Cyclophosphamide combined with Metronidazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urticaria Hospitalization 7/1/2004 77 Male 3/6/2006
Primary
Secondary
Wound Dehiscence Hospitalization 2/17/2006 58 Female 168 lb 3/31/2006 Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 Female 168 lb 4/7/2006 Physician Germany
Primary
Concomitant
Tachyarrhythmia Hospitalization 1/1/2006 Male 150 lb 4/7/2006 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 Male 132 lb 4/18/2006 Physician Germany
Primary
Concomitant
Wound Dehiscence Hospitalization 2/17/2006 58 Female 168 lb 4/11/2006 Germany
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 1/1/2006 Male 150 lb 5/5/2006 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Female 168 lb 5/5/2006 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 Male 132 lb 5/5/2006 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Female 168 lb 5/8/2006 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 Male 132 lb 5/8/2006 Physician Germany
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 1/1/2006 Male 150 lb 5/8/2006 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Female 168 lb 6/7/2006 Physician Germany
Primary
Concomitant
Staphylococcal Sepsis Hospitalization 1/1/2006 Male 150 lb 6/7/2006 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 Male 132 lb 6/7/2006 Physician Germany
Primary
Concomitant
Sepsis Hospitalization 8/5/2006 59 Female 143 lb 9/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Abscess Other Serious 9/1/2005 60 Female 10/19/2006 Physician United Kingdom
Primary
Concomitant
Skin Lesion Other Serious 0 Male 2/15/2007 Other Health Professional Turkey
Primary
Secondary
Concomitant
Pancytopenia Death 3/10/2007 37 Female 165 lb 3/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/1/2006 62 Male 179 lb 4/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Viral Pharyngitis Other Serious 8/26/2005 19 Male 5/11/2007 Poland
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 62 Male 179 lb 5/6/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/5/2006 52 Male 5/21/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 6/7/2007 Female 202 lb 6/11/2007 United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 9/1/2007 Female 121 lb 10/24/2007 Physician Germany
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 126 lb 11/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 15 Female 11/30/2007 Other Health Professional United States
Primary
Secondary
Staphylococcal Infection Other Serious 21 Male 12/3/2007 Other Health Professional Greece
Primary
Secondary
Lymphoproliferative Disorder Hospitalization 15 Female 12/7/2007
Primary
Secondary
Concomitant
Tumour Marker Increased Life Threatening 9/1/2007 Female 121 lb 12/21/2007 Physician Germany
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 57 lb 12/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 9/1/2007 Female 121 lb 1/4/2008 Physician Germany
Primary
Secondary
Concomitant
Abdominal Abscess Life Threatening 7/19/2008 45 Male 143 lb 9/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 9/29/2008 Korea, Republic Of
Primary
Secondary
Concomitant
Mucosal Inflammation Death 6 40 lb 6/18/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Septic Shock Death 9/19/2008 Male 10/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Visual Impairment Other Serious 4/21/2008 Male 36 lb 11/4/2008 Pharmacist Brazil
Primary
Concomitant
Insomnia Required Intervention 8/23/2008 42 Male 370 lb 12/2/2008 Physician United Kingdom
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 12/28/2008 62 Male 2/9/2009 Physician United States
Primary
Secondary
Concomitant
Haematoma Life Threatening 1/22/2009 Female 2/13/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 12/20/2008 62 Male 2/23/2009 Physician United States
Primary
Secondary
Concomitant
Rectal Ulcer Hospitalization 10/20/2008 Female 4/15/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/6/2009 11 Male 84 lb 4/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 1/15/2009 11 Male 4/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Life Threatening 2/24/2009 Male 5/4/2009 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Other Serious 1/6/2009 11 Male 82 lb 5/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Death 67 4/30/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Staphylococcal Infection Required Intervention 67 5/1/2009 Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 4/27/2009 Male 5/19/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Tachycardia Hospitalization 45 Female 5/22/2009
Primary
Secondary
Blood Sodium Decreased Hospitalization 1/21/2009 Female 6/4/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Rectal Ulcer Hospitalization 10/20/2008 Female 6/4/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/29/2008 Female 6/4/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Blood Sodium Decreased Hospitalization 1/21/2009 Female 6/24/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Rectal Ulcer Hospitalization 10/20/2008 Female 6/24/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/29/2008 Female 6/24/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/29/2008 Female 6/30/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/15/2009 Female 7/1/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/28/2009 36 Female 7/2/2009 Physician India
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Life Threatening 2/24/2009 Male 7/1/2009 Other Health Professional France
Primary
Secondary
Concomitant
Blood Sodium Decreased Hospitalization 1/21/2009 Female 7/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/15/2009 Female 7/14/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/29/2008 Female 7/15/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pseudomembranous Colitis Death 5/12/2009 Female 7/15/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pseudomembranous Colitis Death 5/12/2009 Female 7/20/2009 Other Health Professional France
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 3/1/2004 57 Male 7/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Streptococcal Infection Death 3/1/2004 57 Male 7/20/2009 United Kingdom
Primary
Secondary
Concomitant
Toxoplasmosis Other Serious 15 Female 7/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 7/31/2009 United States
Primary
Concomitant
Pseudomembranous Colitis Life Threatening 5/12/2009 Female 8/18/2009 Other Health Professional France
Primary
Secondary
Concomitant
Rectal Ulcer Hospitalization 10/20/2008 Female 8/21/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/29/2008 Female 8/24/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/15/2009 Female 8/26/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Blood Sodium Decreased Hospitalization 1/21/2009 Female 8/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/8/2008 70 Female 9/1/2009 United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 10/29/2008 Female 92 lb 9/8/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/15/2009 Female 92 lb 9/8/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/8/2008 70 Female 9/3/2009 United States
Primary
Concomitant
Thrombotic Microangiopathy Life Threatening 2/24/2009 Male 9/14/2009 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2007 69 Female 9/17/2009 United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 10/29/2008 Female 92 lb 10/5/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Rectal Ulcer Hospitalization 10/20/2008 Female 10/9/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Blood Sodium Decreased Hospitalization 1/21/2009 Female 10/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2007 69 Female 10/16/2009 United States
Primary
Concomitant
Swollen Tongue Other Serious 10/22/2009 Female 158 lb 10/23/2009 Pharmacist United States
Primary
Concomitant
Blood Sodium Decreased Hospitalization 1/21/2009 Female 10/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 10/26/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 11/9/2009 United States
Primary
Concomitant
Respiratory Failure Hospitalization 6/30/2009 Female 92 lb 11/17/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 10/29/2008 Female 92 lb 11/18/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/21/2009 Female 11/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 4/27/2009 Male 11/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 11/17/2009 United States
Primary
Concomitant
Thrombosis Other Serious 11/1/2009 43 Male 12/8/2009 Physician Chile
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 12/1/2009 United States
Primary
Concomitant
Sinusitis Hospitalization 10/20/2008 Female 12/24/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 10/29/2008 Female 92 lb 12/24/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/21/2009 Female 12/24/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Streptococcal Infection Death 3/1/2004 57 Male 1/6/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Streptococcal Infection Death 3/1/2004 57 Male 1/7/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/6/2009 11 Male 84 lb 1/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 1/15/2009 11 Male 83 lb 1/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 1/15/2009 11 Male 83 lb 2/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxoplasmosis Hospitalization 15 Female 4/9/2010 France
Primary
Secondary
Concomitant
Toxoplasmosis Other Serious 15 Female 4/26/2010 Physician France
Primary
Concomitant
Toxoplasmosis Other Serious 15 Female 6/15/2010 France
Primary
Concomitant
Pyrexia Other Serious 1/9/2009 58 Female 97 lb 7/28/2010 Physician Japan
Primary
Concomitant
Vertigo Hospitalization 1/1/2000 Female 9/10/2010 Physician Sweden
Primary
Concomitant
Interacting
Strongyloidiasis Other Serious 49 Male 9/21/2010
Primary
Secondary
Concomitant
Ultrasound Kidney Abnormal Other Serious 49 Male 9/30/2010 Greece
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/1/2000 Female 10/13/2010 Physician Sweden
Primary
Concomitant
Interacting
Sinusitis Hospitalization 10/20/2008 62 Female 88 lb 12/15/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Death 10/14/2010 49 Male 2/23/2011 Physician United States
Primary
Concomitant
Abdominal Distension Other Serious 10/7/2010 49 Male 3/10/2011 Other Health Professional United States
Primary
Concomitant
Bacteroides Test Positive Hospitalization 78 Male 3/30/2011 Physician New Zealand
Primary
Secondary
Febrile Neutropenia Hospitalization 2/18/2009 59 Male 158 lb 4/20/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Rectal Ulcer Hospitalization 9/12/2009 63 Female 92 lb 5/20/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 63 Male 6/15/2011 Other Health Professional United States
Primary
Secondary
Sepsis Death 5/13/2011 81 Female 6/16/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 5/13/2011 81 Female 6/24/2011 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/7/2010 49 Male 6/29/2011 Other Health Professional United States
Primary
Concomitant
Pulseless Electrical Activity Death 1/25/2011 66 Male 6/30/2011 Other Health Professional United States
Primary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 4/16/2011 59 Female 7/13/2011 Physician United Kingdom
Primary
Concomitant
Disease Progression Death 7/17/2008 45 Male 143 lb 8/11/2011 Physician United States
Primary
Secondary
Concomitant
Skin Hyperpigmentation Death 6/20/2011 11 Female 77 lb 8/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 7/17/2008 45 Male 143 lb 8/25/2011 Physician United States
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 3/2/2011 77 Female 163 lb 9/15/2011 Consumer Brazil
Primary
Concomitant
Tremor Other Serious 9/1/2009 55 Female 164 lb 9/13/2011 Lawyer United States
Primary
Concomitant
Arteriosclerosis Other Serious Male 9/22/2011 Lawyer United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2011 8 Female 49 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Methylobacterium Infection Other Serious 8 Female 49 lb 10/6/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2011 8 Female 49 lb 10/21/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 10/31/2007 35 Female 116 lb 10/19/2011 Consumer United States
Primary
Concomitant
Headache Other Serious 6/20/2011 11 Female 77 lb 10/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 8/23/2011 13 Male 92 lb 11/3/2011 Pharmacist Brazil
Primary
Secondary
Concomitant
Interacting
Headache Hospitalization 6/1/2011 22 Female 11/10/2011 Physician United States
Primary
Secondary
Septic Shock Hospitalization 11/17/2011 65 Female 12/19/2011 Denmark
Primary
Secondary
Concomitant
Liver Disorder Other Serious 1/1/2011 8 Female 49 lb 12/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/29/2011 Physician Germany
Primary
Secondary
Concomitant
Escherichia Infection Other Serious 12/29/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Death Death 12/29/2011 Physician Germany
Primary
Secondary
Concomitant
Nausea Death 12/29/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 12/29/2011 Physician Germany
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Death 12/29/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 12/29/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Herpes Virus Infection Other Serious 12/29/2011 Physician Germany
Primary
Secondary
Concomitant
Oedema Other Serious 12/29/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious 12/29/2011 Physician Germany
Primary
Secondary
Concomitant
Sepsis Death 12/29/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 12/29/2011 Other Health Professional Germany
Primary
Secondary
Concomitant

Drug Data