Cyclophosphamide combined with Methylprednisolone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Venoocclusive Liver Disease Hospitalization 1/1/2004 40 Female 1/4/2006 Physician Slovenia
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 10/28/2005 66 Male 1/9/2006 Physician
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 1/1/2004 40 Female 12/28/2005
Primary
Secondary
Respiratory Distress Hospitalization 12/9/2005 72 Male 163 lb 1/20/2006 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 38 Female 1/23/2006 Physician France
Primary
Secondary
Concomitant
Tachycardia Hospitalization 1/17/2006 Male 77 lb 1/30/2006 United States
Primary
Secondary
Cerebral Haemorrhage Death 11/9/2005 66 Male 2/3/2006 Physician
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 1 Male 1/25/2006 Physician Japan
Primary
Concomitant
Post Procedural Complication Death 34 Male 2/7/2006 Physician Japan
Primary
Concomitant
Hemiplegia Death 34 Male 2/16/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/27/2005 67 Male 2/17/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Pseudomonal Sepsis Other Serious 46 Male 2/22/2006 Physician Japan
Primary
Concomitant
Transaminases Increased Other Serious 19 Female 3/4/2006 Physician Korea, Republic Of
Primary
Concomitant
Carditis Death 24 Female 3/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Spinal Myelogram Abnormal Other Serious 34 Female 3/21/2006 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 8/6/2004 57 Male 3/17/2006 Physician Japan
Primary
Concomitant
Rash Generalised Hospitalization 1/13/2006 59 Female 3/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pseudomonal Sepsis Other Serious 4/17/2002 46 Male 143 lb 3/29/2006 Physician Japan
Primary
Concomitant
Stem Cell Transplant Hospitalization 1/13/2006 59 Female 4/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Gastric Haemorrhage Death 4/17/2006 70 Female 5/3/2006 Physician Hungary
Primary
Secondary
Concomitant
Respiratory Failure Death 67 Male 5/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Left Ventricular Failure Death 4/17/2006 70 Female 5/23/2006 Physician Hungary
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 14 Female 5/31/2006 Physician United States
Primary
Secondary
Concomitant
Human Herpesvirus 6 Infection Death 34 Male 5/23/2006 Physician Japan
Primary
Concomitant
White Blood Cells Urine Positive Death 4/17/2006 70 Female 6/5/2006 Physician Hungary
Primary
Secondary
Concomitant
Graft Versus Host Disease Death 3/28/2003 31 Male 4/27/2006 Japan
Primary
Concomitant
Renal Necrosis Other Serious 6 Female 6/30/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/2/2006 Male 9 lb 7/5/2006 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Death 8/8/2005 67 Female 159 lb 7/10/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 6 Female 7/13/2006 United States
Primary
Secondary
Visual Field Defect Other Serious Female 7/13/2006
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 5 Female 7/21/2006 Other Health Professional Macedonia, The Former Yugoslav Republic Of
Primary
Secondary
Concomitant
Urine Sodium Increased Other Serious 9 Male 7/28/2006 Other Health Professional Japan
Primary
Concomitant
Respiratory Disorder Hospitalization 7/4/2006 34 Male 163 lb 7/31/2006 Physician France
Primary
Secondary
Constipation Hospitalization 3/24/2006 42 Female 108 lb 8/3/2006 Physician France
Primary
Secondary
Cerebral Atrophy Hospitalization 11/9/2004 68 Female 106 lb 8/7/2006 Physician France
Primary
Secondary
Staphylococcal Bacteraemia Death 8/8/2005 67 Female 159 lb 8/14/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Constipation Hospitalization 3/24/2006 42 Female 108 lb 8/21/2006 Other Health Professional France
Primary
Secondary
Status Epilepticus Other Serious 10 Female 9/1/2006 Spain
Primary
Concomitant
Plasmacytoma Other Serious 54 Male 9/21/2006 Consumer United States
Primary
Secondary
Pyrexia Death 7/11/2006 60 Female 97 lb 10/9/2006 Other Health Professional Hungary
Primary
Secondary
Concomitant
Transfusion Reaction Death 56 Female 10/16/2006 Physician Japan
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Other Serious 28 Male 10/10/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Hospitalization 34 Male 10/10/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Hospitalization 30 Male 10/10/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Hospitalization 38 Unknown 10/10/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 19 Male 10/10/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Hospitalization 22 Male 10/10/2006 Physician Japan
Primary
Concomitant
Peptic Ulcer Death 53 Male 10/6/2006 Physician Japan
Primary
Concomitant
Post Procedural Complication Hospitalization 53 Male 10/31/2006 Physician Japan
Primary
Concomitant
Gastrointestinal Ulcer Hospitalization 22 Male 10/30/2006 Physician Japan
Primary
Concomitant
Transplant Rejection Other Serious 6/21/2004 60 Male 187 lb 10/26/2006 Physician Japan
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 34 Male 10/31/2006 Physician Japan
Primary
Concomitant
Post Procedural Complication Hospitalization 30 Male 10/31/2006 Physician Japan
Primary
Concomitant
Gastrointestinal Ulcer Hospitalization 38 10/31/2006 Physician Japan
Primary
Concomitant
Gastrointestinal Ulcer 19 Male 10/31/2006 Physician Japan
Primary
Concomitant
Gastrointestinal Ulcer 28 Male 10/31/2006 Physician Japan
Primary
Concomitant
Tuberculosis Other Serious 6/1/1994 38 Male 11/15/2006 Other Health Professional Turkey
Primary
Secondary
Concomitant
Thrombophlebitis Other Serious 1/1/2003 34 Female 11/21/2006 Japan
Primary
Concomitant
Pyrexia Death 7/11/2006 60 Female 97 lb 11/16/2006 Physician Hungary
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 6/21/2004 60 Male 187 lb 11/14/2006 Physician Japan
Primary
Secondary
Concomitant
Proteinuria Other Serious 9 Male 12/19/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Vith Nerve Paralysis Other Serious 9/27/2006 25 Female 1/25/2007 Physician United States
Primary
Concomitant
Varicella Other Serious 61 Female 1/22/2007 Physician Japan
Primary
Concomitant
Systemic Candida Death 1 Male 2/6/2007 Physician Taiwan, Province Of China
Primary
Secondary
Staphylococcal Infection Life Threatening 8/17/2005 73 Male 4/3/2007 Physician Japan
Primary
Secondary
Concomitant
Gastric Cancer Life Threatening 12/18/2006 65 Female 4/5/2007 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Disease Death 47 Male 5/20/2007 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 2/1/2006 76 Male 6/20/2007 Other Health Professional Finland
Primary
Secondary
Concomitant
Guillain-barre Syndrome Other Serious 51 Male 6/30/2007 Physician Italy
Primary
Concomitant
Visual Field Defect Other Serious 8 Male 6/20/2007 Physician Japan
Primary
Concomitant
Parvovirus Infection Death 7 Female 55 lb 7/6/2007 Physician Greece
Primary
Concomitant
Bone Marrow Failure Other Serious 5/9/2007 Male 159 lb 7/11/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Parvovirus Infection Other Serious 7 Female 7/12/2007 Consumer United States
Primary
Secondary
Concomitant
Parvovirus Infection Death 7 Female 7/14/2007 Physician Greece
Primary
Secondary
Bone Marrow Failure Other Serious 5/9/2007 Male 159 lb 7/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Parvovirus Infection Death 7 Female 55 lb 7/23/2007 Physician Greece
Primary
Secondary
Unresponsive To Stimuli Life Threatening 7/1/2007 67 Male 8/8/2007 Physician United Kingdom
Primary
Concomitant
Neutropenia Other Serious 70 Female 8/17/2007 United Kingdom
Primary
Secondary
Concomitant
Telangiectasia Hospitalization 38 Male 8/21/2007 United Kingdom
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Other Serious 1/1/2002 71 Male 9/4/2007
Primary
Concomitant
Systemic Sclerosis Other Serious 38 Male 148 lb 9/14/2007 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 51 Male 9/5/2007 Physician Italy
Primary
Secondary
Parvovirus Infection Death 10/15/2006 7 Female 55 lb 9/20/2007 Physician Greece
Primary
Secondary
Toxic Epidermal Necrolysis Required Intervention 10 Male 9/17/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Demyelinating Polyneuropathy Hospitalization 4/3/2007 Female 99 lb 9/27/2007 Physician Japan
Primary
Concomitant
Drug Ineffective Life Threatening 46 Male 10/2/2007 Physician Czech Republic
Primary
Concomitant
Vasculitis Hospitalization 1/29/2007 Male 10/2/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 10/3/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Uveitis Other Serious 25 Female 10/8/2007
Primary
Secondary
Stem Cell Transplant Hospitalization 4 Female 9/7/2007 Belgium
Primary
Secondary
Concomitant
Somnolence Other Serious 8/1/2007 8 Male 88 lb 10/12/2007 Pharmacist Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 11/15/2006 7 Female 10/13/2007 Greece
Primary
Secondary
White Blood Cell Count Decreased Death 11/15/2006 7 Female 10/13/2007 Greece
Primary
Secondary
Renal Failure Acute Other Serious 28 Male 10/15/2007 Consumer Switzerland
Primary
Secondary
Neutropenia Other Serious 73 Male 10/15/2007
Primary
Secondary
Concomitant
Ureaplasma Infection Other Serious 28 Male 10/15/2007 Switzerland
Primary
Secondary
Concomitant
Immunosuppression Other Serious 4/19/2007 7 Female 10/16/2007 Consumer Greece
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 28 Male 10/17/2007
Primary
Secondary
Concomitant
Immunosuppression Other Serious 11/15/2006 7 Female 55 lb 10/19/2007 Consumer Greece
Primary
Secondary
Concomitant
Tachycardia Life Threatening 9/28/2007 21 Female 150 lb 10/16/2007 Physician United States
Primary
Secondary
Concomitant
Ureaplasma Infection Hospitalization 28 Male 10/11/2007 Switzerland
Primary
Secondary
Parvovirus Infection Death 10/15/2006 7 Female 55 lb 10/23/2007 Physician Greece
Primary
Secondary
Parvovirus Infection Death 11/15/2006 7 Female 55 lb 10/23/2007 Physician United States
Primary
Secondary
Muscular Weakness Hospitalization 58 Female 10/23/2007
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 29 10/26/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sarcoidosis Life Threatening 7/1/2007 67 Male 10/19/2007 Physician United Kingdom
Primary
Concomitant
Parvovirus Infection Death 11/15/2006 7 Female 55 lb 10/25/2007 Other Health Professional Greece
Primary
Secondary
Histiocytosis Haematophagic Other Serious 4/3/2007 7 Female 55 lb 10/31/2007 Consumer Greece
Primary
Secondary
Concomitant
Parvovirus Infection Death 1/1/2007 7 Female 55 lb 10/27/2007 Physician Greece
Primary
Secondary
Staphylococcal Infection Life Threatening 1/1/2007 8 Male 88 lb 10/31/2007 Physician United States
Primary
Secondary
Concomitant
Vasculitis Other Serious 15 Male 11/5/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Somnolence Other Serious 8/1/2007 8 Male 88 lb 11/8/2007 Physician Canada
Primary
Secondary
Concomitant
Strongyloidiasis Hospitalization 40 Female 11/2/2007 Physician India
Primary
Secondary
Concomitant
Tracheitis Hospitalization 9/30/2007 16 Female 132 lb 11/12/2007 Physician Argentina
Primary
Secondary
Concomitant
Ureaplasma Infection Other Serious 28 Male 11/5/2007 Switzerland
Primary
Secondary
Concomitant
Hypertension Required Intervention 11 Male 11/5/2007 Saudi Arabia
Primary
Secondary
Staphylococcal Infection Life Threatening 8/18/2007 8 Male 88 lb 11/12/2007 Physician United States
Primary
Secondary
Concomitant
Disease Progression Death 62 Male 11/8/2007 Physician France
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious 48 Female 11/16/2007 Other Health Professional France
Primary
Secondary
Visual Acuity Reduced Other Serious 1/1/2001 27 Male 11/19/2007 Other Health Professional Brazil
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10 Male 11/8/2007 Sweden
Primary
Secondary
Concomitant
Tachycardia Life Threatening 9/28/2007 21 Female 150 lb 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 6/26/2007 57 Female 12/3/2007 Consumer United States
Primary
Concomitant
Vasculitis Hospitalization 1/29/2007 Male 12/4/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 9/28/2007 21 Female 150 lb 12/3/2007 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10 Male 12/14/2007 Sweden
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 9/30/2007 16 Female 132 lb 12/20/2007 Physician Argentina
Primary
Secondary
Concomitant
Weight Increased Other Serious 11/1/2005 11 Female 101 lb 12/31/2007 Japan
Primary
Concomitant
Systemic Sclerosis Other Serious 1/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Systemic Lupus Erythematosus Hospitalization 9/30/2007 16 Female 132 lb 1/11/2008 Physician Argentina
Primary
Secondary
Concomitant
Telangiectasia Hospitalization 38 Male 1/11/2008 United Kingdom
Primary
Secondary
Concomitant
Telangiectasia Hospitalization 38 Male 1/11/2008 United Kingdom
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 1/17/2008 Male 42 lb 1/20/2008 United States
Primary
Secondary
Liver Disorder Hospitalization 1/17/2008 Male 42 lb 1/25/2008 United States
Primary
Secondary
Systemic Lupus Erythematosus Hospitalization 9/30/2007 16 Female 128 lb 2/4/2008 Physician Argentina
Primary
Secondary
Concomitant
Vasculitis Hospitalization 1/29/2007 Male 2/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 11/15/2006 7 Female 2/13/2008 Greece
Primary
Secondary
Systemic Lupus Erythematosus Hospitalization 9/30/2007 16 Female 128 lb 2/15/2008 Physician Argentina
Primary
Secondary
Concomitant
Bronchopulmonary Aspergillosis Other Serious 9 Male 2/22/2008 United States
Primary
Secondary
Concomitant
Transplant Failure Other Serious 17 Male 2/22/2008 United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 8 Male 2/22/2008 United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 56 Male 2/25/2008 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 45 Female 2/25/2008 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 45 Female 2/27/2008 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Death 56 Male 2/27/2008 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Death 56 Male 3/5/2008 Consumer United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Death 45 Female 3/5/2008 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Death 45 Female 3/5/2008 Physician United States
Primary
Secondary
Serositis Death 1 3/6/2008 Consumer Japan
Primary
Concomitant

Drug Data