Cyclophosphamide combined with Sodium Bicarbonate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Other Serious 10/1/2005 59 Male 198 lb 1/24/2006 Pharmacist Spain
Primary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 6/9/2006 Physician United States
Primary
Secondary
Concomitant
Vaginal Exfoliation Hospitalization 5/23/2006 Female 139 lb 7/13/2006 Physician United Kingdom
Primary
Concomitant
Pulmonary Oedema Life Threatening 4/7/2006 Female 116 lb 8/10/2006 Physician United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/29/2006 50 Male 9/18/2006 Physician Israel
Primary
Concomitant
Pollakiuria Disability 8/1/2006 66 Female 3/15/2007 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious Male 217 lb 5/31/2007 Physician Sweden
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 4/18/2007 Male 6/5/2007 Physician Australia
Primary
Concomitant
Weight Increased Other Serious 67 Male 6/11/2007 Consumer United States
Primary
Secondary
Concomitant
Xerosis Hospitalization 11 Male 6/13/2007 Physician United States
Primary
Concomitant
Nephropathy Toxic Other Serious 4/1/2005 13 Male 7/2/2007 Other Health Professional United States
Primary
Secondary
Venoocclusive Liver Disease Hospitalization 10/22/2006 11 Female 75 lb 7/2/2007 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious Male 217 lb 9/6/2007 Consumer Sweden
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 11 Male 10/30/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/28/2007 14 Female 126 lb 11/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 126 lb 11/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 9/28/2007 21 Female 150 lb 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/10/2007 74 Female 12/4/2007 Consumer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 9/28/2007 21 Female 150 lb 12/3/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/10/2007 74 Female 12/17/2007 Consumer United States
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Hospitalization 5/11/2007 Male 205 lb 4/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/19/2008 Lawyer United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/23/2008 Lawyer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 11/1/2007 43 Male 10/7/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 11/1/2007 56 Male 10/7/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 12/1/2007 53 Male 10/7/2008 Physician United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 12/21/2008 4 Male 44 lb 1/7/2009 Physician Germany
Primary
Secondary
Concomitant
Puncture Site Infection Hospitalization 12/21/2008 4 Male 44 lb 1/22/2009 Physician Germany
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 12/21/2008 4 Male 44 lb 2/2/2009 Physician Germany
Primary
Secondary
Concomitant
Methaemoglobinaemia Life Threatening 3/4/2009 39 Female 124 lb 3/17/2009 Pharmacist United States
Primary
Concomitant
Troponin T Increased Other Serious 4/18/2007 Male 3/31/2009 Physician Australia
Primary
Concomitant
Renal Impairment Life Threatening 6/26/2008 49 4/6/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/4/2008 55 Female 4/29/2009 Japan
Primary
Concomitant
Transaminases Increased Hospitalization 12/21/2008 4 Male 44 lb 6/26/2009 Physician Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/8/2009 Female 7/21/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 10/1/2007 Female 7/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/8/2009 Female 7/29/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 10/1/2007 Female 7/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/8/2009 Female 8/5/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 57 Male 8/6/2009
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/8/2009 Female 8/19/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/8/2009 Female 8/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 6/8/2009 Male 164 lb 8/24/2009 Physician Germany
Primary
Concomitant
Thrombocytopenia Hospitalization 12/1/2008 74 Female 12/23/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
No Adverse Event Hospitalization 1/29/2010 59 Male 171 lb 2/15/2010 Pharmacist Spain
Primary
Concomitant
Pyrexia Other Serious 3/22/2009 15 Male 110 lb 2/26/2010 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 1/19/2010 Female 118 lb 3/29/2010 Canada
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 1/23/2010 Female 3/29/2010 Physician France
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/19/2010 37 Female 118 lb 4/1/2010 Canada
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/31/2010 55 Male 5/5/2010 Pharmacist Canada
Primary
Concomitant
Uterine Enlargement Other Serious 32 Female 5/6/2010 Physician Greece
Primary
Secondary
Uterine Enlargement Other Serious 32 Female 5/27/2010 Physician Greece
Primary
Secondary
Uterine Enlargement Other Serious 32 Female 5/28/2010 Physician Greece
Primary
Secondary
Splenomegaly Required Intervention 12/3/2006 9 Female 64 lb 7/23/2010 Physician United States
Primary
Secondary
Concomitant
Ocular Toxicity Hospitalization 6/20/2010 48 Female 161 lb 8/10/2010 Physician France
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 8/18/2010 67 Male 9/22/2010 Physician Germany
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/5/2010 65 Female 206 lb 9/23/2010 Physician United Kingdom
Primary
Concomitant
Subdural Haematoma Hospitalization 8/18/2010 67 Male 190 lb 9/24/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 12/3/2009 35 Female 9/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hepatotoxicity Hospitalization 10/2/2010 26 Male 139 lb 11/30/2010 Physician Malaysia
Primary
Secondary
Concomitant
Renal Failure Other Serious 10/5/2010 10 Female 107 lb 12/10/2010 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 7/1/2009 48 Female 115 lb 1/6/2011 Physician Japan
Primary
Concomitant
Blood Pressure Increased Other Serious 8/9/2009 48 Female 115 lb 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/5/2010 65 Female 206 lb 3/10/2011 Physician United Kingdom
Primary
Concomitant
Delirium Other Serious 6/16/2010 53 Male 154 lb 4/8/2011 Physician Japan
Primary
Concomitant
Renal Failure Acute Other Serious 12/1/2010 71 Female 127 lb 4/19/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 12/1/2010 71 Female 127 lb 4/27/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Pseudomembranous Colitis Hospitalization 6/20/2010 65 Female 91 lb 4/28/2011 Physician Canada
Primary
Secondary
Concomitant
Arthralgia Hospitalization 4/22/2011 27 Female 6/24/2011 Consumer France
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Death 6/13/2011 71 Male 211 lb 6/30/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Erythema Hospitalization 4/22/2011 27 Female 7/12/2011 Physician France
Primary
Secondary
Concomitant
Pseudomembranous Colitis Hospitalization 6/20/2010 65 Female 91 lb 7/13/2011 Physician Canada
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Other Serious 17 Male 7/14/2011 Other Health Professional China
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 43 Male 7/14/2011 Other Health Professional China
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 32 Female 7/14/2011 Other Health Professional China
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 38 Male 7/14/2011 Other Health Professional China
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 18 Male 7/14/2011 Physician China
Primary
Concomitant
Chronic Graft Versus Host Disease Other Serious 32 Male 7/14/2011 Other Health Professional China
Primary
Concomitant
Colitis Other Serious 7/25/2011 67 Male 182 lb 8/5/2011 Physician United States
Primary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 8/8/2011 Physician United States
Primary
Concomitant
Viith Nerve Paralysis Hospitalization 7/23/2011 66 Female 205 lb 8/17/2011 Physician United Kingdom
Primary
Concomitant
Cardiac Failure Death 6/13/2011 71 Male 211 lb 8/19/2011 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 6/13/2011 71 Male 211 lb 8/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 7/25/2011 67 Male 182 lb 8/28/2011 Physician United States
Primary
Concomitant
Bronchitis Other Serious 6/22/2010 56 Female 8/29/2011 Other Health Professional Japan
Primary
Secondary
Colitis Other Serious 7/25/2011 67 Male 182 lb 8/30/2011 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 56 Female 9/2/2011 Other Health Professional Japan
Primary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 9/2/2011 Physician United States
Primary
Concomitant
Metastases To Liver Other Serious 12/1/2009 60 Female 86 lb 9/2/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 12/1/2009 60 Female 86 lb 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 9/12/2011 55 Female 95 lb 9/23/2011 Physician Japan
Primary
Secondary
Concomitant
Myocardial Fibrosis Disability 1/1/2000 11 Male 77 lb 9/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Device Related Sepsis Death 9/12/2011 55 Female 95 lb 9/27/2011 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 9/12/2011 55 Female 95 lb 10/3/2011 Physician Japan
Primary
Secondary
Concomitant
Hypertension Other Serious 6/12/2010 53 Male 154 lb 10/5/2011 Physician Japan
Primary
Concomitant
Tubulointerstitial Nephritis Death 16 Male 10/20/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 10/24/2004 17 Male 10/24/2011 Physician China
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 43 Male 10/24/2011 Other Health Professional China
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 1/8/2008 32 Female 10/24/2011 Other Health Professional China
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 11/29/2006 38 Male 10/24/2011 Physician China
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 1/16/2009 32 Male 10/25/2011 Other Health Professional China
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 4/21/2008 18 Male 10/25/2011 Other Health Professional China
Primary
Concomitant
Hypertension Other Serious 16 Male 10/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 8/23/2011 13 Male 92 lb 11/3/2011 Pharmacist Brazil
Primary
Secondary
Concomitant
Interacting
Blood Glucose Increased Other Serious 2/11/2011 55 Female 123 lb 11/11/2011 Physician Japan
Primary
Concomitant
Pancreatitis Hospitalization 16 Male 11/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 7/6/2011 77 Female 11/18/2011 Physician Australia
Primary
Secondary
Concomitant
Cytolytic Hepatitis Other Serious 1/28/2011 57 Female 132 lb 11/23/2011 Physician France
Primary
Concomitant
Transplant Rejection Hospitalization 8/25/2011 73 Male 11/24/2011 France
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/29/2011 67 Female 11/29/2011 Physician Korea, Republic Of
Primary
Concomitant
Cytolytic Hepatitis Other Serious 1/29/2011 57 Female 132 lb 12/6/2011 Physician France
Primary
Concomitant
Pyrexia Hospitalization 10/25/2010 11 Male 66 lb 12/12/2011 Physician Japan
Primary
Concomitant
Cytolytic Hepatitis Other Serious 1/29/2011 57 Female 132 lb 12/16/2011 Consumer France
Primary
Concomitant
Leukopenia Other Serious 2/26/2007 68 Male 173 lb 12/20/2011 Consumer United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 8/13/2009 48 Female 133 lb 12/20/2011 Physician United States
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Other Serious 2/26/2007 68 Male 173 lb 12/27/2011 Consumer United States
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Other Serious 2/26/2007 68 Male 173 lb 12/29/2011 Physician United States
Primary
Secondary
Concomitant
Hyponatraemia Death 50 Male 1/4/2012 Other Health Professional Morocco
Primary
Secondary
Concomitant
Infection Hospitalization 1/29/2009 3 Female 35 lb 2/10/2012 Physician Japan
Primary
Concomitant
Aids Encephalopathy Other Serious 5/29/2011 67 Female 3/8/2012 Physician Korea, Republic Of
Primary
Concomitant
Nausea Other Serious 6/12/2010 53 Male 154 lb 3/15/2012 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 10/25/2010 11 Male 66 lb 3/26/2012 Physician Japan
Primary
Concomitant
Skin Infection Other Serious 4/2/2011 27 Female 112 lb 4/9/2012 Physician Japan
Primary
Concomitant
Bronchopneumonia Hospitalization 2/14/2012 Male 5/15/2012 Physician Germany
Primary
Secondary
Concomitant
Wound Dehiscence Death 1/20/2011 65 Male 150 lb 5/23/2012 Physician France
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 4/2/2011 27 Female 112 lb 5/30/2012 Physician Japan
Primary
Concomitant
Dry Eye Other Serious 6/12/2010 53 Male 154 lb 5/30/2012 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Death 2/11/2011 55 Female 123 lb 6/8/2012 Physician Japan
Primary
Secondary
Concomitant
Haemolytic Uraemic Syndrome Death 1/29/2009 3 Female 35 lb 7/5/2012 Physician Japan
Primary
Concomitant
Hyperphosphataemia Other Serious 51 Male 7/30/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Graft Versus Host Disease In Skin Death 2/11/2011 55 Female 123 lb 7/31/2012 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 3/29/2012 70 Female 194 lb 8/1/2012 Physician United States
Primary
Secondary
Concomitant
Pulmonary Cavitation Hospitalization 7/5/2012 51 Male 144 lb 8/10/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Bk Virus Infection Other Serious 4/2/2011 27 Female 112 lb 8/14/2012 Physician Japan
Primary
Secondary
Concomitant
Puncture Site Infection Hospitalization 12/5/2008 8/15/2012 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 7/27/2012 8/15/2012 Physician France
Primary
Secondary
Concomitant
Pseudomonas Infection Hospitalization 7/5/2012 51 Male 144 lb 8/16/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 3/29/2012 70 Female 194 lb 8/16/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Metabolic Acidosis Death 51 Male 8/16/2012 Physician Japan
Primary
Secondary
Hypophosphataemia Other Serious 51 Male 127 lb 8/22/2012 Physician Japan
Primary
Secondary
Circulatory Collapse Death 5/30/2012 54 Female 139 lb 8/24/2012 Physician Bulgaria
Primary
Secondary
Concomitant
No Adverse Event Hospitalization 1/29/2010 59 Male 171 lb 10/22/2012 Other Health Professional Es
Primary
Concomitant
Viith Nerve Paralysis Hospitalization 7/23/2011 66 Female 205 lb 10/19/2012 Physician Gb
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 2/11/2011 55 Female 123 lb 9/6/2012 Physician Jp
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 4/23/2012 4 Female 11/19/2012 Physician Us
Primary
Secondary
Concomitant
Circulatory Collapse Death 6/5/2012 55 Female 139 lb 10/11/2012 Physician Bg
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 51 Male 127 lb 9/21/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 12/9/2011 57 Female 9/21/2012 Consumer Cn
Primary
Concomitant
Urinary Tract Infection Other Serious 12/21/2011 70 Female 198 lb 10/11/2012 Physician Us
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 12/21/2011 70 Female 194 lb 10/3/2012 Other Health Professional Us
Primary
Secondary
Concomitant

Drug Data