Cyclophosphamide combined with Fludarabine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Death 36 Female 1/5/2006 United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 47 Male 1/19/2006 Physician United States
Primary
Concomitant
Subacute Endocarditis Other Serious 9/1/2004 82 Male 157 lb 1/18/2006 Other Health Professional Germany
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 64 Male 1/25/2006 Other Health Professional Germany
Primary
Secondary
Hepatitis Other Serious 47 Male 3/7/2006 Physician France
Primary
Concomitant
Platelet Count Decreased Hospitalization 12/25/2005 64 Female 121 lb 3/17/2006 Other Health Professional France
Primary
Secondary
Concomitant
Sputum Culture Positive Hospitalization 1/25/2006 73 Male 130 lb 3/17/2006 Other Health Professional Thailand
Primary
Secondary
Viral Infection Other Serious 8/1/2005 52 Female 126 lb 3/21/2006 Physician France
Primary
Concomitant
Tuberculosis Other Serious 6/9/2005 69 Male 104 lb 3/21/2006 Other Health Professional France
Primary
Secondary
Concomitant
Trichosporon Infection Other Serious 1/1/2004 30 Male 3/29/2006 Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 9/8/2005 64 Female 3/28/2006 Physician Austria
Primary
Secondary
Tumour Lysis Syndrome Life Threatening 3/10/2006 62 Male 4/4/2006 Consumer United States
Primary
Secondary
Vomiting Hospitalization 2/6/2006 59 Male 128 lb 3/30/2006 Physician Germany
Primary
Secondary
Concomitant
Pain Life Threatening 3/8/2006 62 Female 184 lb 3/29/2006 Physician Australia
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/24/2005 75 Male 181 lb 4/3/2006 Physician Spain
Primary
Secondary
Concomitant
Cerebral Toxoplasmosis Hospitalization 2/15/2006 71 Male 4/4/2006 Other Health Professional Belgium
Primary
Secondary
Shock Death 8/2/2005 70 Male 187 lb 4/4/2006 Physician Italy
Primary
Secondary
Concomitant
Sepsis Hospitalization 2/6/2006 59 Male 128 lb 4/5/2006 Physician Germany
Primary
Secondary
Concomitant
Haematuria Hospitalization 3/23/2006 78 Female 4/6/2006 Physician France
Primary
Secondary
Sinus Bradycardia Hospitalization 3/22/2006 67 Female 148 lb 4/10/2006 Physician Italy
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 3/24/2006 69 Male 4/10/2006 Physician Netherlands
Primary
Secondary
Tumour Lysis Syndrome Life Threatening 3/10/2006 62 Male 4/19/2006 Consumer United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/8/2005 70 Male 4/13/2006 Physician Spain
Primary
Secondary
Sinus Headache Hospitalization 1/13/2006 71 Male 176 lb 4/12/2006 Physician Belgium
Primary
Secondary
Concomitant
Agranulocytosis Life Threatening 3/8/2006 62 Female 184 lb 4/13/2006 Physician Australia
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 10/1/2002 64 Male 4/10/2006
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Hospitalization 3/24/2006 69 Male 4/18/2006 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/6/2006 59 Male 128 lb 4/18/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Kyphosis Hospitalization 10/20/2005 4/21/2006 Physician Germany
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 9/8/2005 70 Male 4/24/2006 Other Health Professional Spain
Primary
Secondary
Septic Shock Death 4/7/2006 58 Male 183 lb 4/24/2006 Other Health Professional Belgium
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 4/4/2006 57 Male 192 lb 5/1/2006 Physician Denmark
Primary
Secondary
Concomitant
Septic Shock Death 4/7/2006 58 Male 183 lb 5/1/2006 Physician Belgium
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 7/30/2005 66 Male 203 lb 5/3/2006 Other Health Professional Hungary
Primary
Secondary
Concomitant
Gastric Haemorrhage Death 4/17/2006 70 Female 5/3/2006 Physician Hungary
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 7/26/2005 66 Male 203 lb 5/3/2006 Physician Hungary
Primary
Secondary
Concomitant
Septic Shock Death 4/7/2006 58 Male 183 lb 5/4/2006 Physician Belgium
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Life Threatening 3/10/2006 62 Male 5/9/2006 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Bacterial Other Serious 11/1/2005 61 Male 157 lb 5/3/2006 Physician United States
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 1/28/2006 75 Female 5/12/2006 Consumer United States
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Hospitalization 3/23/2006 Male 5/15/2006 Physician Hungary
Primary
Concomitant
Neutropenia Hospitalization 1/28/2006 75 Female 5/15/2006 Consumer United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Death 75 Female 5/9/2006 Other Health Professional Australia
Primary
Secondary
Thrombin Time Prolonged Life Threatening 9/7/2005 63 Male 175 lb 5/9/2006 Physician Hungary
Primary
Secondary
Concomitant
Neutropenia Hospitalization 2/1/2006 63 Male 187 lb 5/16/2006 Physician Germany
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 4/3/2006 69 Male 220 lb 5/16/2006 Physician France
Primary
Secondary
Concomitant
Viraemia Death 4/7/2006 58 Male 183 lb 5/17/2006 Physician Belgium
Primary
Secondary
Concomitant
Wheezing Other Serious 6/9/2005 69 Male 104 lb 5/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 4/4/2006 57 Male 192 lb 5/19/2006 Other Health Professional Denmark
Primary
Secondary
Concomitant
Superinfection Life Threatening 2/15/2003 76 Male 214 lb 5/19/2006 Physician France
Primary
Concomitant
Thrombocytopenia Hospitalization 11/24/2005 75 Male 181 lb 5/23/2006 Physician Spain
Primary
Secondary
Concomitant
Left Ventricular Failure Death 4/17/2006 70 Female 5/23/2006 Physician Hungary
Primary
Secondary
Concomitant
Viraemia Death 4/7/2006 58 Male 183 lb 5/23/2006 Physician Belgium
Primary
Secondary
Concomitant
Headache Hospitalization 4/21/2006 45 Male 5/30/2006 Consumer United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 8/19/2005 74 Female 123 lb 5/25/2006 Physician Belgium
Primary
Secondary
Concomitant
Hepatitis Other Serious 47 Male 5/25/2006 Physician France
Primary
Concomitant
Aplasia Pure Red Cell Hospitalization 3/23/2006 Male 6/7/2006 Physician Hungary
Primary
Concomitant
Subcutaneous Abscess Hospitalization 2/1/2006 63 Male 187 lb 5/31/2006 Physician Germany
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 5/2/2006 69 Male 220 lb 5/31/2006 Physician France
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Death 8/21/2005 67 Female 159 lb 6/1/2006 Physician Spain
Primary
Secondary
Concomitant
Soft Tissue Necrosis Hospitalization 2/1/2006 63 Male 187 lb 6/2/2006 Physician Germany
Primary
Secondary
Concomitant
Immunodeficiency Life Threatening 11/23/2005 6/2/2006 Physician Spain
Primary
Secondary
Respiratory Failure Death 9/7/2005 73 Male 171 lb 6/5/2006 Spain
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/18/2005 65 Female 159 lb 6/2/2006 Other Health Professional Spain
Primary
Secondary
Agranulocytosis Hospitalization 11/22/2005 42 Female 6/5/2006 Physician Spain
Primary
Secondary
Febrile Neutropenia Hospitalization 3/27/2005 66 Female 153 lb 6/5/2006 Physician Spain
Primary
Secondary
White Blood Cells Urine Positive Death 4/17/2006 70 Female 6/5/2006 Physician Hungary
Primary
Secondary
Concomitant
Sinusitis Hospitalization 68 Male 196 lb 6/5/2006 Physician Germany
Primary
Secondary
Concomitant
Aplasia Hospitalization 5/27/2006 68 Female 159 lb 6/6/2006 Physician France
Primary
Secondary
Streptococcal Infection Hospitalization 6/7/2006 Male 135 lb 6/8/2006 United States
Primary
Secondary
Concomitant
Migraine Other Serious 5/19/2006 45 Male 194 lb 6/19/2006 Other Health Professional Australia
Primary
Secondary
Febrile Neutropenia Hospitalization 4/18/2005 65 Female 159 lb 6/12/2006 Other Health Professional Spain
Primary
Secondary
Aplasia Hospitalization 5/27/2006 68 Female 159 lb 6/12/2006 Physician United States
Primary
Secondary
Subcutaneous Abscess Hospitalization 2/1/2006 63 Male 187 lb 6/12/2006 Physician Germany
Primary
Secondary
Concomitant
Headache Hospitalization 4/21/2006 45 Male 6/19/2006 Consumer United States
Primary
Secondary
Concomitant
Photophobia Hospitalization 4/21/2006 45 Male 172 lb 6/16/2006 Physician Australia
Primary
Secondary
Concomitant
Agranulocytosis Other Serious 5/22/2006 49 168 lb 6/15/2006 Other Health Professional Poland
Primary
Secondary
Polyuria Other Serious 5/19/2006 45 Male 184 lb 6/19/2006 Physician Australia
Primary
Secondary
Concomitant
Oral Infection Other Serious 4/18/2005 58 Female 168 lb 6/20/2006 Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/10/2004 75 Female 6/20/2006 Physician Sweden
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/22/2006 49 168 lb 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 1/13/2006 71 Male 176 lb 6/26/2006 Physician Belgium
Primary
Secondary
Concomitant
Memory Impairment Hospitalization 2/15/2006 71 Male 6/26/2006 Physician Belgium
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 2/11/2006 62 Male 126 lb 6/27/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Leukocyturia Hospitalization 5/27/2006 68 Female 159 lb 6/27/2006 Other Health Professional France
Primary
Secondary
Hepatotoxicity Hospitalization 4/4/2006 57 Male 192 lb 6/28/2006 Physician Denmark
Primary
Secondary
Concomitant
Migraine Other Serious 5/19/2006 45 Male 194 lb 7/6/2006 Other Health Professional Australia
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 2/11/2006 62 Male 126 lb 6/30/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2005 61 Male 157 lb 7/6/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Bacterial Other Serious 11/1/2005 61 Male 157 lb 7/6/2006 Physician United States
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 59 Male 135 lb 7/6/2006 United Kingdom
Primary
Concomitant
Nervous System Disorder Other Serious 59 Male 135 lb 7/6/2006 United Kingdom
Primary
Concomitant
Haemolysis Hospitalization 5/15/2005 69 Female 123 lb 7/6/2006 Physician Germany
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 5/28/2006 Male 7/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Pyrexia Hospitalization 5/22/2006 49 Unknown 168 lb 7/10/2006 Physician Poland
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 62 Male 7/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Superficial Spreading Melanoma Stage Ii Other Serious 59 Male 7/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 61 Male 7/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Neoplasm Excision Other Serious 53 Male 7/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 4/18/2005 65 Female 159 lb 7/10/2006 Other Health Professional Spain
Primary
Secondary
Staphylococcal Infection Death 8/8/2005 67 Female 159 lb 7/10/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 4/4/2006 57 Male 192 lb 7/12/2006 Other Health Professional Denmark
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/11/2006 62 Male 126 lb 7/13/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 2/15/2006 71 Male 7/17/2006 Other Health Professional Belgium
Primary
Secondary
Concomitant
Nonspecific Reaction Hospitalization 6/17/2006 56 Male 187 lb 7/18/2006 Physician Spain
Primary
Secondary
Staphylococcal Infection Hospitalization 3/27/2005 66 Female 153 lb 7/18/2006 Physician Spain
Primary
Secondary
Concomitant
Viral Upper Respiratory Tract Infection Death 9/7/2005 73 Male 171 lb 7/21/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Viral Infection Other Serious 1/1/2003 16 Female 7/28/2006 United Kingdom
Primary
Concomitant
Soft Tissue Necrosis Hospitalization 7/17/2006 70 Male 220 lb 7/31/2006 Other Health Professional Canada
Primary
Secondary
Febrile Neutropenia Hospitalization 5/2/2006 69 Male 220 lb 7/31/2006 Physician France
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 5/27/2006 68 Female 159 lb 7/31/2006 Physician France
Primary
Secondary
Headache Hospitalization 4/21/2006 45 Male 8/7/2006 Consumer United States
Primary
Secondary
Concomitant
Pain Life Threatening 3/8/2006 62 Female 184 lb 8/1/2006 Physician Australia
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 6/12/2006 76 Male 137 lb 8/2/2006 Physician Israel
Primary
Secondary
Toxoplasmosis Hospitalization 5/11/2006 68 Male 8/8/2006 Physician Spain
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 5/19/2006 45 Male 184 lb 8/10/2006 Australia
Primary
Secondary
Concomitant
Ischaemic Stroke Life Threatening 4/30/2006 57 Female 8/21/2006 Other Health Professional Spain
Primary
Concomitant
Pyrexia Other Serious 5/23/2006 49 Female 106 lb 8/22/2006 Physician Spain
Primary
Secondary
Concomitant
Immunosuppression Life Threatening 6/7/2006 49 Male 9/1/2006 Consumer France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/17/2006 Female 9/18/2006 Other Health Professional United States
Primary
Secondary
Migraine Other Serious 5/18/2006 45 Male 194 lb 9/22/2006 Other Health Professional Australia
Primary
Secondary
Migraine Other Serious 5/18/2006 45 Male 184 lb 9/26/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Immunosuppression Life Threatening 6/7/2006 49 Male 187 lb 10/3/2006 Consumer France
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 55 10/5/2006 Physician Spain
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 62 Female 10/13/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Viral Infection Life Threatening 4/1/2006 62 Female 10/13/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/1/1999 54 Male 10/13/2006
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Death 62 Female 10/11/2006 United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 54 Male 10/19/2006 Other Health Professional France
Primary
Secondary
Graft Versus Host Disease Other Serious 61 Female 10/19/2006
Primary
Secondary
Malignant Melanoma Other Serious 59 Male 10/19/2006
Primary
Secondary
Squamous Cell Carcinoma Other Serious 62 Male 10/19/2006
Primary
Secondary
Squamous Cell Carcinoma Other Serious 45 Male 10/19/2006
Primary
Secondary
Malignant Melanoma Other Serious 53 Male 10/19/2006
Primary
Secondary
Squamous Cell Carcinoma Other Serious 61 Male 10/19/2006
Primary
Secondary
Crossmatch Incompatible Other Serious 8/1/2006 76 Male 10/12/2006 Physician Germany
Primary
Concomitant
Thrombocytopenia Hospitalization 11/23/2006 68 Male 195 lb 11/30/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 56 Female 12/9/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/30/2006 Male 231 lb 12/11/2006 Physician United States
Primary
Concomitant
Haemolytic Anaemia Other Serious 10/19/2006 70 Male 12/11/2006 Consumer United States
Primary
Secondary
Concomitant
Mucous Stools Other Serious 4 Female 12/14/2006 Japan
Primary
Concomitant
Haemolysis Other Serious 8/1/2006 76 Male 11/22/2006 Physician Germany
Primary
Concomitant
Haemolysis Hospitalization 55 Male 12/19/2006 Other Health Professional United States
Primary
Secondary
Mucous Stools Other Serious 4 Female 1/3/2007 Japan
Primary
Concomitant
Tonic Convulsion Other Serious 12/22/2005 10 Male 61 lb 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Death 25 Male 1/22/2007 Other Health Professional Spain
Primary
Secondary
Concomitant
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 1/30/2007 Japan
Primary
Concomitant
Vasculitis Death 15 Male 2/6/2007 Physician Canada
Primary
Secondary
Concomitant
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 2/8/2007 Japan
Primary
Concomitant
Viral Dna Test Positive Other Serious 7/11/2004 15 Male 73 lb 2/8/2007 Japan
Primary
Concomitant

Drug Data