Cyclophosphamide combined with Nplate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Therapeutic Response Decreased Other Serious 10/21/2008 Male 186 lb 11/3/2008 Pharmacist United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 10/21/2008 64 Male 190 lb 11/12/2008 Pharmacist United States
Primary
Concomitant
Death Death 5/1/2009 Female 5/15/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/4/2009 Male 5/19/2009 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 4/7/2009 Male 183 lb 5/20/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/29/2009 Male 5/27/2009 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Female 6/24/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious Female 8/17/2009 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious Female 152 lb 9/16/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious Female 144 lb 10/1/2009 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious Female 12/3/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 11/28/2009 Male 12/23/2009 Physician United States
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 11/28/2009 Male 12/30/2009 Physician United States
Primary
Concomitant
Platelet Count Decreased Hospitalization Male 1/25/2010 Physician United States
Primary
Concomitant
Hodgkin's Disease Refractory Death 5/4/2009 Female 2/10/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious Male 125 lb 2/15/2010 Physician United States
Primary
Concomitant
Platelet Count Increased Other Serious 3/12/2009 Female 2/15/2010 Physician United States
Primary
Concomitant
Platelet Count Increased Other Serious 3/12/2009 Female 2/25/2010 Physician United States
Primary
Concomitant
Death Death 2/11/2010 Female 2/26/2010 Physician United States
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Death Female 3/5/2010 Physician United States
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Hospitalization Female 151 lb 3/11/2010 Physician United States
Primary
Concomitant
Death Death Female 3/18/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious Male 125 lb 3/22/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 9/10/2009 67 Female 4/22/2010 Physician United States
Primary
Concomitant
Mucosal Inflammation Other Serious 6/1/2009 61 Male 153 lb 4/26/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious Female 163 lb 4/30/2010 Physician United States
Primary
Concomitant
Procedural Pain Other Serious 9/5/2009 67 Female 5/5/2010 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Death Female 5/14/2010 Physician United States
Primary
Concomitant
Vomiting Hospitalization 4/1/2010 68 Female 5/26/2010 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 12/24/2009 63 Female 370 lb 6/14/2010 Physician United States
Primary
Concomitant
Vasculitic Rash Other Serious 1/1/2009 53 Male 225 lb 6/21/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/11/2010 69 Male 7/7/2010 Physician United States
Primary
Concomitant
Cardiac Arrest Death 3/23/2010 43 Female 7/7/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/11/2010 69 Male 7/8/2010 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 12/24/2009 63 Female 370 lb 7/13/2010 Physician United States
Primary
Concomitant
Death Death Male 7/13/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Female 7/14/2010 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 12/24/2009 63 Female 370 lb 7/20/2010 Physician United States
Primary
Concomitant
Death Death Male 7/21/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Female 7/21/2010 Physician United States
Primary
Concomitant
Acute Myeloid Leukaemia Death Male 7/23/2010 Physician United States
Primary
Concomitant
Acute Myeloid Leukaemia Death 9/18/2009 72 Male 193 lb 8/4/2010 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Female 8/5/2010 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Female 8/17/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Male 196 lb 8/23/2010 Physician United States
Primary
Concomitant
Pulmonary Embolism Other Serious 12/18/2008 48 Male 215 lb 8/25/2010 Physician United States
Primary
Concomitant
Lymphoma Other Serious 1/1/2010 86 Male 8/26/2010 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 12/24/2009 63 Female 370 lb 8/27/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Male 196 lb 9/3/2010 Physician United States
Primary
Concomitant
Haemorrhage Death 1/1/2010 86 Male 9/8/2010 Physician United States
Primary
Concomitant
Splenectomy Other Serious 6/1/2009 74 Female 9/14/2010 Physician United States
Primary
Concomitant
Splenic Rupture Other Serious Male 9/17/2010 Physician United States
Primary
Concomitant
Pulmonary Embolism Other Serious 12/18/2008 48 Male 215 lb 9/20/2010 Physician United States
Primary
Concomitant
Sepsis Death Male 9/20/2010 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 10/6/2009 58 Female 9/30/2010 Physician United States
Primary
Concomitant
Lymphoma Hospitalization 9/20/2010 53 Female 10/1/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 10/1/2009 50 Male 228 lb 10/5/2010 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization Male 10/7/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 10/21/2008 64 Male 190 lb 10/7/2010 Physician United States
Primary
Concomitant
Vasculitic Rash Other Serious 1/1/2009 53 Male 225 lb 10/8/2010 Physician United States
Primary
Concomitant
Splenomegaly Other Serious 1/1/2010 49 Male 195 lb 10/13/2010 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2009 10/26/2010 Other Health Professional United States
Primary
Concomitant
Platelet Count Decreased Other Serious 8/1/2010 11/8/2010 Physician Germany
Primary
Concomitant
Neutrophilia Other Serious 11/9/2010 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 2/10/2009 11/12/2010 Physician United States
Primary
Concomitant
Death Death 5/10/2010 11/22/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 2/1/2010 11/28/2010 Pharmacist United States
Primary
Concomitant
Death Death 12/3/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 5/1/2010 12/6/2010 Physician United States
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Death 12/10/2010 Physician United States
Primary
Concomitant
Death Death 12/10/2010 Physician Ireland
Primary
Concomitant
Drug Ineffective Life Threatening 2/1/2010 1/5/2011 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 2/1/2010 1/7/2011 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/11/2011 Physician United States
Primary
Concomitant
Fatigue Other Serious 1/14/2011 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 10/14/2010 1/14/2011 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 10/1/2010 1/17/2011 Physician United States
Primary
Concomitant
Acute Myeloid Leukaemia Other Serious 10/1/2010 1/21/2011 Physician United States
Primary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious Male 2/1/2011 Physician United States
Primary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious Male 2/3/2011 Physician United States
Primary
Concomitant
Mitral Valve Incompetence Hospitalization 1/26/2009 43 Female 220 lb 2/3/2011 Physician United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 76 Female 2/3/2011 Physician United States
Primary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious Male 220 lb 2/7/2011 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 10/18/2010 76 Female 2/7/2011 Physician United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 1/26/2009 43 Female 220 lb 2/8/2011 Physician United States
Primary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious Male 220 lb 2/10/2011 Other Health Professional United States
Primary
Concomitant
Essential Thrombocythaemia Other Serious 9/1/2010 76 Female 2/14/2011 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 9/1/2010 76 Female 2/15/2011 Physician United States
Primary
Concomitant
Myalgia Other Serious 9/1/2010 76 Female 2/17/2011 Physician United States
Primary
Concomitant
Neoplasm Malignant Death 11/1/2010 38 Female 162 lb 2/17/2011 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/26/2009 43 Female 220 lb 2/21/2011 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Death 83 Female 144 lb 2/22/2011 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 83 Female 144 lb 2/22/2011 Other Health Professional United States
Primary
Concomitant
Autoimmune Neutropenia Other Serious 69 Male 3/8/2011 Physician United States
Primary
Concomitant
Bone Marrow Reticulin Fibrosis Other Serious 3/12/2010 49 Male 274 lb 3/8/2011 Other Health Professional United States
Primary
Concomitant
Fluid Overload Hospitalization 1/26/2009 43 Female 220 lb 3/11/2011 Physician United States
Primary
Concomitant
Bone Marrow Reticulin Fibrosis Other Serious 3/12/2010 49 Male 274 lb 3/18/2011 Other Health Professional United States
Primary
Concomitant
Large Granular Lymphocytosis Other Serious Female 3/23/2011 Physician United States
Primary
Concomitant
Haemorrhage Intracranial Death 51 Male 4/15/2011 Physician United States
Primary
Concomitant
Large Granular Lymphocytosis Other Serious Female 4/19/2011 Physician United States
Primary
Concomitant
Large Granular Lymphocytosis Other Serious Female 4/22/2011 Physician United States
Primary
Concomitant
Haemorrhage Intracranial Death 51 Male 4/27/2011 Physician United States
Primary
Concomitant
Lymphoma Death 53 Female 4/29/2011 Physician United States
Primary
Concomitant
Pallor Other Serious 1/1/2011 63 Female 212 lb 5/17/2011 Physician United States
Primary
Secondary
Concomitant
Multiple Myeloma Death Male 5/22/2011 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious Female 5/25/2011 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 57 Male 5/25/2011 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious Female 5/25/2011 Physician United States
Primary
Concomitant
Dizziness Postural Hospitalization 1/1/2011 63 Female 196 lb 5/26/2011 Physician United States
Primary
Secondary
Concomitant
Paraesthesia Death 1/1/2010 53 Female 154 lb 6/2/2011 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Death 7/12/2010 77 Male 114 lb 6/15/2011 Other Health Professional United States
Primary
Concomitant
Pancytopenia Other Serious Female 7/15/2011 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 11/1/2010 38 Female 162 lb 7/15/2011 Physician United States
Primary
Concomitant
Contusion Hospitalization Female 7/19/2011 Physician United States
Primary
Secondary
Concomitant
Leukocytosis Other Serious 12/24/2009 63 Female 370 lb 7/21/2011 Other Health Professional United States
Primary
Concomitant
Contusion Hospitalization Female 7/25/2011 Physician United States
Primary
Secondary
Concomitant
Hospitalisation Hospitalization 53 Male 7/28/2011 Physician United States
Primary
Concomitant
Cachexia Hospitalization 76 Female 7/29/2011 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 7/1/2011 Male 176 lb 8/10/2011 Physician Australia
Primary
Concomitant
Thrombocytopenia Other Serious 9/1/2010 76 Female 8/12/2011 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 7/1/2011 Male 176 lb 8/16/2011 Physician Australia
Primary
Concomitant
Anaemia Other Serious 9/1/2010 76 Female 8/22/2011 Other Health Professional United States
Primary
Concomitant
Mouth Haemorrhage Other Serious 7/2/2010 27 Female 172 lb 9/6/2011 Other Health Professional Germany
Primary
Concomitant
Biopsy Bone Marrow Abnormal Other Serious Male 9/9/2011 Physician United States
Primary
Concomitant
Epistaxis Other Serious 7/2/2010 27 Female 172 lb 9/14/2011 Other Health Professional Germany
Primary
Concomitant
Diffuse Large B-cell Lymphoma Recurrent Other Serious Male 9/16/2011 Physician United States
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Hospitalization Male 9/21/2011 Physician United States
Primary
Concomitant
Petechiae Other Serious 7/2/2010 27 Female 172 lb 9/27/2011 Physician Germany
Primary
Concomitant
Pyrexia Other Serious 8/23/2011 49 Male 10/4/2011 Physician United States
Primary
Concomitant
Back Pain Death 2/10/2009 70 Male 10/6/2011 Physician United States
Primary
Concomitant
Bone Marrow Reticulin Fibrosis Other Serious 9/1/2011 68 Female 11/16/2011 Physician United States
Primary
Concomitant
Decreased Appetite Hospitalization 9/1/2011 68 Female 195 lb 11/23/2011 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious Female 143 lb 11/24/2011 Physician United States
Primary
Concomitant
Respiratory Tract Irritation Other Serious 11/23/2011 80 Male 12/5/2011 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious Female 143 lb 12/5/2011 Physician United States
Primary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious Female 12/9/2011 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious Female 143 lb 12/13/2011 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 11/19/2011 80 Male 186 lb 12/14/2011 Physician United States
Primary
Concomitant
Lymphocytosis Other Serious 11/17/2010 84 Female 12/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastric Haemorrhage Other Serious 8/7/2010 71 Female 245 lb 1/12/2012 Physician Greece
Primary
Secondary
Concomitant
Haemorrhage Other Serious 1/1/2011 45 Male 176 lb 1/31/2012 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 10/14/2011 79 Male 176 lb 2/8/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/14/2011 79 Male 176 lb 2/13/2012 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Haemorrhage Death 8/7/2010 Female 245 lb 2/15/2012 Physician Greece
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 2/1/2012 74 Male 6/4/2012 Physician France
Primary
Concomitant
Prostate Cancer Other Serious 74 Male 6/8/2012 Physician France
Primary
Secondary
Prostate Cancer Other Serious Male 6/11/2012 Other Health Professional France
Primary
Secondary
Prostate Cancer Other Serious 74 Male 6/14/2012 Physician France
Primary
Secondary
Respiratory Tract Infection Other Serious 3/1/2012 78 Male 8/7/2012 Consumer Greece
Primary
Concomitant
Drug Ineffective Other Serious Female 8/16/2012 Physician United States
Primary
Concomitant

Drug Data