Cyclophosphamide combined with Levofloxacin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Transplant Rejection Hospitalization 58 Female 12/29/2005 Physician United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Required Intervention 10/1/2005 58 Female 1/16/2006 Physician United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 58 Female 1/19/2006 Physician United States
Primary
Secondary
Concomitant
Post Procedural Complication Death 34 Male 2/7/2006 Physician Japan
Primary
Concomitant
Hemiplegia Death 34 Male 2/16/2006 Physician Japan
Primary
Concomitant
Respiratory Failure Death 8/3/2005 43 Male 4/28/2006 Physician Japan
Primary
Concomitant
Tachycardia Hospitalization 3/17/2006 61 Male 6/2/2006 Physician United States
Primary
Secondary
Concomitant
Human Herpesvirus 6 Infection Death 34 Male 5/23/2006 Physician Japan
Primary
Concomitant
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 6/29/2006 Physician Germany
Primary
Secondary
Concomitant
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 7/13/2006 Physician Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/5/2006 62 Male 7/19/2006 Physician Italy
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/5/2006 62 Male 7/27/2006 Physician Italy
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Required Intervention 55 Female 10/5/2006 Germany
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 7/18/2006 11 Male 66 lb 12/13/2006 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 6/9/2006 11 Male 66 lb 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 2/13/2007 84 Female 178 lb 2/21/2007 Pharmacist United States
Primary
Concomitant
Oesophageal Candidiasis Hospitalization 5/16/2007 Male 168 lb 5/18/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/15/2006 51 Male 5/11/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/15/2006 52 Male 5/18/2007 Physician United States
Primary
Secondary
Concomitant
Oesophageal Candidiasis Hospitalization 5/16/2007 Male 168 lb 5/31/2007 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/26/2005 Male 181 lb 7/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 54 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 61 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 79 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/29/2007 Male 154 lb 10/9/2007 Consumer United States
Primary
Secondary
Concomitant
Mycobacterial Infection Hospitalization 65 Male 10/16/2007
Primary
Secondary
Concomitant
Tracheitis Hospitalization 9/30/2007 16 Female 132 lb 11/12/2007 Physician Argentina
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/26/2007 Male 201 lb 11/16/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/26/2007 Male 201 lb 11/29/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 21 Male 12/3/2007 Other Health Professional Greece
Primary
Secondary
Sudden Death Other Serious 8/14/2007 38 Unknown 12/3/2007 Physician Germany
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 9/28/2007 21 Female 150 lb 12/3/2007 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/26/2007 Male 174 lb 12/12/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 9/30/2007 16 Female 132 lb 12/20/2007 Physician Argentina
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/26/2007 Male 174 lb 1/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 9/30/2007 16 Female 132 lb 1/11/2008 Physician Argentina
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 10/28/2007 Female 143 lb 2/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 10/28/2007 Female 143 lb 2/23/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 2/14/2008 Female 183 lb 2/22/2008 Physician Germany
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 21 Male 2/29/2008 Other Health Professional United States
Primary
Secondary
Suicide Attempt Hospitalization 2/12/2008 Female 183 lb 3/14/2008 Physician Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/26/2007 Male 174 lb 4/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Sinusitis Hospitalization 4/23/2007 9 Female 54 lb 4/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 4/29/2008 Physician Germany
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/27/2008 Male 5/16/2008 Physician Italy
Primary
Concomitant
Systemic Lupus Erythematosus Hospitalization 9/30/2007 Female 106 lb 7/23/2008 Physician Argentina
Primary
Secondary
Concomitant
Bone Pain Other Serious 1/10/2008 30 Male 8/7/2008 Physician Belgium
Primary
Concomitant
Serotonin Syndrome Life Threatening 8/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Bone Pain Other Serious 1/10/2008 30 Male 8/29/2008 Physician Belgium
Primary
Concomitant
Metabolic Acidosis Hospitalization 10/28/2007 Female 143 lb 9/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Urine Abnormality Hospitalization 8/13/2008 78 Male 9/5/2008 Other Health Professional United States
Primary
Concomitant
Bone Pain Other Serious 1/10/2008 30 Male 9/11/2008 Physician Belgium
Primary
Concomitant
Febrile Neutropenia Hospitalization 10/26/2007 Male 174 lb 9/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Life Threatening 10/28/2007 Female 143 lb 9/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Fungaemia Other Serious 57 Female 9/26/2008 Physician Japan
Primary
Concomitant
Fungal Rhinitis Other Serious 41 Male 7/8/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Stomatitis Hospitalization 9/14/2008 Female 10/8/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Stomatitis Hospitalization 9/14/2008 Female 10/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Proctitis Other Serious 10/10/2008 Female 11/12/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 73 Female 12/4/2008
Primary
Secondary
Pyrexia Other Serious 26 Male 12/4/2008
Primary
Secondary
Concomitant
Panic Attack Other Serious Male 12/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/30/2008 64 Male 227 lb 1/5/2009 Other Health Professional United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 1/15/2009 United States
Primary
Secondary
Concomitant
Skin Plaque Other Serious 12 Female 2/5/2009 Physician United States
Primary
Concomitant
Non-hodgkin's Lymphoma Death 5/13/2008 68 Male 2/2/2009 Japan
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 12/28/2008 62 Male 2/9/2009 Physician United States
Primary
Secondary
Concomitant
Neutropenia 1/27/2009 Female 165 lb 2/9/2009 United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 12/20/2008 62 Male 2/23/2009 Physician United States
Primary
Secondary
Concomitant
Vaccination Failure Other Serious 35 Female 2/27/2009 Consumer United States
Primary
Concomitant
Mucosal Inflammation Other Serious 69 Male 3/10/2009 Italy
Primary
Secondary
Mucosal Inflammation Other Serious 69 Male 3/20/2009 Other Health Professional Japan
Primary
Secondary
Vaccination Failure Other Serious 35 Female 4/2/2009 Consumer United States
Primary
Concomitant
Hypoglycaemia Other Serious 8/15/2008 Male 4/3/2009 Physician Japan
Primary
Concomitant
Infection Other Serious 4/14/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Encephalopathy Hospitalization 3/30/2009 Male 5/1/2009 Other Health Professional United Kingdom
Primary
Concomitant
Encephalopathy Hospitalization 3/30/2009 Male 5/15/2009 Other Health Professional United Kingdom
Primary
Concomitant
Osteonecrosis Hospitalization 63 Male 5/22/2009 Consumer Japan
Primary
Concomitant
Pulmonary Toxicity Other Serious 62 Male 5/29/2009
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 63 Male 6/8/2009 Consumer Japan
Primary
Concomitant
Osteonecrosis Hospitalization 63 Male 6/18/2009 Consumer Japan
Primary
Concomitant
Panic Attack Other Serious Male 7/24/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Panic Attack Other Serious Male 8/11/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Life Threatening 7/28/2009 Male 8/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/26/2008 51 Female 128 lb 8/25/2009 Physician United States
Primary
Secondary
Concomitant
Proteinuria Other Serious 6/26/2008 51 Female 9/3/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/26/2008 51 Female 128 lb 9/3/2009 Physician United States
Primary
Secondary
Febrile Bone Marrow Aplasia Life Threatening 7/28/2009 Male 9/3/2009 Physician France
Primary
Secondary
Concomitant
Stomatitis Other Serious 6/26/2008 51 Female 128 lb 9/8/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 9/10/2008 61 Female 93 lb 9/11/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 7/2/2008 49 Male 141 lb 9/11/2009 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 6/25/2008 51 Female 128 lb 9/14/2009 Physician United States
Primary
Secondary
Concomitant
Pleurisy Other Serious 7/1/2007 45 Female 9/22/2009
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 7/2/2008 49 Male 141 lb 9/25/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/9/2009 54 Male 9/30/2009 Physician Japan
Primary
Secondary
Concomitant
Visual Impairment Life Threatening 7/28/2009 Male 10/14/2009 Physician France
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 5/7/2009 43 Female 201 lb 8/31/2009 Pharmacist United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 10/16/2009 Other Health Professional United States
Primary
Secondary
Renal Failure Other Serious 9/23/2009 Male 255 lb 10/28/2009 United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 7/28/2009 Male 10/29/2009 Physician France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 7/28/2009 Male 12/1/2009 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/23/2009 Male 255 lb 12/2/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/23/2009 Male 255 lb 12/2/2009 United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 11/28/2009 Male 12/30/2009 Physician United States
Primary
Concomitant
Stress Other Serious 10/11/2007 56 Female 98 lb 12/31/2009 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 10/11/2007 56 Female 98 lb 1/20/2010 Physician Japan
Primary
Secondary
Concomitant
Bone Marrow Failure Other Serious 42 Female 1/27/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious Male 125 lb 2/15/2010 Physician United States
Primary
Concomitant
Pyrexia Other Serious 3/22/2009 15 Male 110 lb 2/26/2010 Physician Japan
Primary
Concomitant
Supraventricular Tachycardia Other Serious 58 Female 3/9/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious Male 125 lb 3/22/2010 Physician United States
Primary
Concomitant
Septic Shock Death 6/26/2007 76 Male 3/26/2010 Physician Italy
Primary
Secondary
Concomitant
Shock Death 55 Male 4/9/2010 Other Health Professional Japan
Primary
Concomitant
Skin Toxicity Other Serious 4/29/2010 United States
Primary
Secondary
Skin Toxicity Death 4/30/2010 Physician United Kingdom
Primary
Secondary
Thrombosis In Device Other Serious 1 Female 5/27/2010
Primary
Secondary
Respiratory Disorder Other Serious 1/20/2008 8 Female 50 lb 5/26/2010 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/27/2008 79 Male 6/8/2010 Italy
Primary
Concomitant
Hypokalaemia Hospitalization 6/6/2010 19 6/29/2010 Physician Germany
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 6/6/2010 19 7/9/2010 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 7/19/2010 United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Life Threatening 8/4/2010 Other Health Professional Algeria
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 10/6/2008 8/5/2010 Physician France
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2009 55 Male 186 lb 8/6/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 8/6/2010 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/9/2009 58 Female 97 lb 7/28/2010 Physician Japan
Primary
Concomitant
Staphylococcal Infection Life Threatening 10/11/2007 51 Female 165 lb 9/3/2010 Physician France
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 9/17/2010 United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization Male 10/7/2010 Physician United States
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Life Threatening 10/4/2010 46 Male 11/3/2010 Physician Japan
Primary
Secondary
Drug Rash With Eosinophilia And Systemic Symptoms Life Threatening 10/4/2010 46 Male 11/18/2010 Physician Japan
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 8/31/2010 70 Male 12/3/2010 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
Enterococcal Sepsis Death 11 Female 12/17/2010 Physician Italy
Primary
Secondary
Concomitant
Pancytopenia Death 11 Female 12/21/2010 United States
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 8/31/2010 70 Male 12/21/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 3/15/2010 54 Female 95 lb 12/22/2010 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 3/19/2010 31 Male 139 lb 12/27/2010 Physician Japan
Primary
Concomitant
White Blood Cell Disorder Other Serious 12/6/2007 12 Male 80 lb 12/27/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/12/2010 54 Female 95 lb 12/27/2010 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 3/26/2010 54 Female 95 lb 12/28/2010 Physician Japan
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Life Threatening 10/4/2010 46 Male 12/28/2010 Physician Japan
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Recurrent Other Serious 2/26/2010 56 Male 134 lb 1/10/2011 Physician Japan
Primary
Concomitant
Acute Graft Versus Host Disease In Skin Hospitalization 2/26/2010 56 Male 134 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Ileus Other Serious 3/1/2011 Physician United States
Primary
Secondary
Concomitant
Death Other Serious 3/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/28/2011 45 Male 3/8/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 25 Female 3/9/2011 Physician Japan
Primary
Secondary
Concomitant
Chronic Graft Versus Host Disease Other Serious 3/9/2011 Physician Japan
Primary
Secondary
Concomitant

Drug Data