Cyclophosphamide combined with Fludarabine Phosphate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Neutropenia Other Serious 8/1/2005 55 Female 12/22/2005 Physician France
Primary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 12/25/2005 64 Female 121 lb 1/10/2006 Physician France
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 11/19/2005 78 Female 191 lb 1/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Hospitalization 12/29/2005 40 Male 170 lb 1/12/2006 Physician Australia
Primary
Secondary
Concomitant
Productive Cough Other Serious 10/18/2004 Male 183 lb 1/13/2006 United States
Primary
Secondary
Paralysis Other Serious 10/1/2005 66 Male 168 lb 1/13/2006 Physician Germany
Primary
Concomitant
Thrombocytopenia Hospitalization 1/2/2006 75 Male 181 lb 1/13/2006 Physician Spain
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Infection Other Serious 12/16/2005 Male 160 lb 1/13/2006 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/17/2004 Female 132 lb 1/17/2006 United States
Primary
Secondary
Pyrexia Other Serious 10/2/2005 Male 160 lb 1/18/2006 United States
Primary
Secondary
Concomitant
Parotitis Required Intervention 1/1/2005 75 Male 1/23/2006 Physician Israel
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/1/2004 75 Female 130 lb 1/24/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/1/2004 75 Female 130 lb 1/24/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Weight Decreased Death 6 Male 1/27/2006 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/2/2006 75 Male 181 lb 1/27/2006 Physician Spain
Primary
Secondary
Concomitant
Septic Shock Death 12/28/2005 64 Male 1/30/2006 Germany
Primary
Concomitant
Pulmonary Congestion Death 2/24/2005 68 Female 1/25/2006 Other Health Professional Belgium
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 10/8/2004 68 Female 1/30/2006 Other Health Professional Belgium
Primary
Secondary
Concomitant
Tremor Hospitalization 1/1/2006 56 207 lb 2/2/2006 Physician Czech Republic
Primary
Secondary
Rales Other Serious 55 Female 2/9/2006 Physician France
Primary
Concomitant
Tuberculosis Other Serious 6/9/2005 69 Male 104 lb 2/6/2006 France
Primary
Secondary
Concomitant
Tremor Hospitalization 1/1/2006 56 207 lb 2/10/2006 Physician Czech Republic
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Hospitalization 12/29/2005 40 Male 170 lb 2/14/2006 Physician Australia
Primary
Secondary
Concomitant
Lymphoma Transformation Hospitalization 9/1/2005 57 Male 2/15/2006 United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 8/5/2005 52 Male 168 lb 2/16/2006 Physician Belgium
Primary
Secondary
Concomitant
Transplant Life Threatening 7/2/2005 59 Male 139 lb 2/22/2006 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/6/2006 59 Male 128 lb 2/23/2006 Physician Germany
Primary
Secondary
Concomitant
Metastases To Peritoneum Life Threatening 7/2/2005 59 Male 2/28/2006 France
Primary
Secondary
Trichosporon Infection Other Serious 1/1/2004 30 Male 3/9/2006 Japan
Primary
Concomitant
Peritoneal Carcinoma Life Threatening 7/2/2005 59 Male 139 lb 3/6/2006 Physician France
Primary
Secondary
Concomitant
Respiratory Failure Death 5/9/2005 65 Male 2/28/2006 Physician United States
Primary
Concomitant
Metastases To Peritoneum Life Threatening 7/2/2005 59 Male 139 lb 3/16/2006 Physician France
Primary
Secondary
Concomitant
Ventricular Arrhythmia Hospitalization 10/8/2003 76 Male 225 lb 4/17/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Life Threatening 3/10/2006 62 Male 120 lb 4/17/2006 Physician New Zealand
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/30/2005 68 Male 4/19/2006 Physician France
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Life Threatening 3/10/2006 62 Male 120 lb 5/10/2006 Physician New Zealand
Primary
Secondary
Concomitant
Myocardial Infarction Death 12/19/2005 71 Male 5/10/2006 Consumer Canada
Primary
Secondary
Aplasia Pure Red Cell Other Serious 55 5/23/2006 Physician Spain
Primary
Concomitant
Sensory Loss Other Serious 1/1/2003 70 Male 5/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Photophobia Hospitalization 4/21/2006 43 Male 172 lb 5/30/2006 Other Health Professional Australia
Primary
Secondary
Refractory Anaemia Other Serious 7/1/2003 50 6/2/2006 Physician United Kingdom
Primary
Concomitant
Venous Thrombosis Limb Other Serious 4/20/2006 59 6/2/2006 Other Health Professional Germany
Primary
Secondary
Acute Myeloid Leukaemia Death 2/1/2004 39 6/2/2006 Physician United Kingdom
Primary
Concomitant
Refractory Anaemia With An Excess Of Blasts Death 1/1/2002 60 6/2/2006 Physician United Kingdom
Primary
Concomitant
Refractory Anaemia Other Serious 5/1/2000 55 Unknown 6/2/2006 Physician United Kingdom
Primary
Concomitant
Refractory Anaemia Death 11/1/2004 Unknown 6/2/2006 Physician United Kingdom
Primary
Concomitant
Tumour Haemorrhage Death 2/24/2005 68 Female 6/6/2006 Physician Belgium
Primary
Secondary
Concomitant
Pneumonia Required Intervention 64 Male 6/16/2006 Physician Germany
Primary
Concomitant
Squamous Cell Carcinoma Of Skin Other Serious 61 Male 7/15/2006 Physician United States
Primary
Secondary
Concomitant
Photosensitivity Reaction Other Serious 53 Male 7/15/2006 Physician United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 45 Male 7/15/2006 Physician United States
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious 61 Female 7/14/2006 Physician United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 62 Male 7/14/2006 Physician United States
Primary
Secondary
Concomitant
Superficial Spreading Melanoma Stage Ii Other Serious 59 Male 7/15/2006 Physician United States
Primary
Concomitant
Troponin I Increased Hospitalization 8/1/2006 Male 181 lb 8/1/2006 United States
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Hospitalization 9/1/2005 Male 220 lb 8/8/2006 Physician Germany
Primary
Secondary
Neutropenia Hospitalization 7/14/2006 73 Male 163 lb 8/10/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/14/2005 54 Female 181 lb 8/14/2006 Other Health Professional Germany
Primary
Secondary
Staphylococcal Bacteraemia Death 8/8/2005 67 Female 159 lb 8/14/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/11/2006 62 Male 126 lb 8/15/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Hepatitis B Hospitalization 4/4/2006 57 Male 192 lb 8/15/2006 Other Health Professional Denmark
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 9/19/2005 74 Female 123 lb 8/16/2006 Physician Belgium
Primary
Secondary
Concomitant
Septic Shock Death 7/24/2006 58 Male 126 lb 8/18/2006 Other Health Professional Spain
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/19/2005 74 Female 123 lb 8/22/2006 Physician Belgium
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 8/1/2006 56 Male 173 lb 8/22/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 8/19/2005 67 Female 143 lb 8/22/2006 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/1/2005 Male 220 lb 8/25/2006 Physician Germany
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 8/19/2005 67 Female 143 lb 8/31/2006 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/22/2006 49 168 lb 9/5/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/15/2006 71 Male 9/11/2006 Physician Belgium
Primary
Secondary
Concomitant
Pancytopenia Other Serious 9/1/2003 Female 9/8/2006
Primary
Secondary
Thrombosis Other Serious 4/20/2006 59 9/18/2006 Other Health Professional Germany
Primary
Secondary
Pancytopenia Other Serious Female 9/18/2006 Other Health Professional Ireland
Primary
Secondary
Febrile Neutropenia Hospitalization 6/17/2006 40 Male 137 lb 9/18/2006 Physician Spain
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/3/2006 67 Female 143 lb 9/26/2006 Physician Germany
Primary
Secondary
Concomitant
Neutropenia Hospitalization 7/14/2006 73 Male 163 lb 9/26/2006 Physician Poland
Primary
Secondary
Concomitant
Subcutaneous Abscess Hospitalization 2/1/2006 63 Male 187 lb 9/25/2006 Physician Germany
Primary
Secondary
Concomitant
Photosensitivity Reaction Hospitalization 3/1/2006 59 Male 9/25/2006 Consumer France
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 3/22/2006 67 Female 148 lb 9/28/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 9/1/2006 69 Female 9/27/2006 Other Health Professional Spain
Primary
Secondary
Vomiting Hospitalization 2/7/2006 59 Male 128 lb 9/27/2006 Physician Germany
Primary
Secondary
Concomitant
Immunosuppression Other Serious 6/7/2006 49 Male 187 lb 9/29/2006 Physician France
Primary
Secondary
Soft Tissue Necrosis Hospitalization 7/17/2006 70 Male 220 lb 9/29/2006 Physician Canada
Primary
Secondary
Pyrexia Death 7/11/2006 60 Female 97 lb 10/9/2006 Other Health Professional Hungary
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 62 Female 10/9/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 59 Male 10/12/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 4/18/2005 58 Female 168 lb 10/13/2006 Germany
Primary
Secondary
Concomitant
Granulocytopenia Hospitalization 11/23/2004 63 Male 179 lb 10/17/2006 Other Health Professional Hungary
Primary
Secondary
Concomitant
Malignant Melanoma Other Serious 53 Male 10/12/2006 United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 62 Female 10/20/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/14/2006 73 Male 163 lb 10/23/2006 Physician Poland
Primary
Secondary
Concomitant
Streptococcal Infection Hospitalization 8/18/2006 49 Male 176 lb 10/24/2006 Physician Australia
Primary
Secondary
Concomitant
Polyarthritis Other Serious 61 Female 10/24/2006 Physician France
Primary
Concomitant
Pyrexia Death 7/11/2006 60 Female 97 lb 10/25/2006 Physician Hungary
Primary
Secondary
Concomitant
Bronchopulmonary Aspergillosis Other Serious 5/23/2006 49 Female 106 lb 11/1/2006 Physician Spain
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 62 Female 11/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Fungal Hospitalization 3/29/2006 71 Male 176 lb 11/10/2006 Physician Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 7/1/2006 69 Male 220 lb 11/14/2006 Physician France
Primary
Secondary
Concomitant
Respiratory Failure Death 9/16/2006 70 Male 11/15/2006 Physician Canada
Primary
Secondary
Neoplasm Malignant Other Serious 7/1/2006 69 Male 220 lb 11/14/2006 Physician France
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 7/1/2006 69 Male 220 lb 11/15/2006 Physician France
Primary
Secondary
Concomitant
Pyrexia Death 7/11/2006 60 Female 97 lb 11/16/2006 Physician Hungary
Primary
Secondary
Concomitant
Soft Tissue Necrosis Hospitalization 7/17/2006 70 Male 220 lb 11/20/2006 Physician Canada
Primary
Secondary
Colon Cancer Other Serious 11/2/2004 78 Female 143 lb 11/20/2006 Physician France
Primary
Secondary
Concomitant
Refractory Anaemia With An Excess Of Blasts Other Serious 40 Female 11/22/2006 Physician Australia
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 60 Female 11/22/2006 Physician Australia
Primary
Secondary
Myelodysplastic Syndrome Other Serious 65 Male 11/22/2006 Physician Australia
Primary
Secondary
Pancytopenia Other Serious 66 Female 11/22/2006 Physician Australia
Primary
Secondary
Myelodysplastic Syndrome Other Serious 53 Female 11/22/2006 Physician Australia
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 53 Male 11/22/2006 Physician Australia
Primary
Secondary
Chronic Myelomonocytic Leukaemia Other Serious 56 Male 11/22/2006 Physician Australia
Primary
Secondary
Refractory Anaemia With An Excess Of Blasts Other Serious 66 Female 11/22/2006 Physician Australia
Primary
Secondary
Refractory Anaemia With An Excess Of Blasts Other Serious 52 Female 11/22/2006 Physician Australia
Primary
Secondary
Myelodysplastic Syndrome Other Serious 69 Male 11/22/2006 Physician Australia
Primary
Secondary
Neoplasm Malignant Other Serious 7/1/2006 69 Male 220 lb 11/28/2006 Physician France
Primary
Secondary
Concomitant
Pancytopenia Other Serious Female 11/29/2006 Physician Ireland
Primary
Secondary
Tumour Lysis Syndrome Life Threatening 11/17/2006 67 Male 180 lb 11/29/2006 Physician Austria
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Life Threatening 12/29/2005 63 Female 12/1/2006 Other Health Professional Canada
Primary
Secondary
Neoplasm Malignant Other Serious 7/1/2006 69 Male 220 lb 12/1/2006 Physician France
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 12/7/2006 Physician Italy
Primary
Secondary
Myelodysplastic Syndrome Other Serious 12/7/2006 Physician Italy
Primary
Secondary
Myelodysplastic Syndrome Other Serious 12/7/2006 Physician Italy
Primary
Secondary
Tumour Lysis Syndrome Life Threatening 11/17/2006 67 Male 180 lb 12/12/2006 Physician Austria
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 10 Male 12/13/2006 Physician Japan
Primary
Concomitant
Soft Tissue Necrosis Hospitalization 7/17/2006 70 Male 220 lb 12/20/2006 Physician Canada
Primary
Secondary
White Blood Cell Count Increased Hospitalization 3/10/2005 62 Female 110 lb 12/20/2006 Physician Germany
Primary
Secondary
Concomitant
Nausea Hospitalization 4/1/2006 57 Male 12/21/2006 Lawyer Denmark
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Life Threatening 12/15/2006 67 Male 180 lb 12/22/2006 Physician Austria
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 9/19/2005 74 Female 123 lb 12/28/2006 Physician Belgium
Primary
Secondary
Concomitant
Rash Other Serious 3/2/2006 64 Male 1/8/2007 Other Health Professional France
Primary
Secondary
Concomitant
Nausea Hospitalization 4/1/2006 57 Male 1/8/2007 Lawyer Denmark
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 12/22/2005 10 Male 61 lb 1/17/2007 Physician Japan
Primary
Secondary
Concomitant
Transitional Cell Carcinoma Hospitalization 1/16/2007 65 Male 2/15/2007 Other Health Professional Germany
Primary
Secondary
Ventricular Tachycardia Hospitalization 56 Male 2/19/2007 Physician Japan
Primary
Secondary
Pyrexia Life Threatening 2/5/2007 72 Male 182 lb 2/21/2007 Physician Russian Federation
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 6/1/2006 77 Male 181 lb 2/22/2007 Physician Germany
Primary
Concomitant
Brain Abscess Life Threatening 2/16/2007 70 Male 220 lb 3/1/2007 Physician France
Primary
Secondary
Rash Maculo-papular Hospitalization 11/23/2006 51 Male 141 lb 3/8/2007 Physician Germany
Primary
Secondary
Concomitant
Pancytopenia Other Serious Male 3/8/2007 Physician Australia
Primary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 7/3/2006 67 Female 143 lb 3/10/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 6/1/2006 77 Male 181 lb 3/22/2007 Physician Germany
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 12/22/2005 10 Male 61 lb 3/22/2007 Physician Japan
Primary
Secondary
Concomitant
Sinusitis Life Threatening 2/5/2007 72 Male 182 lb 3/28/2007 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 52 Female 4/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Sepsis Other Serious 25 Male 4/6/2007 Other Health Professional Australia
Primary
Secondary
Toxic Epidermal Necrolysis Hospitalization 8/16/2006 71 Female 5/3/2007 Other Health Professional France
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 8/26/2004 Male 183 lb 5/4/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Other Serious 2/6/2006 59 Male 141 lb 5/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/9/2006 66 Female 132 lb 5/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Death 9/19/2006 Female 97 lb 5/11/2007 Physician United Kingdom
Primary
Secondary
Concomitant

Drug Data