Cyclophosphamide combined with Filgrastim

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Therapeutic Agent Toxicity Other Serious 2/1/1999 41 Male 3/6/2006 Physician Germany
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 1/1/2004 6 Male 40 lb 3/10/2006 Physician Japan
Primary
Secondary
Post Procedural Complication Other Serious 2/1/2006 52 Male 3/24/2006 Other Health Professional Germany
Primary
Secondary
Pseudomonas Infection Death 67 Female 10/23/2006 Physician United States
Primary
Concomitant
Peritonitis Death 72 Male 10/23/2006 Physician United States
Primary
Concomitant
Reflux Gastritis Hospitalization 9/15/2006 73 Female 121 lb 12/21/2006 Mexico
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/17/2006 26 Female 12/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Hospitalization 10/22/2006 11 Female 75 lb 1/18/2007 Physician United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 10/17/2006 NotSpecified 1/19/2007 Other Health Professional Norway
Primary
Concomitant
Vaginal Cellulitis Required Intervention 11/17/2006 26 Female 1/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 1/22/2007 5 Female 27 lb 2/7/2007 United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 1/22/2007 5 Female 27 lb 2/15/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 1/22/2007 5 Female 27 lb 2/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 66 Female 3/5/2007
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/31/2007 9 Female 52 lb 3/5/2007 Physician United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 3/30/2007 Other Health Professional Germany
Primary
Secondary
Acute Graft Versus Host Disease Hospitalization 10/20/2006 46 Male 3/26/2007 Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 4/5/2007 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 6/12/2005 Male 146 lb 4/18/2007 Physician United Kingdom
Primary
Secondary
Concomitant
X-ray Gastrointestinal Tract Abnormal Hospitalization 1/22/2007 5 Female 27 lb 4/10/2007 United States
Primary
Secondary
Concomitant
Sopor Other Serious 62 Female 4/21/2007 Physician Switzerland
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 62 Female 5/8/2007 Other Health Professional Switzerland
Primary
Secondary
Vomiting Life Threatening 4/20/2007 9 Female 47 lb 5/3/2007 Physician United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 62 Female 5/5/2007 Physician Switzerland
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 3/1/2007 Male 5/14/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 62 Female 5/18/2007
Primary
Secondary
White Blood Cell Count Abnormal Hospitalization 1/31/2007 9 Female 52 lb 5/17/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Abnormal Hospitalization 1/22/2007 5 Female 27 lb 5/17/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/9/2007 19 Male 164 lb 5/24/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Life Threatening 5/7/2007 Male 5/31/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/31/2007 9 Female 52 lb 5/29/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 4/9/2007 19 Male 167 lb 6/4/2007 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 5/21/2007 Female 20 lb 6/18/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/9/2007 19 Male 167 lb 6/7/2007 Physician United States
Primary
Secondary
Concomitant
Neutropenic Sepsis Other Serious 45 Female 6/21/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Death 1/6/2007 2 Female 6/18/2007 Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/3/2007 8 Female 43 lb 6/20/2007 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Death 3/19/2007 52 Female 6/23/2007 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Cardiac Failure Death 3/19/2007 52 Female 6/21/2007 Czech Republic
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 5/7/2007 39 Male 7/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 10/22/2006 11 Female 75 lb 7/2/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Life Threatening 5/7/2007 39 Male 7/11/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 5/7/2007 39 Male 7/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stem Cell Transplant Death 6/25/2007 Male 40 lb 7/3/2007 Physician United States
Primary
Secondary
Stomatitis Life Threatening 1/8/2007 40 Female 7/19/2007 Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious Female 7/30/2007 Physician Japan
Primary
Concomitant
Tooth Disorder Hospitalization 12/8/2006 17 Male 88 lb 8/2/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 5/7/2007 39 Male 8/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 3 Male 35 lb 8/28/2007
Primary
Secondary
Urinary Tract Infection Other Serious 21 Female 9/5/2007 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 6/3/2007 8 Female 43 lb 8/29/2007 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 66 Male 9/11/2007 Other Health Professional Portugal
Primary
Concomitant
Venoocclusive Disease Life Threatening 11/5/2007 15 Female 208 lb 12/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Lymphopenia Other Serious 12/11/2006 12 Female 148 lb 12/17/2007 Pharmacist Canada
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 3/21/2007 20 Male 1/3/2008 Japan
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Death 9/24/2007 46 Female 146 lb 1/24/2008 United Kingdom
Primary
Concomitant
Unevaluable Event Other Serious 56 Male 1/30/2008 Germany
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 54 Male 1/30/2008 Germany
Primary
Secondary
Unevaluable Event Other Serious 48 Male 1/30/2008 Germany
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 47 Female 1/30/2008 Germany
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 52 Male 1/30/2008 Germany
Primary
Secondary
Concomitant
Cytogenetic Abnormality Other Serious 52 Male 1/24/2008 Physician Germany
Primary
Secondary
Concomitant
Cytogenetic Abnormality Other Serious 47 Male 1/24/2008 Physician Germany
Primary
Secondary
Concomitant
Cytogenetic Abnormality Other Serious 54 Male 1/24/2008 Physician Germany
Primary
Secondary
Concomitant
Haematopoietic Stem Cell Mobilisation Other Serious 56 Male 1/24/2008 Physician Germany
Primary
Secondary
Concomitant
Cytogenetic Abnormality Other Serious 48 Male 1/24/2008 Physician Germany
Primary
Secondary
Concomitant
Cytogenetic Abnormality Other Serious 47 Female 1/24/2008 Physician Germany
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/16/2007 54 Female 3/6/2008 Japan
Primary
Concomitant
Vomiting Life Threatening 4/19/2007 16 Female 3/6/2008 Japan
Primary
Concomitant
Viraemia Other Serious 5/23/2007 31 Male 3/6/2008 Japan
Primary
Secondary
Concomitant
Wolff-parkinson-white Syndrome Hospitalization 8/6/2007 80 Male 3/6/2008 Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 66 Male 3/27/2008 Other Health Professional Portugal
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 3/11/2008 65 Female 3/26/2008 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/10/2008 Physician Switzerland
Primary
Secondary
Concomitant
Pyrexia Life Threatening 2/1/2008 Male 4/15/2008 Physician Switzerland
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 3/11/2008 65 Female 104 lb 4/11/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 2/1/2008 Male 5/1/2008 Physician Switzerland
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Other Serious 3/11/2008 65 Female 104 lb 4/25/2008 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 3/22/2008 5/14/2008 Other Health Professional United States
Primary
Secondary
Gastric Perforation Hospitalization 5/14/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 5/14/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 5/14/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 5/14/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 5/14/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Haemangioma Hospitalization 7/27/2007 44 Female 6/3/2008 Other Health Professional Hong Kong
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/19/2008 Lawyer United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/23/2008 Lawyer United States
Primary
Secondary
Concomitant
Leukopenia Other Serious 46 Female 6/19/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/24/2007 15 Male 7/10/2008 Japan
Primary
Concomitant
Infection Death 7/10/2008 Other Health Professional United States
Primary
Concomitant
Bone Pain Other Serious 8/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 31 Female 8/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Life Threatening 5/7/2007 39 Male 8/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 31 Female 8/21/2008 United Kingdom
Primary
Secondary
Concomitant
Sinusitis Other Serious 4/1/2002 Male 9/15/2008 Consumer France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/30/2008 64 Male 227 lb 1/5/2009 Other Health Professional United States
Primary
Concomitant
Pain Hospitalization 12/3/2008 1/9/2009 Other Health Professional India
Primary
Secondary
Pulmonary Mycosis Hospitalization 11/1/2008 69 Female 1/15/2009 Physician Germany
Primary
Secondary
Concomitant
Subileus Hospitalization 12/21/2008 59 Female 1/16/2009 Physician Germany
Primary
Secondary
Concomitant
Stem Cell Transplant Life Threatening 12/1/2008 58 Male 1/27/2009 Physician Italy
Primary
Secondary
Concomitant
Stem Cell Transplant Life Threatening 12/1/2008 58 Male 2/6/2009 Physician Italy
Primary
Secondary
Concomitant
Haematoma Life Threatening 1/22/2009 Female 2/13/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Death 2/7/2009 Male 159 lb 2/18/2009 Italy
Primary
Secondary
Concomitant
Clostridium Difficile Colitis 22 Female 2/19/2009 Other Health Professional United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/20/2008 62 Male 2/23/2009 Physician United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 3/2/2009 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 3/2/2009 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 3/2/2009 Physician United States
Primary
Secondary
Concomitant
Pneumonitis Death 3/2/2009 Physician United States
Primary
Secondary
Concomitant
Subileus Hospitalization 12/21/2008 59 Female 3/16/2009 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Mycosis Hospitalization 11/19/2008 69 Female 3/16/2009 Physician Germany
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 69 Male 3/20/2009 Other Health Professional Japan
Primary
Secondary
Subileus Hospitalization 12/21/2008 59 Female 3/23/2009 Physician Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 3/27/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 3/27/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/16/2008 64 Female 4/8/2009 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Septic Shock Death Male 4/27/2009 Physician Singapore
Primary
Concomitant
Neutropenic Colitis Other Serious 61 Female 5/15/2009
Primary
Secondary
Concomitant
Lactobacillus Infection Hospitalization 5/3/2009 1 Male 5/15/2009 Physician
Primary
Secondary
Concomitant
Pain Other Serious 12/3/2008 60 Female 5/20/2009 Physician United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 4/1/2002 Male 5/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Lactobacillus Infection Hospitalization 5/3/2009 1 Male 20 lb 6/1/2009 Physician United States
Primary
Secondary
Concomitant
Diverticulum Hospitalization 57 Female 6/4/2009 Physician United States
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 7/31/2006 6/9/2009 Other Health Professional United States
Primary
Secondary
Pollakiuria Other Serious 3/11/2009 6/9/2009 Physician United States
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 2/1/2004 61 Female 6/23/2009 Consumer Japan
Primary
Secondary
Paraesthesia Hospitalization 5/1/2008 69 Male 6/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pain Other Serious 11/26/2008 60 Female 7/6/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/16/2008 64 Female 7/9/2009 Physician Taiwan, Province Of China
Primary
Secondary
Pneumonitis Hospitalization 5/31/2009 7/9/2009 Other Health Professional United States
Primary
Secondary
Febrile Neutropenia Hospitalization 7/24/2009 50 Male 160 lb 7/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 9/23/2009 Male 255 lb 10/28/2009 United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 10/5/2009 11/9/2009 Physician United States
Primary
Secondary
Pleuritic Pain Hospitalization 9/14/2009 Female 11/9/2009 Physician United States
Primary
Secondary
Chills Other Serious 10/13/2009 11/12/2009 Physician United States
Primary
Secondary
Pancytopenia Life Threatening 8/7/2009 Female 103 lb 11/13/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 8/7/2009 Female 103 lb 11/13/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pleuritic Pain Hospitalization 9/14/2009 Female 11/19/2009 Physician United States
Primary
Secondary
Pancytopenia Life Threatening 8/7/2009 Female 103 lb 11/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Leukocytosis Hospitalization 67 Female 11/17/2009 Other Health Professional United States
Primary
Secondary
Febrile Neutropenia Hospitalization 10/11/2009 Male 134 lb 12/1/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/23/2009 Male 255 lb 12/2/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/23/2009 Male 255 lb 12/2/2009 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/11/2009 Male 134 lb 12/10/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Tachycardia Life Threatening 26 Female 146 lb 1/4/2010 Other Health Professional Portugal
Primary
Secondary
Concomitant
Herpes Virus Infection Hospitalization 10/17/2009 Male 1/4/2010 Physician Italy
Primary
Secondary
Concomitant
Tachycardia Life Threatening 26 Female 146 lb 1/8/2010 Other Health Professional Portugal
Primary
Secondary
Concomitant
Weight Increased Hospitalization Male 1/11/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Male 1/11/2010 Consumer United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 26 Female 146 lb 1/14/2010 Other Health Professional Portugal
Primary
Secondary
Concomitant

Drug Data