Cyclophosphamide combined with Granulocyte Colony Stimulating Factor

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cardiac Failure Congestive Hospitalization 2/8/2005 18 Female 128 lb 1/10/2006 Physician United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 38 Female 1/20/2010 Consumer United Kingdom
Primary
Secondary
Pyrexia Hospitalization 12/10/2009 Male 150 lb 2/16/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Death 2/18/2010 Physician Italy
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 2/18/2010 Physician Italy
Primary
Secondary
Concomitant
Septic Shock Death 2/18/2010 Physician Italy
Primary
Secondary
Concomitant
Septic Shock Death 2/19/2010 Physician Italy
Primary
Secondary
Concomitant
Diverticulitis Death 2/19/2010 Physician Italy
Primary
Secondary
Concomitant
Sepsis Death 17 Male 2/23/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Death 13 Female 2/23/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Tremor Life Threatening 12/3/2009 Male 3/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/1/2007 1 Male 18 lb 3/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 3/3/2010 Germany
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4/27/2009 3/3/2010 Physician France
Primary
Concomitant
Tachycardia Other Serious 3/5/2010 Germany
Primary
Secondary
Concomitant
Bronchospasm Other Serious 3/5/2010 Germany
Primary
Secondary
Concomitant
Cardiac Failure Death 3/9/2010 Physician Germany
Primary
Secondary
Concomitant
Tuberculosis Other Serious 3/10/2010 Physician Germany
Primary
Secondary
Concomitant
Pancytopenia Death 3/4/2010 Physician Germany
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 12/10/2009 Male 150 lb 3/11/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 51 Female 3/16/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Lymphocytosis Other Serious 54 Male 3/17/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 12/10/2009 Male 143 lb 3/17/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting 42 Female 3/15/2010 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 51 Female 3/24/2010 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/7/2010 Male 143 lb 3/25/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Hospitalization 3/10/2010 Male 141 lb 3/25/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Fat Embolism Hospitalization 22 Male 3/26/2010 Greece
Primary
Secondary
Blood Creatinine Increased Other Serious 73 Female 3/26/2010 Physician Italy
Primary
Secondary
Concomitant
Diverticulitis Death 12/15/2006 67 Male 3/26/2010 Physician Italy
Primary
Secondary
Concomitant
Septic Shock Life Threatening 3/16/2007 57 Male 3/26/2010 Physician Italy
Primary
Secondary
Concomitant
Septic Shock Death 6/26/2007 76 Male 3/26/2010 Physician Italy
Primary
Secondary
Concomitant
Muscular Weakness Life Threatening 22 Male 3/26/2010 Other Health Professional Greece
Primary
Secondary
Thrombocytopenia Life Threatening 12/8/2009 11 Male 82 lb 4/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Hospitalization 3/10/2010 65 Male 141 lb 4/6/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 43 Female 4/9/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 1/7/2010 76 Male 143 lb 4/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/1/2007 1 Male 18 lb 4/23/2010 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 1/7/2010 76 Male 154 lb 5/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Headache Other Serious 43 Male 5/11/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Off Label Use Other Serious 5 Male 5/14/2010 Other Health Professional China
Primary
Secondary
Concomitant
Stem Cell Transplant Other Serious 5/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2008 5 Male 5/21/2010 Other Health Professional China
Primary
Concomitant
Pyrexia Other Serious 5/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 5/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death Unknown 5/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/1/2007 1 Male 18 lb 6/15/2010 Lawyer United States
Primary
Concomitant
Pneumonia Death 11/4/2007 46 Male 6/23/2010 Physician Italy
Primary
Secondary
Concomitant
Diverticulitis Death 12/15/2006 63 Male 6/23/2010 Physician Italy
Primary
Secondary
Concomitant
Escherichia Infection Hospitalization 5/28/2010 84 Female 6/22/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Death 7/1/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Death 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Death 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 11/22/2009 14 Male 165 lb 7/2/2010 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 6/22/2010 60 Female 7/9/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Life Threatening 11/22/2009 14 Male 165 lb 8/3/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 4/27/2009 8/5/2010 Physician France
Primary
Concomitant
Pneumonia Life Threatening 11/22/2009 14 Male 165 lb 8/11/2010 Physician United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 8/27/2010 Physician Korea, Republic Of
Primary
Secondary
Thrombocytopenia Other Serious 8/30/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 4/20/2010 1 Male 15 lb 9/8/2010 Physician United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 44 Male 9/9/2010 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 3/23/2010 76 Male 159 lb 9/9/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiomegaly Death 6/22/2010 60 Female 9/20/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/1/2007 1 Male 18 lb 10/11/2010 Lawyer United States
Primary
Concomitant
Death Death 10/26/2010 Physician Italy
Primary
Secondary
Concomitant
Death Death 10/26/2010 Physician Italy
Primary
Secondary
Concomitant
Death Death 10/26/2010 Physician Italy
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/8/2009 11 Male 82 lb 10/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Bone Pain Hospitalization 4/27/2010 77 Female 115 lb 11/29/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/1/2007 1 Male 18 lb 12/2/2010 Lawyer United States
Primary
Concomitant
Tumour Haemorrhage Hospitalization 11/1/2010 37 Male 198 lb 12/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Bone Pain Hospitalization 2/16/2010 77 Female 115 lb 12/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Multi-organ Failure Death 7/1/2007 1 Male 18 lb 1/27/2011 Physician United States
Primary
Concomitant
Haemorrhage Other Serious 3/1/2011 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 3/1/2011 Physician United States
Primary
Secondary
Concomitant
Ileus Other Serious 3/1/2011 Physician United States
Primary
Secondary
Concomitant
Pyrexia Death 3/2/2011 Physician Spain
Primary
Secondary
Concomitant
Pancytopenia Other Serious 16 Male 3/31/2011 Physician France
Primary
Secondary
Concomitant
Pneumonia Fungal Other Serious 34 Female 3/31/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Metastasis Death 4/4/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Engraftment Syndrome Other Serious 4/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Agranulocytosis Other Serious 0 Male 4/6/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/6/2011 Other Health Professional Austria
Primary
Secondary
Concomitant
Fusarium Infection Other Serious 4/6/2011 Other Health Professional Austria
Primary
Secondary
Concomitant
Enterobacter Infection Other Serious 4/6/2011 Other Health Professional Austria
Primary
Secondary
Concomitant
Enteritis Other Serious 4/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Death 4/8/2011 Physician United States
Primary
Secondary
Concomitant
Myocarditis Death 4/13/2011 Other Health Professional India
Primary
Secondary
Concomitant
Hepatic Failure Death Female 4/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 34 Female 4/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Enteritis Other Serious 4/20/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Epstein-barr Virus Infection Other Serious 4/20/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutropenic Sepsis Death 34 Female 4/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transfusion Reaction Other Serious 9/9/2001 40 5/5/2011 Consumer United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 5/25/2011 Physician Japan
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 6/7/2011 Physician Japan
Primary
Secondary
Concomitant
Ureteric Obstruction Hospitalization 4/28/2011 63 Male 238 lb 6/22/2011 Physician United Kingdom
Primary
Secondary
Vomiting Hospitalization 7/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Other Serious 17 Male 7/14/2011 Other Health Professional China
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 43 Male 7/14/2011 Other Health Professional China
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 32 Female 7/14/2011 Other Health Professional China
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 38 Male 7/14/2011 Other Health Professional China
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 18 Male 7/14/2011 Physician China
Primary
Concomitant
Chronic Graft Versus Host Disease Other Serious 32 Male 7/14/2011 Other Health Professional China
Primary
Concomitant
Delirium Hospitalization 7/30/2011 65 Female 216 lb 8/19/2011 Consumer United Kingdom
Primary
Secondary
Serum Sickness Other Serious 7/24/2009 Female 99 lb 8/24/2011 Physician China
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 39 Female 12/29/2011 Physician Japan
Primary
Secondary
Concomitant
Radiation Necrosis Other Serious 58 Male 5/1/2012 Other Health Professional United States
Primary
Secondary
Death Death 5/4/2012 Other Health Professional France
Primary
Secondary
Treatment Related Secondary Malignancy Hospitalization 5/7/2012 Other Health Professional France
Primary
Secondary
Septic Shock Death 5/10/2012 Other Health Professional France
Primary
Secondary
Myelodysplastic Syndrome Other Serious 5/10/2012 Other Health Professional France
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 5/10/2012 Other Health Professional France
Primary
Secondary
Concomitant
Cholestasis Other Serious 5/10/2012 Other Health Professional France
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 5/10/2012 Other Health Professional France
Primary
Secondary
Concomitant
Hypoxia Other Serious 5/10/2012 Other Health Professional China
Primary
Secondary
Concomitant
Skin Cancer Hospitalization 5/16/2012 Other Health Professional France
Primary
Secondary
Pneumonitis Death 17 Male 5/22/2012 Other Health Professional Portugal
Primary
Concomitant
Interacting
Fatigue Other Serious Female 5/29/2012 Other Health Professional United States
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 5/30/2012 Other Health Professional France
Primary
Secondary
Epstein-barr Virus Infection Other Serious Male 6/14/2012 Physician Italy
Primary
Secondary
Organising Pneumonia Death 67 Male 6/25/2012 Other Health Professional Australia
Primary
Concomitant
Toxicity To Various Agents Death 6/27/2012 Physician France
Primary
Secondary
Acute Myeloid Leukaemia Hospitalization 9/19/2012 Other Health Professional Fi
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 9/21/2012 Other Health Professional Fi
Primary
Secondary
Concomitant
Vomiting Other Serious 7 Female 9/27/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Neutropenia Hospitalization Female 10/10/2012 Physician Us
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Death 7 Male 10/12/2012 Other Health Professional Cn
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 33 Male 10/16/2012 Other Health Professional Cn
Primary
Concomitant
Organ Failure Death 30 Male 10/17/2012 Other Health Professional Cn
Primary
Concomitant
Interstitial Lung Disease Other Serious 9 Male 64 lb 10/17/2012 Other Health Professional Cn
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 6 Male 49 lb 10/17/2012 Other Health Professional Cn
Primary
Secondary
Concomitant
Thalassaemia Beta Other Serious 7 Male 49 lb 10/17/2012 Other Health Professional Cn
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Other Serious 24 Male 10/19/2012 Other Health Professional Cn
Primary
Concomitant
Graft Versus Host Disease In Skin Other Serious 24 Male 10/19/2012 Other Health Professional Cn
Primary
Secondary
Concomitant
Pneumonia Legionella Death 10/25/2012 Other Health Professional It
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 10/26/2012 Other Health Professional It
Primary
Concomitant
Pericarditis Other Serious 10/26/2012 Other Health Professional It
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 11/6/2012 Consumer De
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 10/20/2011 51 Female 80 lb 12/3/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Infection Hospitalization 5/3/2012 74 Male 209 lb 11/15/2012 Physician Dk
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 12/11/2012 Physician De
Primary
Secondary
Concomitant
Sepsis Death 12/13/2012 Other Health Professional Ca
Primary
Secondary
Vomiting Other Serious 12/19/2012 Physician De
Primary
Secondary
Myelodysplastic Syndrome Other Serious 12/19/2012 Physician De
Primary
Secondary
Ill-defined Disorder Other Serious 12/20/2012 Physician De
Primary
Secondary
Myelodysplastic Syndrome Other Serious 12/20/2012 Physician De
Primary
Secondary
Concomitant
Neutropenia Life Threatening 11 Female 12/21/2012 Other Health Professional Ca
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 11/13/2012 Other Health Professional Ca
Primary
Secondary

Drug Data