Cyclophosphamide combined with Etoposide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pleural Effusion Hospitalization 9 Male 12/28/2005 France
Primary
Secondary
Treatment Related Secondary Malignancy Other Serious 5/1/2001 65 Male 1/5/2006 Consumer United States
Primary
Concomitant
Renal Disorder Hospitalization 5/15/2000 58 Female 12/30/2005 Physician France
Primary
Secondary
Vomiting Other Serious 12/28/2005 Male 166 lb 1/5/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 9/18/2001 53 Male 95 lb 1/9/2006 Physician Japan
Primary
Secondary
Concomitant
Pseudomonas Infection Other Serious 12/20/2005 Male 153 lb 1/9/2006 United States
Primary
Secondary
Vomiting Other Serious 1/11/2006 Male 154 lb 1/12/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Death 6 Male 1/27/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6 Female 1/28/2006 Physician United States
Primary
Secondary
Tooth Extraction Other Serious 1/1/2005 Female 2/2/2006 Physician Germany
Primary
Concomitant
Sciatica Hospitalization 2/1/2005 56 Male 1/25/2006 Physician Canada
Primary
Secondary
Vomiting Other Serious 1/11/2006 Male 154 lb 2/6/2006 United States
Primary
Secondary
Concomitant
Constipation Other Serious 12/6/2005 Male 156 lb 2/7/2006 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/11/2006 Male 154 lb 2/8/2006 United States
Primary
Secondary
Concomitant
Constipation Other Serious 12/5/2005 Male 156 lb 2/8/2006 United States
Primary
Secondary
Concomitant
Mental Disorder Hospitalization Female 2/15/2006 Physician Germany
Primary
Concomitant
Vomiting Other Serious 2/2/2006 Male 143 lb 2/8/2006 United States
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Other Serious 3/1/2004 66 Male 2/6/2006 Physician United States
Primary
Secondary
Concomitant
Sputum Discoloured Hospitalization 1/26/2006 52 Male 2/13/2006 United States
Primary
Secondary
Transplant Life Threatening 7/2/2005 59 Male 139 lb 2/22/2006 Physician France
Primary
Secondary
Concomitant
Vomiting Other Serious 2/2/2006 Male 143 lb 2/21/2006 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 24 Male 165 lb 3/6/2006 Physician Norway
Primary
Concomitant
Staphylococcal Infection Hospitalization 11/23/2005 Male 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2004 63 Female 112 lb 3/2/2006 Physician Japan
Primary
Secondary
Concomitant
Rash Papular Hospitalization 2/20/2006 19 Male 3/7/2006 Physician Mexico
Primary
Concomitant
Rash Papular Hospitalization 2/20/2006 19 Male 3/7/2006 Physician Mexico
Primary
Concomitant
Metastases To Peritoneum Life Threatening 7/2/2005 59 Male 2/28/2006 France
Primary
Secondary
Peritoneal Carcinoma Life Threatening 7/2/2005 59 Male 139 lb 3/6/2006 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization Female 3/13/2006 Physician Germany
Primary
Concomitant
Hyperbilirubinaemia Other Serious 3/3/2006 Male 189 lb 3/3/2006 United States
Primary
Secondary
Swollen Tongue Hospitalization 6/4/2005 14 Male 3/6/2006 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 2/22/2006 Male 137 lb 3/9/2006 United States
Primary
Secondary
Concomitant
Syncope Hospitalization 7/13/2005 68 Male 3/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/1/2006 24 Male 165 lb 3/21/2006 Physician Norway
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 2/1/2006 52 Male 203 lb 3/17/2006 Physician Germany
Primary
Secondary
Concomitant
Metastases To Peritoneum Life Threatening 7/2/2005 59 Male 139 lb 3/16/2006 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Required Intervention 1/26/2006 19 Female 115 lb 3/10/2006 Physician United States
Primary
Secondary
Dehydration Other Serious 3/21/2006 Male 152 lb 3/22/2006 United States
Primary
Secondary
Trismus Hospitalization 8/2/2005 14 Male 3/20/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Rash Generalised Hospitalization 1/13/2006 59 Female 3/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 8/27/2005 63 Female 3/22/2006 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Death 1/1/2005 73 Male 3/22/2006 Physician France
Primary
Secondary
Drug Toxicity Death 3/30/2006 Other Health Professional Japan
Primary
Secondary
Pneumonia Required Intervention 3/30/2006 Other Health Professional Japan
Primary
Secondary
Pneumonia Required Intervention 3/30/2006 Other Health Professional Japan
Primary
Secondary
Pneumonia Required Intervention 3/30/2006 Other Health Professional Japan
Primary
Secondary
Drug Toxicity Death 3/30/2006 Other Health Professional Japan
Primary
Secondary
Sepsis Required Intervention Unknown 4/4/2006 Other Health Professional Japan
Primary
Secondary
Platelet Count Decreased Hospitalization 1/13/2006 71 Male 137 lb 4/3/2006 Physician France
Primary
Secondary
Concomitant
Rash Required Intervention 4/4/2006 Germany
Primary
Concomitant
Rectal Abscess Required Intervention 4/3/2006 Male 159 lb 4/4/2006 United States
Primary
Secondary
Vomiting Other Serious 3/20/2006 Male 152 lb 4/11/2006 United States
Primary
Secondary
Concomitant
Stem Cell Transplant Hospitalization 1/13/2006 59 Female 4/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Hypertonia Required Intervention 21 Female 3/29/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Pneumonia Respiratory Syncytial Viral Death 1/1/1999 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Cardiomyopathy Required Intervention 1/1/1999 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Required Intervention 1/1/1999 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Herpes Oesophagitis Required Intervention 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Infection Required Intervention 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Infection Required Intervention 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Drug Toxicity Required Intervention 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Pericarditis Required Intervention 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Pericarditis Required Intervention 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Facial Palsy Required Intervention 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Drug Toxicity Required Intervention 1/1/1999 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Required Intervention 1/1/1999 4/11/2006 Physician United States
Primary
Concomitant
Drug Toxicity Required Intervention 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Drug Toxicity Required Intervention 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 66 Male 4/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 66 Male 4/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2004 63 Female 112 lb 4/24/2006 Physician Japan
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 4/16/2006 Female 117 lb 4/28/2006 United States
Primary
Secondary
Febrile Neutropenia Hospitalization 4/19/2006 5 Male 40 lb 4/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Required Intervention 3/1/1991 5/4/2006 Physician Canada
Primary
Secondary
Concomitant
Pneumonitis Required Intervention 3/1/1991 5/4/2006 Physician Canada
Primary
Secondary
Concomitant
Stenotrophomonas Infection Required Intervention 3/1/1991 5/4/2006 Physician Canada
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 66 Male 5/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Laboratory Test Abnormal Other Serious 4/30/2006 Female 186 lb 5/4/2006 United States
Primary
Secondary
Concomitant
T-cell Lymphoma Death 66 Male 5/12/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/4/2006 Male 189 lb 5/10/2006 United States
Primary
Secondary
Pyrexia Hospitalization 2/1/2006 24 Male 165 lb 5/15/2006 Physician Norway
Primary
Secondary
Concomitant
Myocardial Fibrosis Other Serious 55 Male 5/11/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention 1/26/2006 19 Female 115 lb 5/3/2006 Physician United States
Primary
Secondary
Neutropenic Sepsis Hospitalization 4/19/2006 5 Male 40 lb 5/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Hypertension Hospitalization 2/27/2006 3 Female 29 lb 5/18/2006 Other Health Professional France
Primary
Secondary
Stem Cell Transplant Other Serious 2/13/2005 66 Female 5/15/2006 Physician Germany
Primary
Concomitant
Melaena Other Serious 60 Female 5/22/2006 Australia
Primary
Secondary
Concomitant
Virus Urine Test Positive Hospitalization 4/19/2006 5 Male 40 lb 5/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 4/1/2006 Male 165 lb 6/2/2006 Physician Spain
Primary
Concomitant
Coronary Artery Surgery Hospitalization 4/26/2005 69 Male 4/28/2006 Other Health Professional United States
Primary
Secondary
Blood Bilirubin Increased Other Serious 1/7/2005 3 Female 5/24/2006 Spain
Primary
Concomitant
Febrile Neutropenia Other Serious 6/5/2006 41 Female 108 lb 6/7/2006 United States
Primary
Secondary
Neoplasm Recurrence Hospitalization 1/1/2006 21 Female 6/7/2006 Other Health Professional Netherlands
Primary
Secondary
Tooth Extraction Other Serious 1/1/2005 Female 6/16/2006 Other Health Professional Turkey
Primary
Concomitant
Respiratory Disorder Death 2/26/2004 6 Male 6/16/2006 Consumer Japan
Primary
Secondary
Sideroblastic Anaemia Other Serious 4/1/2006 Male 165 lb 6/19/2006 Physician Spain
Primary
Concomitant
Pneumonia Required Intervention 64 Male 6/16/2006 Physician Germany
Primary
Concomitant
Pneumonia Death 6/15/2006 Austria
Primary
Secondary
Sideroblastic Anaemia Other Serious 4/1/2006 Male 165 lb 6/23/2006 Physician Spain
Primary
Concomitant
Pancytopenia Other Serious 2/14/2002 33 Male 130 lb 6/20/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/14/2006 Male 189 lb 6/19/2006 United States
Primary
Secondary
Vomiting Hospitalization 6/14/2006 Male 170 lb 6/19/2006 United States
Primary
Secondary
Treatment Related Secondary Malignancy Other Serious 9 Female 7/6/2006 Other Health Professional United States
Primary
Secondary
Weight Increased Hospitalization 6/30/2006 Male 27 lb 7/3/2006 United States
Primary
Secondary
Sepsis Hospitalization 5/10/2006 49 Female 6/29/2006 France
Primary
Secondary
Renal Tubular Disorder Hospitalization 2/27/2006 3 Female 29 lb 7/13/2006 Other Health Professional France
Primary
Secondary
Renal Cell Carcinoma Stage Unspecified Other Serious 9 Female 6/26/2006 Other Health Professional United States
Primary
Secondary
Weight Decreased Hospitalization 1/1/2000 50 Male 7/12/2006 United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/20/2006 1 7/10/2006 Physician France
Primary
Secondary
Infection Hospitalization 5/16/2006 Physician Italy
Primary
Secondary
Infection Hospitalization 5/16/2006 Physician Italy
Primary
Secondary
Infection Hospitalization 5/16/2006 Physician Italy
Primary
Secondary
Infection Hospitalization 5/16/2006 Physician Italy
Primary
Secondary
Infection Hospitalization 5/16/2006 Physician Italy
Primary
Secondary
Wound Debridement Other Serious 1/1/2003 61 Male 187 lb 7/21/2006 Physician Germany
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 9 Female 7/13/2006 United States
Primary
Secondary
Ventricular Hypertrophy Death 4/10/2004 70 Male 7/20/2006 Physician United States
Primary
Secondary
Renal Failure Life Threatening 8/19/2004 47 Female 7/25/2006 Physician United States
Primary
Secondary
Concomitant
Mucoepidermoid Carcinoma Other Serious 13 Female 7/25/2006 Physician Turkey
Primary
Secondary
Primitive Neuroectodermal Tumour Death 10 Male 7/25/2006 Physician Turkey
Primary
Secondary
Therapeutic Response Decreased Other Serious 37 Female 7/25/2006 Physician Japan
Primary
Secondary
Convulsion Other Serious 7/26/2006 Physician United States
Primary
Concomitant
Soft Tissue Disorder Other Serious 7/26/2006 Physician United States
Primary
Concomitant
Soft Tissue Disorder Other Serious 7/26/2006 Physician United States
Primary
Concomitant
Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Staphylococcal Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Enterobacter Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Bacterial Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Soft Tissue Disorder Required Intervention Unknown 7/26/2006 Physician United States
Primary
Concomitant
Soft Tissue Disorder Required Intervention Unknown 7/26/2006 Physician United States
Primary
Concomitant
Convulsion Other Serious Unknown 7/26/2006 Physician United States
Primary
Concomitant
Convulsion Other Serious Unknown 7/26/2006 Physician United States
Primary
Concomitant
Convulsion Other Serious Unknown 7/26/2006 Physician United States
Primary
Concomitant
Treatment Related Secondary Malignancy Other Serious 15 Female 8/3/2006 Consumer United States
Primary
Secondary
Respiratory Failure Required Intervention 20 Female 7/24/2006 Other Health Professional Japan
Primary
Secondary
Treatment Related Secondary Malignancy Death 10 Male 8/3/2006 Consumer United States
Primary
Secondary
Treatment Related Secondary Malignancy Other Serious 13 Female 8/3/2006 Consumer United States
Primary
Secondary
Adverse Event Death 7/27/2006 Physician Germany
Primary
Secondary
Neutropenia Life Threatening 5/5/2006 75 Male 7/31/2006 Physician France
Primary
Concomitant
Tumour Perforation Required Intervention 20 Female 8/1/2006 Other Health Professional Japan
Primary
Secondary
Chest Pain Hospitalization 3/25/2006 73 Female 137 lb 7/31/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12/30/2004 75 Male 8/2/2006 Physician France
Primary
Secondary
Concomitant
Rash Hospitalization 11/11/2005 Male 123 lb 8/11/2006 Physician Belgium
Primary
Concomitant
Syncope Hospitalization 7/14/2006 63 Male 166 lb 8/7/2006 Physician United States
Primary
Secondary
Solitary Kidney Secondary Other Serious 9 Female 8/14/2006 Physician United States
Primary
Secondary
Stem Cell Transplant Required Intervention 4/21/2006 63 Male 170 lb 8/21/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Required Intervention 7/21/2006 6 Female 47 lb 8/22/2006 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8 Male 8/31/2006 Other Health Professional France
Primary
Secondary
Concomitant
Virus Urine Test Positive Required Intervention 7/21/2006 6 Female 47 lb 9/1/2006 United States
Primary
Secondary
Concomitant
Renal Hypertension Hospitalization 2/27/2006 3 Female 29 lb 9/6/2006 Consumer United States
Primary
Secondary

Drug Data