Cyclophosphamide combined with Rituximab (Rituximab)

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Increased Hospitalization 12/12/2005 51 Male 238 lb 2/3/2006 Physician United States
Primary
Secondary
Concomitant
Psychomotor Skills Impaired Other Serious 64 Male 2/2/2006
Primary
Secondary
Respiratory Failure Hospitalization 52 Male 2/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Other Serious 3/1/2004 66 Male 2/6/2006 Physician United States
Primary
Secondary
Concomitant
Transplant Life Threatening 7/2/2005 59 Male 139 lb 2/22/2006 Physician France
Primary
Secondary
Concomitant
Peritoneal Carcinoma Life Threatening 7/2/2005 59 Male 139 lb 3/6/2006 Physician France
Primary
Secondary
Concomitant
Carditis Death 24 Female 3/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Therapy Non-responder Hospitalization 52 Male 3/10/2006 Physician United Kingdom
Primary
Secondary
Metastases To Peritoneum Life Threatening 7/2/2005 59 Male 139 lb 3/16/2006 Physician France
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 66 Male 3/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Therapy Non-responder Other Serious 66 Male 4/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 7/26/2005 66 Male 203 lb 5/3/2006 Physician Hungary
Primary
Secondary
Concomitant
Sepsis Other Serious 75 Male 5/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Therapy Non-responder Hospitalization 66 Male 5/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 12/15/2005 26 Male 5/11/2006 Physician United States
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 66 Male 5/26/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/9/2006 39 Male 5/24/2006 Physician New Zealand
Primary
Concomitant
Thrombocytopenia Hospitalization 9/20/2003 62 Male 6/16/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/18/2003 62 Male 175 lb 6/16/2006 United States
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Recurrent Hospitalization 45 Female 7/23/2006 United States
Primary
Secondary
Cerebral Atrophy Hospitalization 11/9/2004 68 Female 106 lb 8/7/2006 Physician France
Primary
Secondary
Therapy Non-responder Death 7/1/2005 66 Male 8/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Other Serious 9/1/2003 Female 9/8/2006
Primary
Secondary
White Blood Cell Count Decreased Other Serious 65 Male 9/15/2006 Japan
Primary
Secondary
Tachypnoea Hospitalization 80 Male 10/5/2006 Physician Israel
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Life Threatening 62 Female 10/9/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 62 Female 10/20/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 10/3/2006 86 Female 141 lb 10/23/2006 Physician Puerto Rico
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 6/21/2004 60 Male 187 lb 10/26/2006 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 11/3/2006 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 11/3/2006 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 11/3/2006 Physician Japan
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 51 Female 11/6/2006 Physician Japan
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Life Threatening 62 Female 11/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 7/1/2006 69 Male 220 lb 11/14/2006 Physician France
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 53 Male 11/22/2006 Physician Australia
Primary
Secondary
Refractory Anaemia With An Excess Of Blasts Other Serious 66 Female 11/22/2006 Physician Australia
Primary
Secondary
Myelodysplastic Syndrome Other Serious 69 Male 11/22/2006 Physician Australia
Primary
Secondary
Carditis Death 24 Female 12/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Systemic Candida Death 1 Male 2/6/2007 Physician Taiwan, Province Of China
Primary
Secondary
Septic Shock Other Serious 73 Female 4/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Death 47 Male 5/20/2007 Physician Japan
Primary
Concomitant
Hypoglycaemia Hospitalization 10/1/2007 63 Male 10/15/2007 Other Health Professional United States
Primary
Secondary
Septic Shock Hospitalization 73 Female 11/6/2007 Physician United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/21/2008 United Kingdom
Primary
Secondary
Toxic Skin Eruption Hospitalization 1/2/2008 72 Male 2/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Weight Decreased Death 45 Female 3/13/2008 United Kingdom
Primary
Secondary
Weight Decreased Death 45 Female 4/4/2008 United Kingdom
Primary
Secondary
Neutropenia Hospitalization 8/7/2008 44 Male 148 lb 8/21/2008 Belgium
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 8/8/2008 68 Female 136 lb 9/11/2008 Physician United States
Primary
Secondary
Sepsis Hospitalization 21 Female 10/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Pyrexia Hospitalization 9/7/2008 54 Female 10/9/2008 France
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 45 Female 10/31/2008 United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 49 Male 8/7/2008 Japan
Primary
Secondary
Concomitant
Respiratory Alkalosis Death 69 Male 12/12/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 11/13/2008 62 Male 12/22/2008 Japan
Primary
Concomitant
Loss Of Consciousness Life Threatening 11/13/2008 62 Male 12/23/2008 Physician Japan
Primary
Concomitant
Viral Haemorrhagic Cystitis Hospitalization 48 Female 1/14/2009 Physician Japan
Primary
Secondary
Urinary Tract Infection Other Serious 5/15/2008 53 Female 1/19/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/7/2009 81 Male 1/15/2009 Australia
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 5/15/2008 53 Female 1/15/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/7/2009 81 Male 1/19/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Thrombocytopenia Death 56 Male 1/27/2009 France
Primary
Secondary
Concomitant
Varicella Other Serious 2/1/2008 38 Male 1/29/2009 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Death 56 Male 1/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/28/2009 81 Male 2/3/2009 Australia
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/7/2009 81 Male 2/4/2009 Australia
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/7/2009 81 Male 2/3/2009 Australia
Primary
Secondary
Concomitant
Cytogenetic Abnormality Other Serious 2/1/2007 Male 2/6/2009 Other Health Professional Japan
Primary
Secondary
Acute Myeloid Leukaemia Other Serious Female 2/6/2009 Other Health Professional Japan
Primary
Secondary
Varicella Other Serious 2/1/2008 39 Male 2/9/2009 France
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 2/4/2008 65 Female 2/9/2009 France
Primary
Secondary
Catheter Sepsis Hospitalization 11/17/2007 56 Male 179 lb 2/17/2009 Physician France
Primary
Secondary
No Therapeutic Response Other Serious 5/1/2007 60 Male 2/19/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 63 Male 2/19/2009 Other Health Professional Italy
Primary
Secondary
Unevaluable Event Hospitalization 9/1/2008 58 Male 137 lb 3/2/2009 Physician France
Primary
Secondary
Graft Versus Host Disease Hospitalization 2/1/2009 60 Male 3/11/2009 Spain
Primary
Secondary
Concomitant
Tachypnoea Other Serious 45 Female 3/11/2009 Physician Taiwan, Province Of China
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Hospitalization 45 Female 3/11/2009 Physician Taiwan, Province Of China
Primary
Secondary
Septic Shock Death 47 Female 3/24/2009 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 72 Female 4/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhagic Stroke Death 56 Male 3/26/2009 France
Primary
Secondary
Concomitant
Blood Stem Cell Harvest Failure Other Serious 53 Male 4/24/2009 United Kingdom
Primary
Secondary
Concomitant
Blood Stem Cell Harvest Failure Other Serious 60 Female 4/24/2009 United Kingdom
Primary
Secondary
Concomitant
Blood Stem Cell Harvest Failure Other Serious 51 Male 4/24/2009 United Kingdom
Primary
Secondary
Concomitant
Blood Stem Cell Harvest Failure Other Serious 45 Male 4/24/2009 United Kingdom
Primary
Secondary
Concomitant
Blood Stem Cell Harvest Failure Other Serious 55 Male 4/24/2009 United Kingdom
Primary
Secondary
Concomitant
No Therapeutic Response Other Serious 5/1/2007 60 Male 4/28/2009 Physician Japan
Primary
Concomitant
Off Label Use Other Serious 55 Male 4/28/2009 United Kingdom
Primary
Secondary
Concomitant
Off Label Use Other Serious 45 Male 4/28/2009 United Kingdom
Primary
Secondary
Concomitant
Blood Stem Cell Harvest Failure Other Serious 51 Male 4/28/2009 United Kingdom
Primary
Secondary
Concomitant
Off Label Use Other Serious 60 Female 4/28/2009 United Kingdom
Primary
Secondary
Concomitant
Blood Stem Cell Harvest Failure Other Serious 53 Male 4/28/2009 United Kingdom
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 7/1/2008 54 Male 5/15/2009 Korea, Republic Of
Primary
Secondary
Concomitant
Septic Shock Death 67 Female 5/20/2009 Other Health Professional Germany
Primary
Secondary
Therapeutic Response Decreased Other Serious 17 Male 6/9/2009 Physician Japan
Primary
Concomitant
Sepsis Life Threatening 61 Male 6/19/2009 Germany
Primary
Secondary
Septic Shock Death 69 Male 6/22/2009 Physician Czech Republic
Primary
Secondary
Septic Shock Death 69 Male 6/30/2009 Physician Czech Republic
Primary
Secondary
No Therapeutic Response Death 53 Male 7/1/2009 Italy
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 31 Female 8/11/2009 Physician China
Primary
Secondary
Tumour Lysis Syndrome Other Serious 13 Male 8/19/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 59 Female 9/14/2009 Other Health Professional United States
Primary
Secondary
Hypoalbuminaemia Hospitalization 3/15/2008 52 Female 10/12/2009 Physician Taiwan, Province Of China
Primary
Secondary
Tumour Necrosis Other Serious 74 Male 10/16/2009 Physician United States
Primary
Secondary
Hepatitis C Rna Increased 1/24/2009 62 Female 11/5/2009 Other Health Professional Japan
Primary
Concomitant
Pseudomonas Infection Death 79 Male 12/7/2009 Germany
Primary
Secondary
Neurotoxicity Other Serious 11/1/2009 68 Male 12/22/2009 Physician Germany
Primary
Secondary
Interstitial Lung Disease Other Serious 69 Male 12/22/2009 United Kingdom
Primary
Secondary
Urinary Incontinence Other Serious 11/30/2009 69 Male 1/18/2010 Physician Germany
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 1/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 78 Female 1/29/2010 Physician United Kingdom
Primary
Secondary
Concomitant
General Physical Health Deterioration Death 78 Female 1/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Hospitalization 4/2/2009 1 Male 26 lb 2/22/2010 Physician United States
Primary
Concomitant
Renal Impairment Other Serious 17 Male 2/22/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/30/2010 72 Female 2/25/2010 Physician Australia
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Death 12/10/2008 51 Female 3/3/2010 Japan
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 11/30/2009 69 Male 3/8/2010 Physician Germany
Primary
Secondary
Concomitant
Ventricular Dyskinesia Hospitalization 1 Female 6/10/2010 Italy
Primary
Secondary
Splenic Infarction Required Intervention 63 Female 6/17/2010 Physician Turkey
Primary
Secondary
Escherichia Sepsis Other Serious 9/7/2008 54 Female 8/10/2010 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Other Serious 8/12/2010 Physician Korea, Democratic People's Republic Of
Primary
Concomitant
Thrombocytopenia Other Serious Female 8/12/2010 Physician Korea, Democratic People's Republic Of
Primary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 53 Male 9/1/2010 Physician Italy
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious Female 9/7/2010 Australia
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious Female 9/7/2010 Australia
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious Female 9/7/2010 Australia
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious Female 9/7/2010 Australia
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 13 Male 9/7/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Device Related Sepsis Hospitalization 11/17/2007 56 Male 179 lb 9/28/2010 Physician France
Primary
Secondary
Respiratory Moniliasis Hospitalization 1/10/2009 51 Female 9/28/2010 Physician France
Primary
Secondary
Thrombocytopenia Hospitalization 9/1/2008 58 Male 137 lb 9/28/2010 Physician France
Primary
Secondary
Cushing's Syndrome Other Serious 2/1/2010 65 Male 1/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pharyngeal Inflammation Hospitalization 11/13/2010 41 Male 146 lb 2/23/2011 Physician France
Primary
Secondary
Concomitant
Cellulitis Other Serious 66 Female 3/10/2011 Australia
Primary
Concomitant
Chest Pain Other Serious Male 3/11/2011 Physician Denmark
Primary
Secondary
Bacteroides Test Positive Hospitalization 78 Male 3/30/2011 Physician New Zealand
Primary
Secondary
Constipation Other Serious 2/1/2010 65 Male 3/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 7/8/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 24 Male 4/1/2011 Physician United States
Primary
Concomitant
Bk Virus Infection Hospitalization 4 Male 6/2/2011 Physician United States
Primary
Secondary
Concomitant
Disease Recurrence Death 1/1/2010 52 Male 6/24/2011 Physician Turkey
Primary
Secondary
Agranulocytosis Hospitalization 72 Male 7/8/2011 Other Health Professional France
Primary
Secondary
Bronchitis Bacterial Hospitalization 7/27/2011 52 Male 11/2/2011 Other Health Professional Germany
Primary
Concomitant
Presyncope Hospitalization 7/12/2011 19 Female 12/22/2011 Physician Germany
Primary
Secondary
Medical Device Complication Hospitalization 10/23/2011 62 Male 238 lb 1/27/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Other Serious 38 Female 2/1/2012 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Decreased Hospitalization 6/21/2011 75 Female 3/2/2012 Physician United Kingdom
Primary
Secondary
Red Blood Cell Count Decreased Hospitalization 6/21/2011 75 Female 3/16/2012 Physician Denmark
Primary
Secondary

Drug Data