Cyclophosphamide combined with Mercaptopurine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pancreatitis Necrotising Hospitalization 9/30/2005 7 Female 53 lb 1/23/2006 United States
Primary
Concomitant
Refusal Of Treatment By Relative Other Serious 1/5/2006 Female 124 lb 1/19/2006 United States
Primary
Secondary
Speech Disorder Hospitalization 11/14/2005 20 Female 218 lb 1/26/2006 Pharmacist United Kingdom
Primary
Concomitant
Respiratory Disorder Other Serious 17 Male 2/2/2006 Other Health Professional Ireland
Primary
Secondary
Pseudobulbar Palsy Other Serious 17 Male 2/3/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 2/4/2006 Male 163 lb 2/14/2006 United States
Primary
Secondary
Tongue Paralysis Life Threatening 17 Male 2/15/2006
Primary
Secondary
Pseudobulbar Palsy Other Serious 17 Male 3/1/2006 Physician Ireland
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Life Threatening 1/7/2006 32 Female 130 lb 3/14/2006 Consumer United States
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Life Threatening 1/7/2006 32 Female 130 lb 3/16/2006 Consumer United States
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Life Threatening 1/7/2006 32 Female 130 lb 3/24/2006 Consumer United States
Primary
Concomitant
Urinary Incontinence Hospitalization 48 Female 3/15/2006
Primary
Concomitant
Polyuria Other Serious 13 Female 3/17/2006 United States
Primary
Concomitant
Vomiting Other Serious 3/3/2006 Male 23 lb 4/12/2006 United States
Primary
Secondary
Respiratory Distress Life Threatening 4/18/2006 Female 143 lb 4/19/2006 Pharmacist United States
Primary
Concomitant
Respiratory Distress Life Threatening 4/18/2006 18 Female 143 lb 4/26/2006 Pharmacist United States
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 6 Female 5/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Other Serious 10 Female 5/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Hospitalization 16 Male 5/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 3/1/1997 16 Male 5/1/2006 Physician Spain
Primary
Secondary
Respiratory Distress Life Threatening 4/18/2006 18 Female 143 lb 5/12/2006 Pharmacist United States
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 16 Male 6/2/2006 Physician Canada
Primary
Secondary
Idiopathic Thrombocytopenic Purpura Other Serious 10 Female 6/3/2006 Physician Canada
Primary
Secondary
Staphylococcal Infection Hospitalization 5/9/2006 Female 171 lb 7/7/2006 United States
Primary
Secondary
Mucoepidermoid Carcinoma Other Serious 13 Female 7/25/2006 Physician Turkey
Primary
Secondary
Primitive Neuroectodermal Tumour Death 10 Male 7/25/2006 Physician Turkey
Primary
Secondary
Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Staphylococcal Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Enterobacter Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Bacterial Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Treatment Related Secondary Malignancy Death 10 Male 8/3/2006 Consumer United States
Primary
Secondary
Treatment Related Secondary Malignancy Other Serious 13 Female 8/3/2006 Consumer United States
Primary
Secondary
Treatment Related Secondary Malignancy Death 14 Male 8/3/2006 Consumer United States
Primary
Secondary
Blood Growth Hormone Decreased Other Serious 12 Female 8/4/2006 Other Health Professional United States
Primary
Secondary
Epiphyseal Disorder Other Serious 15 Male 8/4/2006 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 8/14/2006 Female 180 lb 8/15/2006 United States
Primary
Secondary
Concomitant
Urticaria Generalised Hospitalization 8/25/2006 Female 33 lb 8/29/2006 United States
Primary
Secondary
Concomitant
Urinary Incontinence Required Intervention 16 Male 9/1/2006 Other Health Professional Spain
Primary
Concomitant
Urticaria Generalised Hospitalization 8/25/2006 Female 33 lb 9/1/2006 United States
Primary
Secondary
Vertigo Hospitalization 7/16/2006 57 Male 198 lb 9/5/2006 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 8/14/2006 Female 180 lb 9/5/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 9/28/1999 57 Female 8/8/2006 Germany
Primary
Secondary
Concomitant
Urinary Incontinence Required Intervention 1/1/1997 16 Male 9/20/2006 Other Health Professional Spain
Primary
Concomitant
Sepsis Hospitalization 10/21/2006 Male 197 lb 11/6/2006 United States
Primary
Secondary
Sepsis Hospitalization Female 87 lb 11/9/2006 United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 12/1/2006 Male 38 lb 12/6/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 10/18/2006 Female 87 lb 12/13/2006 United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 12/1/2006 Male 38 lb 12/14/2006 United States
Primary
Secondary
Neurotoxicity Other Serious 7/4/2003 17 Female 10/7/2006 United States
Primary
Concomitant
Hepatotoxicity Other Serious 52 Male 1/19/2007 Other Health Professional Israel
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 52 Male 1/18/2007 Physician Israel
Primary
Secondary
Concomitant
Jaundice Cholestatic 52 Male 1/26/2007 Israel
Primary
Secondary
Concomitant
Liver Disorder Other Serious 52 Male 2/7/2007 Israel
Primary
Secondary
Jaundice Cholestatic Other Serious 52 Male 2/23/2007
Primary
Secondary
Somnolence Other Serious 56 Female 3/2/2007
Primary
Secondary
Metastasis Death 11 Female 3/5/2007
Primary
Secondary
Metastasis Death 11 Male 3/5/2007
Primary
Secondary
Metastasis Death 15 Female 3/5/2007
Primary
Secondary
Metastasis Death 12 Male 3/5/2007
Primary
Secondary
Metastasis Death 19 Male 3/5/2007
Primary
Secondary
Metastasis Death 15 Male 3/5/2007
Primary
Secondary
Glioma Other Serious 2 Female 3/8/2007 Consumer Finland
Primary
Secondary
Nervous System Disorder Death 11 Female 3/2/2007 Physician Germany
Primary
Secondary
Glioma Other Serious 2 Male 3/9/2007 Consumer Finland
Primary
Secondary
Glioma Other Serious 2 Female 3/9/2007 Other Health Professional Finland
Primary
Secondary
Glioma Other Serious 4 Male 3/9/2007 Consumer Finland
Primary
Secondary
Glioma Other Serious 3 Female 3/9/2007 Consumer Finland
Primary
Secondary
Glioma Other Serious 5 Male 3/9/2007 Consumer Finland
Primary
Secondary
Glioma Other Serious 2 Male 3/9/2007 Consumer Finland
Primary
Secondary
Glioma Other Serious 2 Female 3/9/2007 Consumer Finland
Primary
Secondary
Glioma Other Serious 2 Female 3/9/2007 Other Health Professional Finland
Primary
Secondary
Glioma Other Serious 3 Female 3/9/2007 Consumer Finland
Primary
Secondary
Glioma Other Serious 4 Male 3/9/2007 Consumer Finland
Primary
Secondary
Glioma Other Serious 5 Male 3/12/2007 Other Health Professional Finland
Primary
Secondary
Glioma Other Serious 5 Male 3/12/2007 Consumer Finland
Primary
Secondary
Treatment Related Secondary Malignancy Death 11 Male 3/1/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 19 Male 3/1/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 15 Male 3/1/2007 Germany
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Death 15 Female 3/1/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 11 Female 3/1/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 12 Male 3/1/2007 Germany
Primary
Secondary
Glioma Death 13 Female 3/1/2007 Germany
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Death 15 Male 3/16/2007 Germany
Primary
Secondary
Glioma Death 19 Male 3/16/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 15 Female 3/16/2007 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Death 12 Male 3/16/2007 Germany
Primary
Secondary
Glioblastoma Multiforme Death 11 Female 3/16/2007 Germany
Primary
Secondary
Pancytopenia Death 3/10/2007 37 Female 165 lb 3/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Glioma Death 13 Female 3/20/2007 Germany
Primary
Secondary
Glioma Death 11 Male 3/20/2007 Germany
Primary
Secondary
Neoplasm Malignant Death 15 Female 3/30/2007 Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Death 13 Female 3/30/2007 Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Death 11 Male 3/30/2007 Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Death 15 Male 3/30/2007 Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Death 19 Male 3/30/2007 Germany
Primary
Secondary
Neoplasm Malignant Death 12 Male 3/30/2007 Germany
Primary
Secondary
Concomitant
Spinal Cord Disorder Other Serious 26 Female 4/4/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Spinal Cord Disorder Other Serious 26 Female 4/10/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Sepsis Death 26 Female 4/11/2007
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 26 Female 4/11/2007 Australia
Primary
Secondary
Concomitant
Spinal Cord Disorder Hospitalization 26 Female 4/13/2007 Consumer United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 26 Female 4/6/2007 Other Health Professional Australia
Primary
Secondary
Deep Vein Thrombosis Other Serious 1/12/2006 Female 160 lb 4/25/2007 United States
Primary
Secondary
Malignant Melanoma Other Serious 22 Male 6/8/2007 Other Health Professional United States
Primary
Secondary
Malignant Melanoma In Situ Other Serious 22 Male 6/12/2007
Primary
Secondary
Malignant Melanoma In Situ Other Serious Male 6/12/2007 United States
Primary
Secondary
Xerosis Hospitalization 11 Male 6/13/2007 Physician United States
Primary
Concomitant
Polyneuropathy Other Serious Female 6/22/2007
Primary
Secondary
Polyneuropathy Other Serious Male 6/22/2007
Primary
Secondary
Wound Abscess Hospitalization 6/6/2007 Male 45 lb 6/21/2007 United States
Primary
Secondary
Respiratory Tract Infection Viral Other Serious 8 Male 6/28/2007 Other Health Professional Australia
Primary
Secondary
Polyneuropathy Other Serious Female 7/5/2007
Primary
Secondary
Polyneuropathy Other Serious Male 7/5/2007
Primary
Secondary
Trichostasis Spinulosa Other Serious 6 Male 6/30/2007 Physician Australia
Primary
Secondary
Malignant Melanoma In Situ Other Serious Male 7/16/2007 United States
Primary
Secondary
Precocious Puberty Other Serious Female 9/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Death 1 Female 9/10/2007 Argentina
Primary
Secondary
Disease Recurrence Death 5 Male 9/10/2007 Argentina
Primary
Secondary
Acute Myeloid Leukaemia Life Threatening 9 Female 9/10/2007 Argentina
Primary
Secondary
Tachycardia Hospitalization 9/5/2007 Male 232 lb 9/19/2007 United States
Primary
Secondary
Post Procedural Complication Hospitalization 14 Male 9/19/2007 Japan
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 9/27/2007 Male 187 lb 10/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
No Therapeutic Response Other Serious 52 Male 10/26/2007 Israel
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 11 Male 10/30/2007 Physician United States
Primary
Concomitant
Systemic Candida Other Serious 26 Male 11/8/2007 Other Health Professional Germany
Primary
Secondary
Systemic Candida Hospitalization 26 Male 11/15/2007 Germany
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 26 Male 11/21/2007 Germany
Primary
Secondary
Concomitant
Glioma Death 13 Female 11/21/2007 Germany
Primary
Secondary
Glioma Death 15 Female 11/21/2007 Germany
Primary
Secondary
Nervous System Disorder Death 12 Male 11/21/2007 Physician Germany
Primary
Secondary
Glioma Death 11 Male 11/21/2007 Germany
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2007 28 Female 12/10/2007 Consumer Japan
Primary
Secondary
Tachycardia Hospitalization 12/12/2007 Male 139 lb 12/13/2007 United States
Primary
Secondary
Tachycardia Hospitalization 12/12/2007 Male 35 lb 12/13/2007 United States
Primary
Secondary
Malignant Melanoma Other Serious 17 Male 12/18/2007 United States
Primary
Secondary
Systemic Candida Hospitalization 26 Male 12/19/2007 Germany
Primary
Secondary
Supraventricular Extrasystoles Hospitalization 12/12/2007 Male 139 lb 12/19/2007 United States
Primary
Secondary
Status Epilepticus Hospitalization 12/16/2007 Female 118 lb 12/28/2007 United States
Primary
Secondary
Skin Lesion Hospitalization 12/24/2007 Male 40 lb 12/27/2007 United States
Primary
Secondary
Pain In Extremity Hospitalization 10/15/2007 Female 110 lb 1/4/2008 United States
Primary
Secondary
Mass Hospitalization 2/4/2008 Physician Hong Kong
Primary
Secondary
Ewing's Sarcoma Other Serious 16 Male 2/13/2008 Other Health Professional Japan
Primary
Secondary
Vomiting Other Serious 2 Female 2/7/2008 Physician Canada
Primary
Secondary
Concomitant
Hypokalaemia Other Serious Female 2/8/2008 Canada
Primary
Concomitant
Haematuria Other Serious 16 Male 2/21/2008 Physician Japan
Primary
Secondary
Pseudomonal Sepsis Hospitalization 2/21/2008 Female 26 lb 2/29/2008 United States
Primary
Secondary
Pancytopenia Hospitalization 2/18/2008 Female 167 lb 3/6/2008 United States
Primary
Secondary
Ewing's Sarcoma Other Serious 16 Male 3/31/2008
Primary
Secondary
Concomitant
Protein Total Decreased Other Serious Male 176 lb 4/21/2008 Pharmacist Australia
Primary
Secondary
Concomitant
Stomatitis Other Serious 16 Male 5/24/2008 Physician Turkey
Primary
Secondary

Drug Data