Cyclophosphamide combined with Methylprednisolone Sodium Succinate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Plasmacytoma Other Serious 54 Male 2/22/2006 Physician United States
Primary
Secondary
Carditis Death 24 Female 3/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Vasculitis Life Threatening 2/8/2005 77 Female 110 lb 4/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Carditis Death 24 Female 12/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Renal Failure Acute Hospitalization 12/2/2006 15 Male 126 lb 1/16/2007 Other Health Professional France
Primary
Secondary
Concomitant
Sepsis Death 46 Female 11/21/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 44 Female 2/6/2008 Korea, Republic Of
Primary
Secondary
Renal Necrosis Other Serious 48 Male 6/20/2008 United Kingdom
Primary
Secondary
Toxic Shock Syndrome Staphylococcal Hospitalization 52 Female 8/22/2008 Other Health Professional France
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 2/29/2008 21 Female 95 lb 10/21/2008 Pharmacist United States
Primary
Concomitant
Neuralgia Disability 5/1/2008 48 Female 3/16/2009 Other Health Professional France
Primary
Secondary
Concomitant
Ileus Hospitalization 4/7/2009 Male 5/26/2009 Physician Japan
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Recurrent Death 47 Male 6/17/2009 Physician Japan
Primary
Concomitant
Pseudomonal Sepsis Other Serious 3/4/2009 60 Male 150 lb 6/15/2009 Physician Japan
Primary
Concomitant
Renal Necrosis Other Serious 48 Male 9/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Renal Necrosis Other Serious 45 10/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Precursor T-lymphoblastic Lymphoma/leukaemia Other Serious 2/1/2009 12 Male 12/2/2009 Other Health Professional Japan
Primary
Concomitant
Neonatal Respiratory Distress Syndrome Other Serious 1/6/2009 Female 5 lb 12/15/2009 Physician Switzerland
Primary
Secondary
Concomitant
Pyrexia Other Serious 8 Female 12/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Herpes Virus Infection Hospitalization 10/17/2009 Male 1/4/2010 Physician Italy
Primary
Secondary
Concomitant
Pulmonary Mycosis Life Threatening 5/26/2009 20 Female 2/1/2010 Physician Italy
Primary
Secondary
Concomitant
Stomatitis Hospitalization 3/30/2009 Male 2/1/2010 Physician Italy
Primary
Secondary
Pulmonary Mycosis Life Threatening 5/26/2009 20 Female 2/3/2010 Physician Italy
Primary
Secondary
Concomitant
Melaena Hospitalization 6/8/2009 Male 2/2/2010 Physician Italy
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/27/2009 64 Female 123 lb 2/11/2010 Physician Japan
Primary
Secondary
Concomitant
Cytomegalovirus Infection Hospitalization 9/30/2009 Female 2/15/2010 Physician Italy
Primary
Secondary
Concomitant
Pyrexia Other Serious 3/22/2009 15 Male 110 lb 2/26/2010 Physician Japan
Primary
Concomitant
Pulmonary Mycosis Life Threatening 5/26/2009 Female 3/4/2010 Physician Italy
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/16/2009 Male 161 lb 3/4/2010 Physician Japan
Primary
Concomitant
Pulmonary Mycosis Life Threatening 5/26/2009 20 Female 3/12/2010 Physician Italy
Primary
Secondary
Concomitant
Oral Candidiasis Hospitalization 6/8/2009 Male 3/26/2010 Physician Italy
Primary
Secondary
Concomitant
Neonatal Respiratory Distress Syndrome Other Serious 1/6/2009 Female 5 lb 4/19/2010 Physician Switzerland
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 2/1/2010 74 Male 4/28/2010 Physician Italy
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/29/2010 74 Male 6/11/2010 Physician Italy
Primary
Secondary
Concomitant
Pyrexia Other Serious 3/13/2009 16 Male 108 lb 5/26/2010 Physician Japan
Primary
Secondary
Concomitant
Ventricular Dyskinesia Hospitalization 1 Female 6/10/2010 Italy
Primary
Secondary
Leukopenia Other Serious 77 Female 6/30/2010 Other Health Professional Poland
Primary
Secondary
Skin Striae Other Serious 11/1/2009 13 Female 90 lb 7/15/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/16/2009 23 Male 161 lb 7/20/2010 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/26/2009 11 Male 77 lb 7/21/2010 Physician Japan
Primary
Concomitant
Visual Impairment Other Serious 3/11/2009 49 Female 84 lb 7/21/2010 Physician Japan
Primary
Secondary
Concomitant
Visual Impairment Other Serious 3/11/2009 49 Female 84 lb 7/27/2010 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 77 Female 7/27/2010 Other Health Professional Poland
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/26/2009 11 Male 77 lb 8/11/2010 Physician Japan
Primary
Concomitant
Bacterial Sepsis Other Serious 33 Male 8/13/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 31 Female 8/13/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 19 Male 8/13/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Mycobacterium Kansasii Pneumonia Death 53 Male 8/13/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Disease Recurrence Hospitalization 2/22/2010 49 Female 97 lb 8/13/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 2/16/2009 23 Male 161 lb 9/1/2010 Other Health Professional Japan
Primary
Concomitant
Sepsis Other Serious 4/20/2010 1 Male 15 lb 9/3/2010 Physician Japan
Primary
Concomitant
Serum Ferritin Increased Life Threatening 2/16/2009 24 Male 161 lb 9/8/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 4/20/2010 1 Male 15 lb 9/8/2010 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Hospitalization 2/8/2010 3 Female 31 lb 9/20/2010 Physician Japan
Primary
Concomitant
Device Related Sepsis Hospitalization 11/17/2007 56 Male 179 lb 9/28/2010 Physician France
Primary
Secondary
Drug Ineffective Other Serious 1/1/2009 10/26/2010 Other Health Professional United States
Primary
Concomitant
Pyrexia Death 2/8/2010 38 Male 146 lb 11/8/2010 Physician Japan
Primary
Concomitant
Sepsis Other Serious 5/26/2009 7 Female 29 lb 11/11/2010 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 8/21/2009 13 Male 97 lb 12/8/2010 Physician Japan
Primary
Concomitant
Staphylococcal Sepsis Other Serious 8/18/2009 13 Male 97 lb 12/10/2010 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 4/20/2010 1 Male 15 lb 12/10/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 3/15/2010 54 Female 95 lb 12/22/2010 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 3/19/2010 31 Male 139 lb 12/27/2010 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 3/26/2010 54 Female 95 lb 12/28/2010 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 11/28/2009 73 Male 112 lb 12/29/2010 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Death 10/10/2009 72 Male 112 lb 12/30/2010 Physician Japan
Primary
Concomitant
Pyrexia Death 11/28/2009 73 Male 112 lb 1/3/2011 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 7/1/2009 48 Female 115 lb 1/6/2011 Physician Japan
Primary
Concomitant
Febrile Neutropenia Death 8/11/2010 24 Male 141 lb 1/7/2011 Physician Japan
Primary
Concomitant
Acute Myeloid Leukaemia Recurrent Other Serious 2/26/2010 56 Male 134 lb 1/10/2011 Physician Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 10/21/2009 1/10/2011 Physician Japan
Primary
Concomitant
Blood Pressure Increased Other Serious 8/9/2009 48 Female 115 lb 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Viral Haemorrhagic Cystitis Life Threatening 11/7/2009 66 Male 128 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Hospitalization 2/26/2010 56 Male 134 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Adult T-cell Lymphoma/leukaemia Death Female 126 lb 1/13/2011 Physician Japan
Primary
Secondary
Concomitant
Cytolytic Hepatitis Hospitalization 11/5/2010 32 Female 1/13/2011 Other Health Professional France
Primary
Secondary
Concomitant
Premature Baby Hospitalization 12/25/2003 Female 4 lb 1/18/2011 Physician France
Primary
Secondary
Concomitant
Cytolytic Hepatitis Hospitalization 11/5/2010 32 Female 1/18/2011 Other Health Professional France
Primary
Secondary
Concomitant
Lung Infiltration Hospitalization 7/7/2008 1/20/2011 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 9/10/2009 18 Male 137 lb 1/24/2011 Physician Japan
Primary
Concomitant
Bronchopleural Fistula Other Serious 28 Female 2/9/2011 Physician Japan
Primary
Concomitant
Sepsis Other Serious 9/10/2009 18 Male 137 lb 2/15/2011 Physician Japan
Primary
Concomitant
Haemodialysis Death 7/10/2010 60 Male 163 lb 2/18/2011 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 10/24/2010 19 Male 115 lb 3/10/2011 Physician Japan
Primary
Concomitant
Haemolysis Life Threatening 10/1/2010 53 Male 146 lb 4/1/2011 Physician Japan
Primary
Concomitant
Delirium Other Serious 6/16/2010 53 Male 154 lb 4/8/2011 Physician Japan
Primary
Concomitant
Histiocytosis Haematophagic Hospitalization Female 93 lb 4/11/2011 Physician Japan
Primary
Concomitant
Kidney Transplant Rejection Other Serious 7 Female 4/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bradycardia Other Serious 13 4/4/2011 Physician Netherlands
Primary
Concomitant
Convulsion Other Serious 16 4/4/2011 Physician Netherlands
Primary
Concomitant
Rash Hospitalization 3/15/2010 54 Female 95 lb 4/20/2011 Physician Japan
Primary
Secondary
Concomitant
Bone Marrow Failure Death 57 Female 4/27/2011 Physician Japan
Primary
Secondary
Encephalopathy Hospitalization 3/7/2011 30 Female 4/28/2011 Other Health Professional France
Primary
Secondary
Radiation Pneumonitis Hospitalization 4/6/2011 60 Male 126 lb 5/18/2011 Consumer Japan
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 3/12/2010 54 Female 95 lb 5/19/2011 Physician Japan
Primary
Secondary
Concomitant
Petechiae Other Serious 1/29/2010 49 Male 110 lb 5/20/2011 Physician Japan
Primary
Concomitant
Candida Test Positive Hospitalization 3/12/2010 54 Female 95 lb 5/25/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Effect Decreased Death 2/1/2009 12 Male 7/8/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 11/7/2009 66 Male 128 lb 7/11/2011 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection 10/21/2009 7/12/2011 Physician Japan
Primary
Concomitant
Engraft Failure Other Serious 6/9/2010 10 Female 88 lb 7/15/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 6/9/2010 10 Female 88 lb 7/18/2011 Physician Japan
Primary
Secondary
Concomitant
Hypertension Other Serious 31 Female 7/27/2011 Physician Japan
Primary
Concomitant
Bacterial Sepsis Hospitalization 3/19/2010 31 Male 139 lb 7/29/2011 Physician Japan
Primary
Concomitant
Epstein-barr Virus Test Positive Other Serious 9/13/2009 7 Female 44 lb 8/1/2011 Physician Japan
Primary
Concomitant
Multi-organ Failure Death 11/7/2010 51 Male 137 lb 8/4/2011 Physician Japan
Primary
Concomitant
Rash Hospitalization 3/15/2010 54 Female 95 lb 8/4/2011 Physician Japan
Primary
Secondary
Concomitant
Haemolysis Death 10/1/2010 53 Male 146 lb 8/18/2011 Physician Japan
Primary
Concomitant
Dizziness Hospitalization 9/27/2010 8/22/2011 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 2/7/2011 20 Male 196 lb 8/22/2011 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 5/17/2010 57 Female 134 lb 8/22/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Other Serious 31 Female 8/24/2011 Physician Japan
Primary
Concomitant
Gastritis Hospitalization 11/14/2010 12 Female 106 lb 9/1/2011 Physician Japan
Primary
Concomitant
Haemolytic Anaemia Hospitalization 2/3/2010 6 Male 35 lb 9/19/2011 Physician Japan
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Death 11/17/2009 6 Male 33 lb 9/19/2011 Physician Japan
Primary
Concomitant
Acute Graft Versus Host Disease Hospitalization 1/16/2011 11 Male 84 lb 9/29/2011 Physician Japan
Primary
Concomitant
Pyrexia Death 10/16/2009 38 Female 110 lb 9/29/2011 Physician Japan
Primary
Concomitant
Hypertension Other Serious 6/12/2010 53 Male 154 lb 10/5/2011 Physician Japan
Primary
Concomitant
Pneumonia Cytomegaloviral Other Serious 6/9/2010 10 Female 88 lb 10/12/2011 Physician Japan
Primary
Secondary
Concomitant
Engraft Failure Death 6/9/2010 10 Female 88 lb 10/13/2011 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 10/24/2010 19 Male 97 lb 10/21/2011 Physician Japan
Primary
Concomitant
Bronchopulmonary Aspergillosis Hospitalization 2/26/2010 56 Male 134 lb 10/25/2011 Physician Japan
Primary
Concomitant
Oedema Other Serious 5/26/2009 7 Female 29 lb 11/4/2011 Physician Japan
Primary
Secondary
Concomitant
Insomnia Life Threatening 8/21/2009 13 Male 97 lb 11/4/2011 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Life Threatening 8/21/2009 13 Male 97 lb 11/4/2011 Physician Japan
Primary
Concomitant
Blood Glucose Increased Other Serious 2/11/2011 55 Female 123 lb 11/11/2011 Physician Japan
Primary
Concomitant
Febrile Neutropenia Other Serious 1/9/2011 17 Female 97 lb 11/14/2011 Physician Japan
Primary
Concomitant
Bacterial Sepsis Hospitalization 3/19/2010 31 Male 139 lb 11/15/2011 Physician Japan
Primary
Concomitant
Thrombosis Hospitalization 2/27/2011 39 Male 137 lb 11/17/2011 Physician Japan
Primary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 3/29/2011 36 Male 148 lb 11/21/2011 Physician Japan
Primary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 5/12/2011 6 Female 31 lb 11/22/2011 Physician Japan
Primary
Concomitant
Acute Respiratory Distress Syndrome Death 4/15/2011 3 Female 29 lb 11/23/2011 Physician Japan
Primary
Concomitant
Chronic Myeloid Leukaemia Death 1/4/2011 30 Male 137 lb 11/23/2011 Physician Japan
Primary
Concomitant
Hypoxia Other Serious 5/18/2011 50 Female 84 lb 11/23/2011 Physician Japan
Primary
Concomitant
Rash Hospitalization 11/7/2010 51 Male 137 lb 11/29/2011 Physician Japan
Primary
Concomitant
Pneumonia Staphylococcal Death 6/10/2010 33 Female 101 lb 11/29/2011 Physician Japan
Primary
Concomitant
Chronic Graft Versus Host Disease Other Serious 11/14/2010 12 Female 106 lb 11/30/2011 Physician Japan
Primary
Concomitant
Vomiting Other Serious 4/4/2009 28 Female 115 lb 11/30/2011 Physician Japan
Primary
Concomitant
Sudden Death Death 3/21/2009 47 Male 132 lb 12/5/2011 France
Primary
Secondary
Cytomegalovirus Infection Life Threatening 5/20/2011 34 Female 132 lb 12/6/2011 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Life Threatening 3/2/2011 12 Male 84 lb 12/9/2011 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Life Threatening 7/28/2010 71 Male 159 lb 12/12/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 10/25/2010 11 Male 66 lb 12/12/2011 Physician Japan
Primary
Concomitant
Staphylococcal Bacteraemia Death 11/22/2010 15 Female 95 lb 12/12/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Hepatitis Hospitalization 2/25/2011 2 Male 33 lb 12/12/2011 Physician Japan
Primary
Concomitant
Infection Other Serious 10/1/2010 53 Male 146 lb 12/15/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Recurrent Other Serious 2/26/2010 56 Male 134 lb 12/19/2011 Physician Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 10/13/2010 60 Male 132 lb 12/23/2011 Physician Japan
Primary
Secondary
Concomitant

Drug Data