Cyclophosphamide combined with Rituxan

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Other Serious 11/11/2004 76 Female 1/3/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 1/19/2005 25 Male 1/3/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/7/2004 62 Male 1/5/2006 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/18/2001 53 Male 95 lb 1/9/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/19/2005 78 Female 191 lb 1/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Required Intervention 72 Male 1/13/2006 Japan
Primary
Secondary
Pleural Effusion Other Serious 53 Male 1/17/2006 Japan
Primary
Concomitant
Neutropenia Hospitalization 10/12/2005 57 Male 151 lb 10/28/2005 Pharmacist United States
Primary
Secondary
Pneumonia Cytomegaloviral Life Threatening 7/21/2004 82 Male 1/23/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 37 Female 1/24/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Death 6/19/2002 61 Female 1/30/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatic Failure Death 12/5/2003 61 Male 2/1/2006 Physician Japan
Primary
Concomitant
Syncope Hospitalization 2/12/2006 63 Male 229 lb 2/15/2006 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 3/27/2005 67 Male 2/17/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2004 63 Female 112 lb 3/2/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Disability 9/10/2004 71 Female 117 lb 3/1/2006 Physician Japan
Primary
Secondary
Concomitant
Prostration Hospitalization 12/1/2005 Male 168 lb 3/9/2006 Physician Portugal
Primary
Secondary
Concomitant
Liver Disorder Other Serious 3/1/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/17/2005 64 Male 119 lb 3/3/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/10/2004 68 Male 152 lb 3/7/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/4/2004 74 Female 115 lb 3/7/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/13/2004 67 Female 117 lb 3/7/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 8/13/2005 75 Male 3/10/2006 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/6/2004 57 Male 3/17/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/6/2005 83 Female 99 lb 3/17/2006 Physician Japan
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 12/12/2004 41 Male 82 lb 3/15/2006 Physician Japan
Primary
Concomitant
Oedema Peripheral Life Threatening 1/6/2006 77 Male 110 lb 3/22/2006 Physician Japan
Primary
Concomitant
Radial Nerve Lesion Other Serious 3/1/2006 65 Male 3/30/2006 Physician Canada
Primary
Concomitant
Pneumonia Respiratory Syncytial Viral Death 21 Male 4/3/2006 Other Health Professional United States
Primary
Concomitant
Pneumonia Death 8/8/2005 78 Male 108 lb 4/11/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2005 49 Male 215 lb 4/14/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 2/12/2006 77 Male 4/13/2006 Physician United States
Primary
Secondary
Concomitant
Pneumonia Death 2/13/2004 63 Male 4/14/2006 Physician Japan
Primary
Secondary
Concomitant
Nerve Compression Other Serious 3/1/2006 65 Male 4/14/2006 Physician Canada
Primary
Concomitant
Viral Infection Hospitalization 12/12/2004 41 4/14/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/28/2005 53 Male 229 lb 4/18/2006 Other Health Professional United States
Primary
Secondary
Thrombocytopenia Hospitalization 1/1/2006 77 Male 4/18/2006 Physician United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 12/26/2004 89 Male 4/19/2006 Physician Japan
Primary
Secondary
Myeloid Leukaemia Other Serious 11/4/2004 78 Male 121 lb 4/20/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2004 63 Female 112 lb 4/24/2006 Physician Japan
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 4/18/2006 79 Male 5/2/2006 Pharmacist Australia
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/12/2004 41 4/24/2006 Physician Japan
Primary
Secondary
Concomitant
Prostration Hospitalization 12/1/2005 Male 168 lb 5/9/2006 Physician Portugal
Primary
Secondary
Concomitant
Pyrexia Other Serious 11/26/2005 53 Male 229 lb 5/3/2006 Other Health Professional United States
Primary
Secondary
Skin Infection Hospitalization 4/1/2006 79 Male 5/12/2006 Pharmacist Australia
Primary
Concomitant
Pyrexia Hospitalization 1/1/2006 Male 146 lb 5/15/2006 Physician Canada
Primary
Concomitant
Myocardial Fibrosis Other Serious 55 Male 5/11/2006 Physician Japan
Primary
Concomitant
Myocardial Fibrosis Other Serious 65 Male 5/11/2006 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 4/8/2006 45 Male 215 lb 5/16/2006 Other Health Professional United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 12/12/2004 41 Male 82 lb 5/12/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/6/2005 83 Female 99 lb 5/24/2006 Physician Japan
Primary
Secondary
Concomitant
Coronary Artery Surgery Hospitalization 4/26/2005 69 Male 4/28/2006 Other Health Professional United States
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Hospitalization 7/16/2005 52 Male 5/25/2006 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2005 49 Male 215 lb 6/5/2006 Physician United States
Primary
Concomitant
Nausea Death 4/26/2006 39 Female 6/2/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 7/16/2004 86 Male 99 lb 5/31/2006 Physician Japan
Primary
Secondary
Hepatitis B Death Unknown 6/5/2006 Physician Japan
Primary
Secondary
Skin Infection Hospitalization 4/1/2006 79 Male 6/13/2006 Other Health Professional Australia
Primary
Concomitant
Pyrexia Hospitalization 1/1/2006 Male 146 lb 6/13/2006 Physician Canada
Primary
Concomitant
Organ Failure Death 5/22/2006 43 Female 5/24/2006 Pharmacist United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 4/21/2004 37 Male 6/15/2006 Physician Japan
Primary
Secondary
Concomitant
Oral Candidiasis Hospitalization 7/18/2003 62 Male 175 lb 6/20/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/18/2002 63 Female 143 lb 6/20/2006 Physician Japan
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2005 49 Male 215 lb 6/26/2006 Physician United States
Primary
Concomitant
Neuropathy Peripheral Hospitalization Male 6/28/2006 Physician Japan
Primary
Concomitant
Blood Urine Present Other Serious 83 Male 6/30/2006 Physician United States
Primary
Concomitant
Hepatitis Fulminant Death 8/8/2005 61 Male 7/7/2006 Physician Japan
Primary
Secondary
Thrombocytopenia Other Serious 8/10/2005 65 Female 279 lb 6/14/2006 Physician United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 7/15/2006 65 Male 176 lb 7/27/2006 Physician United States
Primary
Secondary
Concomitant
Visual Disturbance Hospitalization 6/30/2006 64 Male 7/28/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/30/2005 75 Male 7/28/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/11/2006 Female 7/31/2006 Physician Japan
Primary
Concomitant
Rash Pustular 5/21/2002 Female 122 lb 8/8/2006 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Death 6/30/2005 79 Male 8/2/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 8/8/2005 78 Male 108 lb 8/7/2006 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 2/23/2006 Female 146 lb 8/15/2006 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 64 Male 8/9/2006 Physician United States
Primary
Secondary
Pancytopenia Other Serious 75 Female 8/10/2006 Physician United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 80 Male 8/10/2006 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 2/23/2006 Female 146 lb 8/18/2006 Physician United States
Primary
Secondary
Concomitant
Therapy Non-responder Death Female 143 lb 8/23/2006 Pharmacist United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 4/6/2005 83 Female 99 lb 8/22/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/18/2006 61 Female 8/24/2006 Physician Japan
Primary
Secondary
Concomitant
Pemphigoid Required Intervention 12/14/2004 65 Male 140 lb 6/6/2006 Pharmacist United States
Primary
Concomitant
Rash Hospitalization 9/16/2005 55 Male 6/6/2006 Pharmacist United States
Primary
Concomitant
Infusion Related Reaction Other Serious 40 Male 6/6/2006 Other Health Professional United States
Primary
Secondary
Hypertension Hospitalization 67 Female 6/6/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/15/2006 61 Female 6/6/2006 Other Health Professional United States
Primary
Concomitant
Diffuse Large B-cell Lymphoma Other Serious 9/1/2005 66 Male 6/6/2006 Consumer United States
Primary
Concomitant
Hypoaesthesia Facial Hospitalization 45 Female 6/6/2006 Pharmacist United States
Primary
Concomitant
Lung Infiltration Hospitalization 4/11/2006 80 Male 208 lb 6/6/2006 Physician United States
Primary
Concomitant
Lung Infiltration Required Intervention 3/16/2006 32 Male 230 lb 6/6/2006 Physician United States
Primary
Concomitant
Lung Infiltration Other Serious 63 6/6/2006 Physician United States
Primary
Concomitant
Chest X-ray Abnormal Hospitalization 10/1/2005 62 Male 6/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pneumonitis Other Serious 53 Male 6/6/2006 Pharmacist United States
Primary
Concomitant
Skin Disorder Hospitalization Female 6/6/2006 Physician United States
Primary
Concomitant
Tumour Lysis Syndrome Death 9/18/2005 60 Male 9/5/2006 Physician Japan
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Disability 7/10/2005 42 Female 109 lb 9/5/2006 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 62 Female 9/8/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 3/20/2006 70 Female 108 lb 9/11/2006 Physician Japan
Primary
Secondary
Concomitant
Therapy Non-responder Required Intervention 1/1/2006 63 Male 9/12/2006 Physician United States
Primary
Concomitant
Rhinitis Hospitalization 4/3/2006 84 Female 9/14/2006 Physician Japan
Primary
Secondary
Concomitant
Myocardial Fibrosis Other Serious 55 Male 9/15/2006 Physician Japan
Primary
Concomitant
Myeloid Leukaemia Other Serious 11/4/2004 78 Male 121 lb 9/18/2006 Physician Japan
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 6/30/2006 64 Female 9/19/2006 Physician Japan
Primary
Concomitant
Pericardial Effusion Hospitalization 7/27/2006 64 Unknown 9/19/2006 Other Health Professional Japan
Primary
Secondary
Tumour Lysis Syndrome Hospitalization 5/22/2006 70 Male 198 lb 9/14/2006 United States
Primary
Secondary
Concomitant
Mouth Haemorrhage Death 8/8/2005 61 Male 9/21/2006 Physician Japan
Primary
Secondary
Sepsis Life Threatening 2/11/2005 37 Female 112 lb 10/2/2006 Physician United States
Primary
Concomitant
Sepsis Death 2/1/2005 37 Female 112 lb 10/3/2006 Physician United States
Primary
Concomitant
Oesophageal Ulcer Hospitalization 7/1/2004 75 Female 10/5/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 64 Female 10/9/2006 Physician Japan
Primary
Secondary
Concomitant
Infection Death Female 9/29/2006 Physician Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/23/2006 Female 146 lb 10/16/2006 Physician United States
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 7/27/2006 65 Female 10/10/2006 Physician Japan
Primary
Secondary
Pulmonary Toxicity Death Female 10/18/2006 Physician United States
Primary
Concomitant
Oesophageal Ulcer Hospitalization 7/1/2004 75 Female 10/23/2006 Physician Japan
Primary
Secondary
Thoracic Vertebral Fracture Hospitalization 9/30/2006 50 Female 200 lb 10/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Aortic Thrombosis Hospitalization 10/12/2006 74 Male 156 lb 11/3/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/1/2006 43 Female 10/31/2006 Physician United States
Primary
Concomitant
Secondary Immunodeficiency Death 45 11/1/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/30/2006 63 Male 229 lb 11/3/2006 Other Health Professional United States
Primary
Secondary
Staphylococcal Infection Other Serious 11/3/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/6/2003 64 Female 220 lb 10/9/2006 Physician United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 79 Female 11/7/2006 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 11/1/2006 53 Male 143 lb 11/14/2006 Physician United States
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Death 9/1/2005 62 Male 11/17/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 64 Female 11/28/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/23/2006 68 Male 195 lb 11/30/2006 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 11/1/2006 Female 12/11/2006 Physician United States
Primary
Concomitant
Condition Aggravated Hospitalization 11/23/2006 Male 12/1/2006 United States
Primary
Concomitant
Sepsis Life Threatening 2/11/2005 37 Female 112 lb 12/1/2006 Physician United States
Primary
Concomitant
Acute Respiratory Failure Other Serious 12/4/2006 United States
Primary
Secondary
Condition Aggravated Hospitalization 11/23/2006 72 Male 12/4/2006 United States
Primary
Concomitant
Systemic Lupus Erythematosus Life Threatening 5/6/2006 33 Female 12/5/2006 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Hospitalization 9/30/2006 50 Female 200 lb 12/6/2006 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 10/30/2006 63 Male 229 lb 12/7/2006 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 2/6/2006 62 Female 12/21/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 64 Female 12/15/2006 Other Health Professional Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 65 Male 12/15/2006 Other Health Professional Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 72 Female 12/15/2006 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 65 Female 12/15/2006 Other Health Professional Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 66 Male 12/15/2006 Other Health Professional Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening 55 Female 12/15/2006 Physician Japan
Primary
Concomitant
Tachycardia Hospitalization 12/5/2006 83 Female 136 lb 12/19/2006 Physician United States
Primary
Concomitant
Blood Amylase Increased Other Serious 10/2/2006 64 Female 99 lb 12/21/2006 Physician Japan
Primary
Concomitant
Visual Disturbance Other Serious 65 Female 12/21/2006 Physician Canada
Primary
Concomitant
Portal Vein Thrombosis Hospitalization 15 Female 66 lb 12/22/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/2/2006 52 Male 12/27/2006 Physician United States
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 12/10/2006 31 Male 12/29/2006 Canada
Primary
Concomitant

Drug Data