary
Concomitant
Congestive Cardiomyopathy Other Serious Female 2/15/2010 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 4/12/2000 42 Female 151 lb 2/17/2010 Consumer Canada
Primary
Secondary
T-cell Prolymphocytic Leukaemia Other Serious 45 Female 2/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Leukopenia Other Serious 12/4/2007 38 Female 3/5/2010 Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 9/16/1998 66 Female 3/5/2010 Consumer Canada
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 50 Female 3/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Other Serious 47 Female 3/15/2010
Primary
Secondary
Concomitant
Acute Myelomonocytic Leukaemia Hospitalization 70 Female 3/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 48 Female 3/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Hospitalization 70 Female 3/25/2010 Other Health Professional United States
Primary
Secondary
Acute Myelomonocytic Leukaemia Other Serious 70 Female 3/25/2010 Physician United States
Primary
Secondary
Acute Myelomonocytic Leukaemia Other Serious 70 Female 3/25/2010 Physician United States
Primary
Secondary
Acute Myelomonocytic Leukaemia Other Serious 70 Female 3/25/2010 Physician United States
Primary
Secondary
Weight Decreased Other Serious 1/1/2001 44 Female 134 lb 4/12/2010 Physician United States
Primary
Concomitant
T-cell Prolymphocytic Leukaemia Other Serious 45 Female 4/9/2010 Physician India
Primary
Secondary
Pulmonary Toxicity Hospitalization 7/28/2004 56 Female 154 lb 4/19/2010 Physician United Kingdom
Primary
Secondary
Concomitant
T-cell Prolymphocytic Leukaemia Other Serious 45 Female 4/9/2010 India
Primary
Secondary
Weight Decreased Other Serious 1/1/2001 44 Female 134 lb 5/4/2010 United States
Primary
Concomitant
Alopecia Disability 1/1/2008 39 Female 5/11/2010 Physician France
Primary
Secondary
Concomitant
Left Atrial Dilatation Other Serious 1/1/2009 57 Female 6/2/2010 Other Health Professional Portugal
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 68 Female 5/28/2010 Physician United States
Primary
Concomitant
Sudden Death Hospitalization 1/1/2009 57 Female 123 lb 6/10/2010 Portugal
Primary
Secondary
Concomitant
Alopecia Other Serious Female 7/23/2010 Physician France
Primary
Secondary
Weight Decreased Other Serious Female 8/3/2010 United States
Primary
Concomitant
Weight Decreased Other Serious Female 8/16/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2001 44 Female 134 lb 8/29/2010 United States
Primary
Concomitant
Amenorrhoea Other Serious Female 9/3/2010 Consumer Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 9/7/2010 Physician United States
Primary
Concomitant
Leukopenia Other Serious 12/4/2007 38 Female 9/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Polyneuropathy Hospitalization 10/20/2008 58 Female 185 lb 9/28/2010 Physician Denmark
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 10/11/2010 Other Health Professional United States
Primary
Concomitant
Deafness Neurosensory Disability 8/1/2009 50 Female 172 lb 10/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Deafness Neurosensory Disability 8/1/2009 50 Female 10/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Deafness Neurosensory Disability 8/1/2009 50 Female 10/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Disability 1/1/2010 76 Female 154 lb 10/19/2010 Physician Switzerland
Primary
Secondary
Concomitant
Deafness Neurosensory Disability 8/1/2009 50 Female 172 lb 11/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Deafness Neurosensory Disability 8/1/2009 50 Female 10/26/2010 United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 5/1/2010 62 1/3/2011 Physician Australia
Primary
Concomitant
Obliterative Bronchiolitis Other Serious 41 Male 1/5/2011 Other Health Professional Belgium
Primary
Concomitant
Metastases To Lung Other Serious 41 Male 1/17/2011 Other Health Professional Belgium
Primary
Concomitant
Acute Leukaemia Other Serious 40 Female 2/3/2011 Other Health Professional Korea, Republic Of
Primary
Secondary
Fatigue Hospitalization 78 Female 2/8/2011 Other Health Professional United States
Primary
Concomitant
Angiosarcoma Hospitalization 67 Female 2/25/2011 Physician United Kingdom
Primary
Secondary
Angiosarcoma Other Serious 61 Female 3/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Angiosarcoma Hospitalization 67 Female 3/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Angiosarcoma Hospitalization 67 Female 3/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Angiosarcoma Hospitalization 67 Female 3/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Angiosarcoma Hospitalization 67 Female 3/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Bronchiolitis Other Serious 41 Male 3/30/2011 Other Health Professional Belgium
Primary
Secondary
Obliterative Bronchiolitis Other Serious 41 Male 4/4/2011 Physician Belgium
Primary
Secondary
Cataract Other Serious 6/29/2006 82 Female 4/5/2011 Other Health Professional United States
Primary
Concomitant
Confusional State Hospitalization 60 Female 4/11/2011 Other Health Professional Greece
Primary
Concomitant
Acute Promyelocytic Leukaemia Other Serious 9/1/2009 43 Female 4/29/2011 Physician Turkey
Primary
Secondary
Acute Promyelocytic Leukaemia Other Serious 43 Female 5/2/2011 Other Health Professional Turkey
Primary
Secondary
Bone Lesion Other Serious 31 Female 4/21/2011 Physician Denmark
Primary
Secondary
Concomitant
Lower Limb Fracture Other Serious 6/29/2006 82 Female 5/16/2011 Other Health Professional United States
Primary
Concomitant
Endometrial Hyperplasia Hospitalization 3/14/2011 49 Female 146 lb 5/20/2011 Physician Germany
Primary
Secondary

Drug Data