Cyclophosphamide combined with Phenytoin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Graft Versus Host Disease Hospitalization 8/3/2003 28 Male 4/27/2006 Japan
Primary
Concomitant
Graft Versus Host Disease Death 3/28/2003 31 Male 4/27/2006 Japan
Primary
Concomitant
Graft Versus Host Disease Hospitalization 3/14/2003 32 Male 4/27/2006 Japan
Primary
Concomitant
Vaginal Cellulitis Required Intervention 11/17/2006 26 Female 1/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Stem Cell Transplant Death 12/28/2006 44 Male 3/2/2007 Japan
Primary
Concomitant
Acute Graft Versus Host Disease Hospitalization 10/20/2006 46 Male 3/26/2007 Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 11/10/2006 45 Female 4/4/2007 Japan
Primary
Secondary
Concomitant
Varicella Hospitalization 12/20/2006 52 Male 4/19/2007 Japan
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 4/24/1998 16 Male 1/9/2007 Consumer United States
Primary
Concomitant
Vomiting Death 12/20/2006 52 Male 5/7/2007 Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Death 4/29/2007 21 Female 6/14/2007 Japan
Primary
Concomitant
Thrombotic Microangiopathy Life Threatening 3/5/2007 48 Female 6/14/2007 Japan
Primary
Secondary
Concomitant
Vomiting Death 12/20/2006 52 Male 6/20/2007 Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 3/5/2007 48 Female 7/13/2007 Japan
Primary
Secondary
Concomitant
Vomiting Death 5/5/2007 21 Female 9/4/2007 Other Health Professional Japan
Primary
Concomitant
Vertigo Life Threatening 3/5/2007 48 Female 9/18/2007 Japan
Primary
Secondary
Concomitant
Drug Ineffective Life Threatening 46 Male 10/2/2007 Physician Czech Republic
Primary
Concomitant
Vomiting Life Threatening 4/19/2007 18 Female 11/16/2007 Japan
Primary
Concomitant
Vomiting Other Serious 7/20/2007 52 Female 1/3/2008 Japan
Primary
Concomitant
Venoocclusive Liver Disease Death Male 1/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Death 6 Male 3/10/2008
Primary
Secondary
Concomitant
Vomiting Life Threatening 4/19/2007 16 Female 3/6/2008 Japan
Primary
Concomitant
Viraemia Other Serious 5/23/2007 31 Male 3/6/2008 Japan
Primary
Secondary
Concomitant
Weight Increased Life Threatening 2/6/2007 55 Female 4/30/2008 Japan
Primary
Concomitant
Tumour Flare Life Threatening 10/30/2007 34 Male 5/15/2008 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 2/6/2007 55 Female 5/15/2008 Japan
Primary
Concomitant
Vomiting Life Threatening 10/21/2007 42 Male 6/6/2008 Japan
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 7/1/2007 50 Male 6/19/2008 Japan
Primary
Concomitant
Septic Shock Death 1/15/2007 44 Male 6/30/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/24/2007 15 Male 7/10/2008 Japan
Primary
Concomitant
Stomatitis Hospitalization 8/31/2007 60 Male 7/10/2008 Japan
Primary
Concomitant
Grand Mal Convulsion Life Threatening 2/17/2007 5 Female 7/16/2008 Japan
Primary
Concomitant
Transplant Rejection 12/27/2006 13 Female 7/18/2008 Japan
Primary
Concomitant
Stomatitis 2/21/2008 6 Female 7/18/2008 Japan
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 8/13/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting 11/30/2007 9 Male 8/14/2008 Other Health Professional Japan
Primary
Concomitant
Stomatitis 5/23/2007 29 Female 8/14/2008 Japan
Primary
Concomitant
Stomatitis Hospitalization 5/27/2007 53 Female 8/22/2008 Japan
Primary
Concomitant
Transplant Failure Life Threatening 5/23/2007 55 Female 9/8/2008 Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 3/14/2007 35 Female 9/10/2008 Japan
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 7/29/2007 28 Male 9/16/2008 Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/23/2007 31 Male 9/16/2008 Japan
Primary
Secondary
Concomitant
Stomatitis Life Threatening 12/27/2006 13 Female 9/23/2008 Japan
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 10/10/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Death 8/30/2006 46 Male 10/13/2008 Japan
Primary
Concomitant
T-cell Lymphoma Recurrent 1/21/2008 33 Male 10/16/2008 Japan
Primary
Concomitant
Liver Function Test Abnormal Death 8/30/2006 46 Male 10/20/2008 Japan
Primary
Concomitant
Vision Blurred Hospitalization 12/14/2007 Male 52 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Stomatitis Disability 10/11/2007 58 Female 2/6/2009 Japan
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Death 3/3/2009 Consumer United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 3/3/2009 Consumer United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 3/3/2009 Consumer United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 3/3/2009 Consumer United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 3/2/2009 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 3/2/2009 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 3/2/2009 Physician United States
Primary
Secondary
Concomitant
Pneumonitis Death 3/2/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 4/20/2009 17 Female 8/11/2009 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 4/1/2009 17 Female 9/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/1/2009 17 Female 9/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 4/20/2009 17 Female 9/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Disease Death 56 9/29/2009 United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 68 9/29/2009 United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 4/1/2009 17 Female 10/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/1/2009 17 Female 10/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 4/20/2009 17 Female 11/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization Male 1/11/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Male 1/11/2010 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 4/20/2009 17 Female 3/3/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 15 Male 5/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 7 Male 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ovarian Failure Other Serious 16 Female 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious 9 Male 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 2 Female 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 14 Male 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 9 Female 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 10 Female 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 4 Male 7/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious Female 7/15/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Restrictive Pulmonary Disease Other Serious 9 Male 8/3/2010 Physician United States
Primary
Concomitant
Restrictive Pulmonary Disease Other Serious 11 Male 8/3/2010 Physician United States
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 7 Male 8/3/2010 Physician United States
Primary
Concomitant
Stem Cell Transplant Other Serious 4 Male 8/3/2010 Physician United States
Primary
Concomitant
Herpes Zoster Other Serious 10 Male 8/3/2010 Physician United States
Primary
Concomitant
Ovarian Failure Other Serious 10 Female 8/3/2010 Physician United States
Primary
Concomitant
Sepsis Other Serious 14 Male 8/3/2010 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 9 Female 8/3/2010 Physician United States
Primary
Concomitant
Ovarian Failure Other Serious 16 Female 8/3/2010 Physician United States
Primary
Concomitant
Anaemia Haemolytic Autoimmune Other Serious 10 Male 8/2/2010 Physician United States
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 2 Female 8/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 10 Male 8/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Premature Menopause Other Serious 16 Female 8/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 11 Female 8/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 7 Male 8/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 9 Female 8/4/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 4 Male 8/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 15 Male 8/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/12/2010 Physician Korea, Democratic People's Republic Of
Primary
Concomitant
Thrombocytopenia Other Serious Female 8/12/2010 Physician Korea, Democratic People's Republic Of
Primary
Concomitant
Venoocclusive Disease Other Serious 8/26/2010 Korea, Republic Of
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/1/2000 Female 9/10/2010 Physician Sweden
Primary
Concomitant
Interacting
Swelling Face Other Serious 9/1/2010 5 Female 37 lb 10/8/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vertigo Hospitalization 1/1/2000 Female 10/13/2010 Physician Sweden
Primary
Concomitant
Interacting
Recurrent Cancer Other Serious 10/13/2010 Physician United States
Primary
Concomitant
Stomatitis Other Serious 8 Female 12/6/2010 Physician Thailand
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 8 Male 12/6/2010 Physician Thailand
Primary
Concomitant
Vomiting Other Serious 6 Male 12/6/2010 Physician Thailand
Primary
Concomitant
Enteritis Other Serious 5 Male 12/6/2010 Physician Thailand
Primary
Concomitant
Vomiting Other Serious 17 Female 12/6/2010 Physician Japan
Primary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 1 Male 4/1/2011 United States
Primary
Concomitant
Graft Versus Host Disease Other Serious 2 Female 4/1/2011 Physician United States
Primary
Concomitant
Posterior Reversible Encephalopathy Syndrome Hospitalization 9 Male 6/2/2011 Other Health Professional United States
Primary
Concomitant
Convulsion Hospitalization 16 Female 6/2/2011 Other Health Professional United States
Primary
Concomitant
Toxicity To Various Agents Hospitalization 7 Male 6/2/2011 Other Health Professional United States
Primary
Concomitant
Toxicity To Various Agents Hospitalization 11 Male 6/2/2011 Other Health Professional United States
Primary
Concomitant
Disease Recurrence Other Serious 62 Male 6/21/2011 Other Health Professional Korea, Democratic People's Republic Of
Primary
Secondary
Concomitant
Neoplasm Recurrence Other Serious 43 Male 6/20/2011 Other Health Professional Korea, Democratic People's Republic Of
Primary
Secondary
Concomitant
Recurrent Cancer Other Serious 52 Female 6/21/2011 Other Health Professional Korea, Democratic People's Republic Of
Primary
Secondary
Concomitant
Disease Recurrence Other Serious 33 Male 6/20/2011 Other Health Professional Korea, Democratic People's Republic Of
Primary
Concomitant
Disease Recurrence Other Serious 55 Female 6/20/2011 Other Health Professional Korea, Democratic People's Republic Of
Primary
Secondary
Concomitant
Central Nervous System Lymphoma Death 63 Male 6/16/2011 Other Health Professional Korea, Democratic People's Republic Of
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Hospitalization 59 Male 8/10/2011 Physician Sweden
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 39 Female 8/31/2011 Other Health Professional United States
Primary
Secondary
Lung Consolidation Other Serious 1/19/2011 3 Male 35 lb 9/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 33 lb 9/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Methylobacterium Infection Other Serious 5/22/2011 8 Female 49 lb 9/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Periorbital Oedema Life Threatening 1/27/2011 6 Female 40 lb 10/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cytomegalovirus Infection Life Threatening 1/19/2011 3 Male 35 lb 10/3/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Deep Vein Thrombosis Death 12/7/2010 6 Female 40 lb 10/4/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Convulsion Hospitalization 8/22/2011 62 Male 179 lb 10/5/2011 Physician Netherlands
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2011 8 Female 49 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 35 lb 10/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 1/1/2011 4 Male 37 lb 10/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Methylobacterium Infection Other Serious 8 Female 49 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 6 Female 40 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 10/13/2011 Other Health Professional China
Primary
Secondary
Concomitant
Venoocclusive Disease Death 10/13/2011 Other Health Professional China
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Death 10/13/2011 Other Health Professional China
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 33 lb 10/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haematemesis Other Serious 4 Male 38 lb 10/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2011 8 Female 49 lb 10/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 35 lb 10/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Disorder Other Serious 1/1/2011 8 Female 49 lb 12/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 35 lb 1/6/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 1/24/2011 3 Male 35 lb 1/3/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious Male 2/7/2012 Other Health Professional India
Primary
Concomitant
Central Nervous System Lesion Other Serious 25 Female 10/15/2012 Physician Nl
Primary
Concomitant
Convulsion Other Serious 23 Male 11/2/2012 Other Health Professional Us
Primary
Secondary
Physical Disability Other Serious 36 Female 1/4/2013 Physician Ch
Primary
Secondary
Concomitant

Drug Data