Cyclophosphamide combined with Mycophenolate Mofetil

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Death 36 Female 1/5/2006 United States
Primary
Secondary
Concomitant
Rales Other Serious 55 Female 2/9/2006 Physician France
Primary
Concomitant
Transaminases Increased Other Serious 19 Female 3/4/2006 Physician Korea, Republic Of
Primary
Concomitant
Respiratory Failure Required Intervention 55 Female 3/15/2006 France
Primary
Concomitant
Vomiting Hospitalization 1/1/2001 42 Male 3/27/2006 Physician United States
Primary
Secondary
Concomitant
Viral Load Increased Other Serious 23 Male 3/31/2006 Other Health Professional Turkey
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 20 Male 4/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 9 Male 41 lb 5/8/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Urine Protein/creatinine Ratio Increased Other Serious Male 6/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Protein/creatinine Ratio Increased Other Serious Male 6/22/2006 Physician United States
Primary
Secondary
Concomitant
Graft Versus Host Disease In Skin Other Serious 61 Female 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 61 Male 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 20 Male 7/6/2006 Physician France
Primary
Secondary
Concomitant
Superficial Spreading Melanoma Stage Ii Other Serious 59 Male 7/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 61 Male 7/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Neoplasm Excision Other Serious 53 Male 7/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 61 Male 7/15/2006 Physician United States
Primary
Secondary
Concomitant
Photosensitivity Reaction Other Serious 53 Male 7/15/2006 Physician United States
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Other Serious 11 Female 7/8/2006 Physician United States
Primary
Secondary
Stem Cell Transplant Other Serious 2 Male 8/7/2006 China
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 7 Female 9/1/2006 Spain
Primary
Concomitant
Systemic Lupus Erythematosus Hospitalization 4/1/2004 54 Female 10/5/2006 Physician United States
Primary
Concomitant
Infection Death Female 9/29/2006 Physician Japan
Primary
Concomitant
Malignant Melanoma Other Serious 59 Male 10/19/2006
Primary
Secondary
Malignant Melanoma Other Serious 53 Male 10/19/2006
Primary
Secondary
Squamous Cell Carcinoma Other Serious 61 Male 10/19/2006
Primary
Secondary
Malignant Melanoma Other Serious 53 Male 10/12/2006 United States
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 31 Female 10/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tuberculosis Other Serious 6/1/1994 38 Male 11/15/2006 Other Health Professional Turkey
Primary
Secondary
Concomitant
Mechanical Ileus Other Serious 11 Male 12/8/2006 Japan
Primary
Concomitant
Urine Output Decreased Other Serious 21 Female 12/16/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Mechanical Ileus Other Serious 11 Male 12/20/2006 Japan
Primary
Concomitant
Sepsis Life Threatening 4/26/2006 18 Male 1/29/2007 France
Primary
Secondary
Concomitant
Vasculitis Death 15 Male 2/6/2007 Physician Canada
Primary
Secondary
Concomitant
Vasculitis Death 15 Male 2/12/2007 Physician Canada
Primary
Secondary
Concomitant
Varicella Hospitalization 61 Female 2/6/2007 Physician Japan
Primary
Concomitant
Somnolence Other Serious 56 Female 3/2/2007
Primary
Secondary
Chronic Graft Versus Host Disease Other Serious 48 Male 3/3/2007 Japan
Primary
Concomitant
Weight Decreased Other Serious 48 Male 3/10/2007 Japan
Primary
Secondary
Concomitant
Congenital Anomaly Congenital Anomaly 21 Female 5/21/2007 Physician France
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 53 Male 5/15/2007 Physician United States
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Death 61 Male 5/15/2007 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 32 Female 5/15/2007 Physician Japan
Primary
Concomitant
Malignant Melanoma Other Serious 53 Male 5/29/2007 Physician United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Death 61 Male 5/29/2007 Physician United States
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 6/1/2001 Male 6/1/2007 Physician United States
Primary
Secondary
Concomitant
Hypogammaglobulinaemia Hospitalization 11/14/2005 Male 6/1/2007 Physician Japan
Primary
Secondary
Concomitant
Sleep Disorder Life Threatening 9/1/2005 48 Female 157 lb 6/4/2007 Other Health Professional France
Primary
Secondary
Neurotoxicity Other Serious 4 6/15/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 6/1/2001 Male 6/1/2007 Physician United States
Primary
Secondary
Concomitant
Mechanical Ileus Life Threatening 8/30/2006 11 Male 7/3/2007 Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 8/30/2006 11 Male 7/5/2007 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/24/2006 23 Male 141 lb 7/24/2007 Consumer United States
Primary
Secondary
Concomitant
Sepsis Other Serious 60 Male 7/10/2007 Physician Japan
Primary
Concomitant
Paraesthesia Other Serious 41 Female 7/8/2007 Physician United States
Primary
Concomitant
Central Nervous System Lymphoma Death 42 Female 7/8/2007 Physician United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 51 Female 8/7/2007 Physician Belgium
Primary
Secondary
Abortion Induced Other Serious 21 Female 9/24/2007
Primary
Secondary
Ventricular Septal Defect Congenital Anomaly 9/24/2007
Primary
Secondary
Erythema Multiforme Death 8/15/2007 Male 292 lb 10/6/2007 Consumer United States
Primary
Concomitant
Neutropenia Other Serious 73 Male 10/15/2007
Primary
Secondary
Concomitant
Erythema Multiforme Death 8/15/2007 Male 292 lb 10/16/2007 Consumer United States
Primary
Concomitant
Muscular Weakness Hospitalization 58 Female 10/23/2007
Primary
Secondary
Concomitant
Vasculitis Other Serious 15 Male 11/5/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Somnolence Other Serious 52 Male 10/31/2007 Physician Japan
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 1/1/2004 Male 11/8/2007 Other Health Professional Portugal
Primary
Secondary
Concomitant
Tracheitis Hospitalization 9/30/2007 16 Female 132 lb 11/12/2007 Physician Argentina
Primary
Secondary
Concomitant
Cerebral Toxoplasmosis Other Serious 52 Male 11/16/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2001 27 Male 11/19/2007 Other Health Professional Brazil
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 65 Female 11/26/2007 Other Health Professional United States
Primary
Secondary
Stem Cell Transplant Other Serious 1/1/2005 65 Female 11/20/2007 Consumer United States
Primary
Secondary
Oral Herpes Other Serious 1/1/2005 65 Female 11/29/2007 Consumer
Primary
Secondary
Systemic Lupus Erythematosus Hospitalization 9/30/2007 16 Female 132 lb 12/20/2007 Physician Argentina
Primary
Secondary
Concomitant
Hypoxia Death 11/2/2007 19 Female 1/7/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 9/30/2007 16 Female 132 lb 1/11/2008 Physician Argentina
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 9/30/2007 16 Female 128 lb 2/4/2008 Physician Argentina
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 9/30/2007 16 Female 128 lb 2/15/2008 Physician Argentina
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 36 Male 2/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 39 Female 3/3/2008
Primary
Secondary
Pulmonary Oedema Other Serious 3/7/2008 Consumer United Kingdom
Primary
Concomitant
Congenital Osteodystrophy Other Serious Female 3/7/2008 Physician Germany
Primary
Secondary
Toxic Encephalopathy Other Serious 1/1/2003 11 Male 3/18/2008 Physician Japan
Primary
Concomitant
Venoocclusive Disease Other Serious 3/13/2008 Physician Germany
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 9/30/2007 16 Female 128 lb 3/20/2008 Physician Argentina
Primary
Secondary
Concomitant
Disease Progression Death 3/21/2008 United Kingdom
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 3/1/2002 16 Female 3/21/2008
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 5 Male 3/24/2008 Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 12 Male 3/27/2008 Japan
Primary
Concomitant
Systemic Lupus Erythematosus Hospitalization 9/30/2007 16 Female 128 lb 3/28/2008 Physician Argentina
Primary
Secondary
Concomitant
Viral Infection Other Serious 3/28/2008 France
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Death 4/2/2008 Germany
Primary
Secondary
Subcutaneous Nodule Other Serious 4 Female 4/3/2008 Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 12 Male 4/7/2008 Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 66 Male 4/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 1/29/2007 Male 176 lb 4/23/2008 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 44 Male 5/9/2008 United States
Primary
Secondary
Transplant Failure Death 6/5/2007 Physician United States
Primary
Secondary
Concomitant
Visual Disturbance Hospitalization 4/25/2008 15 Male 5/19/2008 Consumer United Kingdom
Primary
Concomitant
Systemic Lupus Erythematosus Hospitalization 9/30/2007 Female 106 lb 5/23/2008 Physician Argentina
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 9/30/2007 Female 106 lb 5/30/2008 Physician Argentina
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 64 Female 6/13/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Toxic Encephalopathy Other Serious 9/12/2006 5 Male 6/16/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Scleroderma Other Serious 8/6/2003 68 Female 6/30/2008 Other Health Professional Japan
Primary
Concomitant
Syncope Other Serious 21 Female 7/2/2008 Other Health Professional United States
Primary
Secondary
Retinal Haemorrhage Other Serious 26 Female 7/11/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Tuberculosis Other Serious 31 Female 7/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 26 Female 7/22/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 9/30/2007 Female 106 lb 7/23/2008 Physician Argentina
Primary
Secondary
Concomitant
Hypertrophic Cardiomyopathy 5/15/2008 1 Male 7/17/2008 Other Health Professional Japan
Primary
Concomitant
Vomiting Other Serious 31 Female 8/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Hospitalization 31 Female 8/13/2008 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/2/2007 Female 8/21/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 31 Female 8/21/2008 United Kingdom
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Disability 5/7/2008 80 Female 154 lb 9/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Opportunistic Infection Other Serious 17 Male 9/24/2008 Physician Japan
Primary
Concomitant
Opportunistic Infection Other Serious 17 Male 9/30/2008 Physician Japan
Primary
Concomitant
Neoplasm Malignant Other Serious 7/4/2008 51 Female 10/8/2008 Other Health Professional France
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Hospitalization 31 Female 10/14/2008 Consumer United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Disability 5/7/2008 80 Female 10/6/2008 United Kingdom
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 12 Female 10/20/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Post Transplant Distal Limb Syndrome Other Serious 18 Male 10/20/2008 Other Health Professional Japan
Primary
Concomitant
Respiratory Failure Other Serious 1/1/2007 37 Male 10/29/2008 Other Health Professional India
Primary
Secondary
Concomitant
Sepsis Death 55 Male 10/21/2008 United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 50 Female 11/6/2008 Physician Japan
Primary
Concomitant
Staphylococcal Infection Other Serious 70 Male 11/17/2008
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 6/1/2007 26 Female 11/18/2008 Other Health Professional Japan
Primary
Concomitant
Visual Acuity Reduced Other Serious 6/1/2007 26 Female 11/18/2008 Other Health Professional Japan
Primary
Concomitant
Hypertrophic Cardiomyopathy Other Serious 0 Male 11/19/2008 Japan
Primary
Concomitant
Hypertrophic Cardiomyopathy Other Serious 0 Male 12/1/2008 Japan
Primary
Concomitant
Vision Blurred Other Serious 28 Female 12/1/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Ulcerative Keratitis Other Serious 39 Male 11/20/2008 United Kingdom
Primary
Secondary
Aplasia Pure Red Cell Other Serious Female 12/4/2008 Physician Australia
Primary
Concomitant
Viral Infection Other Serious 10 Male 12/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Disorder Death 43 Female 12/2/2008 Japan
Primary
Concomitant
Pneumococcal Infection Other Serious 33 Female 12/3/2008 United Kingdom
Primary
Secondary
Glomerulonephritis Rapidly Progressive Other Serious 54 Female 249 lb 12/12/2008
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 0 Male 12/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Immunodeficiency Other Serious Female 12/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Urinary Tract Infection Death 43 Female 12/29/2008 Physician United Kingdom
Primary
Secondary
Neuromyelitis Optica Death 43 Female 12/31/2008 Physician United Kingdom
Primary
Secondary
Immunodeficiency Other Serious 33 Female 1/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Disorder Other Serious 33 Female 1/2/2009 Physician United Kingdom
Primary
Secondary
Anti-neutrophil Cytoplasmic Antibody Positive Vasculitis Other Serious 1/2/2009 Other Health Professional Greece
Primary
Secondary
Anti-neutrophil Cytoplasmic Antibody Positive Vasculitis Other Serious 1/2/2009 Other Health Professional Greece
Primary
Secondary
Anti-neutrophil Cytoplasmic Antibody Positive Vasculitis Other Serious 1/5/2009 Other Health Professional Greece
Primary
Secondary
Respiratory Tract Infection Other Serious 7 Male 1/5/2009 Other Health Professional Netherlands
Primary
Secondary
Thrombotic Thrombocytopenic Purpura Other Serious 12/27/2008 Male 150 lb 1/13/2009 United States
Primary
Concomitant
Wheezing Other Serious 4/9/2008 Male 162 lb 1/13/2009 Other Health Professional United States
Primary
Concomitant
Vasculitis Hospitalization 10/14/2008 Male 1/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Blood Immunoglobulin M Decreased Other Serious 7/1/2006 30 Female 1/23/2009 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data