Cyclophosphamide combined with Ibuprofen

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Other Serious 11/11/2004 76 Female 1/3/2006 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 1/21/2005 53 Male 2/16/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/7/2004 67 Female 2/17/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/15/2005 64 Male 2/17/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/17/2005 64 Male 119 lb 3/3/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/4/2004 74 Female 115 lb 3/7/2006 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 8/6/2004 57 Male 3/17/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/6/2005 83 Female 99 lb 3/17/2006 Physician Japan
Primary
Secondary
Concomitant
Myeloid Leukaemia Other Serious 11/4/2004 78 Male 121 lb 4/20/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/8/2006 45 Male 215 lb 5/16/2006 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/6/2005 83 Female 99 lb 5/24/2006 Physician Japan
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 10/15/2005 49 Female 190 lb 6/14/2006 Physician United States
Primary
Concomitant
Vaginal Exfoliation Hospitalization 5/23/2006 Female 139 lb 7/13/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/30/2005 75 Male 7/28/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Death 6/30/2005 79 Male 8/2/2006 Physician Japan
Primary
Secondary
Concomitant
Extravasation Hospitalization 6/9/2006 58 8/10/2006 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/6/2005 83 Female 99 lb 8/22/2006 Physician Japan
Primary
Secondary
Concomitant
Extravasation Hospitalization 6/9/2006 58 8/31/2006 Physician Germany
Primary
Secondary
Concomitant
Pneumonitis Other Serious 53 Male 6/6/2006 Pharmacist United States
Primary
Concomitant
Myeloid Leukaemia Other Serious 11/4/2004 78 Male 121 lb 9/18/2006 Physician Japan
Primary
Secondary
Concomitant
Erythema Multiforme Other Serious 10/11/2006 2 Female 31 lb 10/26/2006 Physician Argentina
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 10/11/2006 2 Female 31 lb 2/6/2007 Physician Argentina
Primary
Concomitant
Urine Output Decreased Death 1/4/2007 Male 3/13/2007 Physician Japan
Primary
Concomitant
Urine Output Decreased Hospitalization 1/4/2007 Male 3/27/2007 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 10/11/2006 2 Female 31 lb 4/3/2007 Physician Argentina
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/22/2007 9 Female 58 lb 6/14/2007 Physician Germany
Primary
Concomitant
Neutropenia Life Threatening 4/27/2007 53 Male 159 lb 6/26/2007 Physician Germany
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Other Serious 10/11/2006 2 Female 31 lb 2/8/2007 Physician Argentina
Primary
Secondary
Concomitant
Wegener's Granulomatosis Hospitalization 4/1/2007 Female 144 lb 7/27/2007 Physician Finland
Primary
Concomitant
Wegener's Granulomatosis Hospitalization 4/1/2007 Female 144 lb 8/7/2007 Physician Finland
Primary
Concomitant
Neutropenic Sepsis Hospitalization 8/2/2007 73 Female 176 lb 10/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/17/2007 Female 177 lb 10/10/2007 Physician United States
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 8/2/2007 Female 10/11/2007
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 1/1/2007 Female 11/14/2007 Pharmacist United Kingdom
Primary
Concomitant
Oral Candidiasis Hospitalization 9/17/2007 73 Female 176 lb 4/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 8/2/2007 Female 4/9/2008 Other Health Professional United States
Primary
Concomitant
Neutropenic Sepsis Hospitalization 9/17/2007 Female 177 lb 4/9/2008 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 3/15/2008 5/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Hodgkin's Disease Stage Ii Other Serious 2 Female 8/15/2008 United States
Primary
Secondary
Dehydration Hospitalization 11/19/2005 Female 270 lb 8/19/2008 Physician United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 11/19/2005 Female 270 lb 8/28/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 9/18/2008 61 Female 282 lb 9/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 10 Female 9/26/2008 Physician United States
Primary
Secondary
Hodgkin's Disease Other Serious 10 Female 9/30/2008 Physician United Kingdom
Primary
Secondary
Hodgkin's Disease Other Serious 10 Female 10/2/2008 Other Health Professional United States
Primary
Secondary
Leukopenia Other Serious 10/30/2008 56 Female 207 lb 12/1/2008 Physician Germany
Primary
Secondary
Concomitant
Neoplasm Progression Hospitalization 11/25/2008 39 Female 165 lb 12/5/2008 Physician Germany
Primary
Secondary
Concomitant
Sinusitis Hospitalization 12/5/2008 Female 137 lb 12/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Plasmacytoma Hospitalization 11/25/2008 39 Female 165 lb 12/15/2008 Physician Germany
Primary
Secondary
Concomitant
Leukopenia Other Serious 10/30/2008 56 Female 207 lb 12/23/2008 Physician Germany
Primary
Secondary
Concomitant
Postoperative Wound Infection Hospitalization 10/8/2007 Female 179 lb 2/3/2009 United Kingdom
Primary
Concomitant
Postoperative Wound Infection Hospitalization 10/8/2007 Female 179 lb 2/5/2009 United Kingdom
Primary
Concomitant
Dehydration Hospitalization 11/20/2005 Female 270 lb 2/13/2009 Physician United States
Primary
Secondary
Concomitant
Myeloid Leukaemia Other Serious 47 Female 2/26/2009
Primary
Secondary
Swollen Tongue Other Serious 1/1/2009 Female 3/6/2009 Pharmacist United Kingdom
Primary
Concomitant
Neutropenia Hospitalization 3/8/2009 Male 4/1/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 1/15/2007 Male 205 lb 4/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/30/2009 35 Female 241 lb 5/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 2 Female 5/8/2009 Other Health Professional United States
Primary
Secondary
Pulmonary Embolism Hospitalization 31 6/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 31 Male 6/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wegener's Granulomatosis Life Threatening 31 Male 6/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Hospitalization 31 Male 6/23/2009 United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 6/16/2009 Female 7/8/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 6/15/2009 Female 7/14/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 6/15/2009 Female 7/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Mania Hospitalization 10/8/2007 69 Female 8/4/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Prurigo Hospitalization 7/22/2009 Female 194 lb 8/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 6/15/2009 Female 180 lb 8/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Prurigo Hospitalization 7/22/2009 Female 194 lb 8/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Bone Pain Other Serious 8/1/2009 Male 8/24/2009 Pharmacist United States
Primary
Concomitant
Leukopenia Life Threatening 10/30/2008 56 Female 207 lb 8/21/2009 Physician Germany
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Life Threatening 7/28/2009 Male 8/28/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Life Threatening 7/28/2009 Male 9/3/2009 Physician France
Primary
Secondary
Concomitant
Leukopenia Other Serious 10/30/2008 56 Female 207 lb 9/10/2009 Physician Germany
Primary
Secondary
Concomitant
Visual Impairment Life Threatening 7/28/2009 Male 10/14/2009 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/7/2009 46 Female 102 lb 10/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 7/28/2009 Male 10/29/2009 Physician France
Primary
Secondary
Concomitant
Neutropenia Other Serious 1/1/2009 58 Female 225 lb 11/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 5/1/2009 Female 225 lb 11/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 12/9/2007 Female 11/16/2009 Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 7/28/2009 Male 12/1/2009 Physician France
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 5/1/2009 Female 225 lb 12/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 8/25/2008 Female 194 lb 1/7/2010 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 8/18/2009 Male 228 lb 1/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 8/18/2009 Male 228 lb 2/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 8/18/2009 Male 228 lb 3/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Erythema Nodosum Disability 12/1/2009 Female 3/19/2010 Consumer Canada
Primary
Concomitant
Weight Decreased Other Serious 1/1/2001 44 Female 134 lb 4/12/2010 Physician United States
Primary
Concomitant
Optic Neuritis Hospitalization 9/29/2009 41 Female 126 lb 4/28/2010 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2001 44 Female 134 lb 5/4/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2001 44 Female 134 lb 6/11/2010 United States
Primary
Concomitant
Urosepsis Hospitalization 7/30/2010 69 Male 205 lb 8/24/2010 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2001 44 Female 134 lb 8/29/2010 United States
Primary
Concomitant
Neutropenia Hospitalization 5/21/2009 57 Female 174 lb 8/31/2010 Physician Australia
Primary
Secondary
Concomitant
Toothache Hospitalization 3/23/2008 19 Female 143 lb 9/28/2010 Consumer
Primary
Secondary
Concomitant
Renal Failure Death 8/1/2010 58 Female 116 lb 10/27/2010 Consumer United Kingdom
Primary
Concomitant
Renal Failure Death 8/1/2010 58 Female 116 lb 11/2/2010 Consumer United Kingdom
Primary
Concomitant
Swollen Tongue Other Serious 1/1/2009 11/19/2010 Pharmacist United Kingdom
Primary
Concomitant
No Therapeutic Response Other Serious 10 Female 3/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Toothache Disability 17 Female 143 lb 10/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Infection Hospitalization 10/16/2009 3/31/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Blood Bilirubin Increased Hospitalization 1/1/2011 51 Female 187 lb 5/9/2011 Physician Germany
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 2/27/2010 5/18/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Vitamin D Deficiency Hospitalization 1/1/2001 44 Female 134 lb 6/6/2011 Other Health Professional United States
Primary
Concomitant
Urticaria Hospitalization 7 Female 6/23/2011 Other Health Professional Turkey
Primary
Secondary
Herpes Zoster Other Serious 10/2/2002 47 Female 128 lb 6/24/2011 Lawyer United States
Primary
Secondary
Concomitant
Dysphagia Other Serious 7/1/2007 5 Male 44 lb 7/1/2011 Physician Japan
Primary
Concomitant
Myopia Other Serious 10/2/2002 47 Female 128 lb 7/25/2011 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/30/2011 50 Female 8/4/2011 Physician Canada
Primary
Concomitant
Cystitis Haemorrhagic Death 3/27/2006 32 Female 8/16/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/30/2011 50 Female 8/18/2011 Physician Canada
Primary
Concomitant
Dizziness Hospitalization 9/27/2010 8/22/2011 Physician Japan
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/30/2011 50 Female 9/2/2011 Physician Canada
Primary
Concomitant
Hyperkalaemia Other Serious 10/2/2002 47 Female 128 lb 9/2/2011 United States
Primary
Secondary
Concomitant
Jaundice Hospitalization 1/1/2011 51 Female 187 lb 9/15/2011 Physician Germany
Primary
Secondary
Concomitant
Onychomycosis Other Serious 5/1/2007 62 Female 149 lb 9/21/2011 Physician United States
Primary
Concomitant
Drug Dose Omission 51 Female 9/22/2011 Consumer United States
Primary
Concomitant
Blood Cholesterol Increased 11/1/2004 51 Female 185 lb 9/22/2011 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 1/1/2004 42 Male 156 lb 9/22/2011 Other Health Professional United States
Primary
Concomitant
Menstruation Irregular 1/1/2003 27 Female 9/22/2011 United States
Primary
Concomitant
Obesity Hospitalization 1/1/2003 38 Female 231 lb 9/22/2011 United States
Primary
Concomitant
Chest Pain Hospitalization 11/8/2010 29 Female 190 lb 9/27/2011 Other Health Professional United States
Primary
Concomitant
Metastases To Peritoneum Other Serious 11/1/2009 61 Female 9/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Melanocytic Naevus Other Serious 1/7/2004 43 Female 170 lb 9/30/2011 Lawyer United States
Primary
Secondary
Concomitant
Intracranial Venous Sinus Thrombosis Other Serious 10/4/2007 42 Female 190 lb 10/6/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypokalaemia Death 10/2/2002 47 Female 128 lb 10/7/2011 Lawyer United States
Primary
Secondary
Concomitant
Fibrin Degradation Products Increased Other Serious 8/26/2010 62 Female 10/12/2011 Consumer Japan
Primary
Secondary
Concomitant
Headache Other Serious 10/2/2002 47 Female 128 lb 10/21/2011 United States
Primary
Secondary
Concomitant
Pseudomonal Bacteraemia Hospitalization 5/12/2011 58 Female 10/25/2011 Physician Netherlands
Primary
Secondary
Concomitant
Pain Hospitalization 12/5/2009 19 Female 118 lb 10/27/2011 Lawyer United States
Primary
Concomitant
Alopecia Male 10/28/2011 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/30/2011 50 Female 10/31/2011 Physician Canada
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/30/2011 50 Female 11/22/2011 Physician Canada
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/30/2011 50 Female 12/7/2011 Physician Canada
Primary
Concomitant
Febrile Neutropenia Hospitalization 5/12/2011 58 Female 12/16/2011 Physician Netherlands
Primary
Secondary
Concomitant
Constipation Other Serious 8/26/2010 62 Female 1/31/2012 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Hospitalization 5/21/2009 57 Female 174 lb 2/13/2012 Australia
Primary
Secondary
Concomitant
Enterocolitis Haemorrhagic Hospitalization 12/13/2011 79 Female 170 lb 2/23/2012 Physician Germany
Primary
Concomitant
Neutropenia Hospitalization 5/21/2009 57 Female 174 lb 2/27/2012 Physician United States
Primary
Secondary
Concomitant
Chest Discomfort Hospitalization 10/15/2011 43 Female 2/28/2012 Pharmacist Ireland
Primary
Concomitant
Dizziness Hospitalization 9/27/2010 60 Male 151 lb 3/8/2012 Physician Japan
Primary
Concomitant
Constipation Other Serious 8/26/2010 62 Female 3/8/2012 Consumer Japan
Primary
Secondary
Concomitant
Anaemia Other Serious 1/21/2011 68 Male 3/14/2012 Other Health Professional United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 5/12/2011 58 Female 3/22/2012 Physician Netherlands
Primary
Secondary
Concomitant
Pharyngitis Life Threatening 4/27/2009 61 Male 209 lb 3/27/2012 Physician Sweden
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/20/2012 55 Male 179 lb 3/28/2012 Physician Netherlands
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/30/2011 50 Female 274 lb 5/4/2012 Physician Canada
Primary
Concomitant
Pulmonary Embolism Life Threatening 7/30/2011 50 Female 274 lb 5/14/2012 Physician Canada
Primary
Concomitant
Sepsis Life Threatening 3/24/2012 70 Female 212 lb 5/15/2012 Physician Germany
Primary
Concomitant

Drug Data